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Letting the Genes out of the Bottle: Making the most of free bioinformatics information Don MacMillan University of Calgary Libraries and Cultural Resources Calgary, Canada
Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Introduction ,[object Object],[object Object],[object Object],[object Object]
Bioinformatics ,[object Object],[object Object],[object Object],[object Object]
What is Bioinformatics? ,[object Object],[object Object],[object Object],[object Object],[object Object]
Why use Bioinformatics? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Challenges for Librarians ,[object Object],[object Object],[object Object],[object Object]
Biology 311 ,[object Object],[object Object],[object Object],[object Object]
Sample Genetic Diseases ,[object Object],[object Object],[object Object],[object Object],[object Object]
Sample Questions ,[object Object],[object Object],[object Object],[object Object]
Online Mendelian Inheritance in Man (OMIM) ,[object Object],[object Object],[object Object],[object Object]
Search for Disease topic
Cystic Fibrosis Gene
Detailed Gene and Protein  Information
BLAST-Basic Local Alignment Search Tool ,[object Object],[object Object],[object Object]
 
Assessment ,[object Object],[object Object],[object Object]
Lessons Learned ,[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusion ,[object Object],[object Object],[object Object],[object Object],[object Object]
Bioinformatics Links ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Related Links ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Iatul june1 2009

Notes de l'éditeur

  1. Quality through Innovation We, like other academic libraries have had to revise o r supplement our traditional information literacy initiatives and reference services as these approaches have become less effective or unsustainable in an increasingly online environment. (Library is no longer the starting point for academic research)
  2. Impetus for introduction Other data repositories, patents
  3. Over the past few decades, major advances in the field of molecular biology, coupled with advances in genomic technologies, have led to an explosive growth in the biological information generated by the scientific community. These tools enable scientists to locate and analyze gene and protein data Combines the fields Biology, Mathematics and Computer Science-manages a vast amount of sequencing data GenBank core resource, 83 million sequence records and 86 billion pairs of nucleotides EMBL- The European Molecular Biology Laboratory DDBJ- DNA Databank of Japan Human diseases may nor be in same form as animals but usually sufficient data for researchers to make inferences about the process in humans
  4. Bioinformatics provides access to the enormous amounts of data produced by genome researchers so that it can be analyzed and interpreted by researchers Excellent marketing tool for other Biology IL sessions-review IL skills
  5. Perception that librarians have sufficient subject knowledge to provide assistance or have expertise with Bioinformatics Tools Need to develop fluencies, good marketing tool for other senior level biology classes Key is collaboration – librarian has knowledge of how databases function and effective pedagogies for using info resources Faculty knowledge of content-model assignment on real world experience
  6. 14 questions
  7. Detailed descriptions on over 80 genetically-inherited diseases are available in the Genes and Disease database
  8. Inheritance pattern of the disease What is the name of gene(s) believed responsible for the disease What types of mutations have been discovered in this gene What chromosome is the gen located on
  9. Bioinformatics are complex containing more information than students need Success breeds confidence – completing one task in a database means they will likely use or try another Using a database to ask “real world” questions lends credibility to exercise-make sure they are rewarded for use Read screens carefully-extract what they need and use built-in features to manipulate the data Questions will arise during the session with searching and interpreting the data that both experts may be required to help with
  10. Learned more Developing closer partnership with faculty has provided insights how Biologists approach information so I am better able to understand their collection needs and IL requirements Librarian brings understanding of novice researcher this ensuring that explanations are clear and assignments are doable and IL builds on existing literacy skills