Digital Health & Wellness: Company Presentation by Rainer Kasan, Co-Founder & CTO of Telepaxx at the NOAH Conference 2018 in London, Old Billingsgate 30-31 October 2018.

1. Tuesday, 30th October 2018
Rainer Kasan, Founder and CTO
From Medical Archiving
to the Leader in Health Cloud Services

2. Three Conferences, One Mission: Empower the European Digital Ecosystem
To provide a physical marketplace
that facilitates funding of
digital European companies
at all stages
Mission Mission Mission
To promote Israel - European
relationships and enable funding
To bring together future-shaping
executives and investors active
across segments driven
by digital revolution
Connecting
Capital with
Entrepreneurs
Connecting European
Champions
and Challengers
Connecting Israel’s Startups
with Large Corporates
and Investors
30-31 October 2019
Old Billingsgate, London
13-14 June 2019
STATION Berlin
9-10 April 2019
Hangar 11, Tel Aviv

3. 2
Location: Nuremberg, Germany (incl. data centers in South & North)
History: >20 years of experience in medical image archiving and processing
Standards & Certifications: DICOM, HL 7 Standard; German Data Privacy &
Protection Seal, European Privacy Seal
Management & Ownership: 100% privately owned
Medical Data Analyzing:
Deep Learning & SaaS
Company
Products
Market
Telepaxx Company Profile:
Experts in Archiving, Sharing and Analyzing of Medical Data
Archiving of Medical Images & Documents
High Security Sharing of Medical Data
600 hospitals and radiologies in
Germany
13 billion medical images
Per day +3 million new medical images
15 million patients per year
CEO
Andreas Dobler
CTO
Rainer Kasan
(Founder)
Chairman
Herbert Grau
(Founder)
"We are the market leader for medical image
archiving and sharing in Germany and Europe!"

4. 3
Telepaxx:
Market & Regulatory Framework for Medical Data
✓ 100,000,000 diagnostic imaging examinations
have been conducted in Europe in 2016. Every
examination can contain hundreds of single images
✓ Hospital data is growing by up to 30 % every year.
A midsize clinic produces 4 – 6 TB / year, a university
hospital produces 40 – 100 TB / year
✓ More and more medical departments will
become digital in the near future and produce
additional billions of medical images
✓ Storing, sharing and processing of the
dramatically increasing number of medical images
must be compliant with the GDPR
✓ The GDPR increased the pressure to European
countries to react to the legal requirements
defining high standards for secure storing and
processing of sensible patients data
✓ All archived data in Telepaxx data centers are
encrypted, the encryption key is at customer site
(archiving) or owned by medical doctors or
patients (sharing)
✓ Since more than 20 years Telepaxx is compliant
with the German Personal Data Protection Law,
which was more strict than the GDPR is now
✓ The new GDPR opens significant business
opportunities for Telepaxx in Europe:
1) Expansion through GDPR compliant archiving projects
in Europe
2) GDPR defined pseudonymization (in the medical
images the patient demographic data is replaced by a
reference number).This allows data analytics (AI)
projects just with the consent of the hospital (not of
the patient any more)
Market Regulatory Framework & Growth Potential

5. 4
Business Model: Archiving Core Business
Telepaxx is the European Market Leader for Medical Image Archiving
Telepaxx Archive: Medical Archiving as a Service 2nd
and 3rd Tier data storage for medial image data
✓ GDPR compliant: Certified Data Security
Certified data protection and data security concept since more
than 20 years,
(Telepaxx has own data centers for >20 years)
✓ GDPR opens new markets in the EU
Starting business in France and Poland
✓ Vendor Neutral Archiving (VNA)
Compatibility with all PACS (Medical Imaging) providers
guaranteed,
Works for Radiology as well as for other “-ologies” like
Pathology,
Ophthalmology, Cardiology, etc.
✓ Direct access to medical workflow at customer
600 Telepaxx owned servers in clinical workflow are part of our
e-Health platform
✓ Trustful, long-term customer relationships
Standards and Certifications:
DICOM-, HL 7-, IHE-Standard;
German Data Privacy &
Protection Seal, European
Privacy Seal
Hospitals and radiologies as customers:
Largest clinic groups in Germany:
✓Asklepios
✓Helios
✓Rhön Clinics
Largest single clinics:
✓Clinic Nuremberg (2.500 beds)
✓Clinic Stuttgart (2.100 beds)
>600
Coverage Germany
(Selective)

6. 5
Radiology
HOSPITAL
Ophthalmology
Cardiology
Tier 1: PACSStorage
Level
Tasks
Activities
PACS / Modalities
Pathology
NewIndicationFields
Tier 2:
e-pacs Appliance
Unencrypted online storage, 3-5 years
Data Acquisition;
Dicom, HL 7, IHE
Create Patient
Accounts for HDS
Encryption /
Decryption
Deep
Learning
on site
Tier 3:
e-pacs Cloud Archive
VNA and tiered storage management
Security &
Encryption
Archiving
File
Sharing
Value Added
Service
Deep
Learning
central
NewApplicationAreas
Business Model: Archiving
Growth Strategy
Core

7. 6
Business Model: Archiving Growth Strategy
Telepaxx is the Fastest Growing European Market Leader for Medical Image Archiving
Growth of data volume in the Telepaxx Data Center
Images in e-pacs

8. 7
Business Model: Sharing - HealthDataSpace
Simple and secure access on medical data
Medical Images:
Any time
Any where
Any platform

9. 8
Business Model: Sharing
Telepaxx has the only certified product for sharing of medical data
Telepaxx HealthDataSpace for sharing medical data:
The secure „Dropbox“ for medical images and health
data
✓ Certified with the German Data Privacy and Protection
Seal, 100 % GDPR compliant
✓ Seamlessly integrated within clinic workflows due to
DICOM, IHE and HL7 interfaces to support clinical
process
✓ Every archived study can create automatically a patient
account with images and corresponding medical
reports
✓ Patients keep their right to informational self-
determination and share their medical records e.g. to
get a second opinion
✓ Multi-platform, running on smartphone, tablet and
desktop computers
HealthDataSpace has an actual growth rate
of 75.000 new patient accounts per month
>20
Million medical images and documents
have been shared via HealthDataSpace
$
Fee-based accounts for doctors/radiologists
and clinics
The most active medical use case a
mammography tumor board has transmitted
>1.000 cases with HealthDataSpace
Free access for patients (up to 1 GB of data
volume)
Integrated Webshop

10. 9
Business Model: Analyzing Medical Data
We build the base for deep learning / AI and provide access to the healthcare industry
BASE
Steps in developing a medical deep learning algorithm
ACCESS
▪ Identify optimal
algorithm
▪ Adjust parameters,
train algorithm,
get classifier
▪ Offer Value Added
Services to clinics,
doctors,
radiologists, etc.
▪ Test in real-life
setting
▪ CE (MDR) / FDA
Labeling
▪ Integrate in
clinical workflow
and IT
infrastructure
▪ Provide smart
data for relevant
use case
▪ Prepare training
data sample
▪ Telepaxx Data
Center: 13 PB of
medical data
(13 billion DICOM
images and medical
reports)
▪ Big data source
1
PARTNERSHIP
2 3 4
Define image
data source
Pre-process
image data
Create classifier
Medical
workflow
integration
Deliver Value
Added Services
5
“We have the largest database to enable deep learning on medical images!”
ACCESS
5
Value added
services

11. 10
Business Model: Analyzing Medical Data
We started deep learning projects for automated diagnosis
Diagnosis of Brain Bleeding, Segmentation of Vertebrae,
Mammography Screening, Prostate Screening
▪ With strong scientific partners in cognitive computing
▪ Based on Telepaxx’s smart image databases
▪ AI Classifiers installed on Telepaxx Department Servers for
clinical evaluation
Variety of use cases:
▪ Decision support
▪ Immediate alert in case of crisis
(e.g. CT → Brain Bleeding → alarm)
▪ Optimized work list sorting
▪ Automatic second diagnosis
▪ Medical research findings and analytics
Telepaxx already provides "Value Added Services" to
customers:
▪ e.g. fully automated diagnosis of "pulmonary nodule
detection in lung images" (CT) - customers pay per use or a
monthly flatrate
4 medical deep
learning projects
Use cases
Experience in Value
Added Services

12. Telepaxx
Medical Data Archiving, Sharing and Analyzing
rkasan@telepaxx.de
Telepaxx Medical Archiving GmbH
Wasserrunzel 5
D-91186 Büchenbach
www.telepaxx.de

13. Selected Completed NOAH Transactions
Focus on Leading European Internet companies
Covering over 400 companies across 25 online
verticals, a broad range of over 500 investors as
well as 100+ online-focused corporates
Deep understanding of industry dynamics
Ability to add value beyond banking advice
Facilitates overall process and minimizes
management distraction
NOAH Advisors is globally well connected
and has direct access to virtually all key
players in the industry
Knowledge of and strong relationships with
potential buyers’ key decision makers
Proactively finds and unlocks attractive
investment opportunities for leading investors
Annual NOAH Conference in its 8th year
Over 40 years of combined relevant M&A experience
Routine execution of M&A and financing transactions
with sizes of several billion euros
25+ successfully completed NOAH Advisors transactions
underline successful transfer of M&A competencies to
the Internet sector
Entrepreneurial mind-set, focused on growing the
business and establishing a reputation for excellence
Ability to deliver top results in short time frames
Highly success-based compensation structures align
interests of clients and NOAH Advisors, and demonstrate
conviction to deliver top results
Creative deal solutions
December 2014
October 2014 May 2014
Sale of 100% of
for $800m to
Exclusive Financial Advisor to
Fotolia and the Selling Shareholders
Sale of 100% of
for €80m to
Exclusive Financial Advisor to
Trovit and its Shareholders
sold 100% of
for $228m to a joint venture between
Exclusive Financial Advisor to Yad2
and its Shareholders
Unique Industry Know-How
Unmatched Network and Relationships
Strong Investment Banking Competence
Full Commitment - We Are Entrepreneurs!
EUROPE’S LEADING INTERNET
CORPORATE FINANCE BOUTIQUE
October 2016
July 2018
December 2016
®
The NOAH Advisors Core Banking Team
Investment in
Exclusive Financial Advisor to KäuferPortal
and its Shareholders
by
84% Ownership
Exclusive Financial Advisor to
PromoFarma and its shareholders
Financial Advisor to Silver Lake
Investment in
by
September 2018
August 2017
Financial Advisor to 10bis and its shareholders
Financial Advisor to EMK Capital
Acquisition of a Majority Stake in
by
at a valuation of $200m
Marco Rodzynek
Managing Director & Founder
Jan Brandes
Managing Director
Nikhil Parmar
Director
Olek Skwarczek
Analyst
Lukas Schlund
Analyst
Sale of 100% in
to
Sale of 100% in
for €135m to
10Bis