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The Internet of Antibodies
Jonathan Milner
Founder & CEO of Abcam plc
Introduction
• Jonathan Milner, Founder & CEO
• Former lifescience research scientist – studied breast cancer genes at Cambridge university
• Very exciting time at the start of a golden age of biological research
• Unable to buy the reagents needed to conduct gene studies
• Founded Abcam in 1998 to sell these reagents – antibodies – from an online catalogue
• Vision to create the largest catalogue of the best antibodies in the world
• Acquisitions have broadened Abcam into a world leader in protein research tools

2
Abcam in numbers
Sales

Pre-tax profits

Market cap

£122m

£46.5m

c£1bn

(year to 30 June 2013)

(year to 30 June 2013)

(£58m at IPO in 2005)

Web pages in Google

Publications
referencing Abcam
products in 2012

Delivering to

index

1.75m

(source: Google Search)

c24k

(source: Google Scholar)

Number of products

c125,000

>100

countries worldwide

3
What we do
• Manufacture, source and sell protein research tools including antibodies
– Tens of thousands of proteins interact in millions of ways
• Antibodies enable research – picks and shovels for studying proteins at a cellular level
• Used in scientific breakthroughs leading to new treatments for diseases such as cancer
• International customer base – academia to global pharma
• The US is Abcam’s largest market – huge US investment in lab bench research
• Competitors include Life Technologies, Merck Millipore, Santa Cruz Biotechnology

4
The internet of antibodies
• Historically, laboratory reagents were sold from paper catalogues
– Limited quantity and timeliness of information , minimal customer interaction
• The internet meant product information could be hosted online
• Potential for huge quantities of relevant, continually updated information
• This information is open source and unique to Abcam products
• Dynamic relationship created with online community of scientists
• Products manufactured in-house or sourced from third parties and branded Abcam

5
The information flywheel
• The quicker product information is
added, the faster sales grow
• More sales lead to an increased rate of
information addition
• This leads to improved sales and better
pricing
• Ultimately this makes the business highly
defensible

6
Catalogue growth by product over time
130,000

Number of products on the Abcam calalogue over time

120,000
110,000
100,000
90,000
80,000
70,000
60,000
50,000
40,000
30,000
20,000
10,000
0
H1

H2

2001/02

H1

H2

2002/03

H1

H2

2003/04

OEM Primary Antibodies

H1

H2

2004/05

H1

H2

2005/06

OEM Other Products

H1

H2

2006/07

H1

H2

2007/08

H1

H2

2008/09

Abcam Primary Antibodies

H1

H2

2009/10

H1

H2

2010/11

H1

H2

2011/12

Abcam Other Products

H1

H2

2012/13
Sales momentum in the catalogue
including unaudited pre-acquisition revenues of Epitomics (reagents) and Ascent

60000

Revenue £k calculated at fixed exchange rates

50000

40000

30000

20000

10000

0
H1

H2

2002 / 03

H1

H2

2003 / 04

H1

H2

2004 / 05

H1

H2

2005 / 06

H1

H2

2006 / 07

H1

H2

2007 / 08

H1

H2

2008 / 09

H1

H2

2009 / 10

H1

H2

2010 / 11

H1

H2

2011/12

H1

H2

2012/13

Added pre 2002 / 03

Added in 2002 / 03

Added in 2003 / 04

Added in 2004 / 05

Added in 2005 / 06

Added in 2006 / 07

Added in 2007 / 08

Added in 2008 / 09

Added in 2009 / 10

Added in 2010 / 11

Added in 2011 / 12

Added in 2012 / 13
Continual improvement
• Our website is an ever more important tool for our business
• IT team continues to focus on uptime and responsiveness
– 99.99% uptime on our website
– Response time of < 2 seconds for searches
• Improving accessibility and functionality of the front-end website
• Re-engineering core systems to enhance scalability
• Customer surveys, customer focus groups and randomly sampling web visitors

9
How big can it get?
• Business model designed for scalability
• High growth market fuelled by scientific advances
• Recent acquisition of a US company, Epitomics, with exciting new technology
• Vision to create the world’s leading lifescience reagents company

www.abcam.com

10

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abcam - NOAH13 London

  • 1. The Internet of Antibodies Jonathan Milner Founder & CEO of Abcam plc
  • 2. Introduction • Jonathan Milner, Founder & CEO • Former lifescience research scientist – studied breast cancer genes at Cambridge university • Very exciting time at the start of a golden age of biological research • Unable to buy the reagents needed to conduct gene studies • Founded Abcam in 1998 to sell these reagents – antibodies – from an online catalogue • Vision to create the largest catalogue of the best antibodies in the world • Acquisitions have broadened Abcam into a world leader in protein research tools 2
  • 3. Abcam in numbers Sales Pre-tax profits Market cap £122m £46.5m c£1bn (year to 30 June 2013) (year to 30 June 2013) (£58m at IPO in 2005) Web pages in Google Publications referencing Abcam products in 2012 Delivering to index 1.75m (source: Google Search) c24k (source: Google Scholar) Number of products c125,000 >100 countries worldwide 3
  • 4. What we do • Manufacture, source and sell protein research tools including antibodies – Tens of thousands of proteins interact in millions of ways • Antibodies enable research – picks and shovels for studying proteins at a cellular level • Used in scientific breakthroughs leading to new treatments for diseases such as cancer • International customer base – academia to global pharma • The US is Abcam’s largest market – huge US investment in lab bench research • Competitors include Life Technologies, Merck Millipore, Santa Cruz Biotechnology 4
  • 5. The internet of antibodies • Historically, laboratory reagents were sold from paper catalogues – Limited quantity and timeliness of information , minimal customer interaction • The internet meant product information could be hosted online • Potential for huge quantities of relevant, continually updated information • This information is open source and unique to Abcam products • Dynamic relationship created with online community of scientists • Products manufactured in-house or sourced from third parties and branded Abcam 5
  • 6. The information flywheel • The quicker product information is added, the faster sales grow • More sales lead to an increased rate of information addition • This leads to improved sales and better pricing • Ultimately this makes the business highly defensible 6
  • 7. Catalogue growth by product over time 130,000 Number of products on the Abcam calalogue over time 120,000 110,000 100,000 90,000 80,000 70,000 60,000 50,000 40,000 30,000 20,000 10,000 0 H1 H2 2001/02 H1 H2 2002/03 H1 H2 2003/04 OEM Primary Antibodies H1 H2 2004/05 H1 H2 2005/06 OEM Other Products H1 H2 2006/07 H1 H2 2007/08 H1 H2 2008/09 Abcam Primary Antibodies H1 H2 2009/10 H1 H2 2010/11 H1 H2 2011/12 Abcam Other Products H1 H2 2012/13
  • 8. Sales momentum in the catalogue including unaudited pre-acquisition revenues of Epitomics (reagents) and Ascent 60000 Revenue £k calculated at fixed exchange rates 50000 40000 30000 20000 10000 0 H1 H2 2002 / 03 H1 H2 2003 / 04 H1 H2 2004 / 05 H1 H2 2005 / 06 H1 H2 2006 / 07 H1 H2 2007 / 08 H1 H2 2008 / 09 H1 H2 2009 / 10 H1 H2 2010 / 11 H1 H2 2011/12 H1 H2 2012/13 Added pre 2002 / 03 Added in 2002 / 03 Added in 2003 / 04 Added in 2004 / 05 Added in 2005 / 06 Added in 2006 / 07 Added in 2007 / 08 Added in 2008 / 09 Added in 2009 / 10 Added in 2010 / 11 Added in 2011 / 12 Added in 2012 / 13
  • 9. Continual improvement • Our website is an ever more important tool for our business • IT team continues to focus on uptime and responsiveness – 99.99% uptime on our website – Response time of < 2 seconds for searches • Improving accessibility and functionality of the front-end website • Re-engineering core systems to enhance scalability • Customer surveys, customer focus groups and randomly sampling web visitors 9
  • 10. How big can it get? • Business model designed for scalability • High growth market fuelled by scientific advances • Recent acquisition of a US company, Epitomics, with exciting new technology • Vision to create the world’s leading lifescience reagents company www.abcam.com 10