Oral films will give u good release of drug & relief from acute pain & problems...

1. FAST DISSOLVING ORAL FILMS
PRESENTED BY
B.JAGADEESH BABU
M.Pharm

2. OVER VIEW
INTRODUCTION
SPECIAL FEATURES
GENERAL PROPERTIES
FORMULATION
METHOD OF PREPARATION
EVALUATION TESTS
ADVANTAGES & DISADVANTAGES
CONCLUSION

3. INTRODUCTION
 These are the drug delivery systems
which fastly disintegrate in mouth with
H2O.
 It was first developed in 1970’s
alternative to tablets & capsules.
 It consists of very thin oral strip which is
placed on tongue & upon hydration it
fastly releases drug into oral cavity.

4.  Thin elegant film
 Available in various sizes & shapes
 Unobstrusive
 Excellent mucoadhesion
 Rapid release

5. GENERAL PROPERTIES
 Thickness ranges from 1-10mm & it’s surface area is
1-20 cm².
 Its low dry tack allows for ease of handling &
application.
 Its rapid hydration rate facilitates fast softening &
absorption.
 2mm thickness of film will take 5-10sec to start its
disintegration.

7. FORMULATION
 DRUG
 WATER SOLUBLE POLYMER
 SUPER DISINTEGRANTS
 PLASTISIZER
 SURFACTANTS
 FLAVOURS
 COLOURS
 SWEETENING AGENTS
 SALIVA STIMIULATING AGENTS

8.  SOLVENT CASTING*
 SEMI-SOLID CASTING
 HOT MELT EXTRUSION
 SOLID DISPERSION EXTRUSION
 ROLLING METHOD

9. EVALUATION TESTS
 MORPHOLOGY STUDY
 SWELLING PROPERTY
 CONTACT ANGLE
 DISINTEGRATION
 MECHANICAL PROPERTIES
1. Tensile strength
2.Elastic modulus
3.% Elongation
4. Folding endurance

10.  Convenient dosing
 No water needed
 No risk of chocking
 Taste masking
 Enhanced stability
 First pass metabolism can be avoided

11.  Easily fragile & brittle.
 Special package for protection during storage &
transportation.

12.  These are having several advantages
over conventional dosage forms like
ODT, TABLETS, CAPSULES ,IV etc., so
they are of great importance during the
emergency cases such as allergic
reations & asthamatic attacks.