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Stanford-India Biodesign


Rajiv Doshi, MD
Executive Director (US), Stanford-India Biodesign
Consulting Assistant Professor of Medicine
Lecturer in Mechanical Engineering
Stanford University
rdoshi@stanford.edu




                                                    1
Stanford-India Biodesign: Mission


 To develop leaders in medical technology innovation in India

 To create medical technologies for India

 To fuel growth of the Indian medical technology industry




        Educate. Collaborate. Innovate.



                                                                 2
Stanford-India Biodesign Institutions

 All India Institute of Medical Sciences (AIIMS)
 Indian Institute of Technology (IIT) Delhi
 Stanford University




                                                    3
Stanford-India Biodesign Sponsors

 Department of Biotechnology, Government of India
 Indo-US Science & Technology Forum
 Lemelson Foundation
 Stryker Corporation
 Orbees Medical
 Artiman Ventures




                                                     4
Key Objectives

 Ecosystem development
 Human resources development
     “Training the trainers”
     Training large numbers of engineers and physicians at India’s top
      institutions

 Building sites of medical technology excellence
     Bridging academia and industry




                                                                          5
Team (Stanford)

 Rajiv Doshi, MD
    –   Executive Director, Stanford-India Biodesign (US)
    –   Consulting Assistant Professor of Medicine, Stanford University
 Anurag Mairal, PhD
    –   Associate Director, Program Development, Stanford-India
        Biodesign
 Uday Kumar, MD
    –   Associate Director, Curriculum, Stanford-India Biodesign
 Christine Kurihara
    –   Associate Director, Operations, Stanford-India Biodesign
 Saloni Doshi
    –   Strategic Advisor, Stanford-India Biodesign
 Paul Yock, MD
    –   Director of Stanford Biodesign
    –   Professor of Cardiology, Stanford University


                                                                          6
Team (India)

       Balram Bhargava, MD
    –    Executive Director, Stanford-India Biodesign (India)
    –    Professor of Cardiology, AIIMS
       Alok Ray, PhD
    –    Director, Stanford-India Biodesign (India)
    –    Professor of Biomedical Engineering, IIT Delhi
       Sakti Srivastava, MD
    –    Associate Director, Academic Outreach (US), Stanford-India
         Biodesign
    –    Consulting Associate Professor of Surgery, Stanford University
       Sandeep Singh, MD
    –    Associate Professor of Cardiology, AIIMS




                                                                          7
About Stanford Biodesign

 Created in 2000 by cardiologist Paul Yock, MD to train leaders in
  medical technology innovation
 Series of initiatives to promote medical technology innovation and
  entrepreneurship
    – A fellowship program leading to VC backed companies

    – Direct and indirect affiliation with numerous courses
         • Engineering (Mechanical, chemical, electrical, industrial)

         • Business

         • Medicine

         • Law

    – National conferences to promote best practices in medical technology
      innovation

 Strong ties to industry, venture capital

                                                                             8
Stanford Biodesign:
        One Course Leads to Many Others

   ME 394        Medical Device Design
   BIOE 70Q      Medical-Device Innovation
   BIOE 374      Biodesign Innovation
   EE 202        Medical Electronics
   IMMUNOL 230   Introduction to Medicine
   ME 208        Patent Law and Strategy for Innovators and Entrepreneurs
   ME 382        Biomedical Device Design & Evaluation
   MED 217       Medico-Technological Frontiers of Digestive Diseases
   MED 276       Introduction to the Medical Technology Industry and Its Career
   MS&E 256      Technology Assessment and Regulation of Medical Devices
   NSUR 278      From Science to Business: Innovation in Neurological Disease
   NSUR 279      Concepts in Drug Device Combination Products




                                                                                   9
Biodesign Companies to Date




                              10
Initial Planning Meetings in Delhi:
January 2007




                                      11
Stanford-India Biodesign Offerings

 Stanford-India Biodesign Fellowships (Begun)
 India Biodesign Internships at AIIMS/IIT Delhi (Begun)
 Medical Device Innovation courses to be offered across India (2010)
 Core Stanford Biodesign innovation lectures to be offered online (Begun)
 Global student/faculty exchanges (Begun)
 National Indian Med Tech summit (Begun)
 Support of nationwide innovation contests (Begun)
 Creation of SIB Centers
    – 2008: First SIB Center in New Delhi (Begun)
 www.indiabiodesign.org networking community (Begun)



                                                                             12
Stanford-India Biodesign Fellowships

 1-2 year fellowships housed at Stanford and New Delhi
 Interdisciplinary, team-based learning combining engineering, clinical and
  business trainees
 Intensive exposure to medical needs-finding within the Indian setting
 Teams invent, develop, patent and commercialize technologies
 Mentoring by world class faculty at Stanford, IIT Delhi and AIIMS
 Mentoring by “real world” industry experts and advisors in the US and
  India
    – Technology innovators, legal, venture capital




                                                                               13
Fellowship Selection Process

 300 worldwide applicants (Indian citizens)

 17 Semi-finalists interviewed in New Delhi

 8 Finalists interviewed at Stanford

 5 Fellows selected




                                               14
2008 Fellows

 Nishith Chasmawala
    –   Johnson & Johnson, Medtronic
 Srinivas Jaggu
    –   Kirloskar, General Electric
 Jayant Karve
    –   General Electric
 Amit Sharma
    –   IIT Delhi
 Sandeep Singh, MD
    –   Associate Professor of Cardiology, AIIMS




 New Fellows arrived January 2009
    –   Includes 2 Professors from IIT Madras, IIT Delhi


                                                           15
Fellowship Timeline




                      16
Post-Fellowship Activities

      Track 1
          – Start med tech company in India

      Track 2
          – Join multinational or other established med tech company
          – Pursue “intrapreneurial” activities

      Track 3
          – Return to academia
          – Teach Biodesign fundamentals in India



All fellows are expected to remain in India and maintain a mentoring relationship with SIB



                                                                                             17
Indian Biodesign Internships at AIIMS/IIT Delhi

  3-6 month concentrated exposure at AIIMS/IIT Delhi
  Goal is to get (less complicated) products to market quickly
  Teaching staff to include Fellows, Professors at AIIMS, IIT
  Interns to include engineering students and engineers/business people
   from industry
  Began October 2008




                                                                           18
Medical Device Innovation Course at Multiple
            Indian Universities

 To be broadly deployed at top engineering institutions in India
 Based on similar Medical Device Design course at Stanford
 Customized for India
 Can accommodate ~30 undergraduate and graduate students
 Part didactic, part project (prototyping)
 Core lectures designed by Stanford-India Biodesign
 Projects led by practicing physicians
    – 3-4 students per team




                                                                    19
First Annual Indian Med Tech Summit




                                      20
First Stanford-India Biodesign Centre
         (AIIMS—New Delhi)




                                        21
Support of National Med Tech Innovation Contest
             Through IIT Bombay




                                                  22
www.indiabiodesign.org




                         23
Potential Benefit for India

 Greatly increased exposure to medical technology innovation at
  university level to significantly increase graduates with interests
  in medical technology careers
 Development of academic faculty capable of training dozens of
  future med tech leaders per year
 Development of industry leaders capable of leading
  entrepreneurial or “intrapreneurial” initiatives
 Development of New Delhi (and second location TBD) to serve
  as hubs of medical technology innovation
 Development of an ecosystem that is sorely lacking
 Matching of job applicants with employers
 Devices made expressly for the needs of Indians and others in
  developing countries




                                                                        24
Getting Involved

 Advisors and mentors still needed
 Funding needed to scale program
    – Corporates
    – VCs
    – Foundations
    – Individuals
 If interested, please email me at rdoshi@stanford.edu



   We need the community’s help to achieve the greatest impact




                                                                 25

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Stanford-India Biodesign: Fueling Medical Innovation in India

  • 1. Stanford-India Biodesign Rajiv Doshi, MD Executive Director (US), Stanford-India Biodesign Consulting Assistant Professor of Medicine Lecturer in Mechanical Engineering Stanford University rdoshi@stanford.edu 1
  • 2. Stanford-India Biodesign: Mission  To develop leaders in medical technology innovation in India  To create medical technologies for India  To fuel growth of the Indian medical technology industry Educate. Collaborate. Innovate. 2
  • 3. Stanford-India Biodesign Institutions  All India Institute of Medical Sciences (AIIMS)  Indian Institute of Technology (IIT) Delhi  Stanford University 3
  • 4. Stanford-India Biodesign Sponsors  Department of Biotechnology, Government of India  Indo-US Science & Technology Forum  Lemelson Foundation  Stryker Corporation  Orbees Medical  Artiman Ventures 4
  • 5. Key Objectives  Ecosystem development  Human resources development  “Training the trainers”  Training large numbers of engineers and physicians at India’s top institutions  Building sites of medical technology excellence  Bridging academia and industry 5
  • 6. Team (Stanford)  Rajiv Doshi, MD – Executive Director, Stanford-India Biodesign (US) – Consulting Assistant Professor of Medicine, Stanford University  Anurag Mairal, PhD – Associate Director, Program Development, Stanford-India Biodesign  Uday Kumar, MD – Associate Director, Curriculum, Stanford-India Biodesign  Christine Kurihara – Associate Director, Operations, Stanford-India Biodesign  Saloni Doshi – Strategic Advisor, Stanford-India Biodesign  Paul Yock, MD – Director of Stanford Biodesign – Professor of Cardiology, Stanford University 6
  • 7. Team (India)  Balram Bhargava, MD – Executive Director, Stanford-India Biodesign (India) – Professor of Cardiology, AIIMS  Alok Ray, PhD – Director, Stanford-India Biodesign (India) – Professor of Biomedical Engineering, IIT Delhi  Sakti Srivastava, MD – Associate Director, Academic Outreach (US), Stanford-India Biodesign – Consulting Associate Professor of Surgery, Stanford University  Sandeep Singh, MD – Associate Professor of Cardiology, AIIMS 7
  • 8. About Stanford Biodesign  Created in 2000 by cardiologist Paul Yock, MD to train leaders in medical technology innovation  Series of initiatives to promote medical technology innovation and entrepreneurship – A fellowship program leading to VC backed companies – Direct and indirect affiliation with numerous courses • Engineering (Mechanical, chemical, electrical, industrial) • Business • Medicine • Law – National conferences to promote best practices in medical technology innovation  Strong ties to industry, venture capital 8
  • 9. Stanford Biodesign: One Course Leads to Many Others  ME 394 Medical Device Design  BIOE 70Q Medical-Device Innovation  BIOE 374 Biodesign Innovation  EE 202 Medical Electronics  IMMUNOL 230 Introduction to Medicine  ME 208 Patent Law and Strategy for Innovators and Entrepreneurs  ME 382 Biomedical Device Design & Evaluation  MED 217 Medico-Technological Frontiers of Digestive Diseases  MED 276 Introduction to the Medical Technology Industry and Its Career  MS&E 256 Technology Assessment and Regulation of Medical Devices  NSUR 278 From Science to Business: Innovation in Neurological Disease  NSUR 279 Concepts in Drug Device Combination Products 9
  • 11. Initial Planning Meetings in Delhi: January 2007 11
  • 12. Stanford-India Biodesign Offerings  Stanford-India Biodesign Fellowships (Begun)  India Biodesign Internships at AIIMS/IIT Delhi (Begun)  Medical Device Innovation courses to be offered across India (2010)  Core Stanford Biodesign innovation lectures to be offered online (Begun)  Global student/faculty exchanges (Begun)  National Indian Med Tech summit (Begun)  Support of nationwide innovation contests (Begun)  Creation of SIB Centers – 2008: First SIB Center in New Delhi (Begun)  www.indiabiodesign.org networking community (Begun) 12
  • 13. Stanford-India Biodesign Fellowships  1-2 year fellowships housed at Stanford and New Delhi  Interdisciplinary, team-based learning combining engineering, clinical and business trainees  Intensive exposure to medical needs-finding within the Indian setting  Teams invent, develop, patent and commercialize technologies  Mentoring by world class faculty at Stanford, IIT Delhi and AIIMS  Mentoring by “real world” industry experts and advisors in the US and India – Technology innovators, legal, venture capital 13
  • 14. Fellowship Selection Process  300 worldwide applicants (Indian citizens)  17 Semi-finalists interviewed in New Delhi  8 Finalists interviewed at Stanford  5 Fellows selected 14
  • 15. 2008 Fellows  Nishith Chasmawala – Johnson & Johnson, Medtronic  Srinivas Jaggu – Kirloskar, General Electric  Jayant Karve – General Electric  Amit Sharma – IIT Delhi  Sandeep Singh, MD – Associate Professor of Cardiology, AIIMS  New Fellows arrived January 2009 – Includes 2 Professors from IIT Madras, IIT Delhi 15
  • 17. Post-Fellowship Activities  Track 1 – Start med tech company in India  Track 2 – Join multinational or other established med tech company – Pursue “intrapreneurial” activities  Track 3 – Return to academia – Teach Biodesign fundamentals in India All fellows are expected to remain in India and maintain a mentoring relationship with SIB 17
  • 18. Indian Biodesign Internships at AIIMS/IIT Delhi  3-6 month concentrated exposure at AIIMS/IIT Delhi  Goal is to get (less complicated) products to market quickly  Teaching staff to include Fellows, Professors at AIIMS, IIT  Interns to include engineering students and engineers/business people from industry  Began October 2008 18
  • 19. Medical Device Innovation Course at Multiple Indian Universities  To be broadly deployed at top engineering institutions in India  Based on similar Medical Device Design course at Stanford  Customized for India  Can accommodate ~30 undergraduate and graduate students  Part didactic, part project (prototyping)  Core lectures designed by Stanford-India Biodesign  Projects led by practicing physicians – 3-4 students per team 19
  • 20. First Annual Indian Med Tech Summit 20
  • 21. First Stanford-India Biodesign Centre (AIIMS—New Delhi) 21
  • 22. Support of National Med Tech Innovation Contest Through IIT Bombay 22
  • 24. Potential Benefit for India  Greatly increased exposure to medical technology innovation at university level to significantly increase graduates with interests in medical technology careers  Development of academic faculty capable of training dozens of future med tech leaders per year  Development of industry leaders capable of leading entrepreneurial or “intrapreneurial” initiatives  Development of New Delhi (and second location TBD) to serve as hubs of medical technology innovation  Development of an ecosystem that is sorely lacking  Matching of job applicants with employers  Devices made expressly for the needs of Indians and others in developing countries 24
  • 25. Getting Involved  Advisors and mentors still needed  Funding needed to scale program – Corporates – VCs – Foundations – Individuals  If interested, please email me at rdoshi@stanford.edu We need the community’s help to achieve the greatest impact 25