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THE CYCLE CELL AND
 STRUCTURE DNA



           Laura Elena Cuartas
           Molecular Biology
           July 22/2012
           UPB- Medellín
Telomeres           and
telomerase serve to give
information about   age
and pathologies      like
cancer.




Cell division is a important
process to give rise to new
   cells containing their
    complete genomas.
Using    biochemical       and
genetic assays the protein
Lem4 is structurally different
in human cells and embryos
of the worm, but have the
same function in cell division.
Lem4 is a protein which
simultaneously   co-ordinates
the activity of kinases and
phosphatases on a target
protein essential for cell
division.
It is essential that the nuclear envelope disappears
during cell division and then reassemble it correctly, to
occur this is necessary for the participation of kinases
and phosphatases proteins.
Lem4 protein has a relation with the cancer
                 patients
In this study we can observe the importance of
phosphorylation and desphosphorylation reactions
and its essential role in cell division and cell
operation.
Telomerases      protect
chromosomes         from
deteriorating and guard
the genetic information
at     the    ends     of
chromosomes       during
cell division. Besides’
they are      considered
markers of biological or
cellular          aging.
Shortened telomeres have been linked to increased risk
of cancers, heart disease, dementia and mortality.
The     length     of
telomeres depends
on    the     stress,
worries          and
phobias.
I think anxienty and stress are emotional
feeling that people can control, because
these affect cromosomes in the telomeres
and reduce life average.
The DNA structure is very important because it
has the information about each personal
genome, this study has to protect the life and the
personal safety and the culture of the people
because al cientific investigation has to be ethics.
Knowledge of the
nuclear    envelope
met know different
molecules involved
in cell cycle and
that way related
pathologies such as
cancer.
• MARTINEZ SANCHÉZ. LINA MARÍA. BIOLOGÍA MOLECULAR. 7.
  ED. MEDELLÍN: UPB. FAC. DE MEDICINA, 2012. 44-51 PAG.

• Asencio C. Identified a essential protein in nuclear envelope
  assembly in cell division, according to the UPO.Europapresst
  [Internet journal] 2012 Jul [access 20 of July of 2012].
  Available:        http://www.europapress.es/andalucia/sevilla-
  00357/noticia-identifican-proteina-esencial-ensamblaje-
  envoltura-nuclear-division-celular-upo-20120713150648.html

• Okereke O. Anxiety linked to shortened telomeres,
  accelerated aging: research. Medicalxpress [Internet journal]
  2012 Jul [access 20 of July of 2012]. Available:
  http://medicalxpress.com/news/2012-07-anxiety-linked-
  shortened-telomeres-aging.html
Biologia molecular

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Biologia molecular

  • 1. THE CYCLE CELL AND STRUCTURE DNA Laura Elena Cuartas Molecular Biology July 22/2012 UPB- Medellín
  • 2.
  • 3.
  • 4. Telomeres and telomerase serve to give information about age and pathologies like cancer. Cell division is a important process to give rise to new cells containing their complete genomas.
  • 5.
  • 6. Using biochemical and genetic assays the protein Lem4 is structurally different in human cells and embryos of the worm, but have the same function in cell division.
  • 7. Lem4 is a protein which simultaneously co-ordinates the activity of kinases and phosphatases on a target protein essential for cell division.
  • 8. It is essential that the nuclear envelope disappears during cell division and then reassemble it correctly, to occur this is necessary for the participation of kinases and phosphatases proteins.
  • 9. Lem4 protein has a relation with the cancer patients
  • 10. In this study we can observe the importance of phosphorylation and desphosphorylation reactions and its essential role in cell division and cell operation.
  • 11.
  • 12. Telomerases protect chromosomes from deteriorating and guard the genetic information at the ends of chromosomes during cell division. Besides’ they are considered markers of biological or cellular aging.
  • 13. Shortened telomeres have been linked to increased risk of cancers, heart disease, dementia and mortality.
  • 14. The length of telomeres depends on the stress, worries and phobias.
  • 15. I think anxienty and stress are emotional feeling that people can control, because these affect cromosomes in the telomeres and reduce life average.
  • 16.
  • 17. The DNA structure is very important because it has the information about each personal genome, this study has to protect the life and the personal safety and the culture of the people because al cientific investigation has to be ethics.
  • 18. Knowledge of the nuclear envelope met know different molecules involved in cell cycle and that way related pathologies such as cancer.
  • 19. • MARTINEZ SANCHÉZ. LINA MARÍA. BIOLOGÍA MOLECULAR. 7. ED. MEDELLÍN: UPB. FAC. DE MEDICINA, 2012. 44-51 PAG. • Asencio C. Identified a essential protein in nuclear envelope assembly in cell division, according to the UPO.Europapresst [Internet journal] 2012 Jul [access 20 of July of 2012]. Available: http://www.europapress.es/andalucia/sevilla- 00357/noticia-identifican-proteina-esencial-ensamblaje- envoltura-nuclear-division-celular-upo-20120713150648.html • Okereke O. Anxiety linked to shortened telomeres, accelerated aging: research. Medicalxpress [Internet journal] 2012 Jul [access 20 of July of 2012]. Available: http://medicalxpress.com/news/2012-07-anxiety-linked- shortened-telomeres-aging.html