CSHGP Special Studies in Nepal and Ethiopia_Sampath_Gannon_5.2.12
1. Plan International
Bhagawan Das Shreshta, Harpreet Anand, Vidya Sampath
May 2, 2012 – Core Group Spring Meeting
02 May
2012 1
2. What does the Science tell us?
What did the Nepal Government want to do?
What was Plan International’s role in this?
What are the policy implications and next
steps?
Promising Futures,
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05/07/12 2
3. Recently-cut cord is common portal of entry
for bacteria
Causes newborn sepsis and death from serious
infection
Bacteria can enter bloodstream
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Community by Community
05/07/12 3
4. 4% CHX ointment reduces:
- severe cord infection (by 65%)
- neonatal mortality (by 23.5%; 34% if applied on
day of delivery)
- incidence of severe infection of umbilicus
stump (by 70 - 80%)
[source: Mullany et. al, 2006]
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5. Current neonatal mortality rate: 33 deaths per
1000 live births/23,000 neonatal deaths every
year;
72% of infant deaths; 61% of U5 deaths;
Umbilical cord infection is about 62% of local
bacterial infection;
Pilot CHX programs in four districts: Banke,
Bajhang, Jumla, and Parsa.
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Community by Community
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6. Global organization, established in 1937, that
works side by side with communities in 50
developing countries to end the cycle of
poverty for children;
In Nepal since 1978
15 districts
2 million people
Four CSHGP grants
(1997 – 2011)
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6
7. “Local Innovation for Better Outcomes for
Neonates” (2006-2011);
Key factors for success: Pregnant Women’s
Groups (PWGs), facilitated by Female
Community Health Volunteers (FCHVs);
10-12 pregnant women in each group,
facilitated by 1 FCHV;
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9. FCHV role:
- Motivate women to utilize MCH services;
- Distribute pre-natal medicines;
- Present at childbirth and immediate care of
neonate;
- Home visits after birth (1st, 3rd, 7th & 29th
days);
- Diagnoses and Referrals.
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11. Measure the coverage and compliance in the
application of CHX at the community level;
CHX supplied in a tube marketed under the
brand name “Kawach”;
Participants were informed on proper usage.
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05/07/12 11
13. Coverage rate: 82.7% of newborns had CHX
applied to their umbilical cord;
Compliance rate: 66.4% (of above) applied
CHX correctly;
97% used full tube of CHX; 2% partial tube.
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05/07/12 13
17. Women who belong to PWGs were 1.3 times more
likely to have correctly applied CHX, than those
who were not;
None of the women in PWGs reported using
harmful substances on stump, as per usual local
practice, such as cow dung, oil, or turmeric
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Community by Community
05/07/12 17
18. Plan Nepal, through its organizational funds,
continues the CHX program by integrating it with
Community Based Newborn Care Program
(CBNCP) in Rautahat district;
As of April 30, 2012:
- 8 districts completed CHX integration with CBNCP
- 7 districts ongoing
- Planning has commenced to add on 5 more
- By June 2013, total CHX coverage goal: 45 out of 75
districts in Nepal.
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Community by Community
05/07/12 18
19. The 4% CHX lotion is listed in the essential drugs
list of Ministry of Health and Population of Nepal;
CHX lotion is free of cost;
CHX will be scaled up and integrated with CBNCP
all over Nepal
The CBNCP training manual and reporting formats
have been revised to include CHX components.
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Community by Community
05/07/12 19
20. WHO recommendation: “dry cord care is
general recommendation, but when adequate
hygiene cannot be assured in household
environment, CHX should be used”;
USAID brief: “there is sufficient evidence to
recommend introduction of 4% chx cord
cleansing, in place of dry cord care, as a
strategy to reduce neonatal mortality in
settings of high neonatal mortality and poor
hygiene”
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Community by Community
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21. CHX Working Group:
http://www.healthynewbornnetwork.org/topic/chlorhexidine
USAID Technical Brief: www.usaid
.gov/our_work/global_health/mch/.../chx_issuebrief.pdf
Johns Hopkins page on CHX:
http://www.jhsph.edu/publichealthnews/press_releases/2012/baqui_cord
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Community by Community
05/07/12 21
Recently-cut cord is a common portal of entry for invasive bacteria that cause newborn sepsis and death from serious infection, septacimea. Bacteria rapidly colonizes the moist cord stump and has direct access to the bloodstream. In addition, bacteria colonization may lead to cord infection (omphalitis) with potential spread to the surrounding tissues and bloodstream.
Antiseptic with a broad spectrum of activity against gram negative and gram positive bacteria. There is a 40 yr history of CHX usage to the umbilical cord in developed countries, as well as widespread experience using CHX as a pre-surgical and an oral antiseptic. The safety record has been well established, in adults as well as new borns. A concentration of 4% was selected to be sufficiently potent as an antiseptic, but at a low enough concentration to ensure safe CHX levels in the blood. A group of researchers from the Hopkins School of Public Health carried out three major randomized control trials in three countries: Bangladesh, Nepal, and Pakistan. The Nepal study had two groups: one that just practiced dry cord care, another that used a whole tube of CHX once on the first day, and then followed dry cord care. Results showed that the CHX group had neonatal mortality reductions of 24% and severe omphalitis by 75%, when compared to the dry care group. A second comparison group, which used soap and water, had no difference in mortality compared to the dry cord care.
Nn deaths constitute 72% of all infant deaths, and 61% under five deaths, so there was a real need to focus on interventions to reduce nn deaths. After seeing the results from the Mullany Hopkins study, the DoH endorsed the implementation of a pilot CHX program in four districts: Banke, Bajhang, Jumla, and Parsa; Parsa study implemented by Plan Nepal and funded by USAID; other three districts managed under Nepal Family Health Program-II
Distribution of CHX by FCHVs to pregnant women at 8 months of pregnancy during the PWG monthly meeting after health education on importance of CHX Impact of meetings and FCHV involvement seen in results: 97% used CHX correctly; 75% received it from FCHVs.
CHX was supplied in a tube marketed under the brand name “Kawach”, which means a protecting device/armor against the attack by enemies during the war in ancient Nepal; that the entire tube should be used on the umbilicus stump immediately after cord cutting and then kept dry and clean
Illiteracy
98% of RDWs were immunized against tetanus toxoid and 78% had taken iron/folic acid tablets; Systematic random sampling design identified 38 recently delivered women (RDW) in each of 13 supervision areas (total 494); More than 60% had been delivered by a health professional or SBA; In 82.7% of cases, the RDWs said that the newborns’ umbilical cord was cut with sterile instruments from a clean delivery kit; compliance here means application of an entire tube of CHX at oncem in the cord stump and its surrounding areas, within 2 hours of childbirth/cutting the cord;
NEWWWWWW
Behaviour change isn’t just adding a new intervention or approach, but also about removing old practices and breaking harmful habits