2. BIOREACTORS
• A bioreactor is a vessel in which a chemical process is
carried out which involves organisms or biochemically
active substances derived from such organisms.
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8. Disposable bioreactors
• Disposable bioreactors represent modern alternatives to such
traditional cultivation systems.These bioreactors consist of a
sterile plastic chamber that is partially filled with media(10% to
55%) , inoculated with cells and discarded after harvest.
• The single use chamber eliminating any need for cleaning or
sterilization is made of FDA-approval biocompatible plastic
such as polyethylene, polystyrene and polypropylene.
Usually, the disposable bioreactors are low cost, simple to
operate and guarantee high process security
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10. Non agitated bioreactors
• Various types of membrane reactor were configured
namely Hollow fiber reactor,Tubular membrane
reactor, Flat plate membrane reactor with one side or two
side flow, Multimembrane reactor
• Fluidized bed reactor
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11. Uses and advantages
• These bioreactors are mostly used in suspension culture
for large scale production of secondary metabolites.
• They are used in biotransformation of compounds
• Reduces labour
• More utilization in pharmaceutical industry
• More successful biomass production than the use of plant
as bio factories
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12. Disadvantage
• Instability of the productive cell lines,
• The slowness of the cell growth and production phase
• Limited knowledge about the secondary metabolite
pathways.
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