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AMI, Inc.
       Improving Healthcare
       Through Automation



  Improving Healthcare
Outcomes & Reducing Costs
     through Medical
  Automation & Robotics
 WPI Venture Forum
     May 11, 2010
Medical Automation & Robotics


Past through Present
Opportunities
Technologies
Venues
Summary
References
                       2
                           AMI, Inc.
                           Improving Healthcare
                           Through Automation
Definitions

Robot Definitions vary. There is a general consensus of the essential robot
  characteristics:
  Sensors — Robots employ sensing technology to acquire information
  about their environment.
  Intelligence — Robots process information captured through sensor
  technology and produce outputs for decision making, coordination and
  control.
  Motion — Robots automatically follow instructions that are pre-
  programmed, or generated in real-time based on sensor input, to perform
  deliberate, controlled, and often repeated, mechatronic action
Robotics for Medicine and Healthcare is considered the domain of
  systems able to perform coordinated mechatronic actions (force or
  movement exertions) on the basis of processing of information
  acquired through sensor technology, with the aim to support the
  functioning of impaired individuals, medical interventions, care
  and rehabilitation of patients and also to support individuals in
  prevention programs.
                                   3
                                                               AMI, Inc.
                                                               Improving Healthcare
                                                               Through Automation
Robotics: Ancient History

Automatons
Early automated device in antiquity
Ancient Alexandria, Egypt
    Herron of Alexandria wrote 5 books
    Recent discoveries demonstrated
    •   Automated doors
    •   Flying chariots
    •   Entertainment robotic theatres
Ancient Greeks
Ancient Chinese
Leonardo da Vinci
   Lion walk across floor and present flowers to the king

                                  4
                                                            AMI, Inc.
                                                            Improving Healthcare
                                                            Through Automation
Medical Automation & Robotics:
        History
1920-30s   “Dumb” machines



1940-50s   Computers developed


           1st Industrial Robot        Fantastic Voyage’
1960-70s   GM: Unimate                 Movie


           1st Lap                 Puma 560:            SRI: Robotics &
1980s      Cholecystectomy         TURP                 Telemanipulation


1990s      ROBODOC from ISS            AESOPTM          da Vinci of Intuitive Surgical


2000s      Computer Motion & Intuitive Surgical Merge      Hansen, Stereotaxis


                                   5
                                                                      AMI, Inc.
                                                                      Improving Healthcare
                                                                      Through Automation
Medical Automation & Robotics:
       Opportunity




Minimally invasive procedures for
these surgeries in yellow late ’90’s

                                       6
                                           AMI, Inc.
                                           Improving Healthcare
                                           Through Automation
Growing Unmet Health Needs




Courtesy Robotics Business Review © 2009

                                           7
                                               AMI, Inc.
                                               Improving Healthcare
                                               Through Automation
Growing Clinician Needs

Clinician Shortages:                  Potential Solutions:
  Patient - Nurse Ratio
                                        improving education
  Aging population
  population growth
                                        increasing job security
  average age of nurses                 reverse bidding
  changes in opportunities for          staffing by a free agency
  women
                                        increasing wages
  enrollment in nursing schools
  high RN turnover rate
  restrictions on work visas
  understaffed nursing schools

                                  8
                                                        AMI, Inc.
                                                        Improving Healthcare
                                                        Through Automation
Market Drivers

                                        Technology Drivers
Social Drivers                            Increasing Computer Power
  Increasing disabled                     Imaging – 2D and 3D
  Aging Population/Caregiver              Pattern Recognition
  demands                                 Haptics - Palpation
  Boomer expectations, demands,           Advanced Materials
  money and political clout               MEMS/Nanotechnology
  Litigious society                       Miniature Actuators
                                          Sensors
Business/Clinical Drivers                 Human Factors Interface
  Costs – Procedure and Economic
  Reimbursement/Payors
  Clinical Labor shortage
  MIS Demand
  Quality, Reliability and Safety
     Precision
                                    9
                                                           AMI, Inc.
     Repeatability                                         Improving Healthcare
                                                           Through Automation
Barriers to Entry


Business/Clinical Barriers
 Market Need - Moving Target
 Reimbursement/Payors – CPT, ICD9, DRG
 Intellectual Property
 Competition
 Expense of Development
 Investors -> ROI
 Liability
 User acceptance/ease-of-use => data overload
 Regulatory Approval – FDA, ISO
 Clinical Trials
 Politics

                         10
                                                AMI, Inc.
                                                Improving Healthcare
                                                Through Automation
Medical Automation & Robotics:
   Opportunity Costs
Better Healthcare Together report asserted
  Broadband-based applications could save the US
  $197 billion over next twenty five years.
  Economist Robert Litan based savings on reducing ED
  visits, hospitalizations, and length of stay in hospitals
  Based on large population chronic diseases: congestive
  heart failure, diabetes, COPD, and chronic skin
  conditions.
  Reimbursement issues are a critical issue to solve
  Bringing broadband into more homes is a limiting
  factor


                           11
                                                     AMI, Inc.
                                                     Improving Healthcare
                                                     Through Automation
Medical Automation & Robotics:
           Opportunity
                Number of      Expense           Baseline Savings   Policy Savings     Gain from
                 Patients                                                             Policy Change

Heart       3.8 million     $3.8 billion         $79.7 billion      $102.5 billion     $22.8 billion
Patients
Diabetes    2.8 million     $2.8 billion         $42.3 billion      $54.4 billion      $12.1 billion
Patients

COPD        3.4 million     $3.4 billion         $18.7 billion      $24.1 billion      $5.4 billion
Patients

Chronic     0.1 million     $0.1 billion         $12.5 billion      $16.0 billion      $3.5 billion
Wound
Patients


Total:      10.1 million    $10.1 billion        $153.2 billion     $197 billion       $43.8 billion




                                            12
                                                                                     AMI, Inc.
                                                                                     Improving Healthcare
                                                                                     Through Automation
Major Opportunity Areas


Ambulatory
Behavior/Social – Autism, Elderly
Clinical Care – Facilities, Nursing, Point-of-Care
Dental – CAD, Precision Hardware (Braces)
Emergency – ER, Accident, Battlefield
High Throughput Screening for New Drugs
Home – Social, Entertainment, Connectivity
Rehabilitation – Limb, Stroke
Surgery – CAS, Simulation Training, Telesurgery
Telemedicine                                       AMI, Inc.
                            13
                                                   Improving Healthcare
                                                   Through Automation
Classes of Healthcare Robotics

 Robotics                    Robotic Technology to Support Patients
 Technology That
 Support Doctors,
 Surgeons, Dentists

                             Robotic                    Robotic              Robotic Technology
                             Technologies For           Technologies For     That Supports
                             Temporary Use              Continual Use        Infrastructure
 Robotic Interventional      Robotic                    Robotic Assistive    Robotic Hospital
 Systems                     Rehabilitation/            Technology Systems   Automation Systems
                             Therapeutic Systems
 Robotic                     Robotic Support            Robotic Prosthetic   Robotic Smart Living
 Learning/Training           Systems                    and Orthotic         Spaces
 Systems                                                Systems
 Robotic Diagnostic          Robotics Nursing           Robotics Lifestyle   Robotic Laboratory
 Systems                     Assistants                 Enhancement          Automation
                                                        Systems
                             Robotics Surgical
                             Assistants



Courtesy Robotics Business Review © 2009
                                                   14
                                                                                           AMI, Inc.
                                                                                           Improving Healthcare
                                                                                           Through Automation
Medical Venues: Acute to Ambulatory



Accident and Battlefield – Ambulance, Medic
Emergency Room (ER)
Operating Room (OR)
Hospital – Facilities, Nursing, POC
Clinical Laboratory
Rehabilitation and Long-Term Care
Physician Office: Point-of-Care
Home and Ambulatory

                    15
                                       AMI, Inc.
                                       Improving Healthcare
                                       Through Automation
Ba




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                    16
                                                                             Cost vs. Venue




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                                                                                              Cost vs. Venue




                           AMI, Inc.
    Through Automation
    Improving Healthcare
Ambulance and Emergency

Requirements:
  Locate patients
  Evaluate patients’ injuries/disease
  Stabilize and prepare patients for transfer
  Monitor and transport patient and passengers to ER
  Patient data communication w/physician + facility

Solutions:
  Portable Vitals Monitoring Systems
  Automated Dispatch Calling System
  Servo-Controlled ambulance bed
  VECNA Bear Robot for lifting some patients

                            17
                                                       AMI, Inc.
                                                       Improving Healthcare
                                                       Through Automation
Ambulance - Battlefield

     Diagnostic and Therapeutic Instrument
        Diagnose a battlefield injury based on biomarkers
       in body fluids
       Automatically releases appropriate drugs
     By Clarkson University



                              Explosion Sensor
                               Disposable plastic strip, with
                              embedded sensors
                               Measure explosive power
                               Strip fits onto a soldier's helmet
                               Cost < $1
                               Records 1 week’s experience
                              DARPA funded the Palo Alto Research Center's
                               development


                     18
                                                             AMI, Inc.
                                                             Improving Healthcare
                                                             Through Automation
Ambulance - Battlefield




         19
                      AMI, Inc.
                      Improving Healthcare
                      Through Automation
Ambulance - Emergency




Heartstart Portable Defibrillator
     Life-Saving Technology
     Automated for any user                                  RFID system
                                    IntelliVue MP2 Patient     Emergency vehicles
             by Philips
                                            Monitor            inventory control
                                           By Philips        by ThinkMagic developed



                                          20
                                                                       AMI, Inc.
                                                                       Improving Healthcare
                                                                       Through Automation
Emergency Room

Requirements:                             Solutions:
  Determine and diagnose                    RFID Systems to track instruments
  Patients’ injuries/disease                Vitals Monitoring Systems
  Stabilize patients                        Imaging Systems
  Treat patients
                                                        Penelope
  Prepare for transfer to OR, room,
home, or step-down facility


       ER and Surgical Assistant: Penelope Robotic
       Nurse
       By Robotic Systems & Technologies

                                     21
                                                                   AMI, Inc.
                                                                   Improving Healthcare
                                                                   Through Automation
Surgical Applications
                                              Cyberknife
Applications
  Abdominal/GYN (AESOP, da Vinci)
  Cancer (Cyberknife Radiosurgery)
  Cardiac/Pulmonary/Thoracic/Vascular
   (Hansen, Stereotaxis)
  Neurosurgical (Neuromate)
  NOTES (NeoGuide)
  Orthopedic, Spine (RoboDoc, Mako Surgical,
  Mazor)
                           First unmanned telesurgery
  Urological               involving a robotic surgeon and
  Pediatric                a robotic scrub technician


                                         22
                                                             AMI, Inc.
                                                             Improving Healthcare
                                                             Through Automation
Operating Room

OR Surgical Requirements:               Solutions:
  Avoid injury / do no harm               RFID Systems to track
     Controlled Precise movements         instruments
     No tremor                            Vitals Monitoring Systems
     No fatigue                           Imaging Systems
  Clear visualization                     Hi-Res, Large Display
     Provide unambiguous view             Monitors
     Different view perspectives
                                          Surgical Navigations Systems
  Maintain Patient stabilization
     Vital signs remain normal            Robotic Surgical Systems
     Alter vitals as required
  Reduced surgeon physical strain
  Surgical instrument access
  Instrument cleaning and
  sterilization
  Be prepared for unexpected                            AMI, Inc.
                                   23
                                                        Improving Healthcare
                                                        Through Automation
Operating Room: Past




                                             Intuitive Surgical’s
                                                                        Using the da Vinci Surgical
                                             da Vinci Surgical System
                                                                        System

Computer Motion’s
AESOP                                                                   Image Guidance
                                                                            Optical: BrainLab,
                                                                            Medtronic
                    Armstrong Healthcare’s                                  Electromagnetic: GE
                    EndoAssist


                                                  24
                                                                                   AMI, Inc.
                                                                                   Improving Healthcare
                                                                                   Through Automation
Operating Room: Present




Stereotaxis Robot                      Hansen Medicals’ Sensei Robot




                               25
                                                              AMI, Inc.
                    Mako Surgical Robot                       Improving Healthcare
                    w/Orthopedic Implant                      Through Automation
Operating Room: Future


Robot Arm from
Carnegie Mellon Institute




                                                 by Johns Hopkins University

                   by Johns Hopkins University   Steady-hand Robot
                                                 System
                Snake-like robot                    Surgeons will inject
                  Features two thin rods         vision-saving drugs into
                                                 vision-
                  Tipped with tentacle-like
                              tentacle-          tiny blood vessels in the
                tools                            eye in the future
                  Six degrees of freedom
                                     26
                                                                 AMI, Inc.
                                                                 Improving Healthcare
                                                                 Through Automation
Operating Room: Future




                             Microbot (Credit: Image courtesy of
ePill  by Philips
                             Institute of Physics)
Research
  Deliver a drug to a           Analyze vascular wall
precise location in
                                Stop inflammation
the GI tract
  Will soon test in             Treat blockages
animals

                        27
                                                       AMI, Inc.
                                                       Improving Healthcare
                                                       Through Automation
Operating Room: Future


MIS Mitral
valve repair
Robotic
System
  Minimally
Invasive
 Beating
Heart                            PneuStep Biopsy Robot    by Johns Hopkins
by Harvard and                   Urology Robotics Lab
Children's Hospital
of Boston
                                     Can do organ biopsies during MRI scans




                                28
                                                             AMI, Inc.
                                                             Improving Healthcare
                                                             Through Automation
Clinical Laboratory

Requirements
 Accurate
 Repeatable
 Fast Response
 Sufficient Capacity to meet
 clinicians’ needs
                               New Microfluidics Analyzer
 Maintenance & Service
                                 Requires only a drop of blood
                                 Tests for 35 proteins
                                 Results in ten minutes
                                 by Caltech and Institute for Systems Biology




                         29
                                                                 AMI, Inc.
                                                                 Improving Healthcare
                                                                 Through Automation
Clinical Facilities

Requirements                                    Solutions
  Patient Tracking        Equipment tracking     RFID Systems
      Entry                  Location            Facility Robots
      Procedures w/info      Maintenance
                                                 eHealth Records
      Location               Recall status
                                                 Vitals monitors
      Health status       Medicine delivery
      Study participant   Laundry pickup and
      Exit –              delivery
      w/instructions      Food delivery and
      Follow-up           dish-utensil pickup
                          Instrument
                             Cleaning
                             Sterilization

                                 30
                                                       AMI, Inc.
                                                       Improving Healthcare
                                                       Through Automation
Hospital




Helpmate - ATLIS (Automated                Roving Physician
Transport and Logistics Integration        By InTouch Health
Systems) by FMC


                                      31
                                                       AMI, Inc.
                                                       Improving Healthcare
                                                       Through Automation
Hospital




Swisslog’s PillPick system                   Swisslog's BoxPicker
  Bar-code packages                            High-density, automated
                                               pharmacy
  Stores and dispenses unit dose
  medications                                  Warehouse for the storage and
                                               dispensing of medications
  Unit doses are automatically placed
  by Pill Picker                               Refrigerated medications, and
                                               supplies

                                        32
                                                                       AMI, Inc.
                                                                       Improving Healthcare
                                                                       Through Automation
Hospital
WORLD'S LARGEST
TELEPHARMACY, THE US NAVY




                   33
                            AMI, Inc.
                            Improving Healthcare
                            Through Automation
Point Of Care – Doctor’s Office

Requirements             Solutions
  Patient Care               Discrete Instruments with
     Diagnose                       enhanced sensors
     Therapy                        data
     Refer                          display

  Business and Admin         EMR (Health IT, e-Health)
                             Business Software
                             21st Century Stethoscope


                       Accuson P10
                       handheld                          Signos Personal
                       ultrasound                        Ultrasound System
                                                         by Signostics
                       By Siemens


                                           34
                                                                   AMI, Inc.
                                                                   Improving Healthcare
                                                                   Through Automation
Point Of Care – Doctor’s Office




             35
                          AMI, Inc.
                          Improving Healthcare
                          Through Automation
Rehabilitation

          Requirements
             Patient Care
                 Therapy
                 Feedback, Track Progress
                 Back to optimum health
             Onsite and at home
             Business and Admin




                                               Myomo: Robots empower
                                               patient at home

Intelligent Robotic Facilitator
                                          36
                                                                 AMI, Inc.
                                                                 Improving Healthcare
                                                                 Through Automation
Rehabilitation




Repetitive task practice
                                A Manhattan Project for
Patient controlled              the Prosthetic Arms Race



                           37
                                                     AMI, Inc.
                                                     Improving Healthcare
                                                     Through Automation
Home, Ambulatory –
             CARE EVERYWHERE

ISSUES                   SOLUTIONS
 Healthcare Costs             Maximize Health outside
   17% GDP
   20% by 2020
                              clinical settings
                                Prevention
 Chronic conditions
   75% of the nation’s          Remote Rehab
   health care costs            Remote Monitoring
REQUIREMENTS                      Health IT, EHR, Telehealth
                                  Connectivity
   Reduce Costs                   Security
   Improve Health                 Transparency
                         38
                                                    AMI, Inc.
                                                    Improving Healthcare
                                                    Through Automation
Home, Ambulatory –
            CARE EVERYWHERE

MEDICATION COMPLIANCE
 > 1/2 the elderly population suffer from one or
 more chronic illnesses
 they have been prescribed ≥ 3 medications.
 Non-compliance costs over $150 billion per year
 in the U.S.
 challenge of remembering how to take the
 medications properly

                       39
                                         AMI, Inc.
                                         Improving Healthcare
                                         Through Automation
Home, Ambulatory –
         CARE EVERYWHERE




"Equivital“
 Wearable vital signs monitor        OmniPod Insulin Management System
                                     By Insulet Corporation
 Measures and transmits
     Heart rate
     Two lead ECG
     Respiration
     Temperature
     Blood oxygen saturation
                                40
                                                              AMI, Inc.
     Fall detection                                           Improving Healthcare
                                                              Through Automation
Home, Ambulatory –
 CARE EVERYWHERE

Fitbit
  Small size
  pedometer
  Clipped on
  clothes or a
  wristband
                                              University of South Florida
  24/7
  monitoring                                 Real Time
  Wireless data                              Location System
                  Corventis - PiiX,
  upload for                                   Test movement
  analysis        • 15-centimeter patch      monitoring
                  that applied directly to     Early indication of
                  the patient’s chest.       dementia
                  • It measures real-time
                  heart rate, body
                  temperature, physical
                  activity, body position,
                  respiration rate, and
                        41
                                                      AMI, Inc.
                                                      Improving Healthcare
                  body fluid levels                   Through Automation
Home, Ambulatory –
                                       CARE EVERYWHERE
        Courtesy: Medical Automation




SENSORED CONTACT LENS
DETECTS GLAUCOMA
• High intraocular pressure is a sign
of developing glaucoma
                                          Toto's new Intelligence Toilet II monitors weight, blood sugar
• ophthalmologists have means for         levels, and other vital signs, transferring data to your computer
measuring that pressure, nut not          for analysis via WiFi
continuous readings.
                                                    42
                                                                                           AMI, Inc.
•Swiss company, Sensimed                                                                   Improving Healthcare
                                                                                           Through Automation
(Lausanne) has a sensor-embedded
.
Point Of Care – Doctor’s Office




             43
                          AMI, Inc.
                          Improving Healthcare
                          Through Automation
Future


Tissue Engineering + MEMS/NANO + Electronics + Mechanics +
   Biologics + Microbiology =>
   Life Supporting Systems – Limbs
   Life Sustaining Systems – Organs
   RoboSapiens or Humobots – Integration of systems and humans

RESULTS
  Improved QOL
  Extend Life
  New life



                               44
                                                     AMI, Inc.
                                                     Improving Healthcare
                                                     Through Automation
SUMMARY: Key Steps to Success

Business                         Customer
  Market Need - Moving Target      Level of skill, knowledge
  Clinical/Client Adoption         User acceptance/ease-of-
                                   use, Pervasive
  Business Models – Who
  Pays?                            DATA – Fragmented,
                                   Overload vs.
  Reimbursement/Payors –           Understandable, Usable
  CPT, ICD9, DRG
                                   Clinical Trials
  Regulatory Approval – ISO-
  like Intellectual Property
  Competition / Alliance
  Expense of Development
  Investors -> ROI
  Liability

                            45
                                                     AMI, Inc.
                                                     Improving Healthcare
                                                     Through Automation
Website References

             Organization                                        URL
American College of Surgeons (ACS)         http://www.facs.org
American Telemedicine Association          http://www.atmeda.org
(ATA)
Medical Robotics and Computer Aided        http://www.mrcas.ri.cmu.edu
Surgery (MRCAS)
Minimally Invasive Robotic Association     http://www.mira2008.com ;
(MIRA)                                     http://www.miraweb.org /
Robotics Association of America (RIA)      http://www.robotics.org

Robotic Surgery                            http://www.roboticsurgery.com
Society of American Gastrointestinal and   http://www.sages.org
Endoscopic Surgeons (SAGES)
Medical Automation                         http://medicalautomation.org/index.php


                                            46
                                                                           AMI, Inc.
                                                                           Improving Healthcare
                                                                           Through Automation
Medical Automation & Robotics



          Thank You!
          Martin Sklar
Automated Medical Instruments, Inc.
            781-248-6841
       msklar@automedinst.com


                 47
                                AMI, Inc.
                                Improving Healthcare
                                Through Automation

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Improving Healthcare Outcomes &amp; Reducing Costs Through Medical Automation

  • 1. AMI, Inc. Improving Healthcare Through Automation Improving Healthcare Outcomes & Reducing Costs through Medical Automation & Robotics WPI Venture Forum May 11, 2010
  • 2. Medical Automation & Robotics Past through Present Opportunities Technologies Venues Summary References 2 AMI, Inc. Improving Healthcare Through Automation
  • 3. Definitions Robot Definitions vary. There is a general consensus of the essential robot characteristics: Sensors — Robots employ sensing technology to acquire information about their environment. Intelligence — Robots process information captured through sensor technology and produce outputs for decision making, coordination and control. Motion — Robots automatically follow instructions that are pre- programmed, or generated in real-time based on sensor input, to perform deliberate, controlled, and often repeated, mechatronic action Robotics for Medicine and Healthcare is considered the domain of systems able to perform coordinated mechatronic actions (force or movement exertions) on the basis of processing of information acquired through sensor technology, with the aim to support the functioning of impaired individuals, medical interventions, care and rehabilitation of patients and also to support individuals in prevention programs. 3 AMI, Inc. Improving Healthcare Through Automation
  • 4. Robotics: Ancient History Automatons Early automated device in antiquity Ancient Alexandria, Egypt Herron of Alexandria wrote 5 books Recent discoveries demonstrated • Automated doors • Flying chariots • Entertainment robotic theatres Ancient Greeks Ancient Chinese Leonardo da Vinci Lion walk across floor and present flowers to the king 4 AMI, Inc. Improving Healthcare Through Automation
  • 5. Medical Automation & Robotics: History 1920-30s “Dumb” machines 1940-50s Computers developed 1st Industrial Robot Fantastic Voyage’ 1960-70s GM: Unimate Movie 1st Lap Puma 560: SRI: Robotics & 1980s Cholecystectomy TURP Telemanipulation 1990s ROBODOC from ISS AESOPTM da Vinci of Intuitive Surgical 2000s Computer Motion & Intuitive Surgical Merge Hansen, Stereotaxis 5 AMI, Inc. Improving Healthcare Through Automation
  • 6. Medical Automation & Robotics: Opportunity Minimally invasive procedures for these surgeries in yellow late ’90’s 6 AMI, Inc. Improving Healthcare Through Automation
  • 7. Growing Unmet Health Needs Courtesy Robotics Business Review © 2009 7 AMI, Inc. Improving Healthcare Through Automation
  • 8. Growing Clinician Needs Clinician Shortages: Potential Solutions: Patient - Nurse Ratio improving education Aging population population growth increasing job security average age of nurses reverse bidding changes in opportunities for staffing by a free agency women increasing wages enrollment in nursing schools high RN turnover rate restrictions on work visas understaffed nursing schools 8 AMI, Inc. Improving Healthcare Through Automation
  • 9. Market Drivers Technology Drivers Social Drivers Increasing Computer Power Increasing disabled Imaging – 2D and 3D Aging Population/Caregiver Pattern Recognition demands Haptics - Palpation Boomer expectations, demands, Advanced Materials money and political clout MEMS/Nanotechnology Litigious society Miniature Actuators Sensors Business/Clinical Drivers Human Factors Interface Costs – Procedure and Economic Reimbursement/Payors Clinical Labor shortage MIS Demand Quality, Reliability and Safety Precision 9 AMI, Inc. Repeatability Improving Healthcare Through Automation
  • 10. Barriers to Entry Business/Clinical Barriers Market Need - Moving Target Reimbursement/Payors – CPT, ICD9, DRG Intellectual Property Competition Expense of Development Investors -> ROI Liability User acceptance/ease-of-use => data overload Regulatory Approval – FDA, ISO Clinical Trials Politics 10 AMI, Inc. Improving Healthcare Through Automation
  • 11. Medical Automation & Robotics: Opportunity Costs Better Healthcare Together report asserted Broadband-based applications could save the US $197 billion over next twenty five years. Economist Robert Litan based savings on reducing ED visits, hospitalizations, and length of stay in hospitals Based on large population chronic diseases: congestive heart failure, diabetes, COPD, and chronic skin conditions. Reimbursement issues are a critical issue to solve Bringing broadband into more homes is a limiting factor 11 AMI, Inc. Improving Healthcare Through Automation
  • 12. Medical Automation & Robotics: Opportunity Number of Expense Baseline Savings Policy Savings Gain from Patients Policy Change Heart 3.8 million $3.8 billion $79.7 billion $102.5 billion $22.8 billion Patients Diabetes 2.8 million $2.8 billion $42.3 billion $54.4 billion $12.1 billion Patients COPD 3.4 million $3.4 billion $18.7 billion $24.1 billion $5.4 billion Patients Chronic 0.1 million $0.1 billion $12.5 billion $16.0 billion $3.5 billion Wound Patients Total: 10.1 million $10.1 billion $153.2 billion $197 billion $43.8 billion 12 AMI, Inc. Improving Healthcare Through Automation
  • 13. Major Opportunity Areas Ambulatory Behavior/Social – Autism, Elderly Clinical Care – Facilities, Nursing, Point-of-Care Dental – CAD, Precision Hardware (Braces) Emergency – ER, Accident, Battlefield High Throughput Screening for New Drugs Home – Social, Entertainment, Connectivity Rehabilitation – Limb, Stroke Surgery – CAS, Simulation Training, Telesurgery Telemedicine AMI, Inc. 13 Improving Healthcare Through Automation
  • 14. Classes of Healthcare Robotics Robotics Robotic Technology to Support Patients Technology That Support Doctors, Surgeons, Dentists Robotic Robotic Robotic Technology Technologies For Technologies For That Supports Temporary Use Continual Use Infrastructure Robotic Interventional Robotic Robotic Assistive Robotic Hospital Systems Rehabilitation/ Technology Systems Automation Systems Therapeutic Systems Robotic Robotic Support Robotic Prosthetic Robotic Smart Living Learning/Training Systems and Orthotic Spaces Systems Systems Robotic Diagnostic Robotics Nursing Robotics Lifestyle Robotic Laboratory Systems Assistants Enhancement Automation Systems Robotics Surgical Assistants Courtesy Robotics Business Review © 2009 14 AMI, Inc. Improving Healthcare Through Automation
  • 15. Medical Venues: Acute to Ambulatory Accident and Battlefield – Ambulance, Medic Emergency Room (ER) Operating Room (OR) Hospital – Facilities, Nursing, POC Clinical Laboratory Rehabilitation and Long-Term Care Physician Office: Point-of-Care Home and Ambulatory 15 AMI, Inc. Improving Healthcare Through Automation
  • 16. Ba 0 0.2 0.4 0.6 0.8 1 1.2 t tl ef Em ie er Ac ld ge cid en O n cy t pe R ra o tin om Ac g R ut oo Lo e m ng Ho -T spi er ta m l C ar Ph e 16 Cost vs. Venue y s Re ic ha ia b n O ffi ce H Am om bu e la to ry Cost vs. Venue AMI, Inc. Through Automation Improving Healthcare
  • 17. Ambulance and Emergency Requirements: Locate patients Evaluate patients’ injuries/disease Stabilize and prepare patients for transfer Monitor and transport patient and passengers to ER Patient data communication w/physician + facility Solutions: Portable Vitals Monitoring Systems Automated Dispatch Calling System Servo-Controlled ambulance bed VECNA Bear Robot for lifting some patients 17 AMI, Inc. Improving Healthcare Through Automation
  • 18. Ambulance - Battlefield Diagnostic and Therapeutic Instrument Diagnose a battlefield injury based on biomarkers in body fluids Automatically releases appropriate drugs By Clarkson University Explosion Sensor Disposable plastic strip, with embedded sensors Measure explosive power Strip fits onto a soldier's helmet Cost < $1 Records 1 week’s experience DARPA funded the Palo Alto Research Center's development 18 AMI, Inc. Improving Healthcare Through Automation
  • 19. Ambulance - Battlefield 19 AMI, Inc. Improving Healthcare Through Automation
  • 20. Ambulance - Emergency Heartstart Portable Defibrillator Life-Saving Technology Automated for any user RFID system IntelliVue MP2 Patient Emergency vehicles by Philips Monitor inventory control By Philips by ThinkMagic developed 20 AMI, Inc. Improving Healthcare Through Automation
  • 21. Emergency Room Requirements: Solutions: Determine and diagnose RFID Systems to track instruments Patients’ injuries/disease Vitals Monitoring Systems Stabilize patients Imaging Systems Treat patients Penelope Prepare for transfer to OR, room, home, or step-down facility ER and Surgical Assistant: Penelope Robotic Nurse By Robotic Systems & Technologies 21 AMI, Inc. Improving Healthcare Through Automation
  • 22. Surgical Applications Cyberknife Applications Abdominal/GYN (AESOP, da Vinci) Cancer (Cyberknife Radiosurgery) Cardiac/Pulmonary/Thoracic/Vascular (Hansen, Stereotaxis) Neurosurgical (Neuromate) NOTES (NeoGuide) Orthopedic, Spine (RoboDoc, Mako Surgical, Mazor) First unmanned telesurgery Urological involving a robotic surgeon and Pediatric a robotic scrub technician 22 AMI, Inc. Improving Healthcare Through Automation
  • 23. Operating Room OR Surgical Requirements: Solutions: Avoid injury / do no harm RFID Systems to track Controlled Precise movements instruments No tremor Vitals Monitoring Systems No fatigue Imaging Systems Clear visualization Hi-Res, Large Display Provide unambiguous view Monitors Different view perspectives Surgical Navigations Systems Maintain Patient stabilization Vital signs remain normal Robotic Surgical Systems Alter vitals as required Reduced surgeon physical strain Surgical instrument access Instrument cleaning and sterilization Be prepared for unexpected AMI, Inc. 23 Improving Healthcare Through Automation
  • 24. Operating Room: Past Intuitive Surgical’s Using the da Vinci Surgical da Vinci Surgical System System Computer Motion’s AESOP Image Guidance Optical: BrainLab, Medtronic Armstrong Healthcare’s Electromagnetic: GE EndoAssist 24 AMI, Inc. Improving Healthcare Through Automation
  • 25. Operating Room: Present Stereotaxis Robot Hansen Medicals’ Sensei Robot 25 AMI, Inc. Mako Surgical Robot Improving Healthcare w/Orthopedic Implant Through Automation
  • 26. Operating Room: Future Robot Arm from Carnegie Mellon Institute by Johns Hopkins University by Johns Hopkins University Steady-hand Robot System Snake-like robot Surgeons will inject Features two thin rods vision-saving drugs into vision- Tipped with tentacle-like tentacle- tiny blood vessels in the tools eye in the future Six degrees of freedom 26 AMI, Inc. Improving Healthcare Through Automation
  • 27. Operating Room: Future Microbot (Credit: Image courtesy of ePill by Philips Institute of Physics) Research Deliver a drug to a Analyze vascular wall precise location in Stop inflammation the GI tract Will soon test in Treat blockages animals 27 AMI, Inc. Improving Healthcare Through Automation
  • 28. Operating Room: Future MIS Mitral valve repair Robotic System Minimally Invasive Beating Heart PneuStep Biopsy Robot by Johns Hopkins by Harvard and Urology Robotics Lab Children's Hospital of Boston Can do organ biopsies during MRI scans 28 AMI, Inc. Improving Healthcare Through Automation
  • 29. Clinical Laboratory Requirements Accurate Repeatable Fast Response Sufficient Capacity to meet clinicians’ needs New Microfluidics Analyzer Maintenance & Service Requires only a drop of blood Tests for 35 proteins Results in ten minutes by Caltech and Institute for Systems Biology 29 AMI, Inc. Improving Healthcare Through Automation
  • 30. Clinical Facilities Requirements Solutions Patient Tracking Equipment tracking RFID Systems Entry Location Facility Robots Procedures w/info Maintenance eHealth Records Location Recall status Vitals monitors Health status Medicine delivery Study participant Laundry pickup and Exit – delivery w/instructions Food delivery and Follow-up dish-utensil pickup Instrument Cleaning Sterilization 30 AMI, Inc. Improving Healthcare Through Automation
  • 31. Hospital Helpmate - ATLIS (Automated Roving Physician Transport and Logistics Integration By InTouch Health Systems) by FMC 31 AMI, Inc. Improving Healthcare Through Automation
  • 32. Hospital Swisslog’s PillPick system Swisslog's BoxPicker Bar-code packages High-density, automated pharmacy Stores and dispenses unit dose medications Warehouse for the storage and dispensing of medications Unit doses are automatically placed by Pill Picker Refrigerated medications, and supplies 32 AMI, Inc. Improving Healthcare Through Automation
  • 33. Hospital WORLD'S LARGEST TELEPHARMACY, THE US NAVY 33 AMI, Inc. Improving Healthcare Through Automation
  • 34. Point Of Care – Doctor’s Office Requirements Solutions Patient Care Discrete Instruments with Diagnose enhanced sensors Therapy data Refer display Business and Admin EMR (Health IT, e-Health) Business Software 21st Century Stethoscope Accuson P10 handheld Signos Personal ultrasound Ultrasound System by Signostics By Siemens 34 AMI, Inc. Improving Healthcare Through Automation
  • 35. Point Of Care – Doctor’s Office 35 AMI, Inc. Improving Healthcare Through Automation
  • 36. Rehabilitation Requirements Patient Care Therapy Feedback, Track Progress Back to optimum health Onsite and at home Business and Admin Myomo: Robots empower patient at home Intelligent Robotic Facilitator 36 AMI, Inc. Improving Healthcare Through Automation
  • 37. Rehabilitation Repetitive task practice A Manhattan Project for Patient controlled the Prosthetic Arms Race 37 AMI, Inc. Improving Healthcare Through Automation
  • 38. Home, Ambulatory – CARE EVERYWHERE ISSUES SOLUTIONS Healthcare Costs Maximize Health outside 17% GDP 20% by 2020 clinical settings Prevention Chronic conditions 75% of the nation’s Remote Rehab health care costs Remote Monitoring REQUIREMENTS Health IT, EHR, Telehealth Connectivity Reduce Costs Security Improve Health Transparency 38 AMI, Inc. Improving Healthcare Through Automation
  • 39. Home, Ambulatory – CARE EVERYWHERE MEDICATION COMPLIANCE > 1/2 the elderly population suffer from one or more chronic illnesses they have been prescribed ≥ 3 medications. Non-compliance costs over $150 billion per year in the U.S. challenge of remembering how to take the medications properly 39 AMI, Inc. Improving Healthcare Through Automation
  • 40. Home, Ambulatory – CARE EVERYWHERE "Equivital“ Wearable vital signs monitor OmniPod Insulin Management System By Insulet Corporation Measures and transmits Heart rate Two lead ECG Respiration Temperature Blood oxygen saturation 40 AMI, Inc. Fall detection Improving Healthcare Through Automation
  • 41. Home, Ambulatory – CARE EVERYWHERE Fitbit Small size pedometer Clipped on clothes or a wristband University of South Florida 24/7 monitoring Real Time Wireless data Location System Corventis - PiiX, upload for Test movement analysis • 15-centimeter patch monitoring that applied directly to Early indication of the patient’s chest. dementia • It measures real-time heart rate, body temperature, physical activity, body position, respiration rate, and 41 AMI, Inc. Improving Healthcare body fluid levels Through Automation
  • 42. Home, Ambulatory – CARE EVERYWHERE Courtesy: Medical Automation SENSORED CONTACT LENS DETECTS GLAUCOMA • High intraocular pressure is a sign of developing glaucoma Toto's new Intelligence Toilet II monitors weight, blood sugar • ophthalmologists have means for levels, and other vital signs, transferring data to your computer measuring that pressure, nut not for analysis via WiFi continuous readings. 42 AMI, Inc. •Swiss company, Sensimed Improving Healthcare Through Automation (Lausanne) has a sensor-embedded .
  • 43. Point Of Care – Doctor’s Office 43 AMI, Inc. Improving Healthcare Through Automation
  • 44. Future Tissue Engineering + MEMS/NANO + Electronics + Mechanics + Biologics + Microbiology => Life Supporting Systems – Limbs Life Sustaining Systems – Organs RoboSapiens or Humobots – Integration of systems and humans RESULTS Improved QOL Extend Life New life 44 AMI, Inc. Improving Healthcare Through Automation
  • 45. SUMMARY: Key Steps to Success Business Customer Market Need - Moving Target Level of skill, knowledge Clinical/Client Adoption User acceptance/ease-of- use, Pervasive Business Models – Who Pays? DATA – Fragmented, Overload vs. Reimbursement/Payors – Understandable, Usable CPT, ICD9, DRG Clinical Trials Regulatory Approval – ISO- like Intellectual Property Competition / Alliance Expense of Development Investors -> ROI Liability 45 AMI, Inc. Improving Healthcare Through Automation
  • 46. Website References Organization URL American College of Surgeons (ACS) http://www.facs.org American Telemedicine Association http://www.atmeda.org (ATA) Medical Robotics and Computer Aided http://www.mrcas.ri.cmu.edu Surgery (MRCAS) Minimally Invasive Robotic Association http://www.mira2008.com ; (MIRA) http://www.miraweb.org / Robotics Association of America (RIA) http://www.robotics.org Robotic Surgery http://www.roboticsurgery.com Society of American Gastrointestinal and http://www.sages.org Endoscopic Surgeons (SAGES) Medical Automation http://medicalautomation.org/index.php 46 AMI, Inc. Improving Healthcare Through Automation
  • 47. Medical Automation & Robotics Thank You! Martin Sklar Automated Medical Instruments, Inc. 781-248-6841 msklar@automedinst.com 47 AMI, Inc. Improving Healthcare Through Automation