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Genetics 1.1: Introduction
Presented by Dr. Roman Saini
About me
• Trying to impart high quality accessible education
• If you want to know more, you can read online
• Spread the word of this education revolution
• Any query or doubt, please comment below the video on youtube or
on Facebook page: www.facebook.com/UnacademyMedical
Introduction to Genetics
• "Genetics" term by Bateson. Father - "Gregor John Mendel".
• Genetics: Branch of biology dealing with the inheritance as well as the
variation of characters from parents to offspring.
• Inheritance:
• Process by which characters are passed on from parents to progeny.
• Basis of heredity.
• Variation: Degree by which progeny differ from their parents.
Variations
1. Somatic Variations:
• Non-inheritable variation.
• Occurs in somatic cell.
• E.g. Hair length of human being.
2. Blastogenic or Germinal Variations:
• Inheritable variation.
• Occurs at germplasm level or in reproductive body part.
2 types of Blastogenic variations
1. Continuous Variations: Occurs due to crossing over or genetic
recombinations.
2. Discontinuous Variations: Sudden genetic changes in reproductive
cells due to environmental fluctuations. Known as Mutations or
Saltations. Two types-
• Meristic Variations: Change in quantity.
• Substantive Variations: Change in quality, e.g. polydactyl.
Types of Genetics
• Classical or Transmission Genetics: Fundamental study of genetics.
Involves study of transfer of characters.
• Forward Genetics: Phenotype Protein RNA DNA.
Types of Genetics
• Reverse Genetics: DNA RNA Protein Phenotype.
• Population Genetics: Study of distribution of a particular gene in
population with respect to its dominant and recessive traits.
• Molecular Genetics: Study of genetics at molecular level. Three
aspects- Structural Genetics, Functional Genetics and Applied
Genetics.
Blending Inheritance
Pre-Mendelian Ideas. Includes-
• Moist Vapor Theory by Pythagoras.
• Reproductive Blood Theory by Aristotle.
• Homunculus or Pre-formation Theory by Swammerdam.
• Theory of Pan-genesis by Darwin.
• Weismann's Theory.
Exception of Blending Inheritance:
• Atavistic Characteristic: Characters which are observed in some
offspring but they are not present in their parents. Ancestral
characteristic.
Evidences in favor of Blending Inheritance:
• Incomplete dominance of Mirabilis Jalapa for flower color.
• Polygenic inheritance of skin color, human intelligence, human
height, they sometime exhibit blending.
Terminology
• Character: Expressible form of any phenotype.
• Contrasting character: Character having more than one variant. All
characters are not contrasting characters.
• Trait: Detectable variant of a character.
• Gene or Factor: Unit of inheritance. Contain information that is
required to express a particular trait in an organism.
• Allele: Different forms of the same gene coding for a pair of
contrasting traits.
• Homozygous: Having two identical alleles of a gene e.g. TT or tt.
• Heterozygous: Having two different alleles of a gene e.g. Tt.
• Monohybrid Cross: Cross applied for one character only.
• Dihybrid Cross: Cross applied for two characters.
• Dominant: Phenotypic expression which can express itself in
homozygous as well as heterozygous combination by suppressing
expression of another trait.
• It is designated by capital letter.
• Recessive: Phenotypic expression which can express itself only in
homozygous combination.
• It is designated by small letter.
Spread the word and be a part of this education revolution
www.facebook.com/romansaini.official
Spread the education-for-all revolution
@theUnacademy
@RomanSaini
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Genetics 1.1 introduction

  • 2. About me • Trying to impart high quality accessible education • If you want to know more, you can read online • Spread the word of this education revolution • Any query or doubt, please comment below the video on youtube or on Facebook page: www.facebook.com/UnacademyMedical
  • 3. Introduction to Genetics • "Genetics" term by Bateson. Father - "Gregor John Mendel". • Genetics: Branch of biology dealing with the inheritance as well as the variation of characters from parents to offspring. • Inheritance: • Process by which characters are passed on from parents to progeny. • Basis of heredity. • Variation: Degree by which progeny differ from their parents.
  • 4. Variations 1. Somatic Variations: • Non-inheritable variation. • Occurs in somatic cell. • E.g. Hair length of human being. 2. Blastogenic or Germinal Variations: • Inheritable variation. • Occurs at germplasm level or in reproductive body part.
  • 5. 2 types of Blastogenic variations 1. Continuous Variations: Occurs due to crossing over or genetic recombinations. 2. Discontinuous Variations: Sudden genetic changes in reproductive cells due to environmental fluctuations. Known as Mutations or Saltations. Two types- • Meristic Variations: Change in quantity. • Substantive Variations: Change in quality, e.g. polydactyl.
  • 6. Types of Genetics • Classical or Transmission Genetics: Fundamental study of genetics. Involves study of transfer of characters. • Forward Genetics: Phenotype Protein RNA DNA.
  • 7. Types of Genetics • Reverse Genetics: DNA RNA Protein Phenotype. • Population Genetics: Study of distribution of a particular gene in population with respect to its dominant and recessive traits. • Molecular Genetics: Study of genetics at molecular level. Three aspects- Structural Genetics, Functional Genetics and Applied Genetics.
  • 8. Blending Inheritance Pre-Mendelian Ideas. Includes- • Moist Vapor Theory by Pythagoras. • Reproductive Blood Theory by Aristotle. • Homunculus or Pre-formation Theory by Swammerdam. • Theory of Pan-genesis by Darwin. • Weismann's Theory.
  • 9. Exception of Blending Inheritance: • Atavistic Characteristic: Characters which are observed in some offspring but they are not present in their parents. Ancestral characteristic.
  • 10. Evidences in favor of Blending Inheritance: • Incomplete dominance of Mirabilis Jalapa for flower color. • Polygenic inheritance of skin color, human intelligence, human height, they sometime exhibit blending.
  • 11. Terminology • Character: Expressible form of any phenotype. • Contrasting character: Character having more than one variant. All characters are not contrasting characters. • Trait: Detectable variant of a character. • Gene or Factor: Unit of inheritance. Contain information that is required to express a particular trait in an organism.
  • 12. • Allele: Different forms of the same gene coding for a pair of contrasting traits. • Homozygous: Having two identical alleles of a gene e.g. TT or tt. • Heterozygous: Having two different alleles of a gene e.g. Tt. • Monohybrid Cross: Cross applied for one character only. • Dihybrid Cross: Cross applied for two characters.
  • 13. • Dominant: Phenotypic expression which can express itself in homozygous as well as heterozygous combination by suppressing expression of another trait. • It is designated by capital letter. • Recessive: Phenotypic expression which can express itself only in homozygous combination. • It is designated by small letter.
  • 14. Spread the word and be a part of this education revolution
  • 15. www.facebook.com/romansaini.official Spread the education-for-all revolution @theUnacademy @RomanSaini Hit thumbs up Thank you for watching the tutorial www.facebook.com/unacademy