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IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308
_______________________________________________________________________________________
Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 218
BRAIN TUMOR CLASSIFICATION USING ARTIFICIAL NEURAL
NETWORK ON MRI IMAGES
Shubhangi S. Veer (Handore)1
, Pradeep M. Patil2
1
Research Scholar, Ph.D student,JJTU , Rajasthan
handore.shubhangi@gmail.com
2
Jt. Director, Trinity College of Engg. and Research ,Pune ,Maharashtra.
patil.pm@rediffmail.com
Abstract
In this paper, an attempt has been made to summarize the multi-resolution transformation and the different classifiers useful to
analyze the brain tumor using MRI. X-ray, MRI, Ultrasound etc. are different techniques used to scan brain tumor images.
Radiologist prefers MRI to get detail information about tumor to help him diagnoses. In this paper we have used MRI of brain
tumor for analysis. We have used Digital image processing tool for detection of the tumor. The identification, detection and
classification of brain tumor have been done by extracting features from MRI with the help of wavelet transformation. The MRI of
brain tumor is classified into two categories normal and abnormal brain. In this work Digital image processing has been used as
a tool for getting clear and exact details about tumor in earlier stages. This helps the physicians and practitioners for diagnoses.
Key word – Brain tumor, Wavelet transform, segmentation.
--------------------------------------------------------------------***----------------------------------------------------------------------
1. INTRODUCTION
Brain tumor is the main cause of cancer deaths worldwide.
Brain tumor can affect people at any age. Brain tumor
increases mortality among children and adults. The brain is
one of the complex organs in the human body. There are
more than 100 billion nerves present in human brain that are
in an overlapped form. Due to such a complex structure of
the human brain, a diagnosis of the tumor area in the brain is
a challenging task. The tumor is due to uncontrollable
growth of cells in the brain. There are basically two types of
primary brain tumors that are Benign tumor and Malignant
tumor.
The tumor is small in size. The identification of the tumor is
based on their growth pattern. Benign tumor grows slowly
and it has well defined borders. It can be removed
completely by surgery and it does not spread in the spinal
cord, other parts of brain or other areas of the body. The
malignant type of tumor is fast-growing and affects the
healthy brain cells and may spread to other parts of the brain
or spinal cord. It is more harmful and may remain untreated.
So detection of such brain tumor location, identification and
classification in earlier stage is a serious issue in medical
science [1].
Imaging technology in Medicine helps doctors to observe
the interior portions of the human body for easy diagnosis.
Digital image processing is one of the tool by which it is
easier to analyze medical images in a short span of times, by
digital image processing it is possible to detect, identify and
analyze the brain tumor easily. Digital image processing
also has an advantage like reproducing original data without
any change and enhancing an image which helps the
Radiologist for diagnosis in earlier stage.
2. LITERATURE REVIEW
According to National Brain Tumor Society, people having
primary tumor are about 688,000 and according to Central
Nervous System (CNS) in the United States, 138,000 people
with malignant tumor and 550,000 with nonmalignant
tumors [2]. So classification of tumor is an important issue.
Numbers of authors have worked on this issue, which
described in this session. ShanShen et al proposed fuzzy c-
means clustering (IFCM). The proposed algorithm is based
on neighborhood attraction. It is considered that it exist
between neighboring pixels. This neighborhood attraction
depends on the pixel intensities , the spatial position of the
neighbor pixels and on neighborhood pixel structure . The
classification of tumor is done with the help of artificial
neural network (ANN) based on the similarity between
feature vectors [3]. Dina Aboul Dahab et al proposed a
technique for the enhancement an image in a spatial domain
based on direct manipulation of pixels in a neighborhood of
pixels. The enhancement in frequency domain based on the
concept of the convolution theorem and spatial filters. In
this paper author used probabilistic neural networks (PNN)
which is based on learning vector quantization (LVQ). LVQ
is a supervised competitive learning technique; it defines
object boundaries and the rules for pixels that are the nearest
neighborhood [4]. Chandrakant Biradar et al proposed an
algorithm to extract the tumor region from MRI images.
They applied DWT to decompose an image. The author
applied segmentation on DWT image to extract tumor
region. They extracted the features like size; shape and
texture to classify the type of tumor .they have used SVM
classifier for classification [5]. Atiq Islam et al proposed an
algorithm for segmentation of brain tumor MRI. Due to
complex appearance of brain in MRI, author designed
IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308
_______________________________________________________________________________________
Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 219
multiresolutionfractal technique to get multifractal features
form tumor segmented images. The segmentation of
proposed multiracial feature compared with Gabor features
in this paper. The classification has been done by using
multiracial features of tumor with the help of novel
DiverseAdaBoost SVM classifier to improve tumor
classification rate [6]. Meiyan Huang et al proposed the
classification framework with the help of local independent
projection into the classical classification model. The
performance evaluation of proposed LIPC classifier had
done by using two-spiral structure by authors. They also
compared two classification techniques like SRC and
Support Vector Machine (SVM) [7]. Dr. P.V. Ramaraju et al
proposed an algorithm for classification of brain tumor.
They have used MRI of brain to detect and classify a tumor.
This algorithm is based on a wavelet transformation. The
wavelet transformation is used to extract features from brain
tumor MRI. Author has used feed forward probabilistic
neural networks (PNN) to classify brain tumor based on
these extracted features. They classified MRI of brain into
benign, malignant or normal classes [8].
3. PROPOSED METHODOLOGY
The MRI of brain is represented here as a gray scale image.
These gray scale images are having intensity levels ranging
from 0-255, where 0 represents black color and 255
represents white color. Figure 1 shows a sample MRI of
brain tumor from the data base used for this work. The
database is of 72 brain MRI image.
Figure.1.Brain Tumor MRI image
The blood cells in brain are represented by white color and
remaining portion of brain is represented by different gray
color shade, whose intensity is less than 255 in MRI. Using
this basic idea we have designed our algorithm to find out
first order textural features from MRI of brain tumor and
selection of exact classifier technique from the study of
different classifiers based on the features.
In this proposed algorithm MRI image of brain as are used
as an input. These MRI images of brain are clearer than CT
scan images. Figure 2 shows various stages that are
followed for tumor declaration. The major blocks used are
I. Preprocessing.
II. Feature extraction
III. Classification
I. PREPROCESSING
Input for proposed algorithm is a brain tumor image
obtained from MRI. These images are not that much clear
for tumor declaration. So preprocessing is the first step to
make an input image more visible to human eye. At this
stage to remove the blurriness of MRI images we have used
median filter .Median filter remove the noise from MRI of
brain tumor. Median filter gives a smooth image. After
getting a smooth image, the next step is enhancement. The
image enhancement increases sharpness of this filtered
image. Here the enhancement of this filtered image has
been done using power law transform. Power log transform
gives sharper image then the input image.
II. FEAURETURE EXTRAXTION
Feature extraction is a stage where we have extracted the
features from the sharpened image, which required as an
input for classifier. In this algorithm we have used discrete
cosine transformation (DWT). It is one of the types of
wavelet transformation.
In this algorithm, two level decomposition of „Symlet‟ DWT
is used. This transform is applied to enhanced image. The
DWT divides enhanced image into four regions using low
pass filter and high pass filter bank and gives four different
coefficients like absolute coefficient, diagonal coefficient,
horizontal coefficient and vertical coefficient. The major
information of an image is present in absolute coefficients as
compare to remaining three regions. So we have selected
absolute coefficients for feature extraction. We extracted
different features like Contrast, Homogeneity, Correlation,
Energy etc. These features are used as an input to classifier
for tumor declaration.
Figure.2. Block diagram of tumor declaration
Tumor
Declaration
Image
Acquisition
Preprocessing Feature Extraction Classification
IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308
_______________________________________________________________________________________
Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 220
III. CLASSIFICATION
Classification is the essential step, where the brain tumor
MRI classified into cancerous and noncancerous classes.
The selection of a particular classifier is based on number of
inputs and number of outputs to the classifier, features
extracted from patterns as well as the type of input images.
There are number of classifiers can be used to classify an
images into different classes. Some classifiers are as
follows.
a. MULTILAYER PERCEPTRONS (MLP)
Multilayer perceptron‟s are layered feed forward networks.
These networks are mostly used for classification of an
image into different classes. Multilayer perceptron‟s are
useful in number of applications, where statistical
classification is required.
b. PRINCIPAL COMPONENT ANALYSIS
(PCA)
PCA is useful to approximate the original information with
the help of least number of component .PCA is useful for
approximating data with lower dimensional vectors. The
PCA approach is based on eigenvectors, which is based on
covariance matrix of an original image. By using PCA the
test image was first identified by projecting the original
image onto the eigen space to extract the corresponding set
of weights and then the comparison has done with the help
of a set of weights of an image in the training set [9].
c. SUPPORT VECTOR MACHINE (SVM)
After feature extraction from an image, classification is the
main task. The performance of classifier depends upon the
number of features, samples. There are number of classifiers
available for classification. SVM is one of the supervised
classifier which gives good results in medical diagnosis. It
gives better result in a high dimension feature space. SVM
has also been applied on different real world problems such
as face recognition, text categorization; cancer diagnosis
.This SVM classifier gives better result for classification of
binary MRI images [10].
d. PROBABLISTIC NEURAL NETWORK (PNN)
Probabilistic Neural Network is the classifier that is useful
for medical application. In some algorithms feature
extraction has done with the help of GLCM and
classification of images has done by using PNN. This
classifier gives fast and accurate classification [11].
In proposed methodology MLP classifier has used its
advantage is that it is easy to use and it can easily
approximate any gray scale input or output map. The
MATLAB and Nerosolution tools have been used for the
classification of brain tumor MRI.
4. RESULT AND DISCUSSION
In proposed algorithm classification of brain tumor has done
using MLP. MLP verified these MRI input and classified it
into Benign or Malignant tumor classes. Here MLP
designed with number of hidden and output layers with
different transfer functions and learning rules along with
various percentages of training and testing data. Some
sample results shown here are of three and five hidden
layers and with different hidden layer transfer functions like
TanhAxon, SigmoidAxon and LinearsigmoidAxon. The
output layer transfer function is Sigmoid Axon. The learning
rule at hidden layers and output layer is Levenbergmarqua.
There are 29 different MLP combinations with their results
shown here. This includes graph of mean square error
(MSE) after three runs. The table which gives information
regarding the minimum MSE, regression factor and
percentage accuracy. By referring these results it‟s easy to
verify a MLP network which gives accurate result by
considering the conditions like true positive, false positive,
true negative and false negative.
1. The results of MLP that designed with 50% database for
training and 50%database for testing a network with three
hidden layers has been shown in Figure 3 and Table 1. The
TanhAxon function at hidden layer, Sigmoid Axon
function at output layer and Levenberg learning rule has
been used to design this MLP classifier.
Figure.3. Average MSE with S.D.B. for three runs
Table.1. Performance of MLP
Best
Networks Training
Cross
Validation
Run # 1 2
Epoch # 999 999
Minimum MSE 0.006136364 1.77468E-09
Final MSE 0.006136364 1.79021E-09
Output / Desired Col1(1) Col1(0)
Col1(1) 13 6
Col1(0) 5 14
-0.1
0
0.1
0.2
0.3
1
100
199
298
397
496
595
694
793
892
991
AverageMSE
Epoch
Average MSE with Standard
Deviation Boundaries for 3 Runs
Training
+ 1 Standard
Deviation
- 1 Standard
Deviation
Cross
Validation
IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308
_______________________________________________________________________________________
Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 221
Performance Col1(1) Col1(0)
MSE 0.290002106 0.289712851
NMSE 1.163230668 1.162070435
MAE 0.290280969 0.289828325
Min Abs Error 2.99852E-08 8.58814E-08
Max Abs Error 1.009131705 1.004234283
r 0.420533115 0.421132249
Percent Correct 72.22222222 70
2. The results of MLP that designed with 50% database for
training and 50%database for testing a network with three
hidden layers has been shown in Figure 4 and Table 2. The
Sigmoid Axon function at hidden layer, Sigmoid Axon
function at output layer and Levenberg learning rule has
been used to design this MLP classifier.
Figure.4. Average MSE with S.D.B. for three runs
Table.2. Performance of MLP
Best
Networks Training
Cross
Validation
Run # 1 1
Epoch # 1000 1000
Minimum MSE 0.006136364 6.87844E-07
Final MSE 0.006136364 6.87844E-07
Output / Desired Col1(1) Col1(0)
Col1(1) 12 5
Col1(0) 6 15
Performance Col1(1) Col1(0)
MSE 0.284861912 0.284861912
NMSE 1.14261278 1.14261278
MAE 0.291762638 0.291762638
Min Abs Error 1.35502E-07 1.35502E-07
Max Abs Error 1.000821603 1.000821603
r 0.419999862 0.419999862
Percent
Correct 66.66666667 75
3. The results of MLP that designed with 60% database for
training and 40%database for testing a network with three
hidden layers has been shown in Figure 5 and Table 3. The
TanhAxon function at hidden layer, Sigmoid Axon
function at output layer and Levenberg learning rule has
been used to design MLP classifier.
Figure.5. Average MSE with S.D.B. for three runs
Table.3. Performance of MLP
Best
Networks Training
Cross
Validation
Run # 1 1
Epoch # 727 6
Minimum MSE 0.009878049 0.000508521
Final MSE 0.009878049 0.101250136
Output / Desired Col1(0) Col1(1)
Col1(0) 10 1
Col1(1) 5 14
Performance Col1(0) Col1(1)
MSE 0.171753813 0.176993994
NMSE 0.68701525 0.707975976
MAE 0.208805816 0.204471573
Min Abs Error 0.01867669 0.003248765
Max Abs Error 0.98049437 0.996037063
r 0.657378803 0.655903134
Percent
Correct 66.66666667 93.33333333
4. The results of MLP that designed with 70% database for
training and 30%database for testing a network with three
hidden layers has been shown in Figure 6 and Table 4.The
TanhAxon function at hidden layer, Sigmoid Axon function at
output layer and Levenberg learning rule has been used to
design this MLP classifier.
-0.1
0
0.1
0.2
0.3
0.4
1
100
199
298
397
496
595
694
793
892
991
AverageMSE
Epoch
Average MSE with Standard
Deviation Boundaries for 3 Runs
Training
+ 1 Standard
Deviation
- 1 Standard
Deviation
Cross
Validation
-0.1
0
0.1
0.2
0.3
0.4
0.5
1
100
199
298
397
496
595
694
793
892
991
AverageMSE
Epoch
Average MSE with Standard
Deviation Boundaries for 3 Runs
Training
+ 1 Standard
Deviation
- 1 Standard
Deviation
Cross
Validation
IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308
_______________________________________________________________________________________
Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 222
Figure.6. Average MSE with S.D.B.for three runs
Table.4. Performance of MLP
Best
Networks Training
Cross
Validation
Run # 1 1
Epoch # 1000 50
Minimum MSE 0.020663265 0.000487995
Final MSE 0.020663265 0.101249976
Output / Desired Col1(0) Col1(1)
Col1(0) 8 1
Col1(1) 3 10
Performance Col1(0) Col1(1)
MSE 0.159034196 0.16115271
NMSE 0.636136782 0.644610842
MAE 0.178435182 0.179954692
Min Abs Error 0.000593434 3.47955E-05
Max Abs Error 0.997620132 1.000161918
r 0.678696463 0.673600142
Percent
Correct 72.72727273 90.90909091
5. The results of MLP that designed with 80% database for
training and 20% database for testing a network with three
hidden layers has been shown in Figure 7 and Table 5.The
Linear SigmoidAxon function at hidden layer, Sigmoid
Axon function at output layer and Levenberg learning rule
has been used to design this MLP classifier.
Figure.7. Average MSE with S.D.B.for three runs
Table.5. Performance of MLP
Best
Networks Training
Cross
Validation
Run # 1 3
Epoch # 141 4
Minimum MSE 0.038974871 5.52201E-05
Final MSE 0.038974871 0.074255015
Output / Desired Col1(1) Col1(0)
Col1(1) 0 0
Col1(0) 9 6
Performance Col1(1) Col1(0)
MSE 0.585828947 0.586106719
NMSE 2.440953948 2.442111331
MAE 0.597553803 0.597578527
Min Abs Error 0.011661897 0.011327293
Max Abs Error 0.988214604 0.98850352
r 0.681737659 0.681731578
Percent Correct 0 100
6. The results of MLP that designed with 50% database for
training and 50%database for testing a network with five
hidden layers. The TanhAxon function at hidden layer has
been shown in Figure 8 and Table 6, Sigmoid Axon function
at output layer and Levenberg learning rule has been used to
design this MLP classifier.
Figure.8. Average MSE with S.D.B. for three runs
Table.6. Performance of MLP
Best
N Networks Training
Cross
Validation
Run # 1 2
Epoch # 1000 10
Minimum MSE 0.018409091 0.004710426
Final MSE 0.018409091 0.101250078
Output / Desired Col1(1) Col1(0)
Col1(1) 10 0
Col1(0) 5 23
0
0.05
0.1
0.15
0.2
0.25
1
100
199
298
397
496
595
694
793
892
991
AverageMSE
Epoch
Average MSE with Standard
Deviation Boundaries for 3 Runs
Training
+ 1 Standard
Deviation
- 1 Standard
Deviation
Cross
Validation
-0.2
-0.1
0
0.1
0.2
0.3
0.4
0.5
1
100
199
298
397
496
595
694
793
892
991
AverageMSE
Epoch
Average MSE with Standard
Deviation Boundaries for 3 Runs
Training
+ 1 Standard
Deviation
- 1 Standard
Deviation
Cross
Validation
-0.05
0
0.05
0.1
0.15
0.2
0.25
1
100
199
298
397
496
595
694
793
892
991
AverageMSE
Epoch
Average MSE with Standard
Deviation Boundaries for 3 Runs
Training
+ 1 Standard
Deviation
- 1 Standard
Deviation
Cross
Validation
IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308
_______________________________________________________________________________________
Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 223
Performance Col1(1) Col1(0)
MSE 0.128431286 0.127960088
NMSE 0.537550078 0.535577877
MAE 0.209681988 0.206906826
Min Abs Error 0.02899802 0.026975136
Max Abs Error 0.934267124 0.936158062
r 0.721359045 0.722186609
Percent
Correct 66.66666667 100
7. The results of MLP that designed with 60% database for
training and 40%database for testing a network with five
hidden layers has been shown in Figure 9 and Table 7. The
SigmoidAxon function at hidden layer, Sigmoid Axon
function at output layer and Levenberg learning rule has
been used to design this MLP classifier.
Figure.9. Average MSE with S.D.B. for three runs
Table.7. Performance of MLP
Best
Networks Training
Cross
Validation
Run # 1 1
Epoch # 999 1000
Minimum MSE 0.004939024 3.08311E-13
Final MSE 0.004939024 3.08311E-13
Output / Desired Col1(0) Col1(1)
Col1(0) 15 6
Col1(1) 4 5
Performance Col1(0) Col1(1)
MSE 0.333292125 0.333295741
NMSE 1.435229248 1.43524482
MAE 0.333314401 0.333316308
Min Abs Error 8.81615E-08 4.62701E-08
Max Abs Error 1.00002567 1.000022725
r 0.256671268 0.256665338
Percent
Correct 78.94736842 45.45454545
8.The results of MLP designed with 70% database for
training and 30% database for testing a network with five
hidden layers has been shown in Figure10 and Table 8. The
TanhAxon function at hidden layer, Sigmoid Axon function
at output layer and Levenberg learning rule has been used to
design this MLP classifier.
Output / Desired Col1(1) Col1(0)
Col1(1) 5 3
Col1(0) 3 11
Performance Col1(1) Col1(0)
MSE 0.272784227 0.272809807
NMSE 1.178817554 1.178928093
MAE 0.272883818 0.272919695
Min Abs Error 2.91852E-06 1.71976E-06
Max Abs Error 1.000219309 1.000321875
r 0.410450333 0.410364346
Percent Correct 62.5 78.57142857
Figure.10. Average MSE with S.D.B. for three runs
Table.8. Performance of MLP
Best
Networks Training
Cross
Validation
Run # 1 2
Epoch # 1000 347
Minimum MSE 0.012397959 1.01311E-09
Final MSE 0.012397959 1.08339E-06
9. The results of MLP that designed with 70% database for
training and 30%database for testing a network with five
hidden layers has been shown in Figure 11 and Table 9. The
Sigmoid Axon function at hidden layer, Sigmoid Axon
function at output layer and Levenberg learning rule has
been used to design this MLP classifier.
Figure.11. Average MSE with S.D.B. for three runs
-0.2
0
0.2
0.4
0.6
1
100
199
298
397
496
595
694
793
892
991
AverageMSE
Epoch
Average MSE with Standard
Deviation Boundaries for 3 Runs
Training
+ 1 Standard
Deviation
- 1 Standard
Deviation
Cross
Validation
-0.1
0
0.1
0.2
0.3
0.4
1
100
199
298
397
496
595
694
793
892
991
AverageMSE
Epoch
Average MSE with Standard
Deviation Boundaries for 3 Runs
Training
+ 1 Standard
Deviation
- 1 Standard
Deviation
Cross
Validation
-0.1
0
0.1
0.2
0.3
0.4
1
100
199
298
397
496
595
694
793
892
991
AverageMSE
Epoch
Average MSE with Standard
Deviation Boundaries for 3 Runs
Training
+ 1 Standard
Deviation
- 1 Standard
Deviation
Cross
Validation
IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308
_______________________________________________________________________________________
Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 224
Table.9. Performance of MLP
Best
Networks Training
Cross
Validation
Run # 2 2
Epoch # 1000 1000
Minimum MSE 0.012397959 4.63139E-06
Final MSE 0.012397959 4.63139E-06
Output / Desired Col1(1) Col1(0)
Col1(1) 9 3
Col1(0) 1 9
Performance Col1(1) Col1(0)
MSE 0.187784297 0.187778004
NMSE 0.757396663 0.757371284
MAE 0.202055781 0.202035265
Min Abs Error 1.08352E-06 7.20899E-07
Max Abs Error 1.000000176 0.999999931
r 0.631840611 0.631864851
Percent
Correct 90 75
10. The results of MLP that designed with 70% database for
training and 30%database for testing a network with five
hidden layers has been shown in Figure 12 and Table 10.
The Linear Sigmoid Axon function at hidden layer, Sigmoid
Axon function at output layer and Levenberg learning rule
has been used to design this MLP classifier.
Figure.12. Average MSE with S.D.B. for three runs
Table.10. Performance of MLP
Best
Networks Training
Cross
Validation
Run # 3 3
Epoch # 47 37
Minimum MSE 0.02637897 0.00013607
Final MSE 0.02637897 0.006843285
Output / Desired Col1(1) Col1(0)
Col1(1) 9 4
Col1(0) 1 8
Performance Col1(1) Col1(0)
MSE 0.120585703 0.12047363
NMSE 0.486362335 0.485910307
MAE 0.204653233 0.2023745
Min Abs Error 0.008063106 0.002503527
Max Abs Error 1.021844722 1.018708783
r 0.728278251 0.728898772
Percent Correct 90 66.66666667
11. The results of MLP that designed with 80% database for
training and 20%database for testing a network with five
hidden layers has been shown in Figure13 and Table 11. The
Sigmoid Axon function at hidden layer, Linear Sigmoid
Axon function at output layer and Levenberg learning rule
has been used to design this MLP classifier.
Figure.13. Average MSE with S.D.B. for three runs
Table.11. Performance of MLP
Best
Networks Training
Cross
Validation
Run # 3 1
Epoch # 53 30
Minimum MSE 0.028464595 0.005342038
Final MSE 0.028464595 0.005342053
Output / Desired Col1(1) Col1(0)
Col1(1) 6 4
Col1(0) 2 3
Performance Col1(1) Col1(0)
MSE 0.318735299 0.31873529
NMSE 1.280632897 1.280632863
MAE 0.4240641 0.424064103
Min Abs Error 0.088236967 0.088237001
Max Abs Error 0.911763033 0.911762999
r 0.188982237 0.188982237
Percent Correct 75 42.85714286
-0.05
0
0.05
0.1
0.15
0.2
0.25
0.3
1
100
199
298
397
496
595
694
793
892
991
AverageMSE
Epoch
Average MSE with Standard
Deviation Boundaries for 3 Runs
Training
+ 1 Standard
Deviation
- 1 Standard
Deviation
Cross
Validation
0
0.1
0.2
0.3
0.4
0.5
1
100
199
298
397
496
595
694
793
892
991
AverageMSE
Epoch
Average MSE with Standard
Deviation Boundaries for 3 Runs
Training
+ 1 Standard
Deviation
- 1 Standard
Deviation
Cross
Validation
IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308
_______________________________________________________________________________________
Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 225
12. The results of MLP that designed with 90% database for
training and 10%database for testing a network with five
hidden layers has been shown in Figure 14 and Table 12.
The Sigmoid Axon function at hidden layer, TanhAxon
function at output layer and Levenberg learning rule has
been used to design this MLP classifier.
Figure.14. Average MSE with S.D.B. for three runs
Table.12. Performance of MLP
Best
Networks Training
Cross
Validation
Run # 2 2
Epoch # 1000 14
Minimum MSE 0.016071429 0.001209166
Final MSE 0.01607143 0.20251269
Output / Desired Col1(1) Col1(0)
Col1(1) 5 1
Col1(0) 0 2
Performance Col1(1) Col1(0)
MSE 0.141924775 0.142004327
NMSE 0.605545707 0.605885129
MAE 0.180090077 0.180807332
Min Abs Error 0.051770794 0.054609445
Max Abs Error 1.055553126 1.0555548
r 0.745347813 0.745351192
Percent Correct 100 66.66666667
13. The results of MLP that designed with 90% database for
training and 10%database for testing a network with five
hidden layers has been shown in Figure 15 and Table13. The
Sigmoid Axon function at hidden layer, Sigmoid Axon
function at output layer and Levenberg learning rule has
been used to design this MLP classifier.
Figure.15. Average MSE with S.D.B. for three runs
Table.13. Performance of MLP
Best Networks Training Cross Validation
Run # 1 1
Epoch # 823 2
Minimum MSE 0.016071429 0.00125
Final MSE 0.016071429 0.101250941
Output / Desired Col1(1) Col1(0)
Col1(1) 4 0
Col1(0) 0 4
Performance Col1(1) Col1(0)
MSE 0.003086419 0.00308642
NMSE 0.012345676 0.012345679
MAE 0.05555555 0.055555555
Min Abs Error 0.055555544 0.055555555
Max Abs Error 0.055555556 0.055555555
r 1 1
Percent Correct 100 100
7. CONCLUSION
The proposed algorithm for classification of brain tumor
MRI image classified MRI images database effectively into
benign tumor and malignant tumor with the help of MLP
classifier. The MLP classifier used here with three and five
number of hidden layers by using different hidden layer
functions and output layer functions. By observing the
above results, it‟s seen that MLP classifier is the best
classifier for brain tumor MRI database. MLP classifier
classified the database accurately at 90% database for
training and 10%database for testing a network with five
hidden layers, Sigmoid Axon function at hidden layer,
Sigmoid Axon function at output layer with Levenberg
learning rule.
REFERNCES
[1]Manoj K Kowar and Sourabh Yadav, 2012, “Brain
Tumor Detction and Segmentation Using Histogram
Thresholding” , International Journal of Engineering and
-0.1
0
0.1
0.2
0.3
0.4
1
100
199
298
397
496
595
694
793
892
991
AverageMSE
Epoch
Average MSE with Standard
Deviation Boundaries for 3 Runs
Training
+ 1 Standard
Deviation
- 1 Standard
Deviation
Cross
Validation
-0.1
0
0.1
0.2
0.3
0.4
1
100
199
298
397
496
595
694
793
892
991
AverageMSE
Epoch
Average MSE with Standard
Deviation Boundaries for 3 Runs
Training
+ 1 Standard
Deviation
- 1 Standard
Deviation
Cross
Validation
IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308
_______________________________________________________________________________________
Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 226
Advanced Technology (IJEAT) ISSN: 2249 – 8958,
Volume-1, Issue-4, pp. 16-20 .
[2] T. Logeswari and M. Karnan, 2010, “An improved
implementation of brain tumor detection using segmentation
based on soft computing”, Second International Conference
on Communication Software and Networks, ICCSN10, pp.
147-151.
[3] Shan Shen, William Sandham , 2005 , “ MRI Fuzzy
Segmentation of Brain Tissue Using Neighborhood
Attraction With Neural-Network Optimization ”, IEEE
transactions on information technology in biomedicine
Volume 9,issue no.3,pp. 459 -467.
[4] Dina Aboul Dahab, Samy S. A. Ghoniemy, Gamal M.
Selim, 2012, “Automated Brain Tumor Detection and
Identification Using Image Processing and Probabilistic
Neural Network Techniques”, International Journal of
Image Processing and Visual communication, ISSN 2319-
1724 : Volume - 1 , Issue no.2 .
[5]Chandrakant Biradar, Shantkumari, 2013, “Measurement
based Human Brain Tumor Recognition by Adapting
Support Vector Machine”, IOSR Journal of Engineering
(IOSRJEN) e-ISSN: 2250-3021, pp. 2278-8719 Volume 3,
Issue no.9, pp 26-31.
[6] Atiq Islam, Syed M. S. Reza, and Khan M. , 2013
,“Multifractal Texture Estimation for Detection and
Segmentation of Brain Tumors ” , IEEE transactions on
biomedical engineering Volume 60, no.11, pp.3204-3215 .
[7]Meiyan Huang,Wei Yang, YaoWu, Jun Jiang,Wufan
Chen ,2014, “Brain Tumor Segmentation Based on Local
Independent Projection-Based Classification”, IEEE
transactions on biomedical engineering , Volume 61,Issue
no. 10, pp . 2633 -2645.
[8]Dr.P.V.Ramaraju,Shaik Baji, 2014, “Brain Tumour
classification, Detection and Segmentation Using Digital
Image Processing and Probabilistic Neural Network
Techniques”, International Journal of Emerging Trends in
Electrical and Electronics (IJETEE – ISSN: 2320-9569)
Volume 10, Issue no.10,pp. 15-20..
[9] Girja Sahu, Lalit Kumar, P. Bhaiya , 2014, “ A
Survey Paper Based on the Classification of MRI Brain
Images Using Soft Computing Techniques”, International
Journal of Emerging Technology and Advanced
Engineering Website: www.ijetae.com (ISSN 2250-2459,
ISO 9001:2008 Certified Journal,) Volume 4, Issue no.12,
pp.309-314.
[10] Qurat-Ul-Ain , Ghazanfar Latif , Sidra Batool Kazmi ,
2014, “ Classification and Segmentation of Brain Tumor
using Texture Analysis ”, Recent Advances in Artificial
Intelligence , Knowledge Engineering and Databases
ISSN: 1790-5109 ISBN: 978-960-474-154-0, pp.147-155 .
[11] Dr. P.V. Ramaraju and Shaik Baji , 2014, “Brain
Tumour classification, Detection and
Segmentation Using Digital Image Processing
and Probabilistic Neural Network Techniques” ,
International Journal of Emerging Trends in Electrical and
Electronics (IJETEE – ISSN: 2320-9569) Volume 10, Issue
no. 10, pp.15-20.

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Brain tumor classification using artificial neural network on mri images

  • 1. IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308 _______________________________________________________________________________________ Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 218 BRAIN TUMOR CLASSIFICATION USING ARTIFICIAL NEURAL NETWORK ON MRI IMAGES Shubhangi S. Veer (Handore)1 , Pradeep M. Patil2 1 Research Scholar, Ph.D student,JJTU , Rajasthan handore.shubhangi@gmail.com 2 Jt. Director, Trinity College of Engg. and Research ,Pune ,Maharashtra. patil.pm@rediffmail.com Abstract In this paper, an attempt has been made to summarize the multi-resolution transformation and the different classifiers useful to analyze the brain tumor using MRI. X-ray, MRI, Ultrasound etc. are different techniques used to scan brain tumor images. Radiologist prefers MRI to get detail information about tumor to help him diagnoses. In this paper we have used MRI of brain tumor for analysis. We have used Digital image processing tool for detection of the tumor. The identification, detection and classification of brain tumor have been done by extracting features from MRI with the help of wavelet transformation. The MRI of brain tumor is classified into two categories normal and abnormal brain. In this work Digital image processing has been used as a tool for getting clear and exact details about tumor in earlier stages. This helps the physicians and practitioners for diagnoses. Key word – Brain tumor, Wavelet transform, segmentation. --------------------------------------------------------------------***---------------------------------------------------------------------- 1. INTRODUCTION Brain tumor is the main cause of cancer deaths worldwide. Brain tumor can affect people at any age. Brain tumor increases mortality among children and adults. The brain is one of the complex organs in the human body. There are more than 100 billion nerves present in human brain that are in an overlapped form. Due to such a complex structure of the human brain, a diagnosis of the tumor area in the brain is a challenging task. The tumor is due to uncontrollable growth of cells in the brain. There are basically two types of primary brain tumors that are Benign tumor and Malignant tumor. The tumor is small in size. The identification of the tumor is based on their growth pattern. Benign tumor grows slowly and it has well defined borders. It can be removed completely by surgery and it does not spread in the spinal cord, other parts of brain or other areas of the body. The malignant type of tumor is fast-growing and affects the healthy brain cells and may spread to other parts of the brain or spinal cord. It is more harmful and may remain untreated. So detection of such brain tumor location, identification and classification in earlier stage is a serious issue in medical science [1]. Imaging technology in Medicine helps doctors to observe the interior portions of the human body for easy diagnosis. Digital image processing is one of the tool by which it is easier to analyze medical images in a short span of times, by digital image processing it is possible to detect, identify and analyze the brain tumor easily. Digital image processing also has an advantage like reproducing original data without any change and enhancing an image which helps the Radiologist for diagnosis in earlier stage. 2. LITERATURE REVIEW According to National Brain Tumor Society, people having primary tumor are about 688,000 and according to Central Nervous System (CNS) in the United States, 138,000 people with malignant tumor and 550,000 with nonmalignant tumors [2]. So classification of tumor is an important issue. Numbers of authors have worked on this issue, which described in this session. ShanShen et al proposed fuzzy c- means clustering (IFCM). The proposed algorithm is based on neighborhood attraction. It is considered that it exist between neighboring pixels. This neighborhood attraction depends on the pixel intensities , the spatial position of the neighbor pixels and on neighborhood pixel structure . The classification of tumor is done with the help of artificial neural network (ANN) based on the similarity between feature vectors [3]. Dina Aboul Dahab et al proposed a technique for the enhancement an image in a spatial domain based on direct manipulation of pixels in a neighborhood of pixels. The enhancement in frequency domain based on the concept of the convolution theorem and spatial filters. In this paper author used probabilistic neural networks (PNN) which is based on learning vector quantization (LVQ). LVQ is a supervised competitive learning technique; it defines object boundaries and the rules for pixels that are the nearest neighborhood [4]. Chandrakant Biradar et al proposed an algorithm to extract the tumor region from MRI images. They applied DWT to decompose an image. The author applied segmentation on DWT image to extract tumor region. They extracted the features like size; shape and texture to classify the type of tumor .they have used SVM classifier for classification [5]. Atiq Islam et al proposed an algorithm for segmentation of brain tumor MRI. Due to complex appearance of brain in MRI, author designed
  • 2. IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308 _______________________________________________________________________________________ Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 219 multiresolutionfractal technique to get multifractal features form tumor segmented images. The segmentation of proposed multiracial feature compared with Gabor features in this paper. The classification has been done by using multiracial features of tumor with the help of novel DiverseAdaBoost SVM classifier to improve tumor classification rate [6]. Meiyan Huang et al proposed the classification framework with the help of local independent projection into the classical classification model. The performance evaluation of proposed LIPC classifier had done by using two-spiral structure by authors. They also compared two classification techniques like SRC and Support Vector Machine (SVM) [7]. Dr. P.V. Ramaraju et al proposed an algorithm for classification of brain tumor. They have used MRI of brain to detect and classify a tumor. This algorithm is based on a wavelet transformation. The wavelet transformation is used to extract features from brain tumor MRI. Author has used feed forward probabilistic neural networks (PNN) to classify brain tumor based on these extracted features. They classified MRI of brain into benign, malignant or normal classes [8]. 3. PROPOSED METHODOLOGY The MRI of brain is represented here as a gray scale image. These gray scale images are having intensity levels ranging from 0-255, where 0 represents black color and 255 represents white color. Figure 1 shows a sample MRI of brain tumor from the data base used for this work. The database is of 72 brain MRI image. Figure.1.Brain Tumor MRI image The blood cells in brain are represented by white color and remaining portion of brain is represented by different gray color shade, whose intensity is less than 255 in MRI. Using this basic idea we have designed our algorithm to find out first order textural features from MRI of brain tumor and selection of exact classifier technique from the study of different classifiers based on the features. In this proposed algorithm MRI image of brain as are used as an input. These MRI images of brain are clearer than CT scan images. Figure 2 shows various stages that are followed for tumor declaration. The major blocks used are I. Preprocessing. II. Feature extraction III. Classification I. PREPROCESSING Input for proposed algorithm is a brain tumor image obtained from MRI. These images are not that much clear for tumor declaration. So preprocessing is the first step to make an input image more visible to human eye. At this stage to remove the blurriness of MRI images we have used median filter .Median filter remove the noise from MRI of brain tumor. Median filter gives a smooth image. After getting a smooth image, the next step is enhancement. The image enhancement increases sharpness of this filtered image. Here the enhancement of this filtered image has been done using power law transform. Power log transform gives sharper image then the input image. II. FEAURETURE EXTRAXTION Feature extraction is a stage where we have extracted the features from the sharpened image, which required as an input for classifier. In this algorithm we have used discrete cosine transformation (DWT). It is one of the types of wavelet transformation. In this algorithm, two level decomposition of „Symlet‟ DWT is used. This transform is applied to enhanced image. The DWT divides enhanced image into four regions using low pass filter and high pass filter bank and gives four different coefficients like absolute coefficient, diagonal coefficient, horizontal coefficient and vertical coefficient. The major information of an image is present in absolute coefficients as compare to remaining three regions. So we have selected absolute coefficients for feature extraction. We extracted different features like Contrast, Homogeneity, Correlation, Energy etc. These features are used as an input to classifier for tumor declaration. Figure.2. Block diagram of tumor declaration Tumor Declaration Image Acquisition Preprocessing Feature Extraction Classification
  • 3. IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308 _______________________________________________________________________________________ Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 220 III. CLASSIFICATION Classification is the essential step, where the brain tumor MRI classified into cancerous and noncancerous classes. The selection of a particular classifier is based on number of inputs and number of outputs to the classifier, features extracted from patterns as well as the type of input images. There are number of classifiers can be used to classify an images into different classes. Some classifiers are as follows. a. MULTILAYER PERCEPTRONS (MLP) Multilayer perceptron‟s are layered feed forward networks. These networks are mostly used for classification of an image into different classes. Multilayer perceptron‟s are useful in number of applications, where statistical classification is required. b. PRINCIPAL COMPONENT ANALYSIS (PCA) PCA is useful to approximate the original information with the help of least number of component .PCA is useful for approximating data with lower dimensional vectors. The PCA approach is based on eigenvectors, which is based on covariance matrix of an original image. By using PCA the test image was first identified by projecting the original image onto the eigen space to extract the corresponding set of weights and then the comparison has done with the help of a set of weights of an image in the training set [9]. c. SUPPORT VECTOR MACHINE (SVM) After feature extraction from an image, classification is the main task. The performance of classifier depends upon the number of features, samples. There are number of classifiers available for classification. SVM is one of the supervised classifier which gives good results in medical diagnosis. It gives better result in a high dimension feature space. SVM has also been applied on different real world problems such as face recognition, text categorization; cancer diagnosis .This SVM classifier gives better result for classification of binary MRI images [10]. d. PROBABLISTIC NEURAL NETWORK (PNN) Probabilistic Neural Network is the classifier that is useful for medical application. In some algorithms feature extraction has done with the help of GLCM and classification of images has done by using PNN. This classifier gives fast and accurate classification [11]. In proposed methodology MLP classifier has used its advantage is that it is easy to use and it can easily approximate any gray scale input or output map. The MATLAB and Nerosolution tools have been used for the classification of brain tumor MRI. 4. RESULT AND DISCUSSION In proposed algorithm classification of brain tumor has done using MLP. MLP verified these MRI input and classified it into Benign or Malignant tumor classes. Here MLP designed with number of hidden and output layers with different transfer functions and learning rules along with various percentages of training and testing data. Some sample results shown here are of three and five hidden layers and with different hidden layer transfer functions like TanhAxon, SigmoidAxon and LinearsigmoidAxon. The output layer transfer function is Sigmoid Axon. The learning rule at hidden layers and output layer is Levenbergmarqua. There are 29 different MLP combinations with their results shown here. This includes graph of mean square error (MSE) after three runs. The table which gives information regarding the minimum MSE, regression factor and percentage accuracy. By referring these results it‟s easy to verify a MLP network which gives accurate result by considering the conditions like true positive, false positive, true negative and false negative. 1. The results of MLP that designed with 50% database for training and 50%database for testing a network with three hidden layers has been shown in Figure 3 and Table 1. The TanhAxon function at hidden layer, Sigmoid Axon function at output layer and Levenberg learning rule has been used to design this MLP classifier. Figure.3. Average MSE with S.D.B. for three runs Table.1. Performance of MLP Best Networks Training Cross Validation Run # 1 2 Epoch # 999 999 Minimum MSE 0.006136364 1.77468E-09 Final MSE 0.006136364 1.79021E-09 Output / Desired Col1(1) Col1(0) Col1(1) 13 6 Col1(0) 5 14 -0.1 0 0.1 0.2 0.3 1 100 199 298 397 496 595 694 793 892 991 AverageMSE Epoch Average MSE with Standard Deviation Boundaries for 3 Runs Training + 1 Standard Deviation - 1 Standard Deviation Cross Validation
  • 4. IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308 _______________________________________________________________________________________ Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 221 Performance Col1(1) Col1(0) MSE 0.290002106 0.289712851 NMSE 1.163230668 1.162070435 MAE 0.290280969 0.289828325 Min Abs Error 2.99852E-08 8.58814E-08 Max Abs Error 1.009131705 1.004234283 r 0.420533115 0.421132249 Percent Correct 72.22222222 70 2. The results of MLP that designed with 50% database for training and 50%database for testing a network with three hidden layers has been shown in Figure 4 and Table 2. The Sigmoid Axon function at hidden layer, Sigmoid Axon function at output layer and Levenberg learning rule has been used to design this MLP classifier. Figure.4. Average MSE with S.D.B. for three runs Table.2. Performance of MLP Best Networks Training Cross Validation Run # 1 1 Epoch # 1000 1000 Minimum MSE 0.006136364 6.87844E-07 Final MSE 0.006136364 6.87844E-07 Output / Desired Col1(1) Col1(0) Col1(1) 12 5 Col1(0) 6 15 Performance Col1(1) Col1(0) MSE 0.284861912 0.284861912 NMSE 1.14261278 1.14261278 MAE 0.291762638 0.291762638 Min Abs Error 1.35502E-07 1.35502E-07 Max Abs Error 1.000821603 1.000821603 r 0.419999862 0.419999862 Percent Correct 66.66666667 75 3. The results of MLP that designed with 60% database for training and 40%database for testing a network with three hidden layers has been shown in Figure 5 and Table 3. The TanhAxon function at hidden layer, Sigmoid Axon function at output layer and Levenberg learning rule has been used to design MLP classifier. Figure.5. Average MSE with S.D.B. for three runs Table.3. Performance of MLP Best Networks Training Cross Validation Run # 1 1 Epoch # 727 6 Minimum MSE 0.009878049 0.000508521 Final MSE 0.009878049 0.101250136 Output / Desired Col1(0) Col1(1) Col1(0) 10 1 Col1(1) 5 14 Performance Col1(0) Col1(1) MSE 0.171753813 0.176993994 NMSE 0.68701525 0.707975976 MAE 0.208805816 0.204471573 Min Abs Error 0.01867669 0.003248765 Max Abs Error 0.98049437 0.996037063 r 0.657378803 0.655903134 Percent Correct 66.66666667 93.33333333 4. The results of MLP that designed with 70% database for training and 30%database for testing a network with three hidden layers has been shown in Figure 6 and Table 4.The TanhAxon function at hidden layer, Sigmoid Axon function at output layer and Levenberg learning rule has been used to design this MLP classifier. -0.1 0 0.1 0.2 0.3 0.4 1 100 199 298 397 496 595 694 793 892 991 AverageMSE Epoch Average MSE with Standard Deviation Boundaries for 3 Runs Training + 1 Standard Deviation - 1 Standard Deviation Cross Validation -0.1 0 0.1 0.2 0.3 0.4 0.5 1 100 199 298 397 496 595 694 793 892 991 AverageMSE Epoch Average MSE with Standard Deviation Boundaries for 3 Runs Training + 1 Standard Deviation - 1 Standard Deviation Cross Validation
  • 5. IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308 _______________________________________________________________________________________ Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 222 Figure.6. Average MSE with S.D.B.for three runs Table.4. Performance of MLP Best Networks Training Cross Validation Run # 1 1 Epoch # 1000 50 Minimum MSE 0.020663265 0.000487995 Final MSE 0.020663265 0.101249976 Output / Desired Col1(0) Col1(1) Col1(0) 8 1 Col1(1) 3 10 Performance Col1(0) Col1(1) MSE 0.159034196 0.16115271 NMSE 0.636136782 0.644610842 MAE 0.178435182 0.179954692 Min Abs Error 0.000593434 3.47955E-05 Max Abs Error 0.997620132 1.000161918 r 0.678696463 0.673600142 Percent Correct 72.72727273 90.90909091 5. The results of MLP that designed with 80% database for training and 20% database for testing a network with three hidden layers has been shown in Figure 7 and Table 5.The Linear SigmoidAxon function at hidden layer, Sigmoid Axon function at output layer and Levenberg learning rule has been used to design this MLP classifier. Figure.7. Average MSE with S.D.B.for three runs Table.5. Performance of MLP Best Networks Training Cross Validation Run # 1 3 Epoch # 141 4 Minimum MSE 0.038974871 5.52201E-05 Final MSE 0.038974871 0.074255015 Output / Desired Col1(1) Col1(0) Col1(1) 0 0 Col1(0) 9 6 Performance Col1(1) Col1(0) MSE 0.585828947 0.586106719 NMSE 2.440953948 2.442111331 MAE 0.597553803 0.597578527 Min Abs Error 0.011661897 0.011327293 Max Abs Error 0.988214604 0.98850352 r 0.681737659 0.681731578 Percent Correct 0 100 6. The results of MLP that designed with 50% database for training and 50%database for testing a network with five hidden layers. The TanhAxon function at hidden layer has been shown in Figure 8 and Table 6, Sigmoid Axon function at output layer and Levenberg learning rule has been used to design this MLP classifier. Figure.8. Average MSE with S.D.B. for three runs Table.6. Performance of MLP Best N Networks Training Cross Validation Run # 1 2 Epoch # 1000 10 Minimum MSE 0.018409091 0.004710426 Final MSE 0.018409091 0.101250078 Output / Desired Col1(1) Col1(0) Col1(1) 10 0 Col1(0) 5 23 0 0.05 0.1 0.15 0.2 0.25 1 100 199 298 397 496 595 694 793 892 991 AverageMSE Epoch Average MSE with Standard Deviation Boundaries for 3 Runs Training + 1 Standard Deviation - 1 Standard Deviation Cross Validation -0.2 -0.1 0 0.1 0.2 0.3 0.4 0.5 1 100 199 298 397 496 595 694 793 892 991 AverageMSE Epoch Average MSE with Standard Deviation Boundaries for 3 Runs Training + 1 Standard Deviation - 1 Standard Deviation Cross Validation -0.05 0 0.05 0.1 0.15 0.2 0.25 1 100 199 298 397 496 595 694 793 892 991 AverageMSE Epoch Average MSE with Standard Deviation Boundaries for 3 Runs Training + 1 Standard Deviation - 1 Standard Deviation Cross Validation
  • 6. IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308 _______________________________________________________________________________________ Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 223 Performance Col1(1) Col1(0) MSE 0.128431286 0.127960088 NMSE 0.537550078 0.535577877 MAE 0.209681988 0.206906826 Min Abs Error 0.02899802 0.026975136 Max Abs Error 0.934267124 0.936158062 r 0.721359045 0.722186609 Percent Correct 66.66666667 100 7. The results of MLP that designed with 60% database for training and 40%database for testing a network with five hidden layers has been shown in Figure 9 and Table 7. The SigmoidAxon function at hidden layer, Sigmoid Axon function at output layer and Levenberg learning rule has been used to design this MLP classifier. Figure.9. Average MSE with S.D.B. for three runs Table.7. Performance of MLP Best Networks Training Cross Validation Run # 1 1 Epoch # 999 1000 Minimum MSE 0.004939024 3.08311E-13 Final MSE 0.004939024 3.08311E-13 Output / Desired Col1(0) Col1(1) Col1(0) 15 6 Col1(1) 4 5 Performance Col1(0) Col1(1) MSE 0.333292125 0.333295741 NMSE 1.435229248 1.43524482 MAE 0.333314401 0.333316308 Min Abs Error 8.81615E-08 4.62701E-08 Max Abs Error 1.00002567 1.000022725 r 0.256671268 0.256665338 Percent Correct 78.94736842 45.45454545 8.The results of MLP designed with 70% database for training and 30% database for testing a network with five hidden layers has been shown in Figure10 and Table 8. The TanhAxon function at hidden layer, Sigmoid Axon function at output layer and Levenberg learning rule has been used to design this MLP classifier. Output / Desired Col1(1) Col1(0) Col1(1) 5 3 Col1(0) 3 11 Performance Col1(1) Col1(0) MSE 0.272784227 0.272809807 NMSE 1.178817554 1.178928093 MAE 0.272883818 0.272919695 Min Abs Error 2.91852E-06 1.71976E-06 Max Abs Error 1.000219309 1.000321875 r 0.410450333 0.410364346 Percent Correct 62.5 78.57142857 Figure.10. Average MSE with S.D.B. for three runs Table.8. Performance of MLP Best Networks Training Cross Validation Run # 1 2 Epoch # 1000 347 Minimum MSE 0.012397959 1.01311E-09 Final MSE 0.012397959 1.08339E-06 9. The results of MLP that designed with 70% database for training and 30%database for testing a network with five hidden layers has been shown in Figure 11 and Table 9. The Sigmoid Axon function at hidden layer, Sigmoid Axon function at output layer and Levenberg learning rule has been used to design this MLP classifier. Figure.11. Average MSE with S.D.B. for three runs -0.2 0 0.2 0.4 0.6 1 100 199 298 397 496 595 694 793 892 991 AverageMSE Epoch Average MSE with Standard Deviation Boundaries for 3 Runs Training + 1 Standard Deviation - 1 Standard Deviation Cross Validation -0.1 0 0.1 0.2 0.3 0.4 1 100 199 298 397 496 595 694 793 892 991 AverageMSE Epoch Average MSE with Standard Deviation Boundaries for 3 Runs Training + 1 Standard Deviation - 1 Standard Deviation Cross Validation -0.1 0 0.1 0.2 0.3 0.4 1 100 199 298 397 496 595 694 793 892 991 AverageMSE Epoch Average MSE with Standard Deviation Boundaries for 3 Runs Training + 1 Standard Deviation - 1 Standard Deviation Cross Validation
  • 7. IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308 _______________________________________________________________________________________ Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 224 Table.9. Performance of MLP Best Networks Training Cross Validation Run # 2 2 Epoch # 1000 1000 Minimum MSE 0.012397959 4.63139E-06 Final MSE 0.012397959 4.63139E-06 Output / Desired Col1(1) Col1(0) Col1(1) 9 3 Col1(0) 1 9 Performance Col1(1) Col1(0) MSE 0.187784297 0.187778004 NMSE 0.757396663 0.757371284 MAE 0.202055781 0.202035265 Min Abs Error 1.08352E-06 7.20899E-07 Max Abs Error 1.000000176 0.999999931 r 0.631840611 0.631864851 Percent Correct 90 75 10. The results of MLP that designed with 70% database for training and 30%database for testing a network with five hidden layers has been shown in Figure 12 and Table 10. The Linear Sigmoid Axon function at hidden layer, Sigmoid Axon function at output layer and Levenberg learning rule has been used to design this MLP classifier. Figure.12. Average MSE with S.D.B. for three runs Table.10. Performance of MLP Best Networks Training Cross Validation Run # 3 3 Epoch # 47 37 Minimum MSE 0.02637897 0.00013607 Final MSE 0.02637897 0.006843285 Output / Desired Col1(1) Col1(0) Col1(1) 9 4 Col1(0) 1 8 Performance Col1(1) Col1(0) MSE 0.120585703 0.12047363 NMSE 0.486362335 0.485910307 MAE 0.204653233 0.2023745 Min Abs Error 0.008063106 0.002503527 Max Abs Error 1.021844722 1.018708783 r 0.728278251 0.728898772 Percent Correct 90 66.66666667 11. The results of MLP that designed with 80% database for training and 20%database for testing a network with five hidden layers has been shown in Figure13 and Table 11. The Sigmoid Axon function at hidden layer, Linear Sigmoid Axon function at output layer and Levenberg learning rule has been used to design this MLP classifier. Figure.13. Average MSE with S.D.B. for three runs Table.11. Performance of MLP Best Networks Training Cross Validation Run # 3 1 Epoch # 53 30 Minimum MSE 0.028464595 0.005342038 Final MSE 0.028464595 0.005342053 Output / Desired Col1(1) Col1(0) Col1(1) 6 4 Col1(0) 2 3 Performance Col1(1) Col1(0) MSE 0.318735299 0.31873529 NMSE 1.280632897 1.280632863 MAE 0.4240641 0.424064103 Min Abs Error 0.088236967 0.088237001 Max Abs Error 0.911763033 0.911762999 r 0.188982237 0.188982237 Percent Correct 75 42.85714286 -0.05 0 0.05 0.1 0.15 0.2 0.25 0.3 1 100 199 298 397 496 595 694 793 892 991 AverageMSE Epoch Average MSE with Standard Deviation Boundaries for 3 Runs Training + 1 Standard Deviation - 1 Standard Deviation Cross Validation 0 0.1 0.2 0.3 0.4 0.5 1 100 199 298 397 496 595 694 793 892 991 AverageMSE Epoch Average MSE with Standard Deviation Boundaries for 3 Runs Training + 1 Standard Deviation - 1 Standard Deviation Cross Validation
  • 8. IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308 _______________________________________________________________________________________ Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 225 12. The results of MLP that designed with 90% database for training and 10%database for testing a network with five hidden layers has been shown in Figure 14 and Table 12. The Sigmoid Axon function at hidden layer, TanhAxon function at output layer and Levenberg learning rule has been used to design this MLP classifier. Figure.14. Average MSE with S.D.B. for three runs Table.12. Performance of MLP Best Networks Training Cross Validation Run # 2 2 Epoch # 1000 14 Minimum MSE 0.016071429 0.001209166 Final MSE 0.01607143 0.20251269 Output / Desired Col1(1) Col1(0) Col1(1) 5 1 Col1(0) 0 2 Performance Col1(1) Col1(0) MSE 0.141924775 0.142004327 NMSE 0.605545707 0.605885129 MAE 0.180090077 0.180807332 Min Abs Error 0.051770794 0.054609445 Max Abs Error 1.055553126 1.0555548 r 0.745347813 0.745351192 Percent Correct 100 66.66666667 13. The results of MLP that designed with 90% database for training and 10%database for testing a network with five hidden layers has been shown in Figure 15 and Table13. The Sigmoid Axon function at hidden layer, Sigmoid Axon function at output layer and Levenberg learning rule has been used to design this MLP classifier. Figure.15. Average MSE with S.D.B. for three runs Table.13. Performance of MLP Best Networks Training Cross Validation Run # 1 1 Epoch # 823 2 Minimum MSE 0.016071429 0.00125 Final MSE 0.016071429 0.101250941 Output / Desired Col1(1) Col1(0) Col1(1) 4 0 Col1(0) 0 4 Performance Col1(1) Col1(0) MSE 0.003086419 0.00308642 NMSE 0.012345676 0.012345679 MAE 0.05555555 0.055555555 Min Abs Error 0.055555544 0.055555555 Max Abs Error 0.055555556 0.055555555 r 1 1 Percent Correct 100 100 7. CONCLUSION The proposed algorithm for classification of brain tumor MRI image classified MRI images database effectively into benign tumor and malignant tumor with the help of MLP classifier. The MLP classifier used here with three and five number of hidden layers by using different hidden layer functions and output layer functions. By observing the above results, it‟s seen that MLP classifier is the best classifier for brain tumor MRI database. MLP classifier classified the database accurately at 90% database for training and 10%database for testing a network with five hidden layers, Sigmoid Axon function at hidden layer, Sigmoid Axon function at output layer with Levenberg learning rule. REFERNCES [1]Manoj K Kowar and Sourabh Yadav, 2012, “Brain Tumor Detction and Segmentation Using Histogram Thresholding” , International Journal of Engineering and -0.1 0 0.1 0.2 0.3 0.4 1 100 199 298 397 496 595 694 793 892 991 AverageMSE Epoch Average MSE with Standard Deviation Boundaries for 3 Runs Training + 1 Standard Deviation - 1 Standard Deviation Cross Validation -0.1 0 0.1 0.2 0.3 0.4 1 100 199 298 397 496 595 694 793 892 991 AverageMSE Epoch Average MSE with Standard Deviation Boundaries for 3 Runs Training + 1 Standard Deviation - 1 Standard Deviation Cross Validation
  • 9. IJRET: International Journal of Research in Engineering and Technology eISSN: 2319-1163 | pISSN: 2321-7308 _______________________________________________________________________________________ Volume: 04 Issue: 12 | Dec-2015, Available @ http://www.ijret.org 226 Advanced Technology (IJEAT) ISSN: 2249 – 8958, Volume-1, Issue-4, pp. 16-20 . [2] T. Logeswari and M. Karnan, 2010, “An improved implementation of brain tumor detection using segmentation based on soft computing”, Second International Conference on Communication Software and Networks, ICCSN10, pp. 147-151. [3] Shan Shen, William Sandham , 2005 , “ MRI Fuzzy Segmentation of Brain Tissue Using Neighborhood Attraction With Neural-Network Optimization ”, IEEE transactions on information technology in biomedicine Volume 9,issue no.3,pp. 459 -467. [4] Dina Aboul Dahab, Samy S. A. Ghoniemy, Gamal M. Selim, 2012, “Automated Brain Tumor Detection and Identification Using Image Processing and Probabilistic Neural Network Techniques”, International Journal of Image Processing and Visual communication, ISSN 2319- 1724 : Volume - 1 , Issue no.2 . [5]Chandrakant Biradar, Shantkumari, 2013, “Measurement based Human Brain Tumor Recognition by Adapting Support Vector Machine”, IOSR Journal of Engineering (IOSRJEN) e-ISSN: 2250-3021, pp. 2278-8719 Volume 3, Issue no.9, pp 26-31. [6] Atiq Islam, Syed M. S. Reza, and Khan M. , 2013 ,“Multifractal Texture Estimation for Detection and Segmentation of Brain Tumors ” , IEEE transactions on biomedical engineering Volume 60, no.11, pp.3204-3215 . [7]Meiyan Huang,Wei Yang, YaoWu, Jun Jiang,Wufan Chen ,2014, “Brain Tumor Segmentation Based on Local Independent Projection-Based Classification”, IEEE transactions on biomedical engineering , Volume 61,Issue no. 10, pp . 2633 -2645. [8]Dr.P.V.Ramaraju,Shaik Baji, 2014, “Brain Tumour classification, Detection and Segmentation Using Digital Image Processing and Probabilistic Neural Network Techniques”, International Journal of Emerging Trends in Electrical and Electronics (IJETEE – ISSN: 2320-9569) Volume 10, Issue no.10,pp. 15-20.. [9] Girja Sahu, Lalit Kumar, P. Bhaiya , 2014, “ A Survey Paper Based on the Classification of MRI Brain Images Using Soft Computing Techniques”, International Journal of Emerging Technology and Advanced Engineering Website: www.ijetae.com (ISSN 2250-2459, ISO 9001:2008 Certified Journal,) Volume 4, Issue no.12, pp.309-314. [10] Qurat-Ul-Ain , Ghazanfar Latif , Sidra Batool Kazmi , 2014, “ Classification and Segmentation of Brain Tumor using Texture Analysis ”, Recent Advances in Artificial Intelligence , Knowledge Engineering and Databases ISSN: 1790-5109 ISBN: 978-960-474-154-0, pp.147-155 . [11] Dr. P.V. Ramaraju and Shaik Baji , 2014, “Brain Tumour classification, Detection and Segmentation Using Digital Image Processing and Probabilistic Neural Network Techniques” , International Journal of Emerging Trends in Electrical and Electronics (IJETEE – ISSN: 2320-9569) Volume 10, Issue no. 10, pp.15-20.