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Coronary Heart Disease and Exercise: What’s the evidence? Yeong Yeh Lee MD MRCP(UK) MMed May 2009
Basics
Exercise & the Heart ,[object Object],[object Object],[object Object],[object Object],[object Object]
HR response to exercise ,[object Object],[object Object],[object Object]
Distribution of CO during Exercise ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Distribution of CO during Exercise termination ,[object Object],[object Object],[object Object],[object Object]
CV response to different type of exercises ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical
Coronary Heart Disease ,[object Object],[object Object],[object Object]
Risk Factors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rx ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rx ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rx ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Trials
CHD & Exercise ,[object Object],[object Object],[object Object],[object Object]
CHD & Exercise ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CHD & Exercise ,[object Object],[object Object],[object Object]
CHD & Exercise ,[object Object],[object Object],[object Object]
CHD & Exercise -benefits ,[object Object],[object Object],[object Object],[object Object]
CHD & Exercise – Additional benefits ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CHD & Exercise – Additional benefits ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PRIMARY  PREVENTION
PRIMARY PREVENTION ,[object Object],[object Object]
Harvard alumni health study Paffenberger et al. NEJM 1993; 328:538. Sesso et al Circ 2000; 102:975. Lee et al Circ 2000; 102:981   ,[object Object],[object Object],[object Object],[object Object]
Changes in physical fitness and all-cause mortality. A prospective study of healthy and    unhealthy men .   Blair JAMA 1995; 273:1093. ,[object Object],[object Object],[object Object]
Finnish Twin Cohort study  Kujala et al. JAMA 1998; 279:440   ,[object Object],[object Object]
Nurses' Health study Manson JE at al NEJM 1999; 341:650.   Lee IM et al JAMA 2001; 285:1447  ,[object Object],[object Object],[object Object],[object Object]
American Heart Association (AHA) Circulation 1997; 96:355  ,[object Object],[object Object]
SECONDARY PREVENTION
SECONDARY PREVENTION – ,[object Object],[object Object],[object Object],[object Object]
Meta analysis Oldridge  et al. Cardiac rehabilitation after myocardial infarction.  Combined experience of randomized clinical trials. JAMA 1988; 260:945. ,[object Object],[object Object],[object Object]
National Exercise and Heart Disease Project   Circulation 1999; 100:1764 Am J Cardiol 1981; 48:39  ,[object Object],[object Object],[object Object],[object Object]
American Heart Association (AHA) ,[object Object],[object Object]
 
THE EXERCISE PRESCRIPTION Practical recommendations for exercise programs and for classification of exercise risk, which determine the need for supervision and monitoring, have recently been published
 
Primary Prevention ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Primary Prevention ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Secondary prevention ,[object Object]
Secondary prevention   ,[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusion ,[object Object],[object Object]

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