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Mechanism of action of hormones

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Dr.M.Prasad Naidu
Dr.M.Prasad Naidu

hormones

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Hormone mechanism of action M.Prasad Naidu MSc Medical Biochemistry, Ph.D.Research Scholar
Classification based on mechanism of action • Group 1 : bind to intracellular receptors. eg; Androgens , calcitriol, estrogens , glucocorticoids progestrins thyroid hormones
• Group II: Bind to cell surface receptors . A. Second messenger cAMP ACTH, ADH, hCG, CRH,FSH, LH, PTH. B. cGMP as second messenger. ANF (atrial natriuretic factor) Nitric oxide (NO).
• C. Calcium / phosphatidyl inositols as second messenger GnRH, TRH, PDGF, Substance P. • D. Second messenger is a Kinase /phosphatase cascade Insulin, GH, prolactin , insulin like growth factors(IGF-1,IGF-2).
Mechanism of action of hormones

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Mechanism of action of hormones

  • 1. Hormone mechanism of action M.Prasad Naidu MSc Medical Biochemistry, Ph.D.Research Scholar
  • 2.
  • 3. Classification based on mechanism of action • Group 1 : bind to intracellular receptors. eg; Androgens , calcitriol, estrogens , glucocorticoids progestrins thyroid hormones
  • 4.
  • 5. • Group II: Bind to cell surface receptors . A. Second messenger cAMP ACTH, ADH, hCG, CRH,FSH, LH, PTH. B. cGMP as second messenger. ANF (atrial natriuretic factor) Nitric oxide (NO).
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11. • C. Calcium / phosphatidyl inositols as second messenger GnRH, TRH, PDGF, Substance P. • D. Second messenger is a Kinase /phosphatase cascade Insulin, GH, prolactin , insulin like growth factors(IGF-1,IGF-2).