Presentation was made at the 4th Global Precision Medicine and Biomarkers Leaders Summit: Europe by Armin Furtwangler. For more information visit http://www.global-engage.com/wp-content/uploads/2017/04/Global-Precision-Medicine-Biomarkers-Europe-2017.pdf. Success through novel collaborations, valueadded services, and early patient involvement. Development of just new medications will no longer be a viable business model for the pharmaceutical industry in the short- to midterm. Therefore, we are working on innovative offerings for patients, doctors, and payers. These include, among many others, point-of care diagnostics, enabling quicker, diagnoses in a targeted manner. Other approaches include “smart devices”, applying modern sensor technologies, as well as “gamification” and other behavioural modification approaches to enhance patient compliance and adherence to their individual medications. The key to future success lies in collaborations with new partners, valueadded services, as well as application of innovative technologies, and most importantly – early involvement of patients at every step in the development process.

1. September 21st, 2017Dr. med. Armin Furtwaengler
Success through
novel collaborations,
value-added services,
and early patient involvement

2. 4th Global Precision Medicine
& Biomarkers Leaders Summit: Europe
Munich, September 21-22, 2017
Dr. med. Armin Furtwängler
Boehringer Ingelheim GmbH
The views expressed are those of the speaker, and do not necessarily represent an official Boehringer Ingelheim position!
Success through
novel collaborations,
value-added services,
and early patient involvement

3. PRESENTATION – OVERVIEW OF TOPICS
• Disruption in Healthcare
• Definition of Digital Health
• Collaborations with
 Academia
 Physicians & Hospitals
 Patients
 Technology Companies
 Consortia

4. Game-Changers

5. Disruption in Healthcare (by 2025)
• Existing healthcare institutions will be crushed as new business models with better
and more efficient care emerge.
• Thousands of startups, as well as today's data giants (Google, Apple, Microsoft,
SAP, IBM, etc.) will all enter this lucrative $3.8 trillion healthcare industry with new
business models that dematerialize, demonetize and democratize today's
bureaucratic and inefficient system.
• Biometric sensing (wearables) and AI will make each of us the CEOs of our own
health.
• Large-scale genomic sequencing and machine learning will allow us to understand
the root cause of cancer, heart disease and neurodegenerative disease and what
to do about it.
• Robotic surgeons can carry out an autonomous surgical procedure perfectly (every
time) for pennies on the dollar. Each of us will be able to regrow a heart, liver, lung
or kidney when we need it, instead of waiting for the donor to die.
PETER DIAMANDIS
Copyright 2017 by Dr. Armin Furtwaengler - Confidential!
5

6. Eric Topol
CELL,Volume 157, Issue 1
27 March 2014
Pages 241–253

7. Waves of „Digital Disruption“
1995+
Music
Photography
Video Rental
…
2005+
Print Media
TV
Travel
Real-Estate
HR
…
2015+
Finance
Healthcare
Automotive
Retail
Education
Telco
…
2020+
ALL Safe Havens
will be
subject to
digital disruption!!!
Copyright 2017 by Dr. Armin Furtwaengler - Confidential!
77

8. „Digital Health“ defined …
Wearables E-HealthBig Data
Health 2.0
Tele-Health
Personalized Medicine
Genomics
Sensing Technology
Tele-Medicine
Wireless
Insideables
Cloud Computing
m-Health
Integrated Circuits
Digital Health is the Convergence
of the Digital and Genomic Revolutions
with Health, Healthcare, Living, and Society
Internet of Things
Health-IT
Social Networking
Body Area Networks
8Copyright 2017 by Dr. Armin Furtwaengler - Confidential!

9. Burning Platform – Threats and Opportunities
Cost
Pressure
Entry of
other Industries
Data as
Insight Catalyst
New
Technological
Capabilities
Personalized Care
New Generation
Partnerships
New Engagement
Channels
Data Harvesting
/ Mining
Decentralized Care
Need to Reduce
Ecosystem Inefficiencies
Shift to Prevention
Value / Outcome
Based Care
9Copyright 2017 by Dr. Armin Furtwaengler - Confidential!

12. 12

13. “From Quantified Self to Quantified Health:
The healthcare industry is poised to start treating illnesses with help from big data.”
Daniel Kraft MD
13

14. New Technologies
WHAT DO THEY DO OR ENABLE?
DO THEY MAKE “THINGS” EASIER?
DO THEY MAKE “THINGS” LESS EXPENSIVE ?
WILL THEY ENABLE “THINGS” THAT WERE
NOT POSSIBLE, BEFORE?
WILL THEY ENABLE COMPLETELY NEW
INTERVENTIONS?
Copyright 2017 by Dr. Armin Furtwaengler - Confidential!
14

15. Disease
Progression
From „Sick Care“ to „Health Care“ and Well-being
Driving Medicine below the „Symptom Line“
• Predict Future
Risks
• Prevent Disease
• Promote Health
Pre-Disposition
Testing
Screening
Diagnosis - Prognosis
Drug / Device Intervention
Post-Treatment Testing
Health & Well-Being
Symptoms
Disease
Time
Copyright 2017 by Dr. Armin Furtwaengler - Confidential!
15

16. Challenges of a
highly volatile,
dynamic and
unpredictable
environment …
16

17. Moving from Healthcare to Health
17

18. New Ecosystem - Convergence of Health Providers -*
Pharma
Care
Wellness
Nutrition
Clothing
Converging Market
Health, Beauty,
Body & Soul
Sport / Fitness
Medicine
Body Care &
Cosmetics
Mobility
„Driverless Cars“
Patient
„Empowerment“
Housing
„Smart Home“
Medical
Engineering
Insurances
Mental Health
Copyright 2017 by Dr. Lutz Groh & Dr. Armin Furtwaengler - Confidential!
Labour
Customer Needs: PATIENT
+ Customer
+ Partner
18

19. Partnerships between
Pharmaceutical Companies, Academia
and Technology Companies

20. DIGITAL HEALTHCARE
Value-added Services
IBM Watson
23andMe
Galvani2/
Verily
Propeller
Health
Apple
McLaren
SAS
Qualcomm
Propeller
Health
PatientsLike
Me
Onduo3/Verily
Medtronic
PatientsLike
Me
Science 371
Voluntis
Voluntis
Senseonics
Qualcomm
23andMe
PatientsLike
Me
Qualcomm
Proteus
Microsoft
Rani
Therapeutics
Apple
Verily
(Google)
dRx Capital
Propeller
Health
1 A dRx Capital company (dRx Capital is a JV between Novartis and Qualcomm)
2 Galvani is a JV between GSK and Google’s Verily
3 Onduo is a JV between Sanofi and Google’s Verily
Key:
Cloud/Big Data/
Analytics
Patient Digital
Management Services
Connected Devices/
Drug Delivery
Monitoring/Adherence
Other
Patient
Access
Schemes
Nurse
Support
Patient
Support
Health
Management
Initiatives
OTHERS
Note: This is not an exhaustive list.
Recent partnerships in innovation in healthcare:
Are value-added services the next blockbuster?

21. The Digital Healthcare Universe 2017
Source: EY

22. Partnerships with
Physicians and Hospitals

23. https://angels-initiative.com/
https://eso-stroke.org/angels-initiative/

24. The
Internet
of
Medical
Things
Source of Clipart:
medicalfuturist.com
Copyright 2017 by Dr. Armin Furtwaengler - Confidential! 24

25. Partnerships with Patients …
Real-time Monitoring and Guidance
for Patients with Respiratory Diseases

26. 26

27. Copyright 2017 by Dr. Armin Furtwaengler - Confidential!
27

28. Partnership with Patients …
Social Media Platform
for Patients with „Rare (Orphan) Diseases“

29. 29

30. https://www.patientslikeme.com/conditions/1954 Copyright 2017 by Dr. Armin Furtwaengler - Confidential!
30

31. Partnerships
with Leading Technology Provider(s)

32. Copyright 2017 by Dr. Armin Furtwaengler - Confidential!
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33. 33 33

34. Summary
„Internet of (Medical) Things“ is here …
… and will change relationship with customers, i.e.
the patients, in a – truly revolutinary way
Patients will be empowered and the „decision
makers“ (CEOs) of their own health
Copyright 2017 by Dr. Armin Furtwaengler - Confidential!
34

36. End of Presentation
Back-up Slides

37. Copyright 2017 by Dr. Armin Furtwaengler - Confidential! 37

38. Data Privacy and Security Challenges
Copyright 2017 by Dr. Armin Furtwaengler - Confidential!
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40. We need leadership
that‘s playing to win …
… rather than
playing not to lose!
40