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[object Object],[object Object],Slide show modified from Kim Foglia @  http://www.explorebiology.com
4  MAJOR  MACROMOLECULES ,[object Object],[object Object],[object Object],[object Object]
POLYMERS ,[object Object],[object Object],[object Object],Image by Riedell
SEE ANANIMATION
SEE ANANIMATION
CARBOHYDRATES http://www.graphic-design.com/Type/sugar/index.html http://www.ifr.ac.uk/SPM/images/Starch%20products.jpg
MONOSACCHARIDES Simple sugar molecules C 6 H 12 O 6 http://www.cybercolloids.net/library/sugars/glyceraldehyde.gif http://www.estrellamountain.edu/faculty/farabee/biobk/BioBookCHEM2.html http://217.60.75.10/llt/biokemi/images/galactose.jpg http://217.60.75.10/llt/biokemi/images/galactose.jpg http://www.estrellamountain.edu/faculty/farabee/biobk/BioBookCHEM2.html C 5 H 10 O 5 D-glyceraldehyde C 3 H 6 O 3 Composed of C,H,O  (CH 2 O)n  3-7 carbons Name often ends in –ose
NUMBERING ,[object Object],[object Object]
Is it D or L ? ,[object Object],[object Object],[object Object]
Pentoses and  hexoses can  cyclize in water See animation ,[object Object],[object Object]
CARBOHYDRATES SUPPLY ENERGY Images  from:  http://www.miranda.com/library.en/Images/Pictures/girls-runners.jpg http://www.estrellamountain.edu/faculty/farabee/biobk/BioBookCHEM2.html Cells burn glucose and store the  energy released as ATP
[object Object],[object Object],[object Object],[object Object],[object Object],http://faculty.clintoncc.suny.edu/faculty/michael.gregory/files/Bio%20101/Bio%20101%20Lectures/Biochemistry/bioche1.gif http://www.biotech.iastate.edu/lab_protocols/HSSB-TLC_images/sucrose.gif
DISACCHARIDES ,[object Object],[object Object],[object Object]
POLYSACCHARIDES~ “many sugars”  ,[object Object],[object Object],[object Object],[object Object],http://www.langara.bc.ca/biology/mario/Assets/Amylopectin.jpg http://www.district87.org/biology87/apbio/biochem/Activity6_notes.pdf
POLYSACCHARIDES~ “many sugars”  TWO KINDS OF STARCH:   amylose = unbranched starch amylopectin = branched starch http://www.langara.bc.ca/biology/mario/Assets/Amylopectin.jpg
POLYSACCHARIDES~ “many sugars”  EX: GLYCOGEN alpha 1-4 glycosidic bonds like starch More branched than amylopectin FUNCTION:  Energy storage in ANIMALS Stored in liver and  muscle tissue http://www.abcbodybuilding.com/magazine04/scientific.htm
POLYSACCHARIDES~ “many sugars”  FUNCTION: Structural PLANTS ~ CELLULOSE Major component in cell walls Most abundant organic compound on Earth beta (ß) 1-4 glycosidic linkages
[object Object],[object Object],[object Object],[object Object]
POLYSACCHARIDES FUNCTION: Structural EX: CHITIN Structural polysaccharide made from ß glucose with a NITROGEN containing group attached
[object Object],[object Object]
 
 
 
 
FATTY ACIDS USED CAN : ,[object Object],[object Object],[object Object],[object Object],[object Object],Kink in chain wherever  a  cis double  bond occurs
FATS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Lipids, II
Phospholipids ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
!
 
 
 
 
 
PROTEINS http://images.foodnetwork.com/webfood/images/gethealthy/nutritionalallstars/LeanProteins_header.jpg
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Each kind of amino acid has a different R group 20 different amino acids are used by cells to make proteins  (There are a few other aa’s, but rare) R GROUPS
See ananimation
POLYPEPTIDES http://www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBookCHEM2.html http://www.cherishedtimedesigns.com/images/BaliCharmBraceletGraduation500.jpg ,[object Object],[object Object]
Image from:    http://www.tvdsb.on.ca/saunders/courses/online/SBI3C/Cells/Protein-Structure03.jpg A functional PROTEIN is not just the polypeptide chain. A PROTEIN consists  of one or more  polypeptide chains  twisted, folded,  and coiled into a unique molecular shape What determines the shape? SEE AN ANIMATION
 
 
 
 
 
PROTEIN STRUCTURE & FUNCTION ,[object Object],[object Object],[object Object]
 
Primary Structure ,[object Object],A T
Secondary Structure folding along short sections   ,[object Object],[object Object],[object Object],[object Object],[object Object]
Tertiary Structure interactions between side chains ,[object Object],[object Object],[object Object],[object Object]
Functional Groups ,[object Object],[object Object],http://www.mun.ca/biology/scarr/Disulfide_bridge.htm
DISULFIDE BRIDGES ,[object Object],http://sandwalk.blogspot.com/2007/02/disulfide-bridges-stabilize-folded.html BETWEEN nearby CYSTEINE amino acids (Notice name change    when bonded)
Quaternary Structure ,[object Object],[object Object],[object Object]
See ananimation
WHAT DO PROTEINS DO? * See page 78 in Campbell for other examples
ENZYMES http://www.biologie.uni-hamburg.de/b-online/library/cat-removed/enzyme_.gif Enzymes are protein catalysts  that accelerate chemical reactions  in living things Enzymes reduce activation energy  required for reaction Enzymes are specific and fit  substrate like a lock and key. Enzymes are not changed  by reaction and are reusable. http://www.grand-illusions.com/images/articles/toyshop/trick_lock/mainimage.jpg
[object Object],[object Object],[object Object],[object Object],http://www.desktopfotos.de/Downloads/melt_cd.jpg http://www.nealbrownstudio.com/adm/photo/163_nb_fried_egg.jpg See a movie Choose narrated
[object Object],[object Object],Facilitation of folding
 
NUCLEIC ACIDS
Nucleic Acids ,[object Object]
Nucleic Acids ,[object Object],[object Object]
Nucleic Acids ,[object Object],[object Object],[object Object]
Nucleic Acids ,[object Object],ribose deoxyribose OR
Nucleic Acids ,[object Object],[object Object],[object Object],[object Object]
Deoxyribonucleic acid (DNA) ,[object Object],[object Object],[object Object],[object Object],http://staff.um.edu.mt/acus1/3Molgen.htm
 
DNA ,[object Object],Image from:  http://sbchem.sunysb.edu/msl/dna.gif
Deoxyribonucleic acid (DNA) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Deoxyribonucleic acid (DNA) ,[object Object],http://www.biology.arizona.edu/biochemistry/problem_sets/large_molecules/06t.html
Deoxyribonucleic acid (DNA) ,[object Object],[object Object],[object Object],http://staff.um.edu.mt/acus1/3Molgen.htm
Nucleic Acids ,[object Object],[object Object],[object Object],[object Object]
Ribonucleic acid (RNA) Ribose sugar Nitrogeneous bases: A, C, G, and U SINGLE STRANDED http://www.biology.arizona.edu/biochemistry/problem_sets/large_molecules/06t.html
RNA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Deoxyribonucleic acid (DNA) Ribonucleic acid (RNA) DNA -> RNA -> protein
NUCLEOTIDES can transfer and store energy Adenosine triphosphate (ATP)
NUCLEOTIDES can transfer and store energy NAD + NADP + FAD Coenzyme A Energy and electron carriers used in photosynthesis and respiration More on this next unit!

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