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Essential to care



                    September 29, 2008
Forward-looking statements and
GAAP reconciliation
This presentation contains forward-looking statements addressing expected financial results of Cardinal Health, the planned spin-off of Cardinal
Health’s clinical and medical products businesses as a separate company, the expected financial results of the new company and of Cardinal Health
after giving effect to the spin-off of the new company, the operation, business and prospects of Cardinal Health and the new company following the
planned spin-off and other expectations, prospects, estimates and other matters that are dependent upon future events or developments. These
matters are subject to risks and uncertainties that could cause actual results to differ materially from those projected, anticipated or implied. These
risks and uncertainties include uncertainties regarding the planned spin-off of the clinical and medical products businesses as a new stand-alone
entity, including the timing and terms of any such spin-off and whether such spin-off will be completed, and uncertainties regarding the impacts on
Cardinal Health, the new clinical and medical products company and the market for their respective securities if the spin-off is accomplished. In
addition, Cardinal Health and the proposed new clinical and medical products company are subject to additional risks and uncertainties described in
Cardinal Health's Form 10-K, Form 10-Q and Form 8-K reports (including all amendments to those reports) and exhibits to those reports, including
(but not limited to) the following: competitive pressures in Cardinal Health’s various lines of business; the loss of one or more key customer or supplier
relationships or changes to the terms of those relationships; uncertainties relating to timing of generic and branded pharmaceutical introductions and
the frequency or rate of branded pharmaceutical price appreciation or generic pharmaceutical price deflation; changes in the distribution patterns or
reimbursement rates for health-care products and/or services; the results, consequences, effects or timing of any inquiry or investigation by any
regulatory authority or any legal or administrative proceedings; future actions of regulatory bodies or government authorities relating to Cardinal
Health’s manufacturing or sale of products and other costs or claims that could arise from its manufacturing, compounding or repackaging operations
or from its other services; difficulties and uncertainties related to the integration of acquired businesses; and conditions in the pharmaceutical market
and general economic and market conditions. This presentation reflects management’s views as of September 29, 2008. Except to the extent
required by applicable law, Cardinal Health undertakes no obligation to update or revise any forward-looking statement. Cardinal Health presents
non-GAAP earnings from continuing operations (and presentations derived from this financial measure, including per share calculations) on a
forward-looking basis. Non-GAAP diluted EPS from continuing operations is calculated by dividing earnings from continuing operations, excluding
special items and impairments, (gain)/loss on sale of assets and other, net, both net of tax, by diluted weighted average shares outstanding. The
most directly comparable forward-looking GAAP measure is earnings from continuing operations. Cardinal Health is unable to provide a quantitative
reconciliation of this forward-looking non-GAAP measure to the most directly comparable forward-looking GAAP measure, because the company
cannot reliably forecast special items and impairments, (gain)/loss on sale of assets and other, net, which are difficult to predict and estimate. Please
note that the unavailable reconciling items could significantly impact Cardinal Health's future financial results.




                                                                                                                                                 2
Creating SpinCo:
Decision to spin-off CMP
Disciplined review process and rationale

 •   Disciplined review involving Board of Directors, executive
     leadership team and experienced external advisors
 •   Separation of businesses will better position each to realize its
     long-term potential
      −   Sharper strategic vision and enhanced management focus
      −   Enhanced ability to make investments in respective growth areas
      −   Improved opportunities to access / allocate capital
      −   Better alignment of management / employee incentives and rewards
 •   One-time costs and potential dis-synergies are manageable
      −   Separation, transaction and stand-up costs
      −   Public company infrastructure
      −   Planned services agreements
      −   Hospital selling efforts
           • Significant scale in each business
           • Analyzing collaboration/partnering alternatives


                                                                             4
Steps to completion
• File Form 10 Registration Statement for SpinCo with
  SEC in Q3FY09 (est.)
   – SEC will declare Form 10 effective when review complete
• Seek confirmation on the tax-free nature of the
  transaction from appropriate authorities
• Complete separation and related agreements
• Board declares pro rata distribution of SpinCo stock
  to Cardinal Health shareholders, sets record date /
  payment date / distribution ratio when final process
  is complete
   – Information statement mailed to CAH shareholders


                                                               5
Capital structure and capital deployment
• We plan to:
   – For Cardinal Health in FY09:
      • Share repurchases to no more than offset equity compensation
        issuances
      • Continue regular $0.14 quarterly dividend until the spin-off
        is completed

   – For Cardinal Health Post-Spin-off:
      • Have a balance sheet, financial policies and credit metrics
        commensurate with investment-grade credit ratings
      • Continue to pay a dividend

   – For SpinCo:
      • Have a balance sheet, financial policies and credit metrics
        commensurate with investment-grade credit ratings
      • Not pay dividends, but instead reinvest in R&D


                                                                       6
Leadership teams


                                                               SpinCo
                 Cardinal
                                                          Clinical and Medical
                  Health                                        Products




CEO:                                        CEO:
  George Barrett, ~25 years in healthcare     Dave Schlotterbeck, ~14 years in healthcare
CFO:                                        COO (Chief Operating Officer):
  Jeff Henderson, ~10 years in healthcare     Dwight Winstead, ~30 years in healthcare
CEO, pharmacy supply chain solutions*:      CFO:
  Mike Kaufmann, ~17 years in healthcare      Outside search in process
CEO, medical / surgical solutions*:
  Mike Lynch, ~24 years in healthcare

                                               *Official business names to be determined at later date.

                                                                                                 7
Business structure

            Cardinal Health (RemainCo)                                              SpinCo

       Healthcare Supply Chain Services (HSCS)                 Clinical and Medical Products (CMP)
       Pharmaceutical Supply Chain*                             Clinical Technologies
       Medical Supply Chain - U.S.                                   • Infusion Technologies
           • Hospital Supply                                         • Dispensing Technologies
           • Ambulatory Care                                         • Supply Technologies
           • Scientific Products (Laboratory)                   Clinical Services
                                                                Respiratory / Neurocare
       Specialty / Nuclear Pharmacy
                                                                Infection Prevention
       Presource
                                                                     • Skin Prep Solutions (includes Enturia)
       Cardinal Health – Canada
                                                                International (excl. Canada and Puerto Rico)
       Cardinal Health – Puerto Rico (including
         Borschow)                                               Medical Specialties (surgical products)
                                                                     • V. Mueller / On-site Services
       Martindale
                                                                     • Interventional Specialties


       Fluid management
       Convertors (drapes, gowns)
       Gloves (exam and surgical)



       Pharmacy Services**
       Medicine Shoppe International**



                      *Includes Specialty Distribution
                      **Cardinal Health is continuing to conduct an analysis of Pharmacy Services and Medicine Shoppe International
                      to evaluate their future strategic fit.                                                                       8
Cardinal Health post-spin
    Business portfolio
            Improve healthcare productivity, quality and efficiency through our
           superior supply chain execution and innovative products and services

                   Pharma                                                                                         U.S. / Canada
                                                          Cardinal Health
                      and                                                                                          Med Supply
                                                                 Post-Spin
                   Specialty                                                                                       Distribution
                  distribution

                                                            >$90B FY09 pro                                   Operating
                                                            forma revenue*
                              Nuclear/                                                                      Room related
                              Specialty                                                                      products/
                              Pharma                                                                          services


                                                                                       Medicine
                                                 Pharmacy
                                                                                       Shoppe
                                                 Services**
**Cardinal Health is continuing to
                                                                                        Int’l**
conduct an analysis of Pharmacy
Services and Medicine Shoppe
International to evaluate their
future strategic fit.
                                     *An estimate of the pro forma revenue for fiscal 2009 in accordance with generally accepted accounting principles
                                     with adjustments expected to reflect each company as a stand-alone entity. The estimate is based on assumptions
                                     that management currently believes are reasonable, but actual revenue may vary materially from the estimate.
                                                                                                                                           9
SpinCo business portfolio
         Improving lives through better technology
                     at the point of care


                                              SpinCo                                      Respiratory and
     Infusion
                                                                                            Neurocare
                                       Clinical and Medical
                                             Products

                                                                                                  Medical
                                         >$4B FY09 pro                                           Specialties
    Dispensing                           forma revenue*
                                                                                                   (surgical
                                                                                                   products)


                                                                              Infection
                 Clinical
                                                                             Prevention
                 Services

                  *An estimate of the pro forma revenue for the 12 months ended June 30, 2009 in accordance with generally
                  accepted accounting principles with adjustments expected to reflect each company as a stand-alone entity.
                  The estimate is based on assumptions that management currently believes are reasonable, but actual
                  revenue may vary materially from the estimate.                                                       10
Key milestones

Aug. 7, 2008         Announcement of exploration
Sept. 29, 2008       Announcement of Board decision to pursue
Oct. 29, 2008        Q1 FY09 earnings
Nov. 5, 2008         Annual shareholder meeting
Q3 FY09              Expected Form 10 filing
May 8, 2009          Annual analyst & investor day
Q4 FY09?             Expected record date
Q4 FY09 / Q1 FY10?   Expected effective date




                                                            11
Why invest in current Cardinal Health?


  Two industry-leading businesses …
  With talented, experienced management …
  Well-positioned to drive future growth …
  With a focus on and commitment to ...
  Delivering value to shareholders.



                                             12
The Landscape:
    U.S. healthcare costs are rising at alarming rate
                                                              National Health Expenditures per Capita
                                                                            (1990-2016)                             $12,782
                                      $14,000
                                                                                                                     (2016)
•    US projected to spend over       $12,000
     $2.2 trillion on healthcare in
     2007 (16.2% of GDP)              $10,000
                                                                                          $7,498
                                                                                          (2007)
                                       $8,000


•    Healthcare spending has           $6,000

     risen at a rate 2.4% faster                 $2,813
                                       $4,000
     than GDP since 1970                         (1990)
                                                                                                  Per Capita
                                                                                                  Projected Per Capita
                                       $2,000


•    CMS estimates that by                $0

     2016 US healthcare                    90

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     spending will nearly double,         Note: Figures from 1990 through 2005 represent historical data; data from 2006-
                                          2016 are projected.
     exceeding $4.1 trillion              Source: Centers for Medicare and Medicaid Services, Office of the Actuary, National
                                          Health Statistics Group, at http://www.cms.hhs.gov/NationalHealthExpendData/
                                          (Historical data from NHE summary including share of GDP, CY 1960-2005, file
                                          nhegdp05.zip; Projected data from NHE Projections 2006-2016, Forecast summary
                                          and selected tables, file proj2006.pdf).




                                                                                                                   13
The Landscape:
Errors and inefficiencies plague the system


                                Overall healthcare
            Breast cancer
                                 in U.S. (RAND)
            screening (65-69)
                                               Adverse drug events
          1,000,000
                                                         Hospital-acquired infections
Defects    100,000
  per                                                              Airline baggage handling
            10,000
million
             1,000                                                          Anesthesia-related
                                                                            fatality rate
               100
                                                                               U.S. industry
                10                                                             Best-in-Class
                           1     2        3          4         5        6
                 1

                                          σ levels
            However, history suggests these errors can be prevented
                                                                                Source: C. Buck, GE, 2007


                                                                                            14
Cardinal Health (Post-Spin)
Cardinal Health post-spin
    Business portfolio
            Improve healthcare productivity, quality and efficiency through our
           superior supply chain execution and innovative products and services

                   Pharma                                                                                            U.S. / Canada
                                                            Cardinal Health
                      and                                                                                             Med Supply
                                                                   Post-Spin
                   Specialty                                                                                          Distribution
                  distribution

                                                              >$90B FY09 pro                                    Operating
                                                              forma revenue*
                              Nuclear/                                                                         Room related
                              Specialty                                                                         products/
                              Pharma                                                                             services


                                                                                         Medicine
                                                   Pharmacy
                                                                                         Shoppe
                                                   Services**
**Cardinal Health is continuing to                                                        Int’l**
conduct an analysis of Pharmacy
Services and Medicine Shoppe
International to evaluate their
future strategic fit.
                                     *An estimate of the pro forma revenue for fiscal 2009 in accordance with generally accepted accounting principles with
                                     adjustments expected to reflect each company as a stand-alone entity. The estimate is based on assumptions that
                                     management currently believes are reasonable, but actual revenue may vary materially from the estimate.
                                                                                                                                              16
The Business Case:
Significant footprint and scale
 • 90% of U.S. hospitals use our products or services
 • More than 50,000 deliveries are made each day to 40,000
   customer sites in U.S.
 • Leading distributor of U.S. prescriptions, medical/surgical
   and lab products through our system
 • Largest U.S. nuclear pharmacy provider, with more than 13
   million prescriptions dispensed each year
 • Largest provider of products / services to acute care
   hospitals in North America




                                                            17
Our value proposition

• Large, deep and broad footprint across health channels
   – Retail, hospital, sub-acute, mail-order, ambulatory


• Provide products / services that empower doctors,
  pharmacists and nurses to focus on what’s most
  important − patients


• Our scale and breadth position us to help reduce costs,
  improve quality and outcomes, and satisfy needs across
  the healthcare system


                                                           18
Growth drivers

• Pressure on healthcare system to be more
  accessible, more productive, higher quality and safer
• Demographics – aging population demands more
  health care products / services
• Increasing use of generic pharmaceuticals
• Opportunities to increase formulary-type Cardinal
  Health private label programs
• Strong positioning in all retail channels
• Highly efficient cost structure



                                                          19
We provide valuable solutions throughout the
    pharma distribution channel
                                                Aligning offerings
Suppliers                                                                                               Customers

                       Generic                  Retail Independents            Chains/                   Hospital
Branded
                                                                               Warehousing and
                       •   Market share         •   Pharmaceutical/                                      •   Pharma
•   Inventory mgt
                                                    distribution services                                    distribution
                                                                               Non-warehousing
                       •   Launch speed
•   Data reporting
                                                •   Pharmacy brands                                      •   Medication
                       •   Contract mgt
•   High service                                                               •Distribution /
                                                •   Leader® brand                                            packaging
    levels                                                                     operational excellence
                       •   Efficient reach to
                                                •   Rx purchasing                                        •   Fluid
                           every COT
•   Contract mgt                                                               •Ordering / inventory
                                                    programs                                                 management
                                                                               management
                       •   AR / returns mgt
•   AR / returns mgt
                                                                                                             products
                                                •   FirstScript – customized
                                                                               •Purchasing solutions
                       •   Centralized
•   Special handling
                                                    Autoshipment to stock                                •   Infection
                           shipping                                            •SOURCE generics
•   Centralized                                     new brand or generic                                     prevention
                                                                               (primary and back-up
                       •   Data reporting
    shipping                                        items fast                                               (gloves,
                                                                               formulary)                    convertors)
•   Efficient reach                             •   Front-end purchasing &
                                                                               •Home health care,
    to every COT                                    merchandising                                        •   Surgical kitting
                                                                               packaging, FirstScript
                                                •   Managed care                                         •   Consulting/
                                                                               •Managed care
                                                    programs                                                 design
                                                                                                             services
                                                •   Ordering / inventory
                                                    management




                                                                                                                       20
For example…
Improving reimbursements                                    Creating alternate revenue streams
  Leader® improves reimbursements by taking                   Leader® creates alternate revenue streams
  the guesswork out of dealing with PBMs,                     such as home healthcare, durable medical
  providing reimbursement support, protecting                 equipment and diabetes management to
  margins and providing reassurances that each                solidify an independent pharmacy as a
  claim is submitted and collected properly.                  community’s complete healthcare destination.



                                                    Retail
                                            Independent Pharmacy
                                              “CEO” = Pharmacist



                                                            Increasing marketshare
Streamlining operations
  Leader® streamlines operations through                      Leader® increases market share and
  proactive inventory management and addressing               establishes strong brand recognition by
                                                              optimizing advertising strategies,
  workflow issues related to staffing shortages, high
                                                              implementing effective store signage and
  labor costs, increasing scripts, decreasing margins
                                                              providing a profitable private label line.
  and patient safety requirements.



                                                                                                      21
And we provide valuable solutions throughout
the medical/surgical distribution channel
•   Leading position in acute care

•   Meaningful presence in lab setting

•   Focused on critical areas of hospital from quality
    and economic standpoint
    –   Operating room – Presource®, convertors, fluid
        management, gloves
    –   Cardiac imaging – nuclear pharmacy

•   Increasing position in ambulatory/alternate sites as
    care moves out of acute care setting


                                                           22
For example…

Logistics and replenishment                             Product Portfolio
  Valuelink – leading just-in-time inventory solution     Broad portfolio of brand / proprietary products
  Optifreight – help customers manage freight costs       Expanding private label line
  Custom solutions




                                         Hospital
                                 CEO/COO/Head of Purchasing




Operational improvements                                Kitting
  Order-to-cash and SG&A                                  Presource® - product
                                                          offerings tailored to customer
                                                          needs to improve supply
                                                          chain management




                                                                                                  23
FY09 priorities and key initiatives



                       Improve the quality and
                      productivity of healthcare
Invest and            Sweeten our          Innovate to          Rebuild a
execute               mix (customer        improve              winning
flawlessly to         and product)         customer             culture
build core                                 loyalty by
capabilities                               segment



                Enabled through information, insight and technology



                                                                            24
Near-term performance indicators

 •   Increase direct-store-door sales
 •   Resolve anti-diversion challenges
 •   Increase proprietary generic Source
     program sales
 •   Maintain U.S. medical distribution
     momentum and grow the private label




                                           25
SpinCo
SpinCo business portfolio
         Improving lives through better technology
                     at the point of care


                                              SpinCo                                      Respiratory and
     Infusion
                                                                                            Neurocare
                                       Clinical and Medical
                                             Products

                                                                                                  Medical
                                         >$4B FY09 pro                                           Specialties
    Dispensing                           forma revenue*
                                                                                                  (surgical
                                                                                                  products)


                                                                              Infection
                 Clinical
                                                                             Prevention
                 Services

                  *An estimate of the pro forma revenue for the 12 months ended June 30, 2009 in accordance with generally
                  accepted accounting principles with adjustments expected to reflect each company as a stand-alone entity. The
                  estimate is based on assumptions that management currently believes are reasonable, but actual revenue may
                  vary materially from the estimate.                                                                   27
Quality and patient safety issues abound

                                                 Annual Serious Adverse Events in
 •   Hospital costs alone from adverse              a Typical 300-Bed Hospital
     drug events are estimated at $3-6B
      –   Excludes costs associated with
          patient injury and legal claims


 •   Hospital infections add an estimated
     $30B to the nation’s hospital costs
     annually
 •   Costs are largely borne by the
     providers, payers, and government



          CMP is uniquely focused
      on addressing the top 3 hospital
                                            Sources: Solucient, First Consulting Group, 2004
           patient safety issues



                                                                                               28
CMP is uniquely positioned to focus on
key issues…

      Improve           • Integrating our offers and knowledge to manage all medications
     medication
                        • Uniquely positioned to improve safety and productivity
    management

                        • Established role and presence in the surgical suite
 Enhance infection
                        • Expansion into the large respiratory market
    prevention
                        • Focus on protocol compliance and clinically differentiated products


                        • Expanding our capability with high impact procedures
  Minimize risk and
 cost of procedures     • Tackling our customers latest concerns


   Help hospitals       • Leading market offering in infection detection
 identify patients at
                        • Building our data to address top hospital concerns
         risk




                                                                                        29
…with industry leading positions

• Global leader in medication safety and infusion systems
• Largest U.S. hospital footprint in dispensing systems
• Largest acute-care respiratory company worldwide
• Industry’s most comprehensive medication management
  solution
• Leader in hospital-acquired infection (HAI) prevention
• Leader in positive patient identification
• Leader in U.S. surgical instrumentation



                                                            30
In key product areas, critical to care…

                           Infusion



                                           Ventilation




                              Surgical
              Infection
                             instruments
             Prevention
Dispensing




                                                         31
…such as dispensing, where we have a
significant portion of the installed U.S. base
 •   Significantly outperform competition                Dispensing revenue
      – Revenue growth
      – Operating margin
 •   Strong domestic demand
      – Committed contracts and strong backlog
        provide continuous momentum
                                                                     CAH
      – Consistent, high renewal rate
 •   Next generation innovation and
     integrated offerings

                                                     Competitor 1                  Competitor 2                 CAH



                                                 Cardinal Health data analysis; data extrapolated from earnings releases.




                    Renewal rates on 5-year leases are 95 – 99%


                                                                                                                    32
And infusion, where we took >60% of
business from competition in FY08
• Continued both premium pricing / gains in placements
   – 37% of U.S. installed base
   – 63% of U.S. placements


• Strong international expansion
   – Expanded manufacturing capacity
   – Exceeding our expectation

 Disposable contracts create 5-year annuity stream for infusion pumps


                                                                 33
Combined with being world’s largest
acute-care respiratory company
•   Industry leadership
     – Ventilation leader - 50% growth in VIASYS installed base in past
       3 years
     – Leading cardiopulmonary testing platform
•   Leading innovator
     – Leading technology in ventilation (critical care & portable)
       and diagnostics (respiratory & sleep)
     – Innovative offerings that address ventilator-associated
       pneumonia
     – Over 200 active patents, 300 engineers and credentialed
       clinicians
•   Unique breadth
     – Capital equipment and disposables for adult, pediatric, neonatal,
       invasive, non-invasive, nCPAP, high-frequency
     – Continuum of offerings beyond hospital setting
     – VIASYS adds strong international channel



                                                                           34
And a strong player in infection prevention,
with next-generation products
• Innovation
   – Leading-edge infection prevention continuum in development
• Revenue expansion
   – Expanding demand for infection detection and prevention
   – Enturia acquisition
   – International penetration
• Margin expansion
   – Mix-shift in base products
   – Operational Excellence/Lean
   – Flexible manufacturing/sourcing model



                                                                  35
CMP (SpinCo) key near- to mid-term priorities

1   Drive innovation and clinical differentiation
     –   R&D pipeline is loaded − expecting to launch ~45-50 new products
         and enhanced solutions over the next 18 months

2   Use industry leading positions to accelerate growth
     –   Grow international sales by expanding country specific strengths

3   Successfully complete integrations (VIASYS and Enturia)
     –   Cost and revenue synergies
     –   Respiratory business model transformation

    Continue rounding out our solutions
4
     –   Expand organically through product and solution innovation
     –   Strategic tuck-ins




                                                                        36
Total Company Priorities
Total company FY 2009 priorities
 •   Achieve FY09 operational and financial objectives
 •   Resolve outstanding regulatory issues
 •   Enhanced investment in R&D and IT
 •   Return HSCS to steady growth
 •   Successfully complete integrations (VIASYS, Enturia,
     Borschow)
 •   Efficiently execute a spin-off of the CMP businesses,
     while minimizing disruption



                                                         38
FY09 financial goals


                                  August 7, 2008

Total revenue growth:
                                           6-7%


Non-GAAP EPS1:                             $3.80 - $3.95
                                                    Revenue                       Profit
Segment                                             Growth                       Growth

Healthcare Supply Chain Services (HSCS)               >6%                      Flat to (5%)


Clinical and Medical Products (CMP)                  >10%                         >20%



                              1 Non-GAAP   diluted earnings per share from continuing operations
                                                                                               39
FY09 assumptions update
•   Capital deployment
     – Share repurchases to no more than offset equity compensation
       issuances
     – Continue regular $0.14 quarterly dividend until spin-off is completed
•   Portfolio rationalization/review
     – MedSystems sale closed 8/29/08
     – Tecomet sale closed 9/26/08
     – Review of MSI and Pharmacy Services ongoing
•   Special items and/or other expenses / charges related to spin-off
    not included in guidance
     – Anticipate a significant portion of costs related to spin-off may be
       classified as special items in accordance with company practices


                                                                               40
Summary: So why invest in current
Cardinal Health now?

  Two industry-leading businesses …
  With talented, experienced management …
  Well-positioned to drive future growth …
  With a focus on and commitment to ...
  Delivering value to shareholders.



                                             41
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cardinal health Conference Call Presentation

  • 1. Essential to care September 29, 2008
  • 2. Forward-looking statements and GAAP reconciliation This presentation contains forward-looking statements addressing expected financial results of Cardinal Health, the planned spin-off of Cardinal Health’s clinical and medical products businesses as a separate company, the expected financial results of the new company and of Cardinal Health after giving effect to the spin-off of the new company, the operation, business and prospects of Cardinal Health and the new company following the planned spin-off and other expectations, prospects, estimates and other matters that are dependent upon future events or developments. These matters are subject to risks and uncertainties that could cause actual results to differ materially from those projected, anticipated or implied. These risks and uncertainties include uncertainties regarding the planned spin-off of the clinical and medical products businesses as a new stand-alone entity, including the timing and terms of any such spin-off and whether such spin-off will be completed, and uncertainties regarding the impacts on Cardinal Health, the new clinical and medical products company and the market for their respective securities if the spin-off is accomplished. In addition, Cardinal Health and the proposed new clinical and medical products company are subject to additional risks and uncertainties described in Cardinal Health's Form 10-K, Form 10-Q and Form 8-K reports (including all amendments to those reports) and exhibits to those reports, including (but not limited to) the following: competitive pressures in Cardinal Health’s various lines of business; the loss of one or more key customer or supplier relationships or changes to the terms of those relationships; uncertainties relating to timing of generic and branded pharmaceutical introductions and the frequency or rate of branded pharmaceutical price appreciation or generic pharmaceutical price deflation; changes in the distribution patterns or reimbursement rates for health-care products and/or services; the results, consequences, effects or timing of any inquiry or investigation by any regulatory authority or any legal or administrative proceedings; future actions of regulatory bodies or government authorities relating to Cardinal Health’s manufacturing or sale of products and other costs or claims that could arise from its manufacturing, compounding or repackaging operations or from its other services; difficulties and uncertainties related to the integration of acquired businesses; and conditions in the pharmaceutical market and general economic and market conditions. This presentation reflects management’s views as of September 29, 2008. Except to the extent required by applicable law, Cardinal Health undertakes no obligation to update or revise any forward-looking statement. Cardinal Health presents non-GAAP earnings from continuing operations (and presentations derived from this financial measure, including per share calculations) on a forward-looking basis. Non-GAAP diluted EPS from continuing operations is calculated by dividing earnings from continuing operations, excluding special items and impairments, (gain)/loss on sale of assets and other, net, both net of tax, by diluted weighted average shares outstanding. The most directly comparable forward-looking GAAP measure is earnings from continuing operations. Cardinal Health is unable to provide a quantitative reconciliation of this forward-looking non-GAAP measure to the most directly comparable forward-looking GAAP measure, because the company cannot reliably forecast special items and impairments, (gain)/loss on sale of assets and other, net, which are difficult to predict and estimate. Please note that the unavailable reconciling items could significantly impact Cardinal Health's future financial results. 2
  • 4. Disciplined review process and rationale • Disciplined review involving Board of Directors, executive leadership team and experienced external advisors • Separation of businesses will better position each to realize its long-term potential − Sharper strategic vision and enhanced management focus − Enhanced ability to make investments in respective growth areas − Improved opportunities to access / allocate capital − Better alignment of management / employee incentives and rewards • One-time costs and potential dis-synergies are manageable − Separation, transaction and stand-up costs − Public company infrastructure − Planned services agreements − Hospital selling efforts • Significant scale in each business • Analyzing collaboration/partnering alternatives 4
  • 5. Steps to completion • File Form 10 Registration Statement for SpinCo with SEC in Q3FY09 (est.) – SEC will declare Form 10 effective when review complete • Seek confirmation on the tax-free nature of the transaction from appropriate authorities • Complete separation and related agreements • Board declares pro rata distribution of SpinCo stock to Cardinal Health shareholders, sets record date / payment date / distribution ratio when final process is complete – Information statement mailed to CAH shareholders 5
  • 6. Capital structure and capital deployment • We plan to: – For Cardinal Health in FY09: • Share repurchases to no more than offset equity compensation issuances • Continue regular $0.14 quarterly dividend until the spin-off is completed – For Cardinal Health Post-Spin-off: • Have a balance sheet, financial policies and credit metrics commensurate with investment-grade credit ratings • Continue to pay a dividend – For SpinCo: • Have a balance sheet, financial policies and credit metrics commensurate with investment-grade credit ratings • Not pay dividends, but instead reinvest in R&D 6
  • 7. Leadership teams SpinCo Cardinal Clinical and Medical Health Products CEO: CEO: George Barrett, ~25 years in healthcare Dave Schlotterbeck, ~14 years in healthcare CFO: COO (Chief Operating Officer): Jeff Henderson, ~10 years in healthcare Dwight Winstead, ~30 years in healthcare CEO, pharmacy supply chain solutions*: CFO: Mike Kaufmann, ~17 years in healthcare Outside search in process CEO, medical / surgical solutions*: Mike Lynch, ~24 years in healthcare *Official business names to be determined at later date. 7
  • 8. Business structure Cardinal Health (RemainCo) SpinCo Healthcare Supply Chain Services (HSCS) Clinical and Medical Products (CMP) Pharmaceutical Supply Chain* Clinical Technologies Medical Supply Chain - U.S. • Infusion Technologies • Hospital Supply • Dispensing Technologies • Ambulatory Care • Supply Technologies • Scientific Products (Laboratory) Clinical Services Respiratory / Neurocare Specialty / Nuclear Pharmacy Infection Prevention Presource • Skin Prep Solutions (includes Enturia) Cardinal Health – Canada International (excl. Canada and Puerto Rico) Cardinal Health – Puerto Rico (including Borschow) Medical Specialties (surgical products) • V. Mueller / On-site Services Martindale • Interventional Specialties Fluid management Convertors (drapes, gowns) Gloves (exam and surgical) Pharmacy Services** Medicine Shoppe International** *Includes Specialty Distribution **Cardinal Health is continuing to conduct an analysis of Pharmacy Services and Medicine Shoppe International to evaluate their future strategic fit. 8
  • 9. Cardinal Health post-spin Business portfolio Improve healthcare productivity, quality and efficiency through our superior supply chain execution and innovative products and services Pharma U.S. / Canada Cardinal Health and Med Supply Post-Spin Specialty Distribution distribution >$90B FY09 pro Operating forma revenue* Nuclear/ Room related Specialty products/ Pharma services Medicine Pharmacy Shoppe Services** **Cardinal Health is continuing to Int’l** conduct an analysis of Pharmacy Services and Medicine Shoppe International to evaluate their future strategic fit. *An estimate of the pro forma revenue for fiscal 2009 in accordance with generally accepted accounting principles with adjustments expected to reflect each company as a stand-alone entity. The estimate is based on assumptions that management currently believes are reasonable, but actual revenue may vary materially from the estimate. 9
  • 10. SpinCo business portfolio Improving lives through better technology at the point of care SpinCo Respiratory and Infusion Neurocare Clinical and Medical Products Medical >$4B FY09 pro Specialties Dispensing forma revenue* (surgical products) Infection Clinical Prevention Services *An estimate of the pro forma revenue for the 12 months ended June 30, 2009 in accordance with generally accepted accounting principles with adjustments expected to reflect each company as a stand-alone entity. The estimate is based on assumptions that management currently believes are reasonable, but actual revenue may vary materially from the estimate. 10
  • 11. Key milestones Aug. 7, 2008 Announcement of exploration Sept. 29, 2008 Announcement of Board decision to pursue Oct. 29, 2008 Q1 FY09 earnings Nov. 5, 2008 Annual shareholder meeting Q3 FY09 Expected Form 10 filing May 8, 2009 Annual analyst & investor day Q4 FY09? Expected record date Q4 FY09 / Q1 FY10? Expected effective date 11
  • 12. Why invest in current Cardinal Health? Two industry-leading businesses … With talented, experienced management … Well-positioned to drive future growth … With a focus on and commitment to ... Delivering value to shareholders. 12
  • 13. The Landscape: U.S. healthcare costs are rising at alarming rate National Health Expenditures per Capita (1990-2016) $12,782 $14,000 (2016) • US projected to spend over $12,000 $2.2 trillion on healthcare in 2007 (16.2% of GDP) $10,000 $7,498 (2007) $8,000 • Healthcare spending has $6,000 risen at a rate 2.4% faster $2,813 $4,000 than GDP since 1970 (1990) Per Capita Projected Per Capita $2,000 • CMS estimates that by $0 2016 US healthcare 90 92 94 96 98 00 02 04 06 08 10 12 14 16 19 19 19 19 19 20 20 20 20 20 20 20 20 20 spending will nearly double, Note: Figures from 1990 through 2005 represent historical data; data from 2006- 2016 are projected. exceeding $4.1 trillion Source: Centers for Medicare and Medicaid Services, Office of the Actuary, National Health Statistics Group, at http://www.cms.hhs.gov/NationalHealthExpendData/ (Historical data from NHE summary including share of GDP, CY 1960-2005, file nhegdp05.zip; Projected data from NHE Projections 2006-2016, Forecast summary and selected tables, file proj2006.pdf). 13
  • 14. The Landscape: Errors and inefficiencies plague the system Overall healthcare Breast cancer in U.S. (RAND) screening (65-69) Adverse drug events 1,000,000 Hospital-acquired infections Defects 100,000 per Airline baggage handling 10,000 million 1,000 Anesthesia-related fatality rate 100 U.S. industry 10 Best-in-Class 1 2 3 4 5 6 1 σ levels However, history suggests these errors can be prevented Source: C. Buck, GE, 2007 14
  • 16. Cardinal Health post-spin Business portfolio Improve healthcare productivity, quality and efficiency through our superior supply chain execution and innovative products and services Pharma U.S. / Canada Cardinal Health and Med Supply Post-Spin Specialty Distribution distribution >$90B FY09 pro Operating forma revenue* Nuclear/ Room related Specialty products/ Pharma services Medicine Pharmacy Shoppe Services** **Cardinal Health is continuing to Int’l** conduct an analysis of Pharmacy Services and Medicine Shoppe International to evaluate their future strategic fit. *An estimate of the pro forma revenue for fiscal 2009 in accordance with generally accepted accounting principles with adjustments expected to reflect each company as a stand-alone entity. The estimate is based on assumptions that management currently believes are reasonable, but actual revenue may vary materially from the estimate. 16
  • 17. The Business Case: Significant footprint and scale • 90% of U.S. hospitals use our products or services • More than 50,000 deliveries are made each day to 40,000 customer sites in U.S. • Leading distributor of U.S. prescriptions, medical/surgical and lab products through our system • Largest U.S. nuclear pharmacy provider, with more than 13 million prescriptions dispensed each year • Largest provider of products / services to acute care hospitals in North America 17
  • 18. Our value proposition • Large, deep and broad footprint across health channels – Retail, hospital, sub-acute, mail-order, ambulatory • Provide products / services that empower doctors, pharmacists and nurses to focus on what’s most important − patients • Our scale and breadth position us to help reduce costs, improve quality and outcomes, and satisfy needs across the healthcare system 18
  • 19. Growth drivers • Pressure on healthcare system to be more accessible, more productive, higher quality and safer • Demographics – aging population demands more health care products / services • Increasing use of generic pharmaceuticals • Opportunities to increase formulary-type Cardinal Health private label programs • Strong positioning in all retail channels • Highly efficient cost structure 19
  • 20. We provide valuable solutions throughout the pharma distribution channel Aligning offerings Suppliers Customers Generic Retail Independents Chains/ Hospital Branded Warehousing and • Market share • Pharmaceutical/ • Pharma • Inventory mgt distribution services distribution Non-warehousing • Launch speed • Data reporting • Pharmacy brands • Medication • Contract mgt • High service •Distribution / • Leader® brand packaging levels operational excellence • Efficient reach to • Rx purchasing • Fluid every COT • Contract mgt •Ordering / inventory programs management management • AR / returns mgt • AR / returns mgt products • FirstScript – customized •Purchasing solutions • Centralized • Special handling Autoshipment to stock • Infection shipping •SOURCE generics • Centralized new brand or generic prevention (primary and back-up • Data reporting shipping items fast (gloves, formulary) convertors) • Efficient reach • Front-end purchasing & •Home health care, to every COT merchandising • Surgical kitting packaging, FirstScript • Managed care • Consulting/ •Managed care programs design services • Ordering / inventory management 20
  • 21. For example… Improving reimbursements Creating alternate revenue streams Leader® improves reimbursements by taking Leader® creates alternate revenue streams the guesswork out of dealing with PBMs, such as home healthcare, durable medical providing reimbursement support, protecting equipment and diabetes management to margins and providing reassurances that each solidify an independent pharmacy as a claim is submitted and collected properly. community’s complete healthcare destination. Retail Independent Pharmacy “CEO” = Pharmacist Increasing marketshare Streamlining operations Leader® streamlines operations through Leader® increases market share and proactive inventory management and addressing establishes strong brand recognition by optimizing advertising strategies, workflow issues related to staffing shortages, high implementing effective store signage and labor costs, increasing scripts, decreasing margins providing a profitable private label line. and patient safety requirements. 21
  • 22. And we provide valuable solutions throughout the medical/surgical distribution channel • Leading position in acute care • Meaningful presence in lab setting • Focused on critical areas of hospital from quality and economic standpoint – Operating room – Presource®, convertors, fluid management, gloves – Cardiac imaging – nuclear pharmacy • Increasing position in ambulatory/alternate sites as care moves out of acute care setting 22
  • 23. For example… Logistics and replenishment Product Portfolio Valuelink – leading just-in-time inventory solution Broad portfolio of brand / proprietary products Optifreight – help customers manage freight costs Expanding private label line Custom solutions Hospital CEO/COO/Head of Purchasing Operational improvements Kitting Order-to-cash and SG&A Presource® - product offerings tailored to customer needs to improve supply chain management 23
  • 24. FY09 priorities and key initiatives Improve the quality and productivity of healthcare Invest and Sweeten our Innovate to Rebuild a execute mix (customer improve winning flawlessly to and product) customer culture build core loyalty by capabilities segment Enabled through information, insight and technology 24
  • 25. Near-term performance indicators • Increase direct-store-door sales • Resolve anti-diversion challenges • Increase proprietary generic Source program sales • Maintain U.S. medical distribution momentum and grow the private label 25
  • 27. SpinCo business portfolio Improving lives through better technology at the point of care SpinCo Respiratory and Infusion Neurocare Clinical and Medical Products Medical >$4B FY09 pro Specialties Dispensing forma revenue* (surgical products) Infection Clinical Prevention Services *An estimate of the pro forma revenue for the 12 months ended June 30, 2009 in accordance with generally accepted accounting principles with adjustments expected to reflect each company as a stand-alone entity. The estimate is based on assumptions that management currently believes are reasonable, but actual revenue may vary materially from the estimate. 27
  • 28. Quality and patient safety issues abound Annual Serious Adverse Events in • Hospital costs alone from adverse a Typical 300-Bed Hospital drug events are estimated at $3-6B – Excludes costs associated with patient injury and legal claims • Hospital infections add an estimated $30B to the nation’s hospital costs annually • Costs are largely borne by the providers, payers, and government CMP is uniquely focused on addressing the top 3 hospital Sources: Solucient, First Consulting Group, 2004 patient safety issues 28
  • 29. CMP is uniquely positioned to focus on key issues… Improve • Integrating our offers and knowledge to manage all medications medication • Uniquely positioned to improve safety and productivity management • Established role and presence in the surgical suite Enhance infection • Expansion into the large respiratory market prevention • Focus on protocol compliance and clinically differentiated products • Expanding our capability with high impact procedures Minimize risk and cost of procedures • Tackling our customers latest concerns Help hospitals • Leading market offering in infection detection identify patients at • Building our data to address top hospital concerns risk 29
  • 30. …with industry leading positions • Global leader in medication safety and infusion systems • Largest U.S. hospital footprint in dispensing systems • Largest acute-care respiratory company worldwide • Industry’s most comprehensive medication management solution • Leader in hospital-acquired infection (HAI) prevention • Leader in positive patient identification • Leader in U.S. surgical instrumentation 30
  • 31. In key product areas, critical to care… Infusion Ventilation Surgical Infection instruments Prevention Dispensing 31
  • 32. …such as dispensing, where we have a significant portion of the installed U.S. base • Significantly outperform competition Dispensing revenue – Revenue growth – Operating margin • Strong domestic demand – Committed contracts and strong backlog provide continuous momentum CAH – Consistent, high renewal rate • Next generation innovation and integrated offerings Competitor 1 Competitor 2 CAH Cardinal Health data analysis; data extrapolated from earnings releases. Renewal rates on 5-year leases are 95 – 99% 32
  • 33. And infusion, where we took >60% of business from competition in FY08 • Continued both premium pricing / gains in placements – 37% of U.S. installed base – 63% of U.S. placements • Strong international expansion – Expanded manufacturing capacity – Exceeding our expectation Disposable contracts create 5-year annuity stream for infusion pumps 33
  • 34. Combined with being world’s largest acute-care respiratory company • Industry leadership – Ventilation leader - 50% growth in VIASYS installed base in past 3 years – Leading cardiopulmonary testing platform • Leading innovator – Leading technology in ventilation (critical care & portable) and diagnostics (respiratory & sleep) – Innovative offerings that address ventilator-associated pneumonia – Over 200 active patents, 300 engineers and credentialed clinicians • Unique breadth – Capital equipment and disposables for adult, pediatric, neonatal, invasive, non-invasive, nCPAP, high-frequency – Continuum of offerings beyond hospital setting – VIASYS adds strong international channel 34
  • 35. And a strong player in infection prevention, with next-generation products • Innovation – Leading-edge infection prevention continuum in development • Revenue expansion – Expanding demand for infection detection and prevention – Enturia acquisition – International penetration • Margin expansion – Mix-shift in base products – Operational Excellence/Lean – Flexible manufacturing/sourcing model 35
  • 36. CMP (SpinCo) key near- to mid-term priorities 1 Drive innovation and clinical differentiation – R&D pipeline is loaded − expecting to launch ~45-50 new products and enhanced solutions over the next 18 months 2 Use industry leading positions to accelerate growth – Grow international sales by expanding country specific strengths 3 Successfully complete integrations (VIASYS and Enturia) – Cost and revenue synergies – Respiratory business model transformation Continue rounding out our solutions 4 – Expand organically through product and solution innovation – Strategic tuck-ins 36
  • 38. Total company FY 2009 priorities • Achieve FY09 operational and financial objectives • Resolve outstanding regulatory issues • Enhanced investment in R&D and IT • Return HSCS to steady growth • Successfully complete integrations (VIASYS, Enturia, Borschow) • Efficiently execute a spin-off of the CMP businesses, while minimizing disruption 38
  • 39. FY09 financial goals August 7, 2008 Total revenue growth: 6-7% Non-GAAP EPS1: $3.80 - $3.95 Revenue Profit Segment Growth Growth Healthcare Supply Chain Services (HSCS) >6% Flat to (5%) Clinical and Medical Products (CMP) >10% >20% 1 Non-GAAP diluted earnings per share from continuing operations 39
  • 40. FY09 assumptions update • Capital deployment – Share repurchases to no more than offset equity compensation issuances – Continue regular $0.14 quarterly dividend until spin-off is completed • Portfolio rationalization/review – MedSystems sale closed 8/29/08 – Tecomet sale closed 9/26/08 – Review of MSI and Pharmacy Services ongoing • Special items and/or other expenses / charges related to spin-off not included in guidance – Anticipate a significant portion of costs related to spin-off may be classified as special items in accordance with company practices 40
  • 41. Summary: So why invest in current Cardinal Health now? Two industry-leading businesses … With talented, experienced management … Well-positioned to drive future growth … With a focus on and commitment to ... Delivering value to shareholders. 41
  • 42. Q&A