Six MaRS high-potential clients made the MaRS DealBook as we traveled to the 2009 Life Sciences and Healthcare Venture Summit in NYC. All participants were selected by a panel of US venture capital firms. Read on about some of our top life sciences clients.

1. dealbook
Life Sciences
& Healthcare
Venture
Summit
New York
09
dealbook life Sciences & Healthcare Venture Summit - New York 2009

2. Table of Contents
about MarS 01
Venture Profiles
biomedical
Photometrics 03
Colibri Technologies 04
INTerxVeNT 05
MedCurrent 06
Profound Medical 07
rejuven8 laboratories 08
Somnaform 09
key Contacts 10
Notes 12
dealbook life Sciences & Healthcare Venture Summit - New York 2009

3. About MaRS
It is my pleasure to present the third
MarS dealbook, created to highlight our
presenting companies at the life Sciences
bUIldING CaNada’S NeXT GeNeraTIoN
& Healthcare Venture Summit in New York,
2009.
oF Global TeCHNoloGY CoMPaNIeS
MarS is a large scale innovation centre - located in Toronto
The Seven companies in this guide are
and networked across ontario - focused on building Canada’s
but a fraction of the varied life Sciences next generation of technology companies.
and Healthcare ventures we work with at MarS. MarS is
establishing itself as a major deal-flow engine in the life
Sciences & Healthcare sector, with an emphasis on early-
stage companies.
MarS is focused on developing young companies and
connecting entrepreneurs to the right international markets
and investment capital.
I invite you to speak with our MarS team at the Summit
in New York to learn more about our unique approach. or
get to know us online at www.marsdd.com. I look forward
to bringing a fresh group of MarS ventures for future life
Science and Healthcare events.
Growing to an impressive 1.5 million sq. ft., MarS is located
in Toronto’s discovery district, Canada’s largest scientific
research hub, surrounded by a creative urban community
and adjacent to leading financial institutions.
Since opening in 2005, MarS has attracted international
Veronika litinski attention due to its scale, the quality of its discovery pipeline,
Practice lead, life Sciences & Healthcare, MarS its collaborative model, and its comprehensive offering of
best-in-class services and programs designed to accelerate
the growth of emerging companies.
MarS works closely with entrepreneurs to grow and scale
their ventures into global market leaders – in life sciences and
health care, digital media and ICT, clean technology, advanced
materials and energy, as well as innovative social purpose
businesses and social enterprises. MarS provides business
advice and mentorship, market intelligence, entrepreneurship
education, seed capital and access to critical talent, customer
and partner networks.
dealbook life Sciences & Healthcare Venture Summit - New York 2009 01

4. Venture Profiles
a Model For MarkeT SUCCeSS 550 Parkside drive, Unit b6
waterloo, oN Canada N2l 5V4
PeoPle | exceptional business advisory & Market Insight www.confocal.com
we provide specialized business advisory and mentorship
as well as research insight and capital connections that are Biomedical photometrics inc.
essential to emerging technology companies. biomedical Photometrics Inc. (bPI) develops and
ProGraMS | Specialized educational & Networking Programs sells multispectral tissue scanners for digital
pathology, biomarker profiling, and a wide range
we provide programs that provide the business fundamentals of research applications. bPI’s current product,
of entrepreneurship plus access to specialized educational the TISSUescope™ 4000, is a dual brightfield-
resources and networking events. fluorescence whole slide scanner for tissue
PlaCe | world Class research & Collaboration Facilities imaging in clinical and other research markets.
we house and incubate top technologists and scientists in an bPI’s TISSUescopes use patented technology
environment optimized for innovation through specialized that provides a field of view that is hundreds of
lab/test facilities and collaborative workspaces. times that of a microscope. when combined with
automatic focus, tissue finding and the ability
to image multiple fluorophores simultaneously,
bPI’s TISSUescopes allow a wide variety of tissue
Since January 2006, MaRS has worked with
specimens and sizes to be digitized automatically.
1500 Companies bPI manufactures and sells complete
instruments, including software to acquire and
store digital images automatically. objective
Pathology ltd. has developed a viewer for bPI’s
scanners and an image server to serve bPI’s
images locally or over the internet.
CoMPeTITIVe adVaNTaGe
The patented TISSUescope™ instruments
perform both brightfield and simultaneous multi-
spectral fluorescence imaging of tissue. when
combined with high sensitivity, high dynamic
POrTfOLIO BrEAkdOwN range, and fast scan speed in fluorescence, the
instruments have a major competitive advantage
40% Information and Communication Technology in biomarker profiling, which will be essential for
22% Life Sciences & Healthcare quantitative analysis in pathology. The world’s
19% Social Purpose largest pathology image (breast mastectomy) can
9% Cleantech & Environmental Technology be viewed on our website at http://confocal.com/
3% Materials and Advanced Manufacturing reSoUrCeS/ImageGallery.html.
2% Agriculture CUrreNT FUNdING
5% Other raised: $3M
SeekING
$5M
02 dealbook life Sciences & Healthcare Venture Summit - New York 2009 03

5. COLIBRI
Suite 209-170 Mcewan drive
75 oriole rd #204 bolton, oN l7e 4C8
Technologies Toronto, oN M4V 2e9 www.intervent.com
Colibri Technologies inTeRxVenT
ablation procedures can effectively treat INTerxVeNT Canada helps organizations reduce
patients with atrial fibrillation (aF), the medical costs and improve productivity.
most common arrhythmia in the western The company is well-positioned to capitalize
world. However, atrial fibrillation ablation is on growing investment in preventative health
a challenging 3-4 hour procedure performed interventions, which have a demonstrated
by specialized cardiologists. It has a 4-6% positive return on investment. Its proprietary
complication rate, considerable x-ray exposure platform unites disease management and
and a success rate of only 50-75%. Many prevention information, tools and resources into
physicians use intracardiac echocardiography a solution that organizations provide at a low
(ICe) to facilitate their procedures, although this per-user cost online and by phone.
an expensive technology, adding up to $2500 to
the other $4000+ spent on disposable devices CoMPeTITIVe adVaNTaGe
for these procedures. Corporations, government agencies, cardiac
rehabilitation facilities, hospitals and academic
CoMPeTITIVe adVaNTaGe institutions use INTerxVeNT to identify health
Colibri has licensed over 4 patents from risks in large groups; deliver comprehensive
Sunnybrook Health Sciences Centre relevant and customized self-help and coach-assisted
to image guided therapy. This includes broad programs to improve health; and report health
coverage of our 3d image scanning mechanism statistics to enhance decision-making and
and incorporation of this mechanism into resource utilization. with more than 14 years of
both standalone catheters and integration of use by over 190 organizations, INTerxVeNT’s
the scanning core into a range of therapeutic scientifically proven efficacy is supported by
catheters. Colibri’s founders and management more than 80 peer-reviewed journal articles
have a history of successful commercial and manuscripts, and has been used by over 1.5
development of medical imaging and million participants.
therapeutic devices and world-class experience
in ultrasound devices. CUrreNT FUNdING
raised: $2M
CUrreNT FUNdING
raised: $150k Private: $500k Public SeekING
$3M
SeekING
$3M
04 dealbook life Sciences & Healthcare Venture Summit - New York 2009 05

6. 55 Gilgorm rd. 4040-3080 Yonge St.
Toronto, oN M5N 2M4 Toronto, oN M4N 3N1
www.medcurrent.com www.profoundmedical.com
medCurrent inc. profound medical inc.
radiology, the fastest growing sector in CoMPeTITIVe adVaNTaGe
healthcare, is fraught with spiralling costs due There are major Quality-of-life issues with
to an explosive increase in utilization. This is all existing approaches to Prostate Cancer.
leading payers, both private and government, to due primarily to over-treatment through
actively seek out solutions. It is well known that inaccurate and imprecise techniques, there are
a significant number of radiology studies are unacceptable levels of post-operative impotence
unnecessary but still get performed, a wasteful and incontinence.
situation but one that occurs for a number of CoMPeTITIVe adVaNTaGe
reasons: doctors practicing defensive medicine, Profound’s interventional MrI-guided, trans-
patients’ demand for services and physicians urethral ultrasound medical device provides the
often being unaware of the optimal test to order. least invasive treatment, in the shortest possible
MedCurrent has developed orderrightTM is time, as an outpatient procedure, offering
based on rules developed by the american incomparable accuracy and precision.
College of radiology, is a simple to use web-
based tool that guides the ordering doctor to Further, the accuracy of this device offers
the best test to order for each specific patient. surgeons and patients unparalleled treatment
Such decision support tools are just as effective planning options, ranging from matching the
as rbMs but are less expensive and much more existing radical Prostatectomy “gold standard”
favorably accepted by physicians. of treating a whole prostate, to leading the next
generation of focal therapy whereby clinicians
CoMPeTITIVe adVaNTaGe will target just the diseases, leaving much of
orderrightTM allows users to easily modify the the remaining healthy gland unadulterated and
rules to suit their local needs. In addition, it also fully-functional.
provides protocol support, which communicates
the very specific way in which the study CUrreNT FUNdING
should be conducted for each patient. as well, raised: $1.75M
orderrightTM can be utilized for all medical Current Investors: Genesys Capital
specialties, not just radiology. SeekING
CUrreNT FUNdING $7M
raised: $1.5M
Current Investors: angels
SeekING
$2M
06 dealbook life Sciences & Healthcare Venture Summit - New York 2009 07

7. 9-6975 MTC Circle, Suite 419 2 bloor Street west, Suite 700
Mississauga, oN l5N 2V7 Toronto, oN M4w 3r1
www.rejuven8labs.com www.somnaform.com
Rejuven8 Laboratories inc. somnaform Corp.
rejuven8 labs is a unique, intellectual property Somnaform Corp. is a medical devices company
(IP)-driven Green life Sciences enterprise focused on designing, manufacturing and
focused on r&d of eco-safe products, services, distributing low tech, affordable medical devices
and technologies. we are an idea-powered internationally, including accessories to increase
Company that creates solidly unique earth-
compliance, comfort while reducing risks for
friendly consumer products in 8 growth
adults, children and infants.
industries. our products were formulated
entirely using natural ingredients that are CoMPeTITIVe adVaNTaGe
Generally recognized as Safe (GraS). our our competitive advantage is lean operations
solidly unique, proprietary products work as well and manufacturing, defensible intellectual
as or better than products currently marketed property with large margins and reduced
within the niche Green Global Market Space. competition with innovative, patented products.
also, non-exclusive distribution arrangements
CoMPeTITIVe adVaNTaGe
with large international medical distributors
• The only green product that kills by have been established. our opportunity is
targeting the growth zone at root: No to expand market share in very large and
overall spray is necessary, thus the product growing international market with effective
easier to use and apply. No collateral marketing and pursuing additional licensing and
damage to desirable plants when used as distribution opportunities internationally.
directed.
CUrreNT FUNdING
• Faster-acting and longer-lasting: Generally, raised: $150k
weeds and unwanted grasses die within 1 Current Investors: Friends & Family
hour and re-growth does not occur for at
SeekING
least 1 month.
$2M
• More powerful: Completely kills all weeds
tested to date, including weeds with tough
waxy cuticles, like the common milkweed.
• Immediately biodegradable: weedphyter®
leaves no harmful soil residue.
• rain-fast: No run-off contamination and
does not persist long enough to affect
waterways.
CUrreNT FUNdING
raised: $13k
SeekING
$500k
08 dealbook life Sciences & Healthcare Venture Summit - New York 2009 09

8. Key Contacts
MaRS CONTACTS
Veronika litinski, Practice lead,
life Sciences & Healthcare
vlitinski@marsdd.com
MarS discovery district
MarS Centre, South Tower
101 College Street, Suite 100
Toronto, ontario, Canada M5G 1l7
T 416.673.8113
F 416.673.8181
www.marsdd.com
COMPANY CONTACTS
biomedical Photometrics Inc.
a.e. (Ted dixon), Ceo & Chairman
aedixon@confocal.com
519.886.9013 x22
Colibri Technologies
brian Courney, Ceo
bcourtney@rogers.com
416.575.6531
INTerxVeNT
Mel barsky
mel@intervent.ca
416.578.6352
MedCurrent Inc.
Steve Herman, Ceo
steve.herman@medcurrent.com
416.904.7782
Profound Medical Inc.
Paul Chipperton, Ceo & Coo
pchipperton@profoundmedical.
com
416.605.7470
rejuven8 laboratories Inc.
Sheldon Joseph, Ceo
sheldon@rejuven8labs.com
416.606.8803
Somnaform Corporation
Jonathan aikman, President &
General Counsel
jaikman@somnaform.com
416.323.6897
10 dealbook life Sciences & Healthcare Venture Summit - New York 2009

9. www.marsdd.com