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Oral Mucous Membrane
UploadUpload By : Ahmed Ali AbbasBy : Ahmed Ali Abbas
Babylon University College of DentistryBabylon University College of Dentistry
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1.Oral Mucosa
The moist lining of the oral cavity is called Oral
Mucosa or Oral Mucous Membrane
The function of oral mucosa is protection,
sensation and secretion
It is continuous with the skin outside the oral
cavity and differs from it in appearance and
structure
Oral Mucous Membrane
Oral Mucous Membrane
Epithelium
Lamina Propria
Submucosa
Periosteum
Bone
Oral Epithelium
Oral epithelium forms the surface of the oral mucosa
that forms a barrier between the oral environment
and the deeper tissues
It is derived from the embryonic ectoderm
It is stratified squamous epithelium and may or may
not be keratinized
Beneath the epithelium lies the connective tissue
Oral Epithelium
-Keratinized
CELL LAYERS OF ORTHOKERATINISED
EPITHELIUM
KERATINIZED EPITHELIUM
Keratinized oral epithelium
Most of theoral mucosal surfaceislined by nonkeratinized stratified
squamous epithelium except gingiva, hard palate and dorsal surface
of thetonguewheretheepithelium iskeratinized
The keratinized cells have no nuclei and the cytoplasm is displaced
by largenumbersof keratin filaments
Keratinized epithelium is associated with masticatory function and
havefour layersof cells
Thefour layersare:
1.Stratum Basale
2.Stratum Spinosum
3.Stratum Granulosum
4.Stratum Corneum
Cellular layers of oral epithelium - Keratinized
1. Stratum Basale
The cells of the stratum basale are cuboidal or low columnar and
form asinglelayer resting on thebasal lamina
The basal lamina is at the interface of the epithelium and lamina
propria
Epithelial cellsof theoral mucosaarein aconstant stateof renewal
Thebasal cellsshow themaximum mitotic activity
2. Stratum Spinosum
Stratum spinosum isusually several cellsthick
They shaped likepolyhedron with short cytoplasmic processes
The stratum basale and the first layers of stratum spinosum are
referred to as stratum germinativum because these cells give rise
to new epithelial cells
3. Stratum Granulosum
Cells of stratum granulosum are flat and are found in layers of three
to fivecellsthick
This layer is prominent in keratinized epithelium (and absent in
nonkeratinized epithelium)
Thesecellshavekeratohyalinegranulesin their cytoplasm
Keratohyaline granules help to form the matrix of the keratin fibres
found in thesuperficial layer
4. Stratum Corneum
Cellsof stratum corneum areflat, devoid of nuclei and full of keratin
filament surrounded by amatrix
These cells are continuously being sloughed and are replaced by
epithelial cellsthat migratefrom theunderlying layers
Nonkeratinized oral epithelium
Nonkeratinized epithelial cells in the superfecial layers do not have
keratin filamentsin thecytoplasm
Thesurfacecellsalso havenuclei
Thestratum corneum and stratum granulosum layersareabsent
Thisepithelium isassociated with lining of theoral cavity
NON KERATINIZED EPITHELIUM
LAMINA PROPORIA
LAMINA PROPORIA
Connective tissue
Connective tissue can be differentiated as Lamina Propria and
Submucosa
Lamina propria
Lamina propria is the connective tissue layer immediately below the
epithelium
It can bedivided into papillary layer and thereticular layer
Papillary layer forms finger like projections of connective tissue that
extend deep in theepithelial layers
Papillary layer is prominent in masticatory mucosa and reticular
layer isprominent in lining mucosa
Lamina prorpria consists of blood vessels and cells like fibroblasts,
cellsof blood vesselsand lymphaticsand nerves
Epithelium is avascular, hence its metabolic needs come via the
vesselsof thelaminapropria
Submucosa
Submucosa lies below the lamina propria and serves as an
attachment between laminapropriaand boneor skeletal muscle
It isfound in thecheeks, lipsand partsof thepalate
It consists of large blood vessels, nerves and lymphatics and its
functionsarenutrition and defense
2. Functional types of Oral Mucosa
Lining mucosa and Masticatory mucosa
Lining mucosa
Lining mucosa covers all soft tissue of the oral cavity except the
gingiva, hard palateand thedorsal surfaceof thetongue
Lip
Lip iscovered by lining mucosa
Lip with skin on outer surface and
lining mucosa on inner surface
Vermilion border
The junction between the skin and mucous membrane is known as
thevermilion border
Here the epithelium is thin therefore, the red blood cells in the
capillariesshow through contributing to thevermilion colour
Vermelion Zone
VERMILLION BORDER OF LIP
Ventral surface of the tongue
Thelining mucosa here contains both lamina propria and submucosa
The submucosa merges with the muscle bundles of the ventral
surfaceof thetongue
Ventral surface of tongue
HARD PALATE
SOFT PALATE
Cheek
In the cheek the underlying submucosa contains fat cells and small
mixed salivary glands
Cheek
Floor of the mouth
The mucous membrane of the floor of the mouth is thin and loosely
attached to theunderlying structures
Floor of the mouth
Masticatory mucosa
Masticatory mucosacoversthegingivaand hard palate
In edentulous mouth, masticatory mucosa covers the chewing
surfaceof thedental arches
Gingiva
Gingiva has keratinized or parakeratinzed epithelium with no
submucosal layer
It develops from the union of oral epithelium and reduced enamel
epithelium of thedeveloping tooth
Gingiva can be classified as free gingiva, attached gingiva and
interdental papilla
Normal Gingiva
Development of gingiva from oral epithelium and reduced enamel epithelium
Anatomy of gingiva
Free gingiva (or marginal gingiva)
It is that part of the oral mucosathat surrounds the necksof theteeth
and formsthefreemargin of thegingival tissue
It is differentiated apically from the attached gingival by the free
gingival groove
Theinner sideof it formsthegingival sulcus
The free gingival mucosa is composed of stratified squamous
epithelium that may be keratinized, parakeratinzed or sometimes
nonkeratinized
Free gingiva
A- gingiva
B- sulcular
epithelium
C- junctional
epithelium
D- lamina
propria
(connective
tissue)
E- alveolar
process
F- PDL
Alveolar Mucosa (Arrows - Interdental Papillae)
Attached gingiva
The attached gingiva lies between the free gingival groove and the
alveolar mucosa
The junction of the attached gingiva and the alveolar mucosa is
called mucogingival junction
In healthy mouth attached gingiva shows stippling (orange-peel
appearance) which isacharacteristic of thistypeof mucosa
Histology of gingiva
Mucogingival junction (arrows)
Alveolar Mucosa
Interdental papilla
Interdental papillae are those parts of gingival tissue that appear in-
between teeth apical to thecontact points
Interdental grooves extend vertically between the interdental papilla
corresponding to thedepressionsbetween theroots
Confirming to the shape of the interproximal contact area is a valley
likedepression in theinterdental papillacalled Col.
Thisdepression liesin thefacial and lingual plane
Interdental Papilla (arrow)
Diagram of positional relation of col in health
and disease for canine, premolar and molar
Col accentuated during inflammation (arrows)
Junctional epithelium
Junctional epithelium forms the seal of the gingival epithelium and
thetooth
It forms the floor of the gingival sulcus and extends apically to the
enamel of thetooth
Disturbances of epithelial attachment results in deepening of the
sulcuswhich isasign of gingival/periodontal disease
Histology of gingiva
GINGIVA
TYPES OF EPIFHELIUM:
Oral or outer epithelium
sulcular epithelium
Junctional epithelium
Sulcular epithelium
Junction epithelium
Oral epithelium
HISTOLOGY OF GINGIVA
GINGIVAL EPITHELIUM
Hard palate
The surface of the hard palate that is visible in the mouth is covered
by masticatory mucosa
Thelateral regionsof theposterior part contains palatineglands
Theseglandsarepurely mucousglands
The midline of the hard palate is called median raphe where there is
no submucosa
A seriesof foldsappear in theanterior part of thepalatecalled rugae
Dr.SyedSadatullah
KingKhalidUniversity
Hard Palate and Soft Palate
3 Mucosa of the Tongue
Specialized mucosa covers the dorsal surface of the body of the
tongue
The connective tissue binds the epithelium to the underlying skeletal
muscle
The epithelium is modified, keratinized, stratified covered with
papillae, which can beseen by naked eye
Thedifferent papillaefound on thedorsal surfaceof thetongueare:
1.Filliform papillae
2.Funginform papillae
3.Circumvallate papillae
4.Foliate papillae
Dorsum of Tongue
Cross section of tongue
1. Filliform papillae
Filliform papillae are pointed extensions of the keratinized epithelial
cells
They arethemost numerouspapillaeof thetongue
They arenot associated with tastebuds
Scanning electron micrograph of
Filliform papillae(arrow)
Filliform Papillae
2. Fungiform papillae
Fungiform papillae are fewer than the filliform papillae and are
scattered over thedorsal surfaceof thetongue
They arerounded elevationsabovethesurfaceof thetongue
They havetastebudson their superior surfaces
Thesurfaceof fungiform papillaeisnot keratinized
Scanning electron micrograph of Fungiform
papillae (arrow) surrounded by Filliform papillae
Fungiform Papillae
3. Circumvallate papillae
The circumvallate papillae are located at the junction of the anterior
two thirds(body) and posterior onethirds(base) of thetongue
There are eight to twelve in number and are bigger than fungiform
papillae
Circumvallatepapillaearelined with tastebudsand also openingsof
serousglands
The secretion from the serous glands washes away food for renewal
of taste
Circumvallate Papilla and Taste buds (arrows)
4. Foliate papillae
Foliate papillae are located in the furrows along the posterior sides
of thetongue
They may belined with tastebuds
They arenot prominent in human beings
TONGUE
PAPILLAE OF TONGUE
FILIFORM PAPILLAE
FUNGIFORM & CIRCUMVALLATE
TASTE BUDS
TASTE BUDS
TASTE PORES
Thank You

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Oral mucous membrane

  • 1. Oral Mucous Membrane UploadUpload By : Ahmed Ali AbbasBy : Ahmed Ali Abbas Babylon University College of DentistryBabylon University College of Dentistry downloaddownload this file from Website onthis file from Website on GoogleGoogle TheOptimalSmile.wix.comTheOptimalSmile.wix.com Then choose LecturesThen choose Lectures Then Second StageThen Second Stage Then choose the lecture you needThen choose the lecture you need
  • 2. 1.Oral Mucosa The moist lining of the oral cavity is called Oral Mucosa or Oral Mucous Membrane The function of oral mucosa is protection, sensation and secretion It is continuous with the skin outside the oral cavity and differs from it in appearance and structure
  • 4. Oral Mucous Membrane Epithelium Lamina Propria Submucosa Periosteum Bone
  • 5.
  • 6. Oral Epithelium Oral epithelium forms the surface of the oral mucosa that forms a barrier between the oral environment and the deeper tissues It is derived from the embryonic ectoderm It is stratified squamous epithelium and may or may not be keratinized Beneath the epithelium lies the connective tissue
  • 8. CELL LAYERS OF ORTHOKERATINISED EPITHELIUM
  • 10. Keratinized oral epithelium Most of theoral mucosal surfaceislined by nonkeratinized stratified squamous epithelium except gingiva, hard palate and dorsal surface of thetonguewheretheepithelium iskeratinized The keratinized cells have no nuclei and the cytoplasm is displaced by largenumbersof keratin filaments Keratinized epithelium is associated with masticatory function and havefour layersof cells
  • 11. Thefour layersare: 1.Stratum Basale 2.Stratum Spinosum 3.Stratum Granulosum 4.Stratum Corneum Cellular layers of oral epithelium - Keratinized
  • 12. 1. Stratum Basale The cells of the stratum basale are cuboidal or low columnar and form asinglelayer resting on thebasal lamina The basal lamina is at the interface of the epithelium and lamina propria Epithelial cellsof theoral mucosaarein aconstant stateof renewal Thebasal cellsshow themaximum mitotic activity
  • 13. 2. Stratum Spinosum Stratum spinosum isusually several cellsthick They shaped likepolyhedron with short cytoplasmic processes The stratum basale and the first layers of stratum spinosum are referred to as stratum germinativum because these cells give rise to new epithelial cells
  • 14. 3. Stratum Granulosum Cells of stratum granulosum are flat and are found in layers of three to fivecellsthick This layer is prominent in keratinized epithelium (and absent in nonkeratinized epithelium) Thesecellshavekeratohyalinegranulesin their cytoplasm Keratohyaline granules help to form the matrix of the keratin fibres found in thesuperficial layer
  • 15. 4. Stratum Corneum Cellsof stratum corneum areflat, devoid of nuclei and full of keratin filament surrounded by amatrix These cells are continuously being sloughed and are replaced by epithelial cellsthat migratefrom theunderlying layers
  • 16. Nonkeratinized oral epithelium Nonkeratinized epithelial cells in the superfecial layers do not have keratin filamentsin thecytoplasm Thesurfacecellsalso havenuclei Thestratum corneum and stratum granulosum layersareabsent Thisepithelium isassociated with lining of theoral cavity
  • 20. Connective tissue Connective tissue can be differentiated as Lamina Propria and Submucosa Lamina propria Lamina propria is the connective tissue layer immediately below the epithelium It can bedivided into papillary layer and thereticular layer Papillary layer forms finger like projections of connective tissue that extend deep in theepithelial layers
  • 21. Papillary layer is prominent in masticatory mucosa and reticular layer isprominent in lining mucosa Lamina prorpria consists of blood vessels and cells like fibroblasts, cellsof blood vesselsand lymphaticsand nerves Epithelium is avascular, hence its metabolic needs come via the vesselsof thelaminapropria
  • 22. Submucosa Submucosa lies below the lamina propria and serves as an attachment between laminapropriaand boneor skeletal muscle It isfound in thecheeks, lipsand partsof thepalate It consists of large blood vessels, nerves and lymphatics and its functionsarenutrition and defense
  • 23. 2. Functional types of Oral Mucosa Lining mucosa and Masticatory mucosa Lining mucosa Lining mucosa covers all soft tissue of the oral cavity except the gingiva, hard palateand thedorsal surfaceof thetongue Lip Lip iscovered by lining mucosa Lip with skin on outer surface and lining mucosa on inner surface
  • 24. Vermilion border The junction between the skin and mucous membrane is known as thevermilion border Here the epithelium is thin therefore, the red blood cells in the capillariesshow through contributing to thevermilion colour Vermelion Zone
  • 26. Ventral surface of the tongue Thelining mucosa here contains both lamina propria and submucosa The submucosa merges with the muscle bundles of the ventral surfaceof thetongue Ventral surface of tongue
  • 29. Cheek In the cheek the underlying submucosa contains fat cells and small mixed salivary glands Cheek
  • 30. Floor of the mouth The mucous membrane of the floor of the mouth is thin and loosely attached to theunderlying structures Floor of the mouth
  • 31. Masticatory mucosa Masticatory mucosacoversthegingivaand hard palate In edentulous mouth, masticatory mucosa covers the chewing surfaceof thedental arches Gingiva Gingiva has keratinized or parakeratinzed epithelium with no submucosal layer It develops from the union of oral epithelium and reduced enamel epithelium of thedeveloping tooth Gingiva can be classified as free gingiva, attached gingiva and interdental papilla
  • 33. Development of gingiva from oral epithelium and reduced enamel epithelium
  • 35. Free gingiva (or marginal gingiva) It is that part of the oral mucosathat surrounds the necksof theteeth and formsthefreemargin of thegingival tissue It is differentiated apically from the attached gingival by the free gingival groove Theinner sideof it formsthegingival sulcus The free gingival mucosa is composed of stratified squamous epithelium that may be keratinized, parakeratinzed or sometimes nonkeratinized
  • 37. A- gingiva B- sulcular epithelium C- junctional epithelium D- lamina propria (connective tissue) E- alveolar process F- PDL
  • 38. Alveolar Mucosa (Arrows - Interdental Papillae)
  • 39. Attached gingiva The attached gingiva lies between the free gingival groove and the alveolar mucosa The junction of the attached gingiva and the alveolar mucosa is called mucogingival junction In healthy mouth attached gingiva shows stippling (orange-peel appearance) which isacharacteristic of thistypeof mucosa
  • 43. Interdental papilla Interdental papillae are those parts of gingival tissue that appear in- between teeth apical to thecontact points Interdental grooves extend vertically between the interdental papilla corresponding to thedepressionsbetween theroots Confirming to the shape of the interproximal contact area is a valley likedepression in theinterdental papillacalled Col. Thisdepression liesin thefacial and lingual plane
  • 45. Diagram of positional relation of col in health and disease for canine, premolar and molar Col accentuated during inflammation (arrows)
  • 46. Junctional epithelium Junctional epithelium forms the seal of the gingival epithelium and thetooth It forms the floor of the gingival sulcus and extends apically to the enamel of thetooth Disturbances of epithelial attachment results in deepening of the sulcuswhich isasign of gingival/periodontal disease
  • 49. TYPES OF EPIFHELIUM: Oral or outer epithelium sulcular epithelium Junctional epithelium Sulcular epithelium Junction epithelium Oral epithelium
  • 52. Hard palate The surface of the hard palate that is visible in the mouth is covered by masticatory mucosa Thelateral regionsof theposterior part contains palatineglands Theseglandsarepurely mucousglands The midline of the hard palate is called median raphe where there is no submucosa A seriesof foldsappear in theanterior part of thepalatecalled rugae
  • 54. 3 Mucosa of the Tongue Specialized mucosa covers the dorsal surface of the body of the tongue The connective tissue binds the epithelium to the underlying skeletal muscle The epithelium is modified, keratinized, stratified covered with papillae, which can beseen by naked eye
  • 55. Thedifferent papillaefound on thedorsal surfaceof thetongueare: 1.Filliform papillae 2.Funginform papillae 3.Circumvallate papillae 4.Foliate papillae Dorsum of Tongue
  • 57. 1. Filliform papillae Filliform papillae are pointed extensions of the keratinized epithelial cells They arethemost numerouspapillaeof thetongue They arenot associated with tastebuds Scanning electron micrograph of Filliform papillae(arrow)
  • 59. 2. Fungiform papillae Fungiform papillae are fewer than the filliform papillae and are scattered over thedorsal surfaceof thetongue They arerounded elevationsabovethesurfaceof thetongue They havetastebudson their superior surfaces Thesurfaceof fungiform papillaeisnot keratinized
  • 60. Scanning electron micrograph of Fungiform papillae (arrow) surrounded by Filliform papillae
  • 62. 3. Circumvallate papillae The circumvallate papillae are located at the junction of the anterior two thirds(body) and posterior onethirds(base) of thetongue There are eight to twelve in number and are bigger than fungiform papillae Circumvallatepapillaearelined with tastebudsand also openingsof serousglands The secretion from the serous glands washes away food for renewal of taste
  • 63. Circumvallate Papilla and Taste buds (arrows)
  • 64. 4. Foliate papillae Foliate papillae are located in the furrows along the posterior sides of thetongue They may belined with tastebuds They arenot prominent in human beings