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A Research-based Model for
Interdisciplinary Training of STEM
         Undergraduates
             Jason Miller, Ph.D.
         Department of Mathematics
          Truman State University

              Missouri State University
                Chemistry Seminar
                 17 October 2012
                                          MSU Chem Seminar
                                           17 October 2012
MSU Chem Seminar
 17 October 2012
Outline
• Introduce Truman State University
• Story of Truman’s research-focused
  mathematical biology program
• Truman’s interdisciplinary STEM efforts
  degree
• Opportunities for Collaboration

                                            MSU Chem Seminar
                                             17 October 2012
Truman




Truman is in rural Kirskville, Missouri
                                          MSU Chem Seminar
                                           17 October 2012
Truman
         MSU Chem Seminar
          17 October 2012
About Truman
• Missouri’s only “highly selective” public
  liberal arts University; pride in high-quality
  teaching, small class size
• ~6000 undergraduates, ~300 faculty, 150
  Masters students
• Institutional commitment to Undergraduate
  Research and to Interdisciplinary teaching
    •   EX: all students must take a Junior
        Interdisciplinary Seminar

                                               MSU Chem Seminar
                                                17 October 2012
About Truman
• about 25 biology faculty, 35 mathematics
  faculty (math+stats+CS)
• biology: research expected of faculty (with
  students); experienced mentors
• mathematics: teaching focus, little or no
  support for research activity; 10 new faculty
  between 1998-2000


                                              MSU Chem Seminar
                                               17 October 2012
MSU Chem Seminar
 17 October 2012
Professional Societies




                     MSU Chem Seminar
                      17 October 2012
2003
       MSU Chem Seminar
        17 October 2012
2007
       MSU Chem Seminar
        17 October 2012
R E P OR T T O T H E PR E SI DEN T
ENGAGE TO E XCEL: PRODUCI NG ONE M ILLION
  A DDI T IONA L COLLEGE GR A DUAT ES W I T H
     DEGR EES I N SCIENCE , T ECH NOLOGY,
      ENGI NEER I NG, A N D M AT HEM AT ICS




         Executive Office of the President
          President’s Council of Advisors
            on Science and Technology


                F E BRUA RY 2 01 2




                                                MSU Chem Seminar
                                                 17 October 2012
MSU Chem Seminar
 17 October 2012
Mathematical Biology
   Seminar (since 2003)
• Program fulcrum
• Biweekly meeting of faculty and
  undergraduates
• Initially, a “Biology Fashion Show”
• Engineered several cross-disciplinary,
  research hook-ups
• Pairings provided us with a foundation for
  NSF UBM grant proposals
                                           MSU Chem Seminar
                                            17 October 2012
MSU Chem Seminar
 17 October 2012
Mathematical
               Life Scientist
  Scientist
                  (faculty)
  (faculty)




Mathematical
               Life Scientist
  Scientist
                 (trainee)
 (trainee)


                                MSU Chem Seminar
                                 17 October 2012
Mathematical
               Life Scientist
  Scientist
                  (faculty)
  (faculty)




Mathematical
               Life Scientist
  Scientist
                 (trainee)
 (trainee)


                                MSU Chem Seminar
                                 17 October 2012
MSU Chem Seminar
 17 October 2012
Mathematical                    Mathematical
               Life Scientist                  Life Scientist
  Scientist                       Scientist
                  (faculty)                       (faculty)
  (faculty)                       (faculty)



Mathematical                    Mathematical
               Life Scientist                  Life Scientist
  Scientist                       Scientist
                 (trainee)                       (trainee)
 (trainee)                       (trainee)




Mathematical                    Mathematical
               Life Scientist                  Life Scientist
  Scientist                       Scientist
                  (faculty)                       (faculty)
  (faculty)                       (faculty)



Mathematical                    Mathematical
               Life Scientist                  Life Scientist
  Scientist                       Scientist
                 (trainee)                       (trainee)
 (trainee)                       (trainee)

                                                                MSU Chem Seminar
                                                                 17 October 2012
• selection occurs in the Fall, students start
  work in January (year-long)

• weekly meetings during the academic year
• Intense 10-week summer research program


                                             MSU Chem Seminar
                                              17 October 2012
Summer



                  Residence Hall
                      Meals
         Small Group Meetings + Mentors
                   Community
          Weekly Discussions/Workshops
                  Social Events
                MathBio Seminar



                                          MSU Chem Seminar
                                           17 October 2012
Automatic Annotation of Maize Genome




      Collaboration between Truman, IA State,
           Cornell, Cold Spring Harbor.         MSU Chem Seminar
                                                 17 October 2012
Automatic Annotation of Maize Genome




     Collaboration between Truman, IA State,
          Cornell, Cold Spring Harbor.         MSU Chem Seminar
                                                17 October 2012
Geometric Modeling of C.elegan’s 4-cell stage




                                     MSU Chem Seminar
                                      17 October 2012
Graph Theoretic Modeling of Vascular
            Networks




   Collaboration between Truman and AT Still
         University of Health Sciences.        MSU Chem Seminar
                                                17 October 2012
Modeling Dispersion of Extinct Saccate Pollen




         Collaboration between Truman and the
                College of New Jersey.          MSU Chem Seminar
                                                 17 October 2012
Identifying Volant Bats via Echolocation




                       with Lynn Robbins, MSU Biology
                                           MSU Chem Seminar
                                            17 October 2012
Habitat Suitability modeling for the Missouri
                  Bladderpod




      Collaboration between Truman and the US
              Fish and Wildlife Service.        MSU Chem Seminar
                                                 17 October 2012
Statistical Modeling of Abundance of Beetle
                Populations




                                      MSU Chem Seminar
                                       17 October 2012
Models of Tick Respiration and Physiology




                                     MSU Chem Seminar
                                      17 October 2012
• A modified Tajima-D statistic for identifying
  causes of HIV mutation

• Modeling host-parasite interaction in a long-
  term site study

• Geometric modeling of gravitropic
  sensitivity in flax roots



                                            MSU Chem Seminar
                                             17 October 2012
Sustainability
• an expensive program ($25k per team)
• low throughput
• high impact
• wanted to pursue tactics for long-term
  sustainability




                                           MSU Chem Seminar
                                            17 October 2012
Core Courses
• Bioinformatics
• Introduction to Mathematical Biology
• Biostatistics/Biometry
• Introduction to Computational Science*
• Calculus & Math Methods for the Life
  Sciences


                                           MSU Chem Seminar
                                            17 October 2012
Interdisciplinary Minor
• Designed to foster thoughtful integration of
  skills and knowledge in mathematics and
  biology
• outcome based (electronic portfolio), not
  course/credit based
• for majors in biology, mathematics, computer
  science, agricultural science


                                            MSU Chem Seminar
                                             17 October 2012
Minor’s Outcomes
   • Data Acquisition
   • Modeling
   • Computation
   • Statistics
   • Research


                        MSU Chem Seminar
                         17 October 2012
Requirements
• Demonstrate proficiencies in each category
  (though research, courses)
• Earn 15+ credits doing so (must take Intro to
  MathBio course)
• Attend MathBio Seminar
• Participate in two half-semester program
  workshops/seminars

                                             MSU Chem Seminar
                                              17 October 2012
Other Courses
 • Any that makes a connection between the
    areas. Some example:
   • Math Modeling
   • Ecology                 • Developmental
                               Biology
   • ODEs
   • Genetics of             • (Electron)
                               Microscopy
       Animal and Plant
       Improvement
Each student makes a case for each course in their
learning plan.                                 MSU Chem Seminar
                                                17 October 2012
Accomplishments:
  Strong summer research community.
  Quality new courses: Bioinformatics, Intro to
  MathBio, Biostatistics, Intro to Computational
  Science, Calculus & Math Methods for Life Science
  Competency-based minor in mathematical biology.
  Faculty embrace interdisciplinary approaches to
  research.




                                              MSU Chem Seminar
                                               17 October 2012
MathBio Notes
• Program grew from institutional strengths
  and interests, meeting the needs of many

• Creates a learning-centered community for
  faculty and students

• Trains students through research; discomfort
  is a sign of success



                                             MSU Chem Seminar
                                              17 October 2012
• Our program was the perfect means for
  developing infrastructure and faculty buy-in

• It is an imperfect model for a sustainable
  quantitative or mathematical biology
  program

• (But it puts us in a very powerful position as
  Truman launches it next efforts.)


                                               MSU Chem Seminar
                                                17 October 2012
More details: Miller, Walston. Interdisciplinary Training in
Mathematical Biology Through Team-based Undergraduate
Research and Courses. CBE Life Sci Educ. 2010 Fall;9(3):284-9.




                                                     MSU Chem Seminar
                                                      17 October 2012
STEM Talent Expansion
Programs (STEP) Office



                        MSU Chem Seminar
                         17 October 2012
2003
       MSU Chem Seminar
        17 October 2012
2007
       MSU Chem Seminar
        17 October 2012
R E P OR T T O T H E PR E SI DEN T
ENGAGE TO E XCEL: PRODUCI NG ONE M ILLION
  A DDI T IONA L COLLEGE GR A DUAT ES W I T H
     DEGR EES I N SCIENCE , T ECH NOLOGY,
      ENGI NEER I NG, A N D M AT HEM AT ICS




         Executive Office of the President
          President’s Council of Advisors
            on Science and Technology


                F E BRUA RY 2 01 2




                                                MSU Chem Seminar
                                                 17 October 2012
STEM Talent Expansion
• Truman has leveraged training through
  undergraduate research for other programs

  • NSF STEP
  • NSF PRISM
  • NSF S-STEM
• with all STEM disciplines, community college
  partners


                                           MSU Chem Seminar
                                            17 October 2012
Degree Production 2002-2007

                Degrees                US         MO

             STEM BA/BS +15% -13%
                     AA               -25% -48%
         Source: NSF Science and Engineering Indicators, 2012


 In Missouri, student starting college at 2-year school
intending to transfer and earn a STEM degree have an
               8% chance of succeeding.
                 Source: CBHE IFC Baseline Report               MSU Chem Seminar
                                                                 17 October 2012
MSU Chem Seminar
 17 October 2012
MSU Chem Seminar
 17 October 2012
Composition (%) of U.S. college-age cohort: 1990–2020

  100

   90

   80

   70
                                                            American Indian/Alaska Native
   60                                                       Asian/Pacific Islander
   50                                                       Black
                                                            Hispanic
   40
                                                            White
   30

   20

   10

    0
        1990 1995 2000 2005 2010 2015 2020

               NSF Science and Engineering Indicators 2006, Figure O-37         MSU Chem Seminar
                                                                          TU-HHMI Conference 2012
                                                                                17 October 2012
Missouri EPSCoR
• Missouri is an EPSCoR State
 • NSF funding must not exceed 0.75% of total NSF
    funding (criteria, table)
  • Missouri’s planning process for a Track I grant lead
    by MU’s Bob Duncan ($20m over 5 years)
• This summer, representatives of institutions were
  invited to participate in process of creating the
  proposal
  • scientific with robust workforce development and
    training elements                           MSU Chem Seminar
                                                 17 October 2012
Missouri EPSCoR
• A proposal was submitted on 3 October.
• “Accelerating Bioscience Discovery:
  Learning, Inference, and Modeling”
 • data-intensive bioscience
 • imaging and environmental sensing
• training and workforce development aspects
  are unclear

                                           MSU Chem Seminar
                                            17 October 2012
Missouri EPSCoR
• Gary Meints and I worked together at the
  workshop
• saw an opportunity for Truman and MSU to
  collaborate
• interdisciplinary training of undergraduates
  in STEM using research experiences




                                            MSU Chem Seminar
                                             17 October 2012
Opportunities
• Missouri political and financial climate favors
  collaborations between Universities
• NSF funding favors partnerships
• 21st century professions are integrative,
  interdisciplinary, and team-based
• research on cognitive development
  (learning) shows strengths of undergraduate
  research

                                              MSU Chem Seminar
                                               17 October 2012
What can we do in partnership?




                             MSU Chem Seminar
                              17 October 2012
http://mathbio.truman.edu




More details: Miller, Walston. Interdisciplinary Training in
Mathematical Biology Through Team-based Undergraduate
Research and Courses. CBE Life Sci Educ. 2010 Fall;9(3):284-9.
                                                      MSU Chem Seminar
                                                       17 October 2012
http://mathbio.truman.edu




This material is based upon work supported by the National Science Foundation under NSF
UBM #0337769, #0436348, and #0926737.             Any opinions, findings, and conclusions or
recommendations expressed in this material are those of the author(s) and do not necessarily
reflect the views of the National Science Foundation.

                                                                                 MSU Chem Seminar
                                                                                  17 October 2012

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A Research-based Model for Interdisciplinary Training of STEM Undergraduat…

  • 1. A Research-based Model for Interdisciplinary Training of STEM Undergraduates Jason Miller, Ph.D. Department of Mathematics Truman State University Missouri State University Chemistry Seminar 17 October 2012 MSU Chem Seminar 17 October 2012
  • 2. MSU Chem Seminar 17 October 2012
  • 3. Outline • Introduce Truman State University • Story of Truman’s research-focused mathematical biology program • Truman’s interdisciplinary STEM efforts degree • Opportunities for Collaboration MSU Chem Seminar 17 October 2012
  • 4. Truman Truman is in rural Kirskville, Missouri MSU Chem Seminar 17 October 2012
  • 5. Truman MSU Chem Seminar 17 October 2012
  • 6. About Truman • Missouri’s only “highly selective” public liberal arts University; pride in high-quality teaching, small class size • ~6000 undergraduates, ~300 faculty, 150 Masters students • Institutional commitment to Undergraduate Research and to Interdisciplinary teaching • EX: all students must take a Junior Interdisciplinary Seminar MSU Chem Seminar 17 October 2012
  • 7. About Truman • about 25 biology faculty, 35 mathematics faculty (math+stats+CS) • biology: research expected of faculty (with students); experienced mentors • mathematics: teaching focus, little or no support for research activity; 10 new faculty between 1998-2000 MSU Chem Seminar 17 October 2012
  • 8. MSU Chem Seminar 17 October 2012
  • 9. Professional Societies MSU Chem Seminar 17 October 2012
  • 10. 2003 MSU Chem Seminar 17 October 2012
  • 11. 2007 MSU Chem Seminar 17 October 2012
  • 12. R E P OR T T O T H E PR E SI DEN T ENGAGE TO E XCEL: PRODUCI NG ONE M ILLION A DDI T IONA L COLLEGE GR A DUAT ES W I T H DEGR EES I N SCIENCE , T ECH NOLOGY, ENGI NEER I NG, A N D M AT HEM AT ICS Executive Office of the President President’s Council of Advisors on Science and Technology F E BRUA RY 2 01 2 MSU Chem Seminar 17 October 2012
  • 13. MSU Chem Seminar 17 October 2012
  • 14. Mathematical Biology Seminar (since 2003) • Program fulcrum • Biweekly meeting of faculty and undergraduates • Initially, a “Biology Fashion Show” • Engineered several cross-disciplinary, research hook-ups • Pairings provided us with a foundation for NSF UBM grant proposals MSU Chem Seminar 17 October 2012
  • 15. MSU Chem Seminar 17 October 2012
  • 16. Mathematical Life Scientist Scientist (faculty) (faculty) Mathematical Life Scientist Scientist (trainee) (trainee) MSU Chem Seminar 17 October 2012
  • 17. Mathematical Life Scientist Scientist (faculty) (faculty) Mathematical Life Scientist Scientist (trainee) (trainee) MSU Chem Seminar 17 October 2012
  • 18. MSU Chem Seminar 17 October 2012
  • 19. Mathematical Mathematical Life Scientist Life Scientist Scientist Scientist (faculty) (faculty) (faculty) (faculty) Mathematical Mathematical Life Scientist Life Scientist Scientist Scientist (trainee) (trainee) (trainee) (trainee) Mathematical Mathematical Life Scientist Life Scientist Scientist Scientist (faculty) (faculty) (faculty) (faculty) Mathematical Mathematical Life Scientist Life Scientist Scientist Scientist (trainee) (trainee) (trainee) (trainee) MSU Chem Seminar 17 October 2012
  • 20. • selection occurs in the Fall, students start work in January (year-long) • weekly meetings during the academic year • Intense 10-week summer research program MSU Chem Seminar 17 October 2012
  • 21. Summer Residence Hall Meals Small Group Meetings + Mentors Community Weekly Discussions/Workshops Social Events MathBio Seminar MSU Chem Seminar 17 October 2012
  • 22. Automatic Annotation of Maize Genome Collaboration between Truman, IA State, Cornell, Cold Spring Harbor. MSU Chem Seminar 17 October 2012
  • 23. Automatic Annotation of Maize Genome Collaboration between Truman, IA State, Cornell, Cold Spring Harbor. MSU Chem Seminar 17 October 2012
  • 24. Geometric Modeling of C.elegan’s 4-cell stage MSU Chem Seminar 17 October 2012
  • 25. Graph Theoretic Modeling of Vascular Networks Collaboration between Truman and AT Still University of Health Sciences. MSU Chem Seminar 17 October 2012
  • 26. Modeling Dispersion of Extinct Saccate Pollen Collaboration between Truman and the College of New Jersey. MSU Chem Seminar 17 October 2012
  • 27. Identifying Volant Bats via Echolocation with Lynn Robbins, MSU Biology MSU Chem Seminar 17 October 2012
  • 28. Habitat Suitability modeling for the Missouri Bladderpod Collaboration between Truman and the US Fish and Wildlife Service. MSU Chem Seminar 17 October 2012
  • 29. Statistical Modeling of Abundance of Beetle Populations MSU Chem Seminar 17 October 2012
  • 30. Models of Tick Respiration and Physiology MSU Chem Seminar 17 October 2012
  • 31. • A modified Tajima-D statistic for identifying causes of HIV mutation • Modeling host-parasite interaction in a long- term site study • Geometric modeling of gravitropic sensitivity in flax roots MSU Chem Seminar 17 October 2012
  • 32. Sustainability • an expensive program ($25k per team) • low throughput • high impact • wanted to pursue tactics for long-term sustainability MSU Chem Seminar 17 October 2012
  • 33. Core Courses • Bioinformatics • Introduction to Mathematical Biology • Biostatistics/Biometry • Introduction to Computational Science* • Calculus & Math Methods for the Life Sciences MSU Chem Seminar 17 October 2012
  • 34. Interdisciplinary Minor • Designed to foster thoughtful integration of skills and knowledge in mathematics and biology • outcome based (electronic portfolio), not course/credit based • for majors in biology, mathematics, computer science, agricultural science MSU Chem Seminar 17 October 2012
  • 35. Minor’s Outcomes • Data Acquisition • Modeling • Computation • Statistics • Research MSU Chem Seminar 17 October 2012
  • 36. Requirements • Demonstrate proficiencies in each category (though research, courses) • Earn 15+ credits doing so (must take Intro to MathBio course) • Attend MathBio Seminar • Participate in two half-semester program workshops/seminars MSU Chem Seminar 17 October 2012
  • 37. Other Courses • Any that makes a connection between the areas. Some example: • Math Modeling • Ecology • Developmental Biology • ODEs • Genetics of • (Electron) Microscopy Animal and Plant Improvement Each student makes a case for each course in their learning plan. MSU Chem Seminar 17 October 2012
  • 38. Accomplishments: Strong summer research community. Quality new courses: Bioinformatics, Intro to MathBio, Biostatistics, Intro to Computational Science, Calculus & Math Methods for Life Science Competency-based minor in mathematical biology. Faculty embrace interdisciplinary approaches to research. MSU Chem Seminar 17 October 2012
  • 39. MathBio Notes • Program grew from institutional strengths and interests, meeting the needs of many • Creates a learning-centered community for faculty and students • Trains students through research; discomfort is a sign of success MSU Chem Seminar 17 October 2012
  • 40. • Our program was the perfect means for developing infrastructure and faculty buy-in • It is an imperfect model for a sustainable quantitative or mathematical biology program • (But it puts us in a very powerful position as Truman launches it next efforts.) MSU Chem Seminar 17 October 2012
  • 41. More details: Miller, Walston. Interdisciplinary Training in Mathematical Biology Through Team-based Undergraduate Research and Courses. CBE Life Sci Educ. 2010 Fall;9(3):284-9. MSU Chem Seminar 17 October 2012
  • 42. STEM Talent Expansion Programs (STEP) Office MSU Chem Seminar 17 October 2012
  • 43. 2003 MSU Chem Seminar 17 October 2012
  • 44. 2007 MSU Chem Seminar 17 October 2012
  • 45. R E P OR T T O T H E PR E SI DEN T ENGAGE TO E XCEL: PRODUCI NG ONE M ILLION A DDI T IONA L COLLEGE GR A DUAT ES W I T H DEGR EES I N SCIENCE , T ECH NOLOGY, ENGI NEER I NG, A N D M AT HEM AT ICS Executive Office of the President President’s Council of Advisors on Science and Technology F E BRUA RY 2 01 2 MSU Chem Seminar 17 October 2012
  • 46. STEM Talent Expansion • Truman has leveraged training through undergraduate research for other programs • NSF STEP • NSF PRISM • NSF S-STEM • with all STEM disciplines, community college partners MSU Chem Seminar 17 October 2012
  • 47. Degree Production 2002-2007 Degrees US MO STEM BA/BS +15% -13% AA -25% -48% Source: NSF Science and Engineering Indicators, 2012 In Missouri, student starting college at 2-year school intending to transfer and earn a STEM degree have an 8% chance of succeeding. Source: CBHE IFC Baseline Report MSU Chem Seminar 17 October 2012
  • 48. MSU Chem Seminar 17 October 2012
  • 49. MSU Chem Seminar 17 October 2012
  • 50. Composition (%) of U.S. college-age cohort: 1990–2020 100 90 80 70 American Indian/Alaska Native 60 Asian/Pacific Islander 50 Black Hispanic 40 White 30 20 10 0 1990 1995 2000 2005 2010 2015 2020 NSF Science and Engineering Indicators 2006, Figure O-37 MSU Chem Seminar TU-HHMI Conference 2012 17 October 2012
  • 51. Missouri EPSCoR • Missouri is an EPSCoR State • NSF funding must not exceed 0.75% of total NSF funding (criteria, table) • Missouri’s planning process for a Track I grant lead by MU’s Bob Duncan ($20m over 5 years) • This summer, representatives of institutions were invited to participate in process of creating the proposal • scientific with robust workforce development and training elements MSU Chem Seminar 17 October 2012
  • 52. Missouri EPSCoR • A proposal was submitted on 3 October. • “Accelerating Bioscience Discovery: Learning, Inference, and Modeling” • data-intensive bioscience • imaging and environmental sensing • training and workforce development aspects are unclear MSU Chem Seminar 17 October 2012
  • 53. Missouri EPSCoR • Gary Meints and I worked together at the workshop • saw an opportunity for Truman and MSU to collaborate • interdisciplinary training of undergraduates in STEM using research experiences MSU Chem Seminar 17 October 2012
  • 54. Opportunities • Missouri political and financial climate favors collaborations between Universities • NSF funding favors partnerships • 21st century professions are integrative, interdisciplinary, and team-based • research on cognitive development (learning) shows strengths of undergraduate research MSU Chem Seminar 17 October 2012
  • 55. What can we do in partnership? MSU Chem Seminar 17 October 2012
  • 56. http://mathbio.truman.edu More details: Miller, Walston. Interdisciplinary Training in Mathematical Biology Through Team-based Undergraduate Research and Courses. CBE Life Sci Educ. 2010 Fall;9(3):284-9. MSU Chem Seminar 17 October 2012
  • 57. http://mathbio.truman.edu This material is based upon work supported by the National Science Foundation under NSF UBM #0337769, #0436348, and #0926737. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation. MSU Chem Seminar 17 October 2012