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1. BIOCHEMISTRY
[B. Pharm – I Yr.]
Topic: Proteins
Umesh Kumar
Assistant Professor
Dept. of Pharm. Chemistry
Hygia Institute of Pharmaceutical Education and Research

2. Contents
• Proteins
• Introduction
• Classification

3. Proteins
• Proteins are the most abundant biomolecules of
the living system.
• They occur in every part of the body and form
the fundamental basis of structure and functions
of life.
• They are also required for growth and
maintenance of body.
• The word protein is derived from Greek word,
“proteios” which means primary or of prime
importance.
• All proteins are polymers of α-amino acids.

4. • Proteins are known as building blocks of life.
• Proteins are organic substances; they are made up of nitrogen, oxygen,
carbon and hydrogen.
• Proteins are the structural elements of body tissues.
• Proteins are considered as the bricks, they make up bones, muscles, hair
and other parts of the body.
Conti……..

5. 1. Simple Proteins or Holoproteins
• These proteins are made of only one type of amino acid, as structural
component, on decomposition with acids, they liberate constituent amino
acids.
• They are mostly globular type of proteins except for scleroproteins, which are
fibrous in nature.
• Simple proteins are further classified based on their solubility:
I. Protamines and histones
II. Albumins
III. Globulins
IV. Scleroproteins or Albuminoids
Classification of Proteins

6. 2. Conjugated or Complex Proteins or Hetero-proteins:
• These are proteins that are made of amino acids and other organic compounds.
• The non-amino acid group is termed as prosthetic group.
• Complex proteins are further classified based on the type of prosthetic group
present-
a) Metalloproteins
b) Chromoproteins
c) Glycoproteins and Mucoproteins
d) Phosphoproteins
e) Lipoproteins
f) Nucleoproteins
Classification of Proteins

7. 3. Derived Proteins
• These are proteins that are derived from the action of heat, enzyme or
chemical reagents.
• Derived proteins are of two types,
A. Primary derived proteins
i. Derivatives of proteins, in which the size of the protein molecule is not
altered materially.
ii.Example: edestan, coagulated egg-white.
B. Secondary derived proteins.
i. While in secondary derived proteins, hydrolysis occurs, as a result the
molecules are smaller than the original proteins.
ii.They are further classified into 3 types - Proteoses, Peptones and
Polypeptides
Classification of Proteins

8. THANK YOU
HYGIA GROUP OF INSTITUTIONS
GHAILA ROAD, GAAZIPUR BALRAM,
FAIZULLAHGANJ, LUCKNOW