Shanghai University

Research: thoughts on a personal experience. Dany Morisset [email_address] http://www.nib.si/en/

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Where is Slovenia? Shanghai Slovenia

Italy Germany Venezzia (Venice)

Slovenia (Slovenija) GENERAL INFORMATION Area: ............. ............. 20,273 km2 (80km x 260 km) 7,037km2 for Shanghai (city) Forest: .......... ............. 10,124 km2 (49.9%) Vineyards: ......... ......... 216 km2 Length of coast:..........46.6 km Capital: ........... ........... Ljubljana Population: ........ ... .....2 ,023,000 (2008) 18,450,000 in Shanghai (2007) Language: ........ ........ .Slovene Currency: ....... ....... ....Euro, 1 January 2007 Education: ........... ...... Universities in Ljubljana , Nova Gorica and Maribor cca 90,000 students

Triglav, the highest Slovenian mountain Bled, jewel of the Julian Alps Ljubljana, the capital city Rafting on the Soča River

Piran, Tartini’s coastal town Piran bay Julian Alps

Postojna Cave Lipica horses Proteus anguinus or human fish Karstic land in Škocjan park

Vineyard from Štajerska Region Slovenian specialities Slovenian wine producing

National Institute of Biology at the Biological Centre in Ljubljana Italy Germany Venezzia (Venice)

NIB is the leading institution for basic and applied research in biological sciences in Slovenia… and… the third largest institution in the field of natural sciences in Slovenia!

Mission NIB is a public research institute, established by the Republic of Slovenia with the mission: - to create new (basic) knowledge on the field of biology and related natural sciences; - to transfer new knowledge into use for improvement of the quality of life (to enrich the life on Earth).

National Institute of Biology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Department of Biotechnology and Systems Biology ,[object Object],[object Object],[object Object],[object Object],Pr. Dr Maja Ravnikar

- Horizontal project organisation: - OMICS (Kristina Gruden) - MICROBIOLOGY (Maja Ravnikar) - GENETICALY MODIFIED ORGANISMS (Jana Žel) - Infrastructure (Maruša Pompe Novak) - Quality Assurance and lab safety issues (Marjana Camloh) - Human resources and pedagogical activities (Maja Kovač, Marina Dermastia) - Bio-security (Mojca Milavec) Activities

Projects ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

International cooperation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

OMICS: Systems biology approaches Methodologies ,[object Object],[object Object],[object Object],[object Object],[object Object]

OMICS: Systems biology approaches ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Biological problems :

MICROBIOLOGY ,[object Object],[object Object],[object Object]

Real time RT- PCR: PVY NTN - distinction of strains CSNV, TSWV, INSV ToMV (CIM), CaMV (CIM), PePMV - distinction of strains, Rotaviruses – water samples Xylophyllus ampelinus , Eam, Phytoplasmas Microarray technology, ring trial New Methods: Development of sensitive methods for plant pathogen detection

Concentration and purification of plant viruses ,[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],Genetically Modified Organisms (GMOs):

[object Object],[object Object],Transgenic plants

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Research and development, projects

GMOs diagnostics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

National Reference laboratory ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Studies, PhD ,[object Object],[object Object],[object Object],[object Object],[object Object],Poitiers University, France

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First postdoc Postdoctoral studies in University Laval and Hospital Laval, Quebec city, Qc, Canada ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Neutrophil inhibitors PDE4 inhibitors Alveolar repair Mucoregulators Immunosuppressants? Protease inhibitors AAT, SLPI, pre-elafin, TIMPs Mediator antagonists LTB 4 inhibitors Chemokine antagonists Quit smoking Emphysema Mucus hypersecretion PROTEASES Neutrophil elastase Cathepsins MMPs Neutrophil Alveolar macrophage CD8 + lymphocyte Chemotactic mediators (IL-8, LTB 4 ) MCP-1 ?

Actual work ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Traceability issues ,[object Object],[object Object],[object Object],[object Object]

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Relation with authorities ,[object Object],[object Object],[object Object],[object Object],NATIONAL INSTITUTE OF BIOLOGY Ministry of Health Ministry of Environment and Spatial Planning Ministry of Agriculture, Forestry and Food Inspectorate for Agriculture, Forestry and Food Inspectorate for the Environment and Spatial Planning Health Inspectorate Ministry of Defence and Slovenian Research Agency

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National Reference laboratory ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Conclusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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