1. PANCREAS

2. CONTENTS
• 1) Physiological Aspect Of Pancreas: As Endocrine & Exocrine
• 2) Regulation of Pancreatic Secretion
• 3) Acute Pancreatitis:
a) Def , b) Causes, c) Types: Insterstitial ( mild form) &
Necrotizing ( Severe form).
d) Amylase & Lipase at a Glance & role in Acute Pancreatitis
e) Laboratory findings: WBC, BSL, Ca++, LDH, HCT, BUN &
Creat.,,Etc
f) Severity of Acute Pancreatitis, Treatment & Complications….
4) Chronic Pancreatitis: Def. Causes ( TIGAR-O), Treatment.

4. Other Uncommon Causes

5. Recurrent Pancreatitis…..

6. Diagnostic Criteria for Ac. Pancreatitis
• The Diagnosis of Acute pancreatitis requires
two of the following:
1) Typical Abdominal pain.
2) > 3times elevation in serum amylase
and/or lipase level,
3) Confirmatory findings on cross-sectional
abdominal imaging (CECT Scan)

7. Criteria for Severity

8. Complications of Ac. Pancreatitis
Local Complication Systemic Complications
1) Necrosis ( MC) 1) CNS
2) Pseudocyst ( Mild Hmmrge 100%) . 2) CVS
3) Pancreatic Ascitis 3) RS
( Increased Proteins, Amylase in fluid) 4) Renal
4) Obstructive Jaundice 5) GIT
6)Hematological .
7) Metabolic :
( Hyperglcemia, Hypocalcemia,HyperTG, Purtschers
Retinopathy)

9. All s/o of Severity……
• Ransons Score: >= 3 ( More of Prognostic Marker)
• CT severity Score >= 6
• C- Reactive Protein >= 150 units
• APACHE score >= 8
• Glass gow Coma >= 3

11. Chronic Pancretitis…..