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Vision Opportunities
in Healthcare
December, 2019
Rudy Burger
Vini Jolly
2
Introduction to WCP
AutoTech Report
▪ M&A, strategic partnerships, and corporate finance advisory
▪ Focused on emerging growth technology companies
▪ Founded in 2001: over $8 billion in transaction value
▪ Offices in Silicon Valley, London, Shanghai
▪ Dedicated Digital Health and Computer Vision corporate
finance practice
Digital Health Artificial Intelligence
Collaborative Robots
Embedded Vision / Visual AI Market Map
Camera
Modules
Sensors Illumination Lenses
Cameras Processors
Boards and
Modules
Processors
and SoCs
SoftwareMemory
Enabling
Services & Tools
Development
Tools
Image & Video
Data
Standards
Components
Subsystems
Open SourceDesign &
Manufacturing
Services
Silicon IP
Automotive
Tier 1
Suppliers
Consumer
RetailTransportation
Industrial Security &
Surveillance
Defense &
Aerospace
Communication Media &
Entertainment
Agriculture
Healthcare
EnablingTechnologiesSystems&Solutions
3
Market Size – US Health Spending
United States, 1967 to 2017, Selected Years, and 10-year Projection
4
$52 $174
$517
$1,135
$2,295
$3,492
$5,963
$0
$1,000
$2,000
$3,000
$4,000
$5,000
$6,000
$7,000
1967 1977 1987 1997 2007 2017 2027P
Billions
Source: CMS.gov
5
Market Size – US Healthcare Spending Per Capita (’00 - ’18)
4.6k
4.9k
5.3k
5.7k
6.1k
6.4k
6.8k
7.2k
7.4k
7.7k
7.9k
8.2k
8.4k
8.6k
9.0k
9.5k
9.9k
10.2k
10.6k
$0k
$2k
$4k
$6k
$8k
$10k
$12k
2000 2002 2004 2006 2008 2010 2012 2014 2016 2018
Source: CMS.gov
US Healthcare Spending by Type of Product/Service
33%
20%9%
5%
5%
4%
3%
3%
2%
2%
14%
Hospital Care
Physician and Clinical Services
Retail Prescription Drugs
Other Health, Residential and Personal
Care Services
Nursing Care Facilities and Continuing
Care Retirement Communities
Dental Services
Home Health Care
Other Professional Services
Other Non-Durable Medical Products
Durable Medical Equipment
OthersTotal Spending: USD3.65 tn
6Source: CMS.gov
US Healthcare Spending – Key Facts
Total spending on
healthcare by
Americans in 2018
USD3.65 tn
Growth in spending
over 2017
4.4%
Estimated growth in
spending during
2018 - 2027
5.5%
Spending per person
USD11,212
Spending goes to
hospitals, doctors,
and clinical services
GDP share related to
healthcare spending
17.7%59%
Of all medical
spending goes to
waste
25%
Number of deaths
due to misdiagnosis
40,000 – 80,000
7Source: CMS.gov
Benefits of Computer Vision in Healthcare
• More accurate diagnoses of
medical image data
• Reduce redundant surgical
procedures and expensive
therapies
• Detect the slightest presence of a
condition
Precise Diagnoses
• Many fatal illnesses need to be
diagnosed in their early stages.
CV enables the early detection
of symptoms leading to timely
treatment and increased
probability of survival
Timely Detection of
Illness
• The use of CV in healthcare can
lessen the time doctors take in
analyzing reports and images – thus
giving them more time to spend
with patients and provide
personalized and constructive
advice
Improved Patient
Care
• CV technology enables doctors to
remotely monitor and analyze
health and fitness metrics to
assist patients to make faster and
better medical decisions
Health
Monitoring
• CV enables
pharmaceutical
companies to
significantly increase
throughput
Reduce Drug
Development Costs
8
9
Computer Vision in Healthcare Applications
Source: Health Tech Magazine
• Facial/Feature analytics
• Pharma/Clinical Trial
adherence
• Child/Crib monitoring
• Physical Therapy
• Pain Management
Remote Monitoring, Care & Adherence
• AR/VR/Mixed Reality
Training across
domains
• Remote Surgical
Applications
• Growing application list
(Cardio, Lung, Hernia)
Remote/Robotic Surgery/Training
Drug Discovery
• Visualization
• High Throughput
Molecular/Target
simulations
• Cellular Level Analysis
Medical Imaging/Diagnostics
• Radiology (MRI/CT/X-
ray)
• Pathology (Biopsies)
• Oncology
• Dermatology
• Opthalmology
• Cardiology (3D
imaging)
• Neurology (Strokes,
Brain scans)
• Lab Diagnostics
• Genomics
10
Healthcare Computer Vision Market Map
Source: CB Insights, News Releases, Pitchbook
Imaging & Diagnostics Drug Discovery
Remote/Patient Monitoring
Virtual Assistant
Clinical Trials Nutrition
Compliance
Mental Health
Genomics
Fitness
Wearables
3,500
2,625
1,750
875
0
11Source: Tractica
$Millions
2017 2018 2019 2020 2021 2022 2023 2024 2025 2026
Medical Imaging & Diagnostics
Clinical trials
Surgeries
Other Application
Patient management and Research
$200M
$3,450.3M
CAGR 42.8%
Global Computer Vision in Healthcare Market by Application
$1.0 $1.0 $7.9
$27.3 $22.2 $26.7
$139.4
$217.9
$492.9
1 1 6 7 9 12 12
24 26
2011 2012 2013 2014 2015 2016 2017 2018 2019
Funding ($M) # of Deals
Computer Vision in Healthcare Venture Funding
Source: Pitchbook 12
Bringing AI and Deep Learning to pathology to automate rapid and accurate diagnoses
AI for radiology (CT and X-ray) to detect abnormalities and speed time to diagnoses for
everything from bone density to cranial bleeding
AI and Cloud Supercomputing for fast, accurate image analysis especially for
cardiovascular and lung conditions
Brings affordable, scalable and accurate blood diagnostics to the point-of-care, thereby
accelerating better patient outcomes and improving healthcare for all
Visualization & Deep Learning for drug discovery
Securely stream patient photographs and wound analysis directly to your desktop
Designer of a medical imaging device that reduces the cost of real-time and 3D imaging
and treatment
Non-invasive coronary artery disease detection using 3D image rendering
Machine vision based facial analysis to identify patient adherence
Machine vision to analyze movement and falls for patients/seniors
Using computer vision for remote health monitoring
Cutting Edge Computer Vision Healthcare Companies
13Source: Crunchbase
14
Centralized vs. Remote Data Acquisition
Source: Company Websites, Secondary Research
Lab Diagnostic Cardiology DNA Testing MRI CT ScanUltrasound
Centralized Data Acquisition & Analytics
Opthalmology DermatologyCrib Cam Lab Diagnostics
Remote
Monitoring Bio-monitoring
Point of Care/Remote Data Acquisition & Analytics
Best Funded Companies in Computer Vision Healthcare
Company Name Deal Date
Company
Stage
Overview
Recent
Funding ($M)
Pre-money
Valuation ($M)
Tempus, United States 5/30/2019 Series F Developer of a health care data analytics platform designed to improve patient
outcomes.
$200.00 $3,100.00
PathAI, United States 4/17/2019 Series B Developer of an AI-powered research platform intended to improve the accuracy and
efficiency of cancer diagnosis and treatment.
$60.00
-
Healthy.io, Israel 9/11/2019 Series C The company's computer vision and artificial intelligence algorithms based platform
captures test strip images using smartphone camera, analyze chemical color of urine
test strips and give instant reports.
$60.00
-
ImagenTechnologies,
United States
9/12/2018 Series B Developer of a medical diagnostic technology designed to offer medical imaging services
to reduce diagnostic errors and improve patient outcomes.
$41.00 $75.00
Paige.ai, United States 11/27/2019 Series B Developer of computational pathology modules intended for rapid diagnostic
stratification, cancer detection, tumor segmentation, prediction of treatment response
and overall survival.
$33.69 $208.69
Arterys, United States 11/3/2017 Series B Developer of a medical imaging analytics platform designed to offer improved patient
care.
$30.60 $52.00
OrCam, Israel 2/20/2018 Provider of a portable artificial vision device designed to help the visually impaired
understand text and identify objects easily.
$30.40 $1,000.00
Sight Diagnostics, Israel 2/14/2019 Series B Developer of automated microscopy device designed to improve healthcare for
everyone through smarter blood testing.
$27.80
-
AiCure, United States 11/7/2019 Series C Provider of an intelligent medical assistant services designed to leverage a visual
recognition platform to monitor patient progress.
$24.50
-
Gauss Surgical, United
States
10/17/2018 Series C The company leverages computer vision and machine learning to deliver mobile
applications for the operating room, with a focus on improving patient safety, quality
and outcomes.
$20.00 $75.00
15
16
Key Portfolio Companies of Major Investors
Source: 3DS, Medical Device Network, Francisco Partners, WellSoft, Point Click Care, Secondary Research
Investors Key Portfolio Companies
Khosla Ventures HealthTap, Zebra Medical Vision, Curai, Arpeggio Bioscience, Olive (RPA)
DCVC Zymergen, Culture Bioscience, CloudMedx, ProteinQure, HumanDx
Andreessen Horowitz TwoAR, Freenome
Google Ventures
Flatiron, Insitro, Verana Health, Owkin, Fathom (Medical Coding Automation), DxOptics,
ImagenTechnologies, Recursion Pharmaceuticals, Atomwise
General Catalyst
Mindstrong Health, OM 1, Curai, Imprivata, Color, Roman Health, Avant-Grade Health, Aidin,
Humedica, Prematics
General Atlantic
Change Healthcare, EviCore Healthcare, Eclipsys, MultiPlan, Envoy, Amedes Group, CitrusTech,
Change Healthcare, Alignment Healthcare, Capario, OneOncology, eRx Network, MedUnite,
Healthcare Technology Management Services, MeDIStar Group
Polaris
OM 1, Gauss Surgical, Imprivata, Phytel, Phreesia, Free & Clear, Quartet Health, Partsource,
Perpetual Motion, Prospex Medical, Sentillion, Strata Health Solutions, Wellsphare
Digitix Savonix, Tissue Analytics, Siris Medical, WellDoc
Canaan
Abyrx, Ambra, Anliva Biosciences, Arrakis Therapeutics, Arvinas, Corvium, Genome Medical, Glooko,
Roman, Truveris, Vineti
Bessemer Ventures
AccuVein, Artemis Health, Bright Health, Collective Medical, Docent Health, Fractyl, Groups, Kymera
Therapeutics, Nym, Qventus, Subtle Medical, TScan Therapeutics
Big Tech Transforming Healthcare (1/2)
Large data companies like Google, Amazon and Apple are making huge strides into healthcare as
technological advancements have enabled digital healthcare to advance rapidly
• Most active big tech firm in
healthcare AI initiatives
• Founded Verily in 2015
• Project Medical Digital Assist
focused on AI usage in
physician assistance
• Developed algorithm to
diagnose diabetic
retinopathy in images
• Acquired fitness activity
tracker Fitbit for $2.1 billion
• Partnered with biotech firms
C4 Therapeutics and AbbVie
pharmaceuticals via Calico
• Corporate healthcare system
– Amazon Care
• Purchased online pharmacy
startup PillPack
• Plans to sell medical records
reading software
• Working on cancer research
and other healthcare related
ventures such as last-mile
delivery
• Focus on patient facing
products as well as
streamlining medical
payments
• Received FDA clearance for
new heart monitoring Apple
Watch feature (EKG)
• Implementing Apple Health
Records system through
hospital partnerships
• Acquired sleep monitor
company Beddit (May 2017)
and personal health data
platform Gliimpse (2016)
17
Big Tech Transforming Healthcare (2/2)
The healthcare industry presents tremendous business opportunity, encouraging other top tech
companies to adopt healthcare innovation
• Launched health care division
in 2017 that focuses on AI for
patient care improvement
• Alliance with Walgreens to
develop new health care
innovations
• Offering healthcare focused
solutions through Azure suite
• Collaborative research on
applying AI to MRI scans
• Acquires neural interface
startup CTRL-Labs for its mind-
reading wristband
• Plans to launch “Preventive
Health” tool to prompt users
to get regular checkups
• Acquired predictive healthcare
technology business of
BioSensics
• Bought seniors-focused health
services company Critical
Signal Technologies and
GreatCall, emergency
concierge & monitoring
services provider
• Acquired Auris Health’s robotic
platform technology used in
diagnostic and lung therapeutic
procedures
• Partnered with accelerator
Founders Factory with focus on
startups in the consumer
healthcare space
• Intel Capital invested in
Lumiata, which improves
quality of hospital care through
data and predictive analytics
• Invested in EchoPixel, which is
developing tools to enable
non-invasive colon cancer
screening
• Launched Uber Health: non-
medical-emergency
transportation service
18
FDA Gears for Innovation in Medical Technology
As shift towards new technologies gains momentum, the FDA has worked to modernize their
regulatory approach to facilitate innovation to improve the healthcare system:
Proposed regulatory
framework for dynamic AI
systems to ensure realization
of the full potential of the
technology
Approval of 106 novel
devices in 2018, including
artificial intelligence based
technologies for diabetic
retinopathy diagnosis
Creation of a Center for
Excellence for Digital Health
to complement the advances
in software-based devices
Digital Health Innovation Action Plan 2017
• Regulatory exclusion of certain medical software and lifestyle mobile apps under the
revised 21st Century Cures Act
• Development of a precertification program for faster launches for certain products
(including AI based products)
• Growing FDA’s medical software technology expertise through talent hiring
19
Future Trends
Key Trends
5G will enable distributed computing and push
the real-time analytics envelope
FDA will continue to embrace Software as a
Medical Device (SaMD) to approve diagnoses of
an increasingly broader swath of conditions
Combination of AI/ML/DL + high resolution
imaging/capture will continue to democratize
CV, especially in areas like lab diagnostics
Precision medicine is becoming reality: closed
loop from drug discovery to therapy,
adherence/compliance/and impact
Oncology/Radiology/Pathology will become
increasingly automated as AI/DL algorithms
continue to improve
Portable devices as well as smart phones or
smart phone-based peripherals will continue to
“consumerize” healthcare
20
Important Disclosure
21
The Information and opinions in this report have been prepared by Woodside Capital Partners International, LLC, and its affiliate, Woodside Capital
Securities, LLC (collectively, “Woodside”). All information supplied or obtained from this report is for informational purposes only and should not be
considered investment advice or guidance, an offer of or a solicitation of an offer to buy or sell a security, or a recommendation or an endorsement by
Woodside Capital Securities, LLC, Woodside Capital Partners International, LLC and Woodside Capital Partners UK, LLP of any security. Further information
on any of the securities mentioned in this report may be obtained from our offices. Other than disclosures relating to Woodside Capital Securities, LLC the
information herein is based on sources we believe to be reliable but is not guaranteed by us and does not purport to be a complete statement or summary
of the available data. Any opinions expressed herein are statements of our judgment on this date and are subject to change without notice. Periodic
updates may be provided on companies/industries based on company specific developments or announcements, market conditions or any other publicly
available information.
Important Disclosures:
Woodside Capital Securities, LLC is not a market maker in any securities mentioned in this report.
Woodside Capital Securities, LLC and their officers and employees may from time to time acquire, hold, or sell a position in the securities mentioned in this
report. Woodside Capital Securities, LLC compensates individuals for activities and services intended to benefit the firm's investor clients. Compensation
determinations for individuals, including the author(s) of this report, are based on a variety of factors, and may include the overall profitability of the firm
and the revenues derived from all sources, including revenues from investment banking.
Woodside Capital Securities, LLC is a registered broker-dealer and member of FINRA (www.finra.org) and SIPC (www.sipc.org).
Woodside Capital Securities, LLC is an affiliate of Woodside Capital Partners International, LLC and Woodside Capital Partners UK, LLP.
One or more private companies in this report have confidentially retained Woodside Capital Securities, LLC, Woodside Capital Partners International, LLC
or Woodside Capital Partners UK, LLP as an advisor. In addition, in the future Woodside may seek to offer investment banking services to, and collect fees
from, any of the companies featured in this report.
Third Party Disclosures:
Any analyst opinions, ratings, and public company reports included in this report are provided by third-parties unaffiliated with Woodside Capital
Securities, LLC, Woodside Capital Partners International, LLC and Woodside Capital Partners UK, LLP. Woodside Capital Securities, LLC, Woodside Capital
Partners International, LLC and Woodside Capital Partners UK, LLP makes no guarantees that information supplied is accurate, complete, updated or
timely, and does not provide any warranties regarding results obtained from its use.
rudy.burger@woodsidecap.com
Vini.jolly@woodsidecap.com
Thank You!

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"Vision Opportunities in Healthcare," a Presentation from Woodside Capital Partners

  • 1. Vision Opportunities in Healthcare December, 2019 Rudy Burger Vini Jolly
  • 2. 2 Introduction to WCP AutoTech Report ▪ M&A, strategic partnerships, and corporate finance advisory ▪ Focused on emerging growth technology companies ▪ Founded in 2001: over $8 billion in transaction value ▪ Offices in Silicon Valley, London, Shanghai ▪ Dedicated Digital Health and Computer Vision corporate finance practice Digital Health Artificial Intelligence Collaborative Robots
  • 3. Embedded Vision / Visual AI Market Map Camera Modules Sensors Illumination Lenses Cameras Processors Boards and Modules Processors and SoCs SoftwareMemory Enabling Services & Tools Development Tools Image & Video Data Standards Components Subsystems Open SourceDesign & Manufacturing Services Silicon IP Automotive Tier 1 Suppliers Consumer RetailTransportation Industrial Security & Surveillance Defense & Aerospace Communication Media & Entertainment Agriculture Healthcare EnablingTechnologiesSystems&Solutions 3
  • 4. Market Size – US Health Spending United States, 1967 to 2017, Selected Years, and 10-year Projection 4 $52 $174 $517 $1,135 $2,295 $3,492 $5,963 $0 $1,000 $2,000 $3,000 $4,000 $5,000 $6,000 $7,000 1967 1977 1987 1997 2007 2017 2027P Billions Source: CMS.gov
  • 5. 5 Market Size – US Healthcare Spending Per Capita (’00 - ’18) 4.6k 4.9k 5.3k 5.7k 6.1k 6.4k 6.8k 7.2k 7.4k 7.7k 7.9k 8.2k 8.4k 8.6k 9.0k 9.5k 9.9k 10.2k 10.6k $0k $2k $4k $6k $8k $10k $12k 2000 2002 2004 2006 2008 2010 2012 2014 2016 2018 Source: CMS.gov
  • 6. US Healthcare Spending by Type of Product/Service 33% 20%9% 5% 5% 4% 3% 3% 2% 2% 14% Hospital Care Physician and Clinical Services Retail Prescription Drugs Other Health, Residential and Personal Care Services Nursing Care Facilities and Continuing Care Retirement Communities Dental Services Home Health Care Other Professional Services Other Non-Durable Medical Products Durable Medical Equipment OthersTotal Spending: USD3.65 tn 6Source: CMS.gov
  • 7. US Healthcare Spending – Key Facts Total spending on healthcare by Americans in 2018 USD3.65 tn Growth in spending over 2017 4.4% Estimated growth in spending during 2018 - 2027 5.5% Spending per person USD11,212 Spending goes to hospitals, doctors, and clinical services GDP share related to healthcare spending 17.7%59% Of all medical spending goes to waste 25% Number of deaths due to misdiagnosis 40,000 – 80,000 7Source: CMS.gov
  • 8. Benefits of Computer Vision in Healthcare • More accurate diagnoses of medical image data • Reduce redundant surgical procedures and expensive therapies • Detect the slightest presence of a condition Precise Diagnoses • Many fatal illnesses need to be diagnosed in their early stages. CV enables the early detection of symptoms leading to timely treatment and increased probability of survival Timely Detection of Illness • The use of CV in healthcare can lessen the time doctors take in analyzing reports and images – thus giving them more time to spend with patients and provide personalized and constructive advice Improved Patient Care • CV technology enables doctors to remotely monitor and analyze health and fitness metrics to assist patients to make faster and better medical decisions Health Monitoring • CV enables pharmaceutical companies to significantly increase throughput Reduce Drug Development Costs 8
  • 9. 9 Computer Vision in Healthcare Applications Source: Health Tech Magazine • Facial/Feature analytics • Pharma/Clinical Trial adherence • Child/Crib monitoring • Physical Therapy • Pain Management Remote Monitoring, Care & Adherence • AR/VR/Mixed Reality Training across domains • Remote Surgical Applications • Growing application list (Cardio, Lung, Hernia) Remote/Robotic Surgery/Training Drug Discovery • Visualization • High Throughput Molecular/Target simulations • Cellular Level Analysis Medical Imaging/Diagnostics • Radiology (MRI/CT/X- ray) • Pathology (Biopsies) • Oncology • Dermatology • Opthalmology • Cardiology (3D imaging) • Neurology (Strokes, Brain scans) • Lab Diagnostics • Genomics
  • 10. 10 Healthcare Computer Vision Market Map Source: CB Insights, News Releases, Pitchbook Imaging & Diagnostics Drug Discovery Remote/Patient Monitoring Virtual Assistant Clinical Trials Nutrition Compliance Mental Health Genomics Fitness Wearables
  • 11. 3,500 2,625 1,750 875 0 11Source: Tractica $Millions 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 Medical Imaging & Diagnostics Clinical trials Surgeries Other Application Patient management and Research $200M $3,450.3M CAGR 42.8% Global Computer Vision in Healthcare Market by Application
  • 12. $1.0 $1.0 $7.9 $27.3 $22.2 $26.7 $139.4 $217.9 $492.9 1 1 6 7 9 12 12 24 26 2011 2012 2013 2014 2015 2016 2017 2018 2019 Funding ($M) # of Deals Computer Vision in Healthcare Venture Funding Source: Pitchbook 12
  • 13. Bringing AI and Deep Learning to pathology to automate rapid and accurate diagnoses AI for radiology (CT and X-ray) to detect abnormalities and speed time to diagnoses for everything from bone density to cranial bleeding AI and Cloud Supercomputing for fast, accurate image analysis especially for cardiovascular and lung conditions Brings affordable, scalable and accurate blood diagnostics to the point-of-care, thereby accelerating better patient outcomes and improving healthcare for all Visualization & Deep Learning for drug discovery Securely stream patient photographs and wound analysis directly to your desktop Designer of a medical imaging device that reduces the cost of real-time and 3D imaging and treatment Non-invasive coronary artery disease detection using 3D image rendering Machine vision based facial analysis to identify patient adherence Machine vision to analyze movement and falls for patients/seniors Using computer vision for remote health monitoring Cutting Edge Computer Vision Healthcare Companies 13Source: Crunchbase
  • 14. 14 Centralized vs. Remote Data Acquisition Source: Company Websites, Secondary Research Lab Diagnostic Cardiology DNA Testing MRI CT ScanUltrasound Centralized Data Acquisition & Analytics Opthalmology DermatologyCrib Cam Lab Diagnostics Remote Monitoring Bio-monitoring Point of Care/Remote Data Acquisition & Analytics
  • 15. Best Funded Companies in Computer Vision Healthcare Company Name Deal Date Company Stage Overview Recent Funding ($M) Pre-money Valuation ($M) Tempus, United States 5/30/2019 Series F Developer of a health care data analytics platform designed to improve patient outcomes. $200.00 $3,100.00 PathAI, United States 4/17/2019 Series B Developer of an AI-powered research platform intended to improve the accuracy and efficiency of cancer diagnosis and treatment. $60.00 - Healthy.io, Israel 9/11/2019 Series C The company's computer vision and artificial intelligence algorithms based platform captures test strip images using smartphone camera, analyze chemical color of urine test strips and give instant reports. $60.00 - ImagenTechnologies, United States 9/12/2018 Series B Developer of a medical diagnostic technology designed to offer medical imaging services to reduce diagnostic errors and improve patient outcomes. $41.00 $75.00 Paige.ai, United States 11/27/2019 Series B Developer of computational pathology modules intended for rapid diagnostic stratification, cancer detection, tumor segmentation, prediction of treatment response and overall survival. $33.69 $208.69 Arterys, United States 11/3/2017 Series B Developer of a medical imaging analytics platform designed to offer improved patient care. $30.60 $52.00 OrCam, Israel 2/20/2018 Provider of a portable artificial vision device designed to help the visually impaired understand text and identify objects easily. $30.40 $1,000.00 Sight Diagnostics, Israel 2/14/2019 Series B Developer of automated microscopy device designed to improve healthcare for everyone through smarter blood testing. $27.80 - AiCure, United States 11/7/2019 Series C Provider of an intelligent medical assistant services designed to leverage a visual recognition platform to monitor patient progress. $24.50 - Gauss Surgical, United States 10/17/2018 Series C The company leverages computer vision and machine learning to deliver mobile applications for the operating room, with a focus on improving patient safety, quality and outcomes. $20.00 $75.00 15
  • 16. 16 Key Portfolio Companies of Major Investors Source: 3DS, Medical Device Network, Francisco Partners, WellSoft, Point Click Care, Secondary Research Investors Key Portfolio Companies Khosla Ventures HealthTap, Zebra Medical Vision, Curai, Arpeggio Bioscience, Olive (RPA) DCVC Zymergen, Culture Bioscience, CloudMedx, ProteinQure, HumanDx Andreessen Horowitz TwoAR, Freenome Google Ventures Flatiron, Insitro, Verana Health, Owkin, Fathom (Medical Coding Automation), DxOptics, ImagenTechnologies, Recursion Pharmaceuticals, Atomwise General Catalyst Mindstrong Health, OM 1, Curai, Imprivata, Color, Roman Health, Avant-Grade Health, Aidin, Humedica, Prematics General Atlantic Change Healthcare, EviCore Healthcare, Eclipsys, MultiPlan, Envoy, Amedes Group, CitrusTech, Change Healthcare, Alignment Healthcare, Capario, OneOncology, eRx Network, MedUnite, Healthcare Technology Management Services, MeDIStar Group Polaris OM 1, Gauss Surgical, Imprivata, Phytel, Phreesia, Free & Clear, Quartet Health, Partsource, Perpetual Motion, Prospex Medical, Sentillion, Strata Health Solutions, Wellsphare Digitix Savonix, Tissue Analytics, Siris Medical, WellDoc Canaan Abyrx, Ambra, Anliva Biosciences, Arrakis Therapeutics, Arvinas, Corvium, Genome Medical, Glooko, Roman, Truveris, Vineti Bessemer Ventures AccuVein, Artemis Health, Bright Health, Collective Medical, Docent Health, Fractyl, Groups, Kymera Therapeutics, Nym, Qventus, Subtle Medical, TScan Therapeutics
  • 17. Big Tech Transforming Healthcare (1/2) Large data companies like Google, Amazon and Apple are making huge strides into healthcare as technological advancements have enabled digital healthcare to advance rapidly • Most active big tech firm in healthcare AI initiatives • Founded Verily in 2015 • Project Medical Digital Assist focused on AI usage in physician assistance • Developed algorithm to diagnose diabetic retinopathy in images • Acquired fitness activity tracker Fitbit for $2.1 billion • Partnered with biotech firms C4 Therapeutics and AbbVie pharmaceuticals via Calico • Corporate healthcare system – Amazon Care • Purchased online pharmacy startup PillPack • Plans to sell medical records reading software • Working on cancer research and other healthcare related ventures such as last-mile delivery • Focus on patient facing products as well as streamlining medical payments • Received FDA clearance for new heart monitoring Apple Watch feature (EKG) • Implementing Apple Health Records system through hospital partnerships • Acquired sleep monitor company Beddit (May 2017) and personal health data platform Gliimpse (2016) 17
  • 18. Big Tech Transforming Healthcare (2/2) The healthcare industry presents tremendous business opportunity, encouraging other top tech companies to adopt healthcare innovation • Launched health care division in 2017 that focuses on AI for patient care improvement • Alliance with Walgreens to develop new health care innovations • Offering healthcare focused solutions through Azure suite • Collaborative research on applying AI to MRI scans • Acquires neural interface startup CTRL-Labs for its mind- reading wristband • Plans to launch “Preventive Health” tool to prompt users to get regular checkups • Acquired predictive healthcare technology business of BioSensics • Bought seniors-focused health services company Critical Signal Technologies and GreatCall, emergency concierge & monitoring services provider • Acquired Auris Health’s robotic platform technology used in diagnostic and lung therapeutic procedures • Partnered with accelerator Founders Factory with focus on startups in the consumer healthcare space • Intel Capital invested in Lumiata, which improves quality of hospital care through data and predictive analytics • Invested in EchoPixel, which is developing tools to enable non-invasive colon cancer screening • Launched Uber Health: non- medical-emergency transportation service 18
  • 19. FDA Gears for Innovation in Medical Technology As shift towards new technologies gains momentum, the FDA has worked to modernize their regulatory approach to facilitate innovation to improve the healthcare system: Proposed regulatory framework for dynamic AI systems to ensure realization of the full potential of the technology Approval of 106 novel devices in 2018, including artificial intelligence based technologies for diabetic retinopathy diagnosis Creation of a Center for Excellence for Digital Health to complement the advances in software-based devices Digital Health Innovation Action Plan 2017 • Regulatory exclusion of certain medical software and lifestyle mobile apps under the revised 21st Century Cures Act • Development of a precertification program for faster launches for certain products (including AI based products) • Growing FDA’s medical software technology expertise through talent hiring 19
  • 20. Future Trends Key Trends 5G will enable distributed computing and push the real-time analytics envelope FDA will continue to embrace Software as a Medical Device (SaMD) to approve diagnoses of an increasingly broader swath of conditions Combination of AI/ML/DL + high resolution imaging/capture will continue to democratize CV, especially in areas like lab diagnostics Precision medicine is becoming reality: closed loop from drug discovery to therapy, adherence/compliance/and impact Oncology/Radiology/Pathology will become increasingly automated as AI/DL algorithms continue to improve Portable devices as well as smart phones or smart phone-based peripherals will continue to “consumerize” healthcare 20
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