7. Pop are ideal for conditions
were estrogen is
contraindicated
…… irregular bleeding
8.
9. Estrogen- ethyl estradiol 50μg(20-
35)
Progesterone-generation progestogen
first Norethynodrel, norethisterone
acetate and lynestrenol
second Norgestrel, levonorgestrel
third Desogestrel, gestodene,
norgestimate
newer drospirenone
10. First generation;-50 μg ethinyl estradiol or
more
moderate antrogenic activity
:ovral
Second generation: 20-30μ ethinyl estradiol
:ovral –L, malaN , malaD
11. Third generation:
• less antrogenic
• Increase sexhormone binding globulins
and decrease free testosterone
• Less effect on lipid profile-stroke and mi
• Less effect on body weight
• Beneficial in acne , hirsuitism
Venous thromboembolism
:novelon , femilon
12. Newer progestogens:
• Like natural progestrone
antimineralocorticoid
activity
no androgenic action
-hisuitism, acne
-fluid retention on coc
: yasmin, crisanta, tarana
19. Contraindications- absolute
• Ischemic heart disease
• Valvular heart disease
• Porphyria
• Epilepsy or migraine with
aura
• Active liver disease
• Hypercholestrolemia
• Arterial and venous
thrombosis
• Women above 35 and obese
or smoke
Relative
• Obesity , HTN , obesity, family
history
• Patients on anti tuberculosis
20. • Venous thromboembolism
• Arterial thrombosis
• HTN
• Glucose metabolism
• Lipid metabolism
• Breast and cervical cancer
• Liver- adenoma, gallstone
,cholestatic jauntice
• Break through bleeding