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Plan International
  Bhagawan Das Shreshta, Harpreet Anand, Vidya Sampath
  May 2, 2012 – Core Group Spring Meeting


02 May
  2012                    1
   What does the Science tell us?

   What did the Nepal Government want to do?

   What was Plan International’s role in this?

   What are the policy implications and next
    steps?


Promising Futures,
Community by Community


                                        05/07/12   2
   Recently-cut cord is common portal of entry
    for bacteria

   Causes newborn sepsis and death from serious
    infection

   Bacteria can enter bloodstream




Promising Futures,
Community by Community


                                       05/07/12    3
   4% CHX ointment reduces:
    - severe cord infection (by 65%)
  - neonatal mortality (by 23.5%; 34% if          applied on
    day of delivery)
    - incidence of severe infection of umbilicus
    stump (by 70 - 80%)

                          [source: Mullany et. al, 2006]

Promising Futures,
Community by Community


                                                               4
   Current neonatal mortality rate: 33 deaths per
    1000 live births/23,000 neonatal deaths every
    year;

   72% of infant deaths; 61% of U5 deaths;

   Umbilical cord infection is about 62% of local
    bacterial infection;

   Pilot CHX programs in four districts: Banke,
    Bajhang, Jumla, and Parsa.
Promising Futures,
Community by Community


                                              05/07/12   5
   Global organization, established in 1937, that
    works side by side with communities in 50
    developing countries to end the cycle of
    poverty for children;

 In Nepal since 1978
 15 districts
 2 million people
 Four CSHGP grants

  (1997 – 2011)
Promising Futures,
Community by Community


                                                     6
   “Local Innovation for Better Outcomes for
    Neonates” (2006-2011);

   Key factors for success: Pregnant Women’s
    Groups (PWGs), facilitated by Female
    Community Health Volunteers (FCHVs);

   10-12 pregnant women in each group,
    facilitated by 1 FCHV;

Promising Futures,
Community by Community


                                                7
Promising Futures,
Community by Community


                         05/07/12   8
   FCHV role:
-   Motivate women to utilize MCH services;
-   Distribute pre-natal medicines;
-   Present at childbirth and immediate care of
    neonate;
-   Home visits after birth (1st, 3rd, 7th & 29th
    days);
-   Diagnoses and Referrals.


Promising Futures,
Community by Community


                                       05/07/12     9
Promising Futures,
Community by Community


                         05/07/12   10
   Measure the coverage and compliance in the
    application of CHX at the community level;

   CHX supplied in a tube marketed under the
    brand name “Kawach”;

   Participants were informed on proper usage.




Promising Futures,
Community by Community


                                      05/07/12    11
Promising Futures,
Community by Community


                         05/07/12   12
   Coverage rate: 82.7% of newborns had CHX
    applied to their umbilical cord;

   Compliance rate: 66.4% (of above) applied
    CHX correctly;

   97% used full tube of CHX; 2% partial tube.




Promising Futures,
Community by Community


                                       05/07/12   13
Promising Futures,
Community by Community


                         05/07/12   14
Promising Futures,
Community by Community


                         05/07/12   15
Promising Futures,
Community by Community


                         05/07/12   16
   Women who belong to PWGs were 1.3 times more
    likely to have correctly applied CHX, than those
    who were not;

   None of the women in PWGs reported using
    harmful substances on stump, as per usual local
    practice, such as cow dung, oil, or turmeric




Promising Futures,
Community by Community


                                          05/07/12     17
   Plan Nepal, through its organizational funds,
    continues the CHX program by integrating it with
    Community Based Newborn Care Program
    (CBNCP) in Rautahat district;

   As of April 30, 2012:
     - 8 districts completed CHX integration with CBNCP
     - 7 districts ongoing
     - Planning has commenced to add on 5 more
     - By June 2013, total CHX coverage goal: 45 out of 75
       districts in Nepal.

Promising Futures,
Community by Community


                                                 05/07/12    18
   The 4% CHX lotion is listed in the essential drugs
    list of Ministry of Health and Population of Nepal;

   CHX lotion is free of cost;

   CHX will be scaled up and integrated with CBNCP
    all over Nepal

   The CBNCP training manual and reporting formats
    have been revised to include CHX components.


Promising Futures,
Community by Community


                                             05/07/12     19
   WHO recommendation: “dry cord care is
    general recommendation, but when adequate
    hygiene cannot be assured in household
    environment, CHX should be used”;

   USAID brief: “there is sufficient evidence to
    recommend introduction of 4% chx cord
    cleansing, in place of dry cord care, as a
    strategy to reduce neonatal mortality in
    settings of high neonatal mortality and poor
    hygiene”
Promising Futures,
Community by Community


                                        05/07/12    20
   CHX Working Group:
    http://www.healthynewbornnetwork.org/topic/chlorhexidine


   USAID Technical Brief:     www.usaid
    .gov/our_work/global_health/mch/.../chx_issuebrief.pdf


   Johns Hopkins page on CHX:
    http://www.jhsph.edu/publichealthnews/press_releases/2012/baqui_cord




Promising Futures,
Community by Community


                                                    05/07/12        21
02 May
  2012   22

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CSHGP Special Studies in Nepal and Ethiopia_Sampath_Gannon_5.2.12

  • 1. Plan International Bhagawan Das Shreshta, Harpreet Anand, Vidya Sampath May 2, 2012 – Core Group Spring Meeting 02 May 2012 1
  • 2. What does the Science tell us?  What did the Nepal Government want to do?  What was Plan International’s role in this?  What are the policy implications and next steps? Promising Futures, Community by Community 05/07/12 2
  • 3. Recently-cut cord is common portal of entry for bacteria  Causes newborn sepsis and death from serious infection  Bacteria can enter bloodstream Promising Futures, Community by Community 05/07/12 3
  • 4. 4% CHX ointment reduces: - severe cord infection (by 65%)   - neonatal mortality (by 23.5%; 34% if applied on day of delivery) - incidence of severe infection of umbilicus stump (by 70 - 80%) [source: Mullany et. al, 2006] Promising Futures, Community by Community 4
  • 5. Current neonatal mortality rate: 33 deaths per 1000 live births/23,000 neonatal deaths every year;  72% of infant deaths; 61% of U5 deaths;  Umbilical cord infection is about 62% of local bacterial infection;  Pilot CHX programs in four districts: Banke, Bajhang, Jumla, and Parsa. Promising Futures, Community by Community 05/07/12 5
  • 6. Global organization, established in 1937, that works side by side with communities in 50 developing countries to end the cycle of poverty for children;  In Nepal since 1978  15 districts  2 million people  Four CSHGP grants (1997 – 2011) Promising Futures, Community by Community 6
  • 7. “Local Innovation for Better Outcomes for Neonates” (2006-2011);  Key factors for success: Pregnant Women’s Groups (PWGs), facilitated by Female Community Health Volunteers (FCHVs);  10-12 pregnant women in each group, facilitated by 1 FCHV; Promising Futures, Community by Community 7
  • 8. Promising Futures, Community by Community 05/07/12 8
  • 9. FCHV role: - Motivate women to utilize MCH services; - Distribute pre-natal medicines; - Present at childbirth and immediate care of neonate; - Home visits after birth (1st, 3rd, 7th & 29th days); - Diagnoses and Referrals. Promising Futures, Community by Community 05/07/12 9
  • 10. Promising Futures, Community by Community 05/07/12 10
  • 11. Measure the coverage and compliance in the application of CHX at the community level;  CHX supplied in a tube marketed under the brand name “Kawach”;  Participants were informed on proper usage. Promising Futures, Community by Community 05/07/12 11
  • 12. Promising Futures, Community by Community 05/07/12 12
  • 13. Coverage rate: 82.7% of newborns had CHX applied to their umbilical cord;  Compliance rate: 66.4% (of above) applied CHX correctly;  97% used full tube of CHX; 2% partial tube. Promising Futures, Community by Community 05/07/12 13
  • 14. Promising Futures, Community by Community 05/07/12 14
  • 15. Promising Futures, Community by Community 05/07/12 15
  • 16. Promising Futures, Community by Community 05/07/12 16
  • 17. Women who belong to PWGs were 1.3 times more likely to have correctly applied CHX, than those who were not;  None of the women in PWGs reported using harmful substances on stump, as per usual local practice, such as cow dung, oil, or turmeric Promising Futures, Community by Community 05/07/12 17
  • 18. Plan Nepal, through its organizational funds, continues the CHX program by integrating it with Community Based Newborn Care Program (CBNCP) in Rautahat district;  As of April 30, 2012: - 8 districts completed CHX integration with CBNCP - 7 districts ongoing - Planning has commenced to add on 5 more - By June 2013, total CHX coverage goal: 45 out of 75 districts in Nepal. Promising Futures, Community by Community 05/07/12 18
  • 19. The 4% CHX lotion is listed in the essential drugs list of Ministry of Health and Population of Nepal;  CHX lotion is free of cost;  CHX will be scaled up and integrated with CBNCP all over Nepal  The CBNCP training manual and reporting formats have been revised to include CHX components. Promising Futures, Community by Community 05/07/12 19
  • 20. WHO recommendation: “dry cord care is general recommendation, but when adequate hygiene cannot be assured in household environment, CHX should be used”;  USAID brief: “there is sufficient evidence to recommend introduction of 4% chx cord cleansing, in place of dry cord care, as a strategy to reduce neonatal mortality in settings of high neonatal mortality and poor hygiene” Promising Futures, Community by Community 05/07/12 20
  • 21. CHX Working Group: http://www.healthynewbornnetwork.org/topic/chlorhexidine  USAID Technical Brief: www.usaid .gov/our_work/global_health/mch/.../chx_issuebrief.pdf  Johns Hopkins page on CHX: http://www.jhsph.edu/publichealthnews/press_releases/2012/baqui_cord Promising Futures, Community by Community 05/07/12 21
  • 22. 02 May 2012 22

Notes de l'éditeur

  1. Recently-cut cord is a common portal of entry for invasive bacteria that cause newborn sepsis and death from serious infection, septacimea. Bacteria rapidly colonizes the moist cord stump and has direct access to the bloodstream. In addition, bacteria colonization may lead to cord infection (omphalitis) with potential spread to the surrounding tissues and bloodstream.
  2. Antiseptic with a broad spectrum of activity against gram negative and gram positive bacteria. There is a 40 yr history of CHX usage to the umbilical cord in developed countries, as well as widespread experience using CHX as a pre-surgical and an oral antiseptic. The safety record has been well established, in adults as well as new borns. A concentration of 4% was selected to be sufficiently potent as an antiseptic, but at a low enough concentration to ensure safe CHX levels in the blood. A group of researchers from the Hopkins School of Public Health carried out three major randomized control trials in three countries: Bangladesh, Nepal, and Pakistan. The Nepal study had two groups: one that just practiced dry cord care, another that used a whole tube of CHX once on the first day, and then followed dry cord care. Results showed that the CHX group had neonatal mortality reductions of 24% and severe omphalitis by 75%, when compared to the dry care group. A second comparison group, which used soap and water, had no difference in mortality compared to the dry cord care.
  3. Nn deaths constitute 72% of all infant deaths, and 61% under five deaths, so there was a real need to focus on interventions to reduce nn deaths. After seeing the results from the Mullany Hopkins study, the DoH endorsed the implementation of a pilot CHX program in four districts: Banke, Bajhang, Jumla, and Parsa; Parsa study implemented by Plan Nepal and funded by USAID; other three districts managed under Nepal Family Health Program-II
  4. Distribution of CHX by FCHVs to pregnant women at 8 months of pregnancy during the PWG monthly meeting after health education on importance of CHX Impact of meetings and FCHV involvement seen in results: 97% used CHX correctly; 75% received it from FCHVs.
  5. CHX was supplied in a tube marketed under the brand name “Kawach”, which means a protecting device/armor against the attack by enemies during the war in ancient Nepal; that the entire tube should be used on the umbilicus stump immediately after cord cutting and then kept dry and clean
  6. Illiteracy
  7. 98% of RDWs were immunized against tetanus toxoid and 78% had taken iron/folic acid tablets; Systematic random sampling design identified 38 recently delivered women (RDW) in each of 13 supervision areas (total 494); More than 60% had been delivered by a health professional or SBA; In 82.7% of cases, the RDWs said that the newborns’ umbilical cord was cut with sterile instruments from a clean delivery kit; compliance here means application of an entire tube of CHX at oncem in the cord stump and its surrounding areas, within 2 hours of childbirth/cutting the cord;
  8. NEWWWWWW
  9. Behaviour change isn’t just adding a new intervention or approach, but also about removing old practices and breaking harmful habits
  10. NEWWWWWWWWWWWWWWW
  11. NEWWWWW – add to title Dec 2011
  12. conclusions/what next –