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How does the cell control the level of HIF1 alpha activation The pho.pdf

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How does the cell control the level of HIF1 alpha activation? The phosphorylation status of HIF1 alpha is the main mechanism to regulate HIF1 alpha activity. A ligand binds to HIF1 alpha inducing its translocation into the nucleus. The cell controls the level of ARNT A prolyl hydroxylase controls the level of HIF1 alpha proline hydroxylation that can in turn regulate HIF1 alpha proteolysis..

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How does the cell control the level of HIF1 alpha activation? The phosphorylation status of HIF1 alpha is the main mechanism to regulate HIF1 alpha activity. A ligand binds to HIF1 alpha inducing its translocation into the nucleus. The cell controls the level of ARNT A prolyl hydroxylase controls the level of HIF1 alpha proline hydroxylation that can in turn regulate HIF1 alpha proteolysis.

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