3. What is medicinal
chemistry?
The science that deals with the
discovery or design of new
therapeutic chemicals and the
development of these chemicals into
useful medicine
4. A Father of Modern
Medicinal Chemistry
Edward E. Smissman,
University of Kansas
Smissman Award of
the ACS Division of
Medicinal Chemistry
named in his honor
5. Everyday drugs…..
Still produce a response;
many are addictive
Caffeine
Sugar
Nicotine
Alcohol
Food additives
Vitamins
Herbs
6. cocaine
Besides being an extremely addictive
and dangerous narcotic, cocaine has
some medicinal use. Cocaine has been
used as a local anesthetic for eye and
nasal surgery.
The vasoconstriction helps reduce
bleeding and the systemic circulation
of cocaine (into the heart,
specifically).
7. The tobacco plant
When tobacco smoke is inhaled, the
nicotine passes quickly to every organ
of the body.
The brain and nervous system are
stimulated by small doses and
depressed by larger ones.
Nicotine increases the heart rate and
the blood pressure, and may contribute
directly to the excess of thrombosis
and atheroma in smokers.
8. Heroin
Diamorphine
One of the best painkillers (“hero”)
1898: on market
1903: withdrawn (addictive
properties)
Today: still used
9. DRUGS
"all chemicals other than food that
affect living processes."
The drug is a medicine. However, if a
drug causes a harmful effect on the
body, the drug is a poison.
The same chemical can be a medicine
and a poison depending on conditions
of use and the person using it.
10. DRUGS CLASSIFICATION
Drugs can be classified according to
various criteria
Chemotherapeutic agents - used to
cure infectious diseases and cancer.
(Sulfa drugs, Antibiotics)
Pharmacodynamic agents - used in
non-infectious diseases (Cholinergic,
Adrenergic, Hallucinogenic, Sedatives)
Miscellaneous agents (Narcotic
Analgesics, Local Anesthetics)
11. DRUGS NAME
Drugs have three or more names
including a:
chemical name- rules of
nomenclature of chemical
compounds.
brand or trade name- selected by
the manufacturer
generic or common name-
common
established name
12. MODE OF DRUG ACTION
One major problem of pharmacology is that no drug
produces a single effect.
primary effect is the desired therapeutic effect.
Secondary effects are all other effects beside the
desired effect which may be either beneficial or harmful.
Drugs are chosen to exploit differences between
normal metabolic processes and any abnormalities
which may be present.
14. SIDDHA
The father of Siddha Vaidyam or
Siddha Medicine. Agasthiya
Guru
Siddha Medicines are natural and
safe without any side effects.
Its a way of life formulated by
Siddhars through their vision and
realisation for getting peace for
the mind, health for the physical
body .
15. ANANAS COMOSUS
English Name : Pine apple
Family Name : Bromeliaceae
Chemical constituents : Bromelin
Action : Styptic, Emmenagogue, Anthelmintic,
Vermicide,
Diaphoretic, Aperient
Uses in Siddha :
It is useful in vomiting,gastralgia,jaundice .
It’s juice is processed into syrup and it helps
in vomiting, excessive thirst, leucorrhoea
and other pitha disorders.
16. CITRUS AURANTIUM
English Name : Sour orange, bitter orange
Family Name : Rutaceae
Chemical constituent : d-linalool and glucoside hesperidin
Action : Refrigerant, Stomachic, Tonic
Uses in Siddha :
? It is a blood purifier.
? It reduces secretion of excessive bile and
improves digestion and health.
? It also helps in curing cough, diabetes
mellitus, chest pain, liver disorder.
17. ANNONA SQUAMOSA
English Name : Custard apple, Sugar apple
Family Name : Annonaceae
Chemical constituent : Seeds has an acrid principle
Action : Coolant, Tonic, Haematinic
Uses in Siddha :
It is prepared as syrup and it helps to reduce
heat in the body.
18.
19. AYURVEDA
"the knowledge for long life"
Ayurveda stresses the use of plant-
based medicines and treatments.
All diseases originate as an inbalance
in the digestive system.
Up to 80% of people in India use either
Ayurveda or other traditional
medicines.
20. PAPAYA
Boosts up the immune system.
Increases quality of proteins in whole
organism.
Encourages the renewal of muscle
tissue.
Papaya can be use also externally as a
treatment for skin wounds that don’t
heal quickly, for this you can use
papaya peel or ointments made out of
papaya.
21. LEMON
Mouth ulcer and Throat
infection.
Reduce Body
Fat Stomach upset
Constipation
Body pain
22. JACKFRUIT
The Chinese consider jackfruit pulp
and seeds tonic, cooling and
nutritious, and to be "useful in
overcoming the influence of alcohol
on the system.“
The seed starch is given to relieve
biliousness and the roasted seeds are
regarded as aphrodisiac.
The root is a remedy for skin diseases
and asthma
23. ALLOPATHY
"The term 'allopathy' was
invented by German physician
Samuel Hahnemann ...
"Scientific medicine at the
beginning of the [19th] century
was heroic medicine.“
24. ACETAMINOPHEN
Paracetamol
They are widely used for the
treatment of inflammatory disorders
and painful conditions
Paracetamol is a drug used as a
painkiller (analgesic) and for
reducing fever (antipyretic)
Other names are panadol & tylenol
in US
25. Benadryl
Diphenhydramine Hydrochloride
Benadryl is a medication that is used
for a variety of different purposes.
It can be used to treat insomnia,
sneezing and runny nose due to the
common cold.
Healthcare providers may also
occasionally recommend off-label
uses for Benadryl such as for treating
morning sickness, coughing, and
autism.
27. TULSI
TULSI MEANS IN COMPARABLE
IT CALLED AS QUEEN OF HERBS
TULSI IS AN ANTI-INFLAMMATORY AND
ANTI–OXDIANT
28. TULSI CONTENTS
OCIMUM SANCTUM
TULSI CONTAINS
ASCORBIC ACID
CAROTENE
ONE FORM OF VITAMIN -C
29. AMLA
Used in ayurvedha
Contains vitamin C
20 times the amount of vitamin C in
oranges
prevents jaundice indigestion
regulates the blood sugar
30. GUAVA
Contains calcium , iron, protien
have more amount of vitamin A
prevents poor circulation
cataracts to help kidney to eliminate the
waste
reduce the risk of cancer and cholestrol
31. TURMERIC
Used in sidha
Contains resin,fatty substances
Root contains 10% of glucosoid and turpethin
Contains mixture of phenol compounds
called curcumin
Having starch,protien,vitamin A,etc.
