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PARASYMPATHETIC
NERVOUS SYSTEM
DEFINATION:
Parasympathetic nervous system
is a division of autonomic nervous system.
Parasympathetic nervous system is sometimes
referred to as the “rest and digest” system. In
general,the PNS (parasympathetic nervous
system) acts on the opposite way to
SNS(sympathetic nervous system),reversing the
effect of the fight or flight response. However it
may be more correct to say that the SNS and the
PNS have a complimentary relationship rather
than one of opposition.
Neurotransmitters:
Preganglionic neurotransmitter is Acetylcholine
(ach). And postganglionic neurotransmitter is
Noradrenaline.
The terminal nerve endings of parasympathetic
nervous system all or virtually all secrete
acetylcholine. Therefore, acetylcholine is called
parasympathetic transmiter.
The PNS uses acetylcholine as its primary
neurotransmitter, although peptides (such as
cholecystokinin) may acts on the PSNS as a
neurotransmitter.
When stimulated, the parasympathetic nerve
releases acetylcholine (ach) at the ganglion.
Acetylcholine in turn acts on nicotinic receptors
of post synaptic neurons.Post synaptic nerves
then releases acetylcholine to stimulate the
muscarinic receptors of the target organ.
Fibers:
The fibers that secrete acetylcholine are
said to be cholinergic. Those that secrete
norepinephrine are said to be adrenergic, a term
derived from adrenalin, which is an alternate
name for epinephrine. All preganglionic neurons
are cholinergic in both the sympathetic and
parasympathetic nervous systems.
Acetylcholine and acetylcholine like substances,
when applied to the ganglia, will excite both
sympathetic and parasympathetic postganglionic
neurons of parasympathetic system are also
cholinergic.
Conversely, most of the postganglionic sympathetic
neurons are adrenergic.
The parasympathetic system, like the
sympathetic system has both preganglionic and
postganglionic neurons. However, except in the
case of a few cranial parasympathetic nerves, the
preganglionic fibers pass uninterrupted all the
way to the organ that is to be controlled.
PREGANGLIONIC AND
POSTGANGLIONIC
PARASYMPATHETIC
NEURONS:
The postganglionic neurons are located in the wall of
the organ. The preganglionic fibers synapse with
these neurons, and extremely short postganglionic
fibers, a fraction of a millimeter to several
centimeters in length, leave the neurons to innervate
the tissue of the organ.
This location of parasympathetic postganglionic
neurons in the visceral orange is quite different from
the arrangement of the sympathetic ganglia because
the cell bodies of the sympathetic postganglionic
neurons are almost always located in the ganglia of
the sympathetic chain or in various other discrete
ganglia in the abdomen, rather in the excited organ.
EFFECTOR ORGANS
As the previous figure demonstrates that
parasympathetic fibers leave the central nervous system
through cranial nerves III,VII,and X; additional
parasympathetic fibers leave the lower most part of the
spinal cord through the second and third sacral spinal
nerves and occasionally the first and fourth sacral nerves.
About 75 percent of all parasympathetic nerve fibers are
in the vagus nerves ( cranial nerve X), passing to the entire
thoracic and abdominal regions of the body. Therefore a
physiologist speaking of the parasympathetic nervous
system often thinks mainly of two vague nerves.
The vague nerves supply parasympathetic nerves to
the hearts, lungs, esophagus, stomach, entire small
intestine, proximal half of the colon, liver, gallbladder,
pancreas, kidneys, and upper portions of uterers.
Parasympathetic fibers in third cranial nerve go to the
papillary sphincter and cillary muscle of the eye.
Fibers from the seventh cranial nerve pass to the
lacrimal, nasal and submandibular glands, and fibers
from the ninth cranial nerve go to the parotid gland.
The sacral parasympathetic fibers are in the pelvic
nerves which pass through the spinal nerve sacral
plexus on each side of the cord at the S2 and S3
levels.
These fibers then distribute to the descending
colon, rectum, urinary bladder, and lower portions
of ureters. Also, the sacral group of
parasympathetic supplies nerve signals to the
external genitalia to cause erection.
EFFECTS OF PARASYMPATHETIC
NERVES ON EFFECTORS
ORGANS EFFECTS
Eye
Iris
Cillary muscles
Contraction of circular Muscle
contraction
Blood vessels Usually nill
Skin
Sweat secretion
Erection of hairs
Generalized
Nill
Heart Inhibition
Salivary glands Free secretion and
vasodilation
Stomach
Contractions
Secretions
Sphincters
Augmentation
Increase
Relaxation(usually)
Intestine
Intestinal
Movements
Sphincters
Secretions
Augmentation
Relaxation(usually)
Increase
Gall bladder Contraction
Liver Nill
Spleen Nill
Pancreatic Secretions Increase
Bronchial muscles Contraction
Bronchial Secretions Increase
Kidneys Increase
Ureter Contraction
Bladder
fundus
Sphincter
Contraction
Relaxation
Sex organs (male) Erection
Uterus Variable

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PARASYMPATHETIC SYSTEM

  • 2. DEFINATION: Parasympathetic nervous system is a division of autonomic nervous system. Parasympathetic nervous system is sometimes referred to as the “rest and digest” system. In general,the PNS (parasympathetic nervous system) acts on the opposite way to SNS(sympathetic nervous system),reversing the effect of the fight or flight response. However it may be more correct to say that the SNS and the PNS have a complimentary relationship rather than one of opposition.
  • 3. Neurotransmitters: Preganglionic neurotransmitter is Acetylcholine (ach). And postganglionic neurotransmitter is Noradrenaline. The terminal nerve endings of parasympathetic nervous system all or virtually all secrete acetylcholine. Therefore, acetylcholine is called parasympathetic transmiter. The PNS uses acetylcholine as its primary neurotransmitter, although peptides (such as cholecystokinin) may acts on the PSNS as a neurotransmitter. When stimulated, the parasympathetic nerve releases acetylcholine (ach) at the ganglion.
  • 4. Acetylcholine in turn acts on nicotinic receptors of post synaptic neurons.Post synaptic nerves then releases acetylcholine to stimulate the muscarinic receptors of the target organ.
  • 5. Fibers: The fibers that secrete acetylcholine are said to be cholinergic. Those that secrete norepinephrine are said to be adrenergic, a term derived from adrenalin, which is an alternate name for epinephrine. All preganglionic neurons are cholinergic in both the sympathetic and parasympathetic nervous systems. Acetylcholine and acetylcholine like substances, when applied to the ganglia, will excite both sympathetic and parasympathetic postganglionic neurons of parasympathetic system are also cholinergic.
  • 6. Conversely, most of the postganglionic sympathetic neurons are adrenergic.
  • 7. The parasympathetic system, like the sympathetic system has both preganglionic and postganglionic neurons. However, except in the case of a few cranial parasympathetic nerves, the preganglionic fibers pass uninterrupted all the way to the organ that is to be controlled. PREGANGLIONIC AND POSTGANGLIONIC PARASYMPATHETIC NEURONS:
  • 8. The postganglionic neurons are located in the wall of the organ. The preganglionic fibers synapse with these neurons, and extremely short postganglionic fibers, a fraction of a millimeter to several centimeters in length, leave the neurons to innervate the tissue of the organ. This location of parasympathetic postganglionic neurons in the visceral orange is quite different from the arrangement of the sympathetic ganglia because the cell bodies of the sympathetic postganglionic neurons are almost always located in the ganglia of the sympathetic chain or in various other discrete ganglia in the abdomen, rather in the excited organ.
  • 9.
  • 10. EFFECTOR ORGANS As the previous figure demonstrates that parasympathetic fibers leave the central nervous system through cranial nerves III,VII,and X; additional parasympathetic fibers leave the lower most part of the spinal cord through the second and third sacral spinal nerves and occasionally the first and fourth sacral nerves. About 75 percent of all parasympathetic nerve fibers are in the vagus nerves ( cranial nerve X), passing to the entire thoracic and abdominal regions of the body. Therefore a physiologist speaking of the parasympathetic nervous system often thinks mainly of two vague nerves.
  • 11. The vague nerves supply parasympathetic nerves to the hearts, lungs, esophagus, stomach, entire small intestine, proximal half of the colon, liver, gallbladder, pancreas, kidneys, and upper portions of uterers. Parasympathetic fibers in third cranial nerve go to the papillary sphincter and cillary muscle of the eye. Fibers from the seventh cranial nerve pass to the lacrimal, nasal and submandibular glands, and fibers from the ninth cranial nerve go to the parotid gland. The sacral parasympathetic fibers are in the pelvic nerves which pass through the spinal nerve sacral plexus on each side of the cord at the S2 and S3 levels.
  • 12. These fibers then distribute to the descending colon, rectum, urinary bladder, and lower portions of ureters. Also, the sacral group of parasympathetic supplies nerve signals to the external genitalia to cause erection.
  • 13. EFFECTS OF PARASYMPATHETIC NERVES ON EFFECTORS ORGANS EFFECTS Eye Iris Cillary muscles Contraction of circular Muscle contraction Blood vessels Usually nill Skin Sweat secretion Erection of hairs Generalized Nill
  • 14. Heart Inhibition Salivary glands Free secretion and vasodilation Stomach Contractions Secretions Sphincters Augmentation Increase Relaxation(usually) Intestine Intestinal Movements Sphincters Secretions Augmentation Relaxation(usually) Increase
  • 15. Gall bladder Contraction Liver Nill Spleen Nill Pancreatic Secretions Increase Bronchial muscles Contraction Bronchial Secretions Increase Kidneys Increase Ureter Contraction