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T C ’ S P O T P O U R R I
T H E M E M E E D I T I O N
W H A T I S A M E M E ?
F E A S T S T U D Y
• I’ve mentioned it before
• Essentially found shocked
septic kids in Africa did worse
with fluid boluses over
maintenance fluid
• Comment from the floor was
“yeah but they’ll all have
malaria and the fluid will make
their cerebral oedema worse”
• Fair enough
S H U T U P F E R G I E
• The non-anaemic and non-malaria patients were
analysed
• Found to have the same poor outcomes with fluid
boluses over maintenance fluids as the anaemia and
malaria kids
• Regardless of whether albumin or crystalloids given
S G A R B O S S A C R I T E R I A
• Smith modified Sgarbossa rule:
• At least one lead with concordant STE (Sgarbossa criterion
1) or
• At least one lead of V1-V3 with concordant ST depression
(Sgarbossa criterion 2) or
• Proportionally excessively discordant ST elevation in V1-V4,
as defined by an ST/S ratio of equal to or more than 0.20
and at least 2 mm of STE. (this replaces Sgarbossa criterion
3 which uses an absolute of 5mm)
S E V E R E C U T A N E O U S A D V E R S E
R E A C T I O N S
• Drug hypersensitivity syndrome is the same as DRESS
• SJS/TEN
• Acute generalised exanthematous pustulosis (AGEP)
• drug induced erythroderma
• Severe, unexpected reaction to a medicine(s)
• high fever, a morbilliform skin rash
• inflammation of one or more internal organs including the liver, kidneys, lungs
and/or heart
• It generally starts two to eight weeks after taking the responsible medicine.
C U L P R I T S
• Allopurinol
• AEDs esp. carbamazepine, phenobarbitol, phenytoin
• Sulfonamides
• But really anything
M E A C U L P A
wire
left in
Individual
Factors
Patient
Factors
Task
Factors
Education
and
Training
Team and
Social
Factors
Working
Conditions
Equipment
and
resources
Communi
cation
Organisati
onal and
strategic
Factors
C H O I C E S R A N K R A T E
1 8 G I V C 8 . 5 F R R I C 0 0 : 4 6
6 F R S H E A T H 7 F R R I C 1 : 0 0
8 . 5 F R R I C 8 . 5 F R S H E A T H 1 : 0 5
1 4 G L U M E N C V C 1 4 G I V C 1 : 3 0
7 F R R I C 6 F R S H E A T H 2 : 1 0
1 6 G I V C 1 4 G 1 3 . 3 C M I V C 2 : 1 0
2 0 G I V C 1 6 G I V C 2 : 2 0
1 4 G I V C 1 8 G I V C 4 : 2 3
8 . 5 F R S H E A T H 1 4 G L U M E N C V C 5 : 2 0
1 4 G 1 3 . 3 C M I V C 2 0 G I V C 6 : 4 7
C O U N T R Y W E E K
• 13yo playing football, someone stepped on his foot
while trying to spin round
• pain
T I L L A U X F R A C T U R E
• Salter Harris III distal tibia epiphysis
• Caused by an avulsion of the anterior inferior tibiofibular ligament
• Mechanism of injury is thought to be due to an external rotation force
• 12-14yo
• A period of time exists when the lateral physis is the only portion not
fused
• An additional fracture in the posterior distal tibial metaphysis in the
coronal plane would result in a…?
B A R B A R A
• 70yo lady
• sore right knee
• normal XR with GP
• moderate effusion, ROM ~70º
• No PMHx
P L A N ?
W H A T A R E Y O U L O O K I N G
F O R I N T H E S Y N O V I A L
F L U I D ?
C O U R S E
• D/C with NSAIDS and Dx with pseudogout
• Recalled 2 days later after bacteria grown
• Sent home by ED as patient feeling ok
• No bloods done
• Back 5 days after initial presentation with obvious
septic joint
• Unwitnessed arrest
• Initial non-VF Rhythm
• Lack of bystander CPR
• >30 min to ROSC
• >30 min of CPR
• Evidence of unresponsive hypoperfusion and microcirculatory failure:
• pH <7.2 and Lactate >7
• Age >85
• End-Stage Renal Disease (ESRD
• Non-Cardiac Causes: Cardiac arrest due to drugs, drowning, acute stroke, terminal cancer and trauma,
just to name a few non-cardiac causes, are likely to result in poor outcomes post-resuscitation.
Unfavourable for Cath
A V O I D
• All STEMI criteria patients
• excluded if sats <94%
• There was an increase in the rate of recurrent myocardial infarction in
the oxygen group compared with the no oxygen group (5.5% versus
0.9%; P=0.006)
• An increase in frequency of cardiac arrhythmia (40.4% versus 31.4%;
P=0.05).
• At 6 months, the oxygen group had an increase in myocardial infarct
size on cardiac magnetic resonance (n=139; 20.3 versus 13.1 g;
P=0.04).
P L U G F O R A C H A R I T Y
• I’ve belonged for ~5years
• “Medics Beyond Medicine”
• For doctors who want to connect with people with
mental and physical disabilities rather than just see
them in a clinical setting
• Generally revolves around outings
• Recently featured on channel 9 news
• Emma and Dave volunteered their time
• “Daniel” here has myotonic dystrophy as seen by the
tell tale baldness pattern
• “Chris” has a rare chromosomal abnormality that
means he has a compulsion to wear a cap in an
inappropriate setting
A G E A D J U S T E D D - D I M E R
• Wells score ≤4
• Age ✷ D-dimer (0.01mg/L)
• ie a 70yo will have an acceptable D-dimer <0.7mg/L
• Validated in multiple studies
• I think we should use it
C E N T O R
• History of fever
• Tonsillar exudates
• Tender anterior cervical adenopathy
• Absence of cough
• The Modified Centor Criteria add the patient's age to the criteria
• Age <15 add 1 point
• Age >44 subtract 1 point
• -1, 0 or 1 points - No antibiotic or throat culture necessary (Risk
of strep. infection <10%)
• 2 or 3 points - Should receive a throat culture and treat with an
antibiotic if culture is positive (Risk of strep. infection 32% if 3
criteria, 15% if 2)
• 4 or 5 points - Treat empirically with an antibiotic (Risk of strep.
infection 56%)
• The presence of all four variables indicates a 40 - 60% positive
predictive value for a culture of the throat to test positive for
Group A Streptococcus bacteria. The absence of all four
variables indicates a negative predictive value of greater than
80%
W H A T A N T I B I O T I C
• Phenoxymethylpenicllin
• Cheap, proven
• Never been a resistant GABHS to penicillin
• Good anaerobic cover just in case the patient has…
F U S O B A C T E R I U M
N E C R O P H O N U M
• lemierre’s syndrome
• Thrombus of the internal jugular
• Sepsis
• Mortality of ~5%
• Not sensitive to macrolides
TC's emergency medicine wrap up 4

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TC's emergency medicine wrap up 4

  • 1. T C ’ S P O T P O U R R I T H E M E M E E D I T I O N
  • 2. W H A T I S A M E M E ?
  • 3. F E A S T S T U D Y • I’ve mentioned it before • Essentially found shocked septic kids in Africa did worse with fluid boluses over maintenance fluid • Comment from the floor was “yeah but they’ll all have malaria and the fluid will make their cerebral oedema worse” • Fair enough
  • 4. S H U T U P F E R G I E • The non-anaemic and non-malaria patients were analysed • Found to have the same poor outcomes with fluid boluses over maintenance fluids as the anaemia and malaria kids • Regardless of whether albumin or crystalloids given
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  • 7. S G A R B O S S A C R I T E R I A • Smith modified Sgarbossa rule: • At least one lead with concordant STE (Sgarbossa criterion 1) or • At least one lead of V1-V3 with concordant ST depression (Sgarbossa criterion 2) or • Proportionally excessively discordant ST elevation in V1-V4, as defined by an ST/S ratio of equal to or more than 0.20 and at least 2 mm of STE. (this replaces Sgarbossa criterion 3 which uses an absolute of 5mm)
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  • 9. S E V E R E C U T A N E O U S A D V E R S E R E A C T I O N S • Drug hypersensitivity syndrome is the same as DRESS • SJS/TEN • Acute generalised exanthematous pustulosis (AGEP) • drug induced erythroderma • Severe, unexpected reaction to a medicine(s) • high fever, a morbilliform skin rash • inflammation of one or more internal organs including the liver, kidneys, lungs and/or heart • It generally starts two to eight weeks after taking the responsible medicine.
  • 10. C U L P R I T S • Allopurinol • AEDs esp. carbamazepine, phenobarbitol, phenytoin • Sulfonamides • But really anything
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  • 12. M E A C U L P A
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  • 19. C H O I C E S R A N K R A T E 1 8 G I V C 8 . 5 F R R I C 0 0 : 4 6 6 F R S H E A T H 7 F R R I C 1 : 0 0 8 . 5 F R R I C 8 . 5 F R S H E A T H 1 : 0 5 1 4 G L U M E N C V C 1 4 G I V C 1 : 3 0 7 F R R I C 6 F R S H E A T H 2 : 1 0 1 6 G I V C 1 4 G 1 3 . 3 C M I V C 2 : 1 0 2 0 G I V C 1 6 G I V C 2 : 2 0 1 4 G I V C 1 8 G I V C 4 : 2 3 8 . 5 F R S H E A T H 1 4 G L U M E N C V C 5 : 2 0 1 4 G 1 3 . 3 C M I V C 2 0 G I V C 6 : 4 7
  • 20. C O U N T R Y W E E K • 13yo playing football, someone stepped on his foot while trying to spin round • pain
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  • 22. T I L L A U X F R A C T U R E • Salter Harris III distal tibia epiphysis • Caused by an avulsion of the anterior inferior tibiofibular ligament • Mechanism of injury is thought to be due to an external rotation force • 12-14yo • A period of time exists when the lateral physis is the only portion not fused • An additional fracture in the posterior distal tibial metaphysis in the coronal plane would result in a…?
  • 23.
  • 24. B A R B A R A • 70yo lady • sore right knee • normal XR with GP • moderate effusion, ROM ~70º • No PMHx
  • 25. P L A N ?
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  • 27. W H A T A R E Y O U L O O K I N G F O R I N T H E S Y N O V I A L F L U I D ?
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  • 31. C O U R S E • D/C with NSAIDS and Dx with pseudogout • Recalled 2 days later after bacteria grown • Sent home by ED as patient feeling ok • No bloods done • Back 5 days after initial presentation with obvious septic joint
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  • 34. • Unwitnessed arrest • Initial non-VF Rhythm • Lack of bystander CPR • >30 min to ROSC • >30 min of CPR • Evidence of unresponsive hypoperfusion and microcirculatory failure: • pH <7.2 and Lactate >7 • Age >85 • End-Stage Renal Disease (ESRD • Non-Cardiac Causes: Cardiac arrest due to drugs, drowning, acute stroke, terminal cancer and trauma, just to name a few non-cardiac causes, are likely to result in poor outcomes post-resuscitation. Unfavourable for Cath
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  • 37. A V O I D • All STEMI criteria patients • excluded if sats <94% • There was an increase in the rate of recurrent myocardial infarction in the oxygen group compared with the no oxygen group (5.5% versus 0.9%; P=0.006) • An increase in frequency of cardiac arrhythmia (40.4% versus 31.4%; P=0.05). • At 6 months, the oxygen group had an increase in myocardial infarct size on cardiac magnetic resonance (n=139; 20.3 versus 13.1 g; P=0.04).
  • 38.
  • 39. P L U G F O R A C H A R I T Y • I’ve belonged for ~5years • “Medics Beyond Medicine” • For doctors who want to connect with people with mental and physical disabilities rather than just see them in a clinical setting • Generally revolves around outings • Recently featured on channel 9 news
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  • 42. • Emma and Dave volunteered their time • “Daniel” here has myotonic dystrophy as seen by the tell tale baldness pattern • “Chris” has a rare chromosomal abnormality that means he has a compulsion to wear a cap in an inappropriate setting
  • 43. A G E A D J U S T E D D - D I M E R • Wells score ≤4 • Age ✷ D-dimer (0.01mg/L) • ie a 70yo will have an acceptable D-dimer <0.7mg/L • Validated in multiple studies • I think we should use it
  • 44. C E N T O R • History of fever • Tonsillar exudates • Tender anterior cervical adenopathy • Absence of cough • The Modified Centor Criteria add the patient's age to the criteria • Age <15 add 1 point • Age >44 subtract 1 point • -1, 0 or 1 points - No antibiotic or throat culture necessary (Risk of strep. infection <10%) • 2 or 3 points - Should receive a throat culture and treat with an antibiotic if culture is positive (Risk of strep. infection 32% if 3 criteria, 15% if 2) • 4 or 5 points - Treat empirically with an antibiotic (Risk of strep. infection 56%) • The presence of all four variables indicates a 40 - 60% positive predictive value for a culture of the throat to test positive for Group A Streptococcus bacteria. The absence of all four variables indicates a negative predictive value of greater than 80%
  • 45. W H A T A N T I B I O T I C • Phenoxymethylpenicllin • Cheap, proven • Never been a resistant GABHS to penicillin • Good anaerobic cover just in case the patient has…
  • 46.
  • 47. F U S O B A C T E R I U M N E C R O P H O N U M • lemierre’s syndrome • Thrombus of the internal jugular • Sepsis • Mortality of ~5% • Not sensitive to macrolides