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BREAST INFECTIONS
BREAST INFECTION


                                                               NON_LACTATING
   LACTATING BREAST                                               BREAST



    ACUTE
                      ABSCESS
  BACTERIAL
   MASTITIS




  PERIDUCTAL MASTITIS
with/without PERIAREOLAR
         ABSCESS                                       FUNGAL-
                                                   Actinomycosis of
                                                        breast
                                                                      SUPERFICIAL
                        TB OF BREAST
                                                                         BREAST
                                                                       INFECTION
LACTATING BREAST
CRITERIA       PRESENTATION            INV.   MANAGEMENT
                     LACTATING BREAST
BREAST
INFECTION
ACUTE BACTERIAL                                  1. Effective
MASTITIS/         • signs of acute               Milk removal
LACTATIONAL       inflammation                   -proper breast
MASTITIS          • 74% to 95% of cases          feeding method
                  occur in the first 12          -Encourage
• milk stasis     weeks                          Frequent
                                                 breastfeeding
• infections                                     -express breastmilk
                                                 by hand towards nipple /
•Staphylococcus                                  Heat therapy till milk
Aureus                                            flows
(from infant
, ascending
infection )
2. Antibiotic therapy
- symptoms severe
-a nipple fissure Is visible
-symptoms do not improve after 12-24
hours of improved milk removal
ORAL
• dicloxacillin, 250 mg qid

•amoxicillin–clavulanic acid, 875 mg bd

• a first-generation cephalosporin
cephalexin, 500 mg qid

•methicillin-resistant S. aureus (MRSA) may
necessitate the use of trimethoprim-
sulfamethoxazole, 160/800 mg bd 7 days

•clindamycin, or tetracycline depending on
the patient's history of infections and the
local prevalence of MSRA

3. Symptomatic Treatment
-analgesia : diclofenac 50 mg tds
-antipyretic : paracetamol 1g bd
CRITERIA   PRESENTATION         INV.                  MANAGEMENT

BREAST
INFECTION
BREAST        •fever               •FBC                1. Admitted to ward
ABSCESS       •Malaise                                     (General indications for
              •Breast tenderness   •CRP                    admission -obvious sepsis or
              •Swelling and                                hemodynamic compromise,
              erythema             •Diagnostic needle      immunocompromise
              •Decreased milk      aspiration drainage     (diabetes), rapid & progressive
              flow                 ,USS guided–            infection, and failure of
              •Nipple discharge    pus?cytology, pus      outpatient antibiotic therapy)
                                   C&S
                                                       2. Supportive measures:
                                   •Milk leucocyte     •Fluid –
                                   count/bacterial     •analgesia : diclofenac 50 mg tds
                                   quantification,     •antipyretic : paracetamol 1g bd
                                   C&S

                                   •Blood C & S          3. Effective milk removal
                                                         • breastfeeding
                                   • Diagnostic breast   • pump
                                   USS/MMG               • heat therapy
4. Antibiotics (oral/IV)10-14 days

                                     •dicloxacillin : 500 mg orally four times daily
                                     •cephalexin : 500 mg orally three times daily
                                     •doxycycline : 100 mg orally twice daily
                                     •clindamycin : 300-450 mg orally four times
                                     daily

                                     ORAL:
                                     •dicloxacillin : 500 mg qid
                                     •cephalexin : 500 mg orally tds
                                     •doxycycline : 100 mg orally bd
                                     •clindamycin : 300-450 mg qid

                                     IV :
                                     •oxacillin : 1-2 g intravenously every 4-6
Breast abscess presents as a         hours
hypoechoic fluid collection in       •nafcillin : 1-2 g intravenously every 4-6 hours
the tissue with the absence of       •cefazolin : 1-2 g intravenously every 8 hours
vascular signals.
6. Surgery

•18- to 19 gauge needle             -repeated aspirations under AB +/- US
•daily aspiration for 5 to 7 days   guidandance
• followed by ultrasound (+/-)      -I & D + biopsy of abscess wallHPE

                                    7. Supportive counselling
                                    -breastfeeding
  •incision and drainage            -encouragement
  aspiration fails or large
  abscesses (>5 cm in diameter)     8. oral AB continued for 10 days post-op

                                    9. TCA 1/52

                                    10.once infection resolves MMG/ USS
NON-LACTATING BREAST INFECTION
CRITERIA   PRESENTATION           INV.        MANAGEMENT
BREAST
INFECTION`
Periductal     -nipple discharge,     (SAME AS    1. Admitted to ward
mastitis/      subareolar mass/       LACTATING
subareolar     abscess, mammary       )           2. Supportive measures:
abscess        duct fistula, nipple   +:          •Fluid
               retraction, repeated               •analgesia : diclofenac 50 mg tds
ass. with     incidence              •RBS        •antipyretic : paracetamol 1g bd
duct ectasia                          •AFB
                                                  3. Antibiotics
                                                  -metronidazole 400mg tds

                                                  5. Surgery
                                                  •repeated aspirations under AB +/- US
                                                  guidandance
                                                  •I & D + biopsy of abscess wallHPE
                                                  once acute phase resolves: Hadfield's
                                                  operation

                                                  6. oral AB continued for 10 days post-op

                                                  7. TCA 1/52,once infection resolves
                                                  MMG/ USS
MAMMARY DUCT FISTULA




                       RETROAREOLA ABSCESS: ILL-DEFINED, NONCALCIFIED
                       MASSES HIGH-DENSITY, ILL-DEFINED HETEROGENEOUS
                       MASS WITH AN IRREGULAR MARGIN.
CRITERIA      PRESENTATION          INV.          MANAGEMENT
BREAST
INFECTION`
TB of breasts     -slow growing         •FBC          1. Admitted to ward
-nodular,         -painless mass        •MANTOUX
diffuse,          -tubucle ulcer        TEST          2. Supportive measures:
sclerosing        -multiple sinuses     •CRP          Fluid
types             -pulmonary/other tb   •CHEST X-     analgesia : diclofenac 50 mg tds
                  sites                 RAY
• nodular form :                        •Breast USS   3. Anti-TB regime
•either hypoechoic with ill-            •MMG          6 months of anti-TB therapy
defined margins or                      •FNAC         •2 months with a 4-drug combination
complex cystic masses                                 (ethambutol, rifampin, isoniazid, and
                                        •Culture      pyrazinamide)
• diffuse:                                            • 4 months with a 2-drug combination
ill-defined hypoechoic masses                         (isoniazid and rifampin)
                                                      -low response,draining fistula: surgical
• sclerosing breast tb:                               interventiondraining cold abscess or
increased echogenecity of the                         mastectomy with/without axillary
breast parenchyma often with                          clearance
no definite mass is seen
Breast infections

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Breast infections

  • 2. BREAST INFECTION NON_LACTATING LACTATING BREAST BREAST ACUTE ABSCESS BACTERIAL MASTITIS PERIDUCTAL MASTITIS with/without PERIAREOLAR ABSCESS FUNGAL- Actinomycosis of breast SUPERFICIAL TB OF BREAST BREAST INFECTION
  • 4. CRITERIA PRESENTATION INV. MANAGEMENT LACTATING BREAST BREAST INFECTION ACUTE BACTERIAL 1. Effective MASTITIS/ • signs of acute Milk removal LACTATIONAL inflammation -proper breast MASTITIS • 74% to 95% of cases feeding method occur in the first 12 -Encourage • milk stasis weeks Frequent breastfeeding • infections -express breastmilk by hand towards nipple / •Staphylococcus Heat therapy till milk Aureus flows (from infant , ascending infection )
  • 5. 2. Antibiotic therapy - symptoms severe -a nipple fissure Is visible -symptoms do not improve after 12-24 hours of improved milk removal ORAL • dicloxacillin, 250 mg qid •amoxicillin–clavulanic acid, 875 mg bd • a first-generation cephalosporin cephalexin, 500 mg qid •methicillin-resistant S. aureus (MRSA) may necessitate the use of trimethoprim- sulfamethoxazole, 160/800 mg bd 7 days •clindamycin, or tetracycline depending on the patient's history of infections and the local prevalence of MSRA 3. Symptomatic Treatment -analgesia : diclofenac 50 mg tds -antipyretic : paracetamol 1g bd
  • 6. CRITERIA PRESENTATION INV. MANAGEMENT BREAST INFECTION BREAST •fever •FBC 1. Admitted to ward ABSCESS •Malaise (General indications for •Breast tenderness •CRP admission -obvious sepsis or •Swelling and hemodynamic compromise, erythema •Diagnostic needle immunocompromise •Decreased milk aspiration drainage (diabetes), rapid & progressive flow ,USS guided– infection, and failure of •Nipple discharge pus?cytology, pus outpatient antibiotic therapy) C&S 2. Supportive measures: •Milk leucocyte •Fluid – count/bacterial •analgesia : diclofenac 50 mg tds quantification, •antipyretic : paracetamol 1g bd C&S •Blood C & S 3. Effective milk removal • breastfeeding • Diagnostic breast • pump USS/MMG • heat therapy
  • 7. 4. Antibiotics (oral/IV)10-14 days •dicloxacillin : 500 mg orally four times daily •cephalexin : 500 mg orally three times daily •doxycycline : 100 mg orally twice daily •clindamycin : 300-450 mg orally four times daily ORAL: •dicloxacillin : 500 mg qid •cephalexin : 500 mg orally tds •doxycycline : 100 mg orally bd •clindamycin : 300-450 mg qid IV : •oxacillin : 1-2 g intravenously every 4-6 Breast abscess presents as a hours hypoechoic fluid collection in •nafcillin : 1-2 g intravenously every 4-6 hours the tissue with the absence of •cefazolin : 1-2 g intravenously every 8 hours vascular signals.
  • 8. 6. Surgery •18- to 19 gauge needle -repeated aspirations under AB +/- US •daily aspiration for 5 to 7 days guidandance • followed by ultrasound (+/-) -I & D + biopsy of abscess wallHPE 7. Supportive counselling -breastfeeding •incision and drainage -encouragement aspiration fails or large abscesses (>5 cm in diameter) 8. oral AB continued for 10 days post-op 9. TCA 1/52 10.once infection resolves MMG/ USS
  • 10. CRITERIA PRESENTATION INV. MANAGEMENT BREAST INFECTION` Periductal -nipple discharge, (SAME AS 1. Admitted to ward mastitis/ subareolar mass/ LACTATING subareolar abscess, mammary ) 2. Supportive measures: abscess duct fistula, nipple +: •Fluid retraction, repeated •analgesia : diclofenac 50 mg tds ass. with incidence •RBS •antipyretic : paracetamol 1g bd duct ectasia •AFB 3. Antibiotics -metronidazole 400mg tds 5. Surgery •repeated aspirations under AB +/- US guidandance •I & D + biopsy of abscess wallHPE once acute phase resolves: Hadfield's operation 6. oral AB continued for 10 days post-op 7. TCA 1/52,once infection resolves MMG/ USS
  • 11. MAMMARY DUCT FISTULA RETROAREOLA ABSCESS: ILL-DEFINED, NONCALCIFIED MASSES HIGH-DENSITY, ILL-DEFINED HETEROGENEOUS MASS WITH AN IRREGULAR MARGIN.
  • 12. CRITERIA PRESENTATION INV. MANAGEMENT BREAST INFECTION` TB of breasts -slow growing •FBC 1. Admitted to ward -nodular, -painless mass •MANTOUX diffuse, -tubucle ulcer TEST 2. Supportive measures: sclerosing -multiple sinuses •CRP Fluid types -pulmonary/other tb •CHEST X- analgesia : diclofenac 50 mg tds sites RAY • nodular form : •Breast USS 3. Anti-TB regime •either hypoechoic with ill- •MMG 6 months of anti-TB therapy defined margins or •FNAC •2 months with a 4-drug combination complex cystic masses (ethambutol, rifampin, isoniazid, and •Culture pyrazinamide) • diffuse: • 4 months with a 2-drug combination ill-defined hypoechoic masses (isoniazid and rifampin) -low response,draining fistula: surgical • sclerosing breast tb: interventiondraining cold abscess or increased echogenecity of the mastectomy with/without axillary breast parenchyma often with clearance no definite mass is seen