organic chemistry, polymers

1. By/ Huda Eid AbdelWahab

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•Origin and sources
• Physico-chemical properties
• Applications and uses

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Crustacean shells, insect exoskeleton
and some fungi =
mainly chitin.

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Chitin
Chitosan
Deacetylation
(boiling 40-50%
NaOH)

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β(1 4) linked D-glucose units
β(1 4) linked N-acetyl-D-glucos-
2-amine units
β(1 4) linked D-glucos-2-amine
units
Degree of DeAcetylation > 60%

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7. -OH: esterification, etherification,
oxidation,Elimination, protection reactions
-NH2: amidation, reduction, mono-, di- and
trialkylation (electrophile subsitution),
protection reactions
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8. Complexation ability
• metal ions
• anionic polymers
• amino acids, proteins, DNA, cells
• dyes
• fats and cholesterol
8

9. SYNTHESIS OF SOME TEREPHTHALOYL THIOUREA
CROSS-LINKED CARBOXYMETHYL CHITOSAN HYDROGELS
9

10. SYNTHESIS OF SILICA-CHITOSAN HYBRIDS FOR
ANTIWETTING COATINGS
10

11. DEVELOPING A CHITOSAN SUPPORTED IMIDAZOLE
SCHIFF-BASE FOR HIGH-EFFICIENCY GENE DELIVERY
11

12. Characterization of a Conjugate between
Rose Bengal and Chitosan for Targeted
Antibiofilm and Tissue Stabilization
Effects as a Potential Treatment of
Infected Dentin
12

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14. N-Phthaloylated Chitosan as
an
Essential Precursor for
Controlled
Chemical Modifications of
Chitosan
14

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16. Synthesis And Characterization Of Chitosan Bi guanidine
Hydrochloride Under Microwave Irradiation
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17. Carboxymethyl chitosan and
its
applications
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22. SYNTHESIS ROUTE TO THE CHITOSAN DERIVATIVES OF
OCTADECYL-QUATERNIZED CARBOXYMETHYL CHITOSAN
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23. SYNTHESIS OF PALMITOYL GLYCOL CHITOSAN
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1-Water treatment
2-Paper
Removal of metal ions
Flocculant/coagulant (proteins, dyes,
aminoacids)
Filtration
Surface treatment
Photographic paper
Carbonless copy paper
Application
Examples

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3-Medical
4- Cosmetics
Bandages, sponges
Artificial blood vessels
Blood cholesterol control
Tumor inhibition
Skin burns, artificial skin
Eye humor fluid
Contact lenses
Controlled release of drugs
Nanoparticles for drug delivery
Make-up powder
Nail polish
Mosturizers

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5- Biotechnology
6- Agriculture
Enzyme/cell immobilization
Protein separation
Chromatography
Glucose electrode
Seed/leaf coating
Fertilizer
Controlled agrochemical
release

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7- Food Removal of dyes and acids
Preservative
Color stabilization
Animal feed additive
As dietary food
Main properties used: antimicrobial ,
film forming, binding
capacity.