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Presentation on
Genes for rRNA and RP
by Md. A.R. Apu
rRNA and
Ribosome
rRNAs as ribosomal 1
RPL15RPL3 gene
RP genes
2
29737k 29739k29738k 29740k
3LHET
239ok 2400k
RPL18 RPL21
RP genes
3L
723ok 724ok
CG1 4026 BHD NEOS Nei-p22 MED4
3L
2224ok 2225ok
CG1 4026
Tif1i
CR43765
3
rRNA
genes
In prokaryotes In eukaryotes 4
Genes are organized in a tandemly repeated units
18s rRNA
Pol 1 5.8s
rRNA
Help in Ribosome
translocation
Used inEvolutionary
study
Phylogenetic study
Location: 21p11.2
Location: 21p11.2
5.8s rRNA
rRNA genes, rRNAs and
functions
5
rRNA genes, rRNAs and
functions
5s rRNA
Location: 21p11.2 - HUMRGMB
Molecular analysis
Phylogenetic tree construction
28s
Location: 1q42.43 – X51545
Function has not cleared yet
Help in tRNA binding
6
23s rRNA
Locus – AJ605115
16s rRNA
Locus – AJ549508
830bp
Drug targets to inhibit translation
rRNA genes, rRNAs and
functions
7
Scaffolding role
SDS
1.Finely Orchestrated Movements: Evolution of the Ribosomal RNA Genes
Thomas H. Eickbush and Danna G. Eickbush
GENETICS February 1, 2007 vol. 175 no. 2 477-485;https://doi.org/10.1534/genetics.107.071399
2.NCBI
3.Hugo Gene Nomenclature Committee
References
8
Thank You
Questions?

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rRNA genes and Ribosomal protein genes