Vagal Nerve Stimulation for epilepsy

INTRODUCTION ,[object Object],[object Object]

Schematic drawing of the general placement of the vagus nerve stimulation system and bipolar stimulating lead

VNS Therapy: components ,[object Object],[object Object],[object Object],[object Object],[object Object]

PULSE GENERATOR & BIPOLAR LEAD

The Model 400 NCP Tunneling Tool is used during implantation to create a subcutaneous path between the device in the chest and the vagus nerve in the neck

procedure ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Use of programming wand to adjust generator stimulator parameters

stimulation parameter settings

Vagus nerve anatomy and mechanism of action of VNS

Mechanism of action ,[object Object],[object Object],[object Object]

Indication ,[object Object],[object Object]

indications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Efficacy, LABAR etal ,[object Object],[object Object],[object Object],[object Object]

Hosain etal in LGS ,[object Object],[object Object],[object Object],[object Object],[object Object]

MURPHY etal, ,[object Object],[object Object],[object Object],[object Object]

PARKER etal, ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

PATWARDAN etal, ,[object Object],[object Object],[object Object]

Sirven etal, ,[object Object],[object Object],[object Object],[object Object]

RESPONDER RATES.E03,E05 STUDIES

responder rates for several of the newer AEDs with VNS ,[object Object]

Non epileptic indications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Safety&tolerability ,[object Object],[object Object],[object Object],[object Object],[object Object]

Clinical use of VNS for epilepsy

Clinical usage,programming ,[object Object],[object Object],[object Object],[object Object]

Efficacy of rapid cycling vagus nerve stimulation in pharmaco-resistant epilepsy ,[object Object],[object Object]

To conclude ,[object Object],[object Object],[object Object],[object Object],[object Object]

Vagal Nerve Stimulation for epilepsy

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Vagal Nerve Stimulation for epilepsy