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12/15/2007




                                                               RSI in Emergency Department

Rapid Sequence Intubation (RSI)                                              Outline
             in
       Emergency Room                                  • Indications for intubation
                                                       • Considerations in Emergency intubation
                                                       • Rapid Sequence Intubation (RSI)
Siriporn Pitimana-aree, MD                             • The Failed Airway
Dept. of Anesthesiology,                               • Defining the Difficult Airway
Faculty of Medicine Siriraj hospital.                  • Rescue Devices
(The Royal College of Anesthesiologists of Thailand)




       Indications for ETT intubation                           Emergency ETT intubation:

                                                                     Considerations
                                                                 • Time pressure
      • Absent or inadequate respiration
                                                                 • Unstable patient
      • Impending airway obstruction                             • Physiologic responses
      • Inability to protect airway                              • Possibly difficult situation
                                                                        • Uncooperative / combative
                                                                        • Not fasted
                                                                        • Difficult airway




         Emergency ETT intubation:


     Physiologic responses to intubation
                                                          • Incidence of difficult & failed intubation: 8%
            •Gagging                                      • Frequency of esophageal intubation: 8%
            •Rise in ICP                                     40% of these - difficult intubation
                                                             almost all recognized by clinical criteria
            •Rise in BP                                       but 3, decrease saturation detected by SpO2
            •Tachycardia / Bradycardia                    • Incidence   of pulmonary aspiration: 4%
            •Dysrhythmias
                                                          • Hemodynamic consequences:
                                                             3% died during or within 30 min. of intubation




                                                                                                                      1
12/15/2007




     Rapid Sequence Intubation (RSI)                Rapid Sequence Intubation (RSI)


              Definition
                                                    Definition Incorporates:

The virtually simultaneous administration         • Every patient has a full stomach
        of a potent sedative agent                • Preoxygenation
   & a neuromuscular blocking agent               • No interposed ventilations
       to induce unconsciousness                  • Sellick’s maneuver
& motor paralysis for tracheal intubation.




     Rapid Sequence Intubation (RSI)                 Rapid Sequence Intubation (RSI)

                                                           Contraindications:
          Advantages of RSI
                                                 Anticipate of difficult airway& intubation
  •Minimizes risk of aspiration
  •Facilitate intubation                         Staff inexperienced in RSI
  •Blunt untoward physiologic responses
  •Avoid awake intubation                        Patients allergic or contraindication to
                                                    drugs used in RSI




     Rapid Sequence Intubation (RSI)                Rapid Sequence Intubation (RSI)

        The Six Ps of RSI                                             10 min
                                             The Sequence
    Preparation                                                    Preparation
    Preoxygenation
    Paralysis with Sedation                                       Preoxygenation
    Protection
    Placement                                the time of
                                             administration of   ………..Zero
    Postintubation care                      Succinylcholine.




                                                                                               2
12/15/2007




    Rapid Sequence Intubation (RSI)            Rapid Sequence Intubation (RSI)

The Sequence …10 minutes ---- Zero     The Sequence …5 minutes ---- Zero

Preparation                            Preoxygenation
  • Assess airway difficulty (LEMON)
                                            • 100% oxygen for five minutes
  • Plan approach
                                            • 8 vital capacity breaths
  • Assemble drugs and equipments
                                            • Provides essential apnea time
  • Establish access
                                            • Apnea time varies
  • Establish monitoring




                                               Rapid Sequence Intubation (RSI)

                                       The Sequence                  Zero!!

                                        Paralysis with Sedation

                                            • Sedative / Induction agent IV push
                                            • Succinylcholine 1.5 mg/kg IV push


                                                   Entering the red zone...




    Rapid Sequence Intubation (RSI)

The Sequence …Zero + 30 seconds

Protection
    • Sellick’s Maneuver
    • Position patient                 Optimal External                 Sellick’s maneuver
    • Do not bag unless SpO2 < 90%     Laryngeal Manipulation           (Cricoid pressure)
                                       (Backwards, Upwards,
                                        Rightwards Position (BURP)




                                                                                              3
12/15/2007




                                                        Rapid Sequence Intubation (RSI)

                                                   The Sequence …Zero + 60 seconds

                                                   Placement
                                                      • Check mandible for flaccidity
                                                      • Intubate, remove stylet
                                                      • Confirm tube placement – EtCO2
                                                      • Release Sellick’s maneuver
                 “ Sniffing position ”




                                                         Rapid Sequence Intubation (RSI)

                                                   The Sequence

                      Experinced   Inexperinced
                                                    Postintubation care
Auscultation            100%             68%         •Ongoing sedation and/or paralysis
 ETCO2                  100%             100%        •Mechanical ventilation (if needed)
Self inflating bulb     96%              98%         •Further investigations (CXR, ABG)
Trachlight              84%              87%         •Postintubation hypotension




                                                         Rapid Sequence Intubation (RSI)
                                                             “Failed intubation”
                         What do you do?
                         If you can not intubate
                         after RSI?                Rescue Maneuvers
                                                   • The first rescue from failed intubation is
                          “Failed intubation”        bagging.
                                                   • The first rescue from failed bagging is
                                                     better bagging.
                                                   • Rescue devices




                                                                                                  4
12/15/2007




         The “Failed” Airway                            The “Failed” Airway


• Multiple Definitions…                       Clinically, 2 types of “failed” airways:
  – Number of failed attempts (e.g., three)
  – Failure to ventilate with a BVM             1. Cannot intubate, but can oxygenate
  – Failure to oxygenate
  – Failure to visualize the larynx             2. Cannot intubate, and cannot
                                                   oxygenate




          The Difficult Airway                           The Difficult Airway

                                               Identification of the Difficult Airway
The DIFFICULT AIRWAY is something you                     3 Key Attributes
             PREDICT…

  A FAILED AIRWAY is something you               • Difficult Bag/Mask Ventilation
           EXPERIENCE!!                          • Difficult Intubation
                                                 • Difficult Cricothyrotomy




           The Difficult Airway
                                                           The Difficult Airway

      Difficult Bag Mask Ventilation                     Difficult Cricothyrotomy
                  Mask seal                                    Surgery scar
                  Obesity                                      Hematoma
                  Aged (>55)                                   Obesity
                  No teeth                                     Radiation
                  Stiff lungs                                  Tumor




                                                                                                 5
12/15/2007




                                                         Predicting of difficult airway
           Difficult Intubation
     Identification of the Difficult Airway
                                                           • A short bull neck
                                                           • Prominent incisors
 • BMV as important as intubation
                                                           • A receding chin
 • Mouth opening/access                                    • Limited mouth opening
 • Neck extension at AOJ                                   • Chin to hyoid distance
 • Neck flexion at CTJ                                       < 6 cm (3FB)
 • Mentum-Hyoid-Thyroid distance                           • Potential C-spine injury
 • Presence/Risk of obstruction                            • Facial deformity
                                                           • Morbid obesity




                                                              Difficult Intubation
            Difficult Intubation
                                                        Identification of the Difficult Airway
     Identification of the Difficult Airway
                                                                 The LEMON law
                                                                   L    ook externally
Development of a consistent approach:                              E    valuate 3-3-2
                                                                   M    allampati
             The LEMON law                                         O    bstruction?
                                                                   N    eck mobility
        © National Emergency Airway Management Course       © National Emergency Airway Management Course




            Difficult Intubation                                 Difficult Intubation
     Identification of the Difficult Airway              Identification of the Difficult Airway

     L ook externally
                                                           E valuate 3-3-2
 - Difficult BMV (MOANS)
 - Difficult Cricothyrotomy (SHORT)                     Or some other thyromental
 - Intubator Gestalt                                        distance equivalent




                                                                                                                    6
12/15/2007




           Difficult Intubation                                Difficult Intubation
     Identification of the Difficult Airway               Identification of the Difficult Airway

              M allampati                                      O bstruction?




                                                             Difficult Intubation
            Difficult Intubation
      Identification of the Difficult Airway         Management of the Difficult Airway
           N eck mobility                            • Need a consistent approach
                                                     • Awake techniques by default
                                                     • Need definition of and preplanned
                                                          approach to failed airway
                                                     • No “one trick pony” approach
                                                     • Alternative devices




           Difficult Intubation

 Management of the Difficult Airway

• Alternative/Rescue devices?
  – Supraglottic: LMA, Combitube
  – Stylet, Gum elastic bougie; GEB
  – Lighted stylets: Trachlight, Lightwand
  – Fiberoptic devices: flexible, rigid, hand-held
  – Surgical: open, transtracheal




                                                                                                    7
12/15/2007




                              L
                              M
                              A

                              I
                              n
                              s
                              e
                              r
                              t
                              i
                              o
                              n
                                                                                Combitube I n s e r t i o n




                                                                                Emergency ETT intubation:
                                                                                    Team members & their roles

                                                                    Time Airway doctor/nurse Doctor / Nurse               Nurse (Scribe)

                                                                              Preparation           IV access               Document
                                                                          (drugs/equipments)                                All events
                                                                                                    Assist with
                                                                                                    preparation             Assist with
                                                                            Assess airway
                                                                                                    & drugs admin.          Monitor &
                                                                            Plan approach
                                                                                                                            preparation
                                                                            Preoxygenation
                                                                                                    Cricoid
                                                                                                    pressure
                                      Needle                                ETT placement

                                  Cricothyrotomy                                         Confirmation of ETT placement




           Emergency ETT intubation (RSI)                                   Emergency ETT intubation (RSI)
              The commonly used drugs                                               The commonly used drugs

                              Onset                                                                  Onset
 Drug           Dose; mg/kg
                              (Sec)
                                      Precaution/Contraindication    Drug             Dose; mg/kg    (Sec)   Precaution/Contraindication


Induction agents:                                                   Sedation/Analgesia:
                                                                    Midazolam           0.1-0.3      60-90      Long onset / no
Thiopental           3-5      10-15   Hypotension/ Porphyria
                                                                    Fentanyl (mcg/kg)     1-2        30-45      Chest wall rigidity / no
Propofol             1-2      10-15   Hypotension/Age< 2 yrs.
                                                                    Morphine             0.1-0.2     10-15      Long onset / no
Etomidate           0.2-0.6   10-15   Adrenal insufficiency/
                                                                    Pretreatment:
Ketamine             1-2      30-45       ICP / Head injury         Lidoocaine           1-1.5      3-5 min. Bradycardia / no




                                                                                                                                             8
12/15/2007




         Emergency ETT intubation (RSI)                                            Emergency ETT intubation (RSI)
               The commonly used drugs                                                  The commonly used drugs


                     Dose     Onset   Duration     Precaution/            Drug            Dose; mg/kg                Considerations
  Drug              (mg/kg)   (sec)    (min)       Contraindication
                                                                        Emergency drugs:
Muscle relaxants:
                                                                        Atropine               0.02                   Pediatric intubation
Succinylcholine      1-2       60     5-10       N-M disease /
                                                 Severe burn,
                                                 Hyperkalemia           Adrenaline                                    Standard resuscitation
                                                 Intra-ocular injury                       Incremental
                                                                                                                      cart in hand
                                                                                               dose
                                                                        Levophed                                      (emergency intubation)
Rocuronium        0.6-0.9     45-60   45-60                                                  to target
                                                                                                BP
                                                                        Metaraminol




                                                                                                  Can’t intubate              Seek HELP
                  The Emergency Difficult
                                                                       Ventilation effective
                     Airway Algorithm                                                                 ? Can ventilate

                                                                                                 Maintain Sellick’s
                                                                       Maintain oxygenation
                                                                                                 Reposition head             Unable to ventilate
                                                                             By BVM
                                                                                                  Use oral/nasal
                                                                       Reattempt intubation           airway
                                                                        by rescue devices
• Emergency airway management is different
• Emergency Airway Algorithm necessity                                 Maintain oxygenation                                 LMA / Combitube
                                                                             By BVM
• Prediction tools have limitations:
      • LEMON criteria cannot be universally applied                                              Emergency
                                                                       LMA / Combitube                                       Unable to ventilate
      • Consistent use will predict most of the difficult                                           Airway
                                                                       Maintain oxygenation        Algorithm
                                                                        Intubation through
                                                                               LMA                                                Cricothyrotomy
                                                                         Await expert help                                        Jet ventilation




                                                                                                           “ True success is not
                                                                                                                in the learning,
                                                                                                             But in it’s application
                                                                                                                to the mankind
                                                                                                                              F
                                                                                                                     F F               F
                                                                                                               F F                 F
                                                                                                                             F F




                                                                                                                                                     9

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RSI sheet-2007

  • 1. 12/15/2007 RSI in Emergency Department Rapid Sequence Intubation (RSI) Outline in Emergency Room • Indications for intubation • Considerations in Emergency intubation • Rapid Sequence Intubation (RSI) Siriporn Pitimana-aree, MD • The Failed Airway Dept. of Anesthesiology, • Defining the Difficult Airway Faculty of Medicine Siriraj hospital. • Rescue Devices (The Royal College of Anesthesiologists of Thailand) Indications for ETT intubation Emergency ETT intubation: Considerations • Time pressure • Absent or inadequate respiration • Unstable patient • Impending airway obstruction • Physiologic responses • Inability to protect airway • Possibly difficult situation • Uncooperative / combative • Not fasted • Difficult airway Emergency ETT intubation: Physiologic responses to intubation • Incidence of difficult & failed intubation: 8% •Gagging • Frequency of esophageal intubation: 8% •Rise in ICP 40% of these - difficult intubation almost all recognized by clinical criteria •Rise in BP but 3, decrease saturation detected by SpO2 •Tachycardia / Bradycardia • Incidence of pulmonary aspiration: 4% •Dysrhythmias • Hemodynamic consequences: 3% died during or within 30 min. of intubation 1
  • 2. 12/15/2007 Rapid Sequence Intubation (RSI) Rapid Sequence Intubation (RSI) Definition Definition Incorporates: The virtually simultaneous administration • Every patient has a full stomach of a potent sedative agent • Preoxygenation & a neuromuscular blocking agent • No interposed ventilations to induce unconsciousness • Sellick’s maneuver & motor paralysis for tracheal intubation. Rapid Sequence Intubation (RSI) Rapid Sequence Intubation (RSI) Contraindications: Advantages of RSI Anticipate of difficult airway& intubation •Minimizes risk of aspiration •Facilitate intubation Staff inexperienced in RSI •Blunt untoward physiologic responses •Avoid awake intubation Patients allergic or contraindication to drugs used in RSI Rapid Sequence Intubation (RSI) Rapid Sequence Intubation (RSI) The Six Ps of RSI 10 min The Sequence Preparation Preparation Preoxygenation Paralysis with Sedation Preoxygenation Protection Placement the time of administration of ………..Zero Postintubation care Succinylcholine. 2
  • 3. 12/15/2007 Rapid Sequence Intubation (RSI) Rapid Sequence Intubation (RSI) The Sequence …10 minutes ---- Zero The Sequence …5 minutes ---- Zero Preparation Preoxygenation • Assess airway difficulty (LEMON) • 100% oxygen for five minutes • Plan approach • 8 vital capacity breaths • Assemble drugs and equipments • Provides essential apnea time • Establish access • Apnea time varies • Establish monitoring Rapid Sequence Intubation (RSI) The Sequence Zero!! Paralysis with Sedation • Sedative / Induction agent IV push • Succinylcholine 1.5 mg/kg IV push Entering the red zone... Rapid Sequence Intubation (RSI) The Sequence …Zero + 30 seconds Protection • Sellick’s Maneuver • Position patient Optimal External Sellick’s maneuver • Do not bag unless SpO2 < 90% Laryngeal Manipulation (Cricoid pressure) (Backwards, Upwards, Rightwards Position (BURP) 3
  • 4. 12/15/2007 Rapid Sequence Intubation (RSI) The Sequence …Zero + 60 seconds Placement • Check mandible for flaccidity • Intubate, remove stylet • Confirm tube placement – EtCO2 • Release Sellick’s maneuver “ Sniffing position ” Rapid Sequence Intubation (RSI) The Sequence Experinced Inexperinced Postintubation care Auscultation 100% 68% •Ongoing sedation and/or paralysis ETCO2 100% 100% •Mechanical ventilation (if needed) Self inflating bulb 96% 98% •Further investigations (CXR, ABG) Trachlight 84% 87% •Postintubation hypotension Rapid Sequence Intubation (RSI) “Failed intubation” What do you do? If you can not intubate after RSI? Rescue Maneuvers • The first rescue from failed intubation is “Failed intubation” bagging. • The first rescue from failed bagging is better bagging. • Rescue devices 4
  • 5. 12/15/2007 The “Failed” Airway The “Failed” Airway • Multiple Definitions… Clinically, 2 types of “failed” airways: – Number of failed attempts (e.g., three) – Failure to ventilate with a BVM 1. Cannot intubate, but can oxygenate – Failure to oxygenate – Failure to visualize the larynx 2. Cannot intubate, and cannot oxygenate The Difficult Airway The Difficult Airway Identification of the Difficult Airway The DIFFICULT AIRWAY is something you 3 Key Attributes PREDICT… A FAILED AIRWAY is something you • Difficult Bag/Mask Ventilation EXPERIENCE!! • Difficult Intubation • Difficult Cricothyrotomy The Difficult Airway The Difficult Airway Difficult Bag Mask Ventilation Difficult Cricothyrotomy Mask seal Surgery scar Obesity Hematoma Aged (>55) Obesity No teeth Radiation Stiff lungs Tumor 5
  • 6. 12/15/2007 Predicting of difficult airway Difficult Intubation Identification of the Difficult Airway • A short bull neck • Prominent incisors • BMV as important as intubation • A receding chin • Mouth opening/access • Limited mouth opening • Neck extension at AOJ • Chin to hyoid distance • Neck flexion at CTJ < 6 cm (3FB) • Mentum-Hyoid-Thyroid distance • Potential C-spine injury • Presence/Risk of obstruction • Facial deformity • Morbid obesity Difficult Intubation Difficult Intubation Identification of the Difficult Airway Identification of the Difficult Airway The LEMON law L ook externally Development of a consistent approach: E valuate 3-3-2 M allampati The LEMON law O bstruction? N eck mobility © National Emergency Airway Management Course © National Emergency Airway Management Course Difficult Intubation Difficult Intubation Identification of the Difficult Airway Identification of the Difficult Airway L ook externally E valuate 3-3-2 - Difficult BMV (MOANS) - Difficult Cricothyrotomy (SHORT) Or some other thyromental - Intubator Gestalt distance equivalent 6
  • 7. 12/15/2007 Difficult Intubation Difficult Intubation Identification of the Difficult Airway Identification of the Difficult Airway M allampati O bstruction? Difficult Intubation Difficult Intubation Identification of the Difficult Airway Management of the Difficult Airway N eck mobility • Need a consistent approach • Awake techniques by default • Need definition of and preplanned approach to failed airway • No “one trick pony” approach • Alternative devices Difficult Intubation Management of the Difficult Airway • Alternative/Rescue devices? – Supraglottic: LMA, Combitube – Stylet, Gum elastic bougie; GEB – Lighted stylets: Trachlight, Lightwand – Fiberoptic devices: flexible, rigid, hand-held – Surgical: open, transtracheal 7
  • 8. 12/15/2007 L M A I n s e r t i o n Combitube I n s e r t i o n Emergency ETT intubation: Team members & their roles Time Airway doctor/nurse Doctor / Nurse Nurse (Scribe) Preparation IV access Document (drugs/equipments) All events Assist with preparation Assist with Assess airway & drugs admin. Monitor & Plan approach preparation Preoxygenation Cricoid pressure Needle ETT placement Cricothyrotomy Confirmation of ETT placement Emergency ETT intubation (RSI) Emergency ETT intubation (RSI) The commonly used drugs The commonly used drugs Onset Onset Drug Dose; mg/kg (Sec) Precaution/Contraindication Drug Dose; mg/kg (Sec) Precaution/Contraindication Induction agents: Sedation/Analgesia: Midazolam 0.1-0.3 60-90 Long onset / no Thiopental 3-5 10-15 Hypotension/ Porphyria Fentanyl (mcg/kg) 1-2 30-45 Chest wall rigidity / no Propofol 1-2 10-15 Hypotension/Age< 2 yrs. Morphine 0.1-0.2 10-15 Long onset / no Etomidate 0.2-0.6 10-15 Adrenal insufficiency/ Pretreatment: Ketamine 1-2 30-45 ICP / Head injury Lidoocaine 1-1.5 3-5 min. Bradycardia / no 8
  • 9. 12/15/2007 Emergency ETT intubation (RSI) Emergency ETT intubation (RSI) The commonly used drugs The commonly used drugs Dose Onset Duration Precaution/ Drug Dose; mg/kg Considerations Drug (mg/kg) (sec) (min) Contraindication Emergency drugs: Muscle relaxants: Atropine 0.02 Pediatric intubation Succinylcholine 1-2 60 5-10 N-M disease / Severe burn, Hyperkalemia Adrenaline Standard resuscitation Intra-ocular injury Incremental cart in hand dose Levophed (emergency intubation) Rocuronium 0.6-0.9 45-60 45-60 to target BP Metaraminol Can’t intubate Seek HELP The Emergency Difficult Ventilation effective Airway Algorithm ? Can ventilate Maintain Sellick’s Maintain oxygenation Reposition head Unable to ventilate By BVM Use oral/nasal Reattempt intubation airway by rescue devices • Emergency airway management is different • Emergency Airway Algorithm necessity Maintain oxygenation LMA / Combitube By BVM • Prediction tools have limitations: • LEMON criteria cannot be universally applied Emergency LMA / Combitube Unable to ventilate • Consistent use will predict most of the difficult Airway Maintain oxygenation Algorithm Intubation through LMA Cricothyrotomy Await expert help Jet ventilation “ True success is not in the learning, But in it’s application to the mankind F F F F F F F F F 9