A due diligence Annual progress report for the CLINCHEM Department (www.clinchem.kasralainy.edy.eg) An assessment tool for over all productivity and development of Education, Research and Laboratory healthcare services. Highlights: 1- Mission, Vision and objectives 2- Role of the Department 3- HR 4- Organogram for the year 5- Lab Services 6- Scientific Research 7- Projects and more

1. ANNUAL PROGRESS REPORT
Clinical & Chemical Pathology
Department
Reporting period: January 2010– December 2010
2010
Chair of the Department: Prof. Dr. Ahmed El-Saifi
El
Prepared by: Dr. Nelly Abulata
Lecturer of Clinical Pathology
1

2. Table of Contents
I. Letter from the Chair……………………………………………………………………………………3
II. ClinChem at a glance
1 About us …………………………………….……………………………………………..…….….4
2 Role of the Department………….…………………..………………………………..……….…...5
III. Human Resources……………………………………………………………………………..………6
IV. Organizational Chart………………………………..………….……………………………………....7
1 Deputies……………………………………………………………………………………….…..…..7
2 Advisory Group….…………………..……………………………………………………………...…7
3 Seniors of Each Division…………………………………….……………………………….. ..……..7
4 Secretary General for the Council of the ClinChem Department & Technical Development Officer......7
5 Executive Team…………………………………………………………………………………….....8
6 Executive committees……………………………………………………………………………..…11
V. Laboratory Services we provide…………………………………………..……………………..….....12
1 Background Information…………………………………..……………………………….………......12
2 Total Annual Productivity…………………………………..…………………………………………13
3 Productivity per Lab……………………………………………………………………………….....15
4 Productivity per division……………………………….…………………………………….……..…19
5. Blood Bank Services…………………………………………………………………………….…....19
VI. 2010 Activities & Accomplishments……………………………………..……………………….…20
1. Scientific Research …………………………...…………………………..…………...……………...20
2. Quality Assurance Committee for Laboratory Services……………………………………………….23
3. Quality Assurance Committee for Education………………………………………………………...24
4. ClinChem Conferences……………………………………………………………………………….24
5. Postgraduate Library updated………………………………………………………………………..29
6. Department Website Redesigned and Updated………………………………………………………30
2

3. I- LETTER FROM THE CHAIR:
My goals for the department during 2010 were to rejuvenate and modernize it. Working
together with more than 226 faculty members, nearly 30 residents and several hundred
Technologists & Technicians, nurses, administrators, and staff who make up the department, we
have made rapid strides toward achieving those goals. This year we achieved an overall annual
productivity of 4,958,016 tests which could not have been reached without our dedicated
manpower (944 employees).
With the appointment of new Heads of Laboratories, Heads of Units and Laboratory Directors and
with the creation of an Executive Committee, the Department now has the infrastructure it needs
to continue its trajectory. All through 2010, we continued a steady expansion in our three major
missions; Laboratory Services, Teaching & Training and Research Activities.
In the Laboratory service arena, we continued to push ahead with the implementation of Quality
Assurance System at Al– Manial Clinical Pathology Laboratory that has replaced our vulnerable
home grown system. The construction of both the new Laboratory at the New Maternity Hospital
& the New Emergency Hospital are among our top priorities and we anticipate moving into the
facility by mid 2011. Teaching activities also remained very strong & the Department's pre–
master & pre-doctorate training programs have been modified. In the Research arena, several
research projects were funded by the faculty under the roof of the the 2-5yr plan for the Research
activities of the Department which involved all 4 specialties of the Department (Hematology,
Immunology, Microbiology and Chemistry. As for our international publications, over 20 articles
were published by our faculty, several of which were in the high impact journals.
Another source of pride for me and for the department as a whole was that the Department held 2
very successful Scientific Conferences; 1st Annual Scientific Conference “CLINCHEM 2010”
nd
from 31 March -2 April with the theme Molecular Biology into the Future & a 2 CLINCHEM 2010
th
“Transfusion & Quality updates; Revolution not evolution” on the 24 of October. The Department
is building on an extraordinary legacy and has great potential and we plan to make it a yearly
event
In summary, the Department is on the right path and we look forward to further progress. We
hope that in collaboration with our colleagues in the Faculty and Hospital we can upgrade our
research, teaching and clinical enterprise in a fashion that melds with the programmatic directions
of the University as a whole.
Prof. Ahmed El-Saifi
Chair, Clinical and Chemical Pathology
Department
3

4. II- CLINCHEM AT A GLANCE:
1-
ABOUT US
Mission
“Is to provide excellence in Laboratory services, Teaching, Training and Research
activities”.
Vision
We aspire to be recognized as an Academic Department of excellence to support and
enhance the mission and vision of Kasr Al-Ainy Faculty of Medicine, Cairo University.
Objectives
1. To provide excellent laboratory medicine services for the patients of Kasr Al-Ainy
Hospital in a timely & professional manner.
2. To provide an atmosphere of respect for our staff while encouraging continued
personal growth, education and development.
3. To provide excellent teaching to a broad spectrum of health care professionals,
health care workers and Lab personnel in conjunction with The University.
4. To provide the physical facilities and atmosphere where research activities can
flourish, in collaboration with Kasr Al-Ainy Faculty of Medicine and other affiliated
institutions.
5. To promote health, treatment and prevention of disease in the diverse population
which we serve.
4

5. 2- ROLE OF THE DEPARTMENT
Laboratory
Services
Teaching &
Research
Training
1. Laboratory services:
The Department offers Clinical and Chemical Laboratory services designed to meet the
needs of physicians, & patients. The Department has 2 Main Labs at Al
Al-Manial Hospital,
a Lab. in each of the following Hospitals; the Specialized Hospital (4th Floor), the
Internal Medicine Hospital, the Pediatric Japanese Hospital , the Pediatric Abou Elrish
Hospital, King Fahd Hospital, the French Hospital in addition to Emergency Labs that
ahd
offer the Lab services during the evening and night shifts. The Department is also
responsible for the Technical supervision of the Blood Bank.
2. Teaching & Training:
The Department is committed to providing strong and balanced Teaching and Training
nt
programs mainly to Postgraduate students, principally in the Master and Doctorate
degrees in Clinical and Chemical Pathology tailored to each student subspecialty
Chemical
(Hematology, Immunology, Microbiology or Chemical Pathology). The Department is
Immunolog
.
also partly involved in the Teaching & Training of postgraduate students of other
Departments enrolled in Master, Diplomas & Doctorate degrees in addition it provides
instructional courses to the 6th year students.
6t
3. Research activities:
The Research Faculty members within the Department are nationally recognized. The
Research ranges from clinical to basic Research, with an emphasis on Hematologic
Malignancies, Virology & Molecular Genetics.
5

6. III. HUMAN RESOURCES
The Department has a total manpower of around 944 employees. This comprises:
· 287 Doctors ; 226 Faculty members, 36 Specialists & 27 Residents
· 369 Technologists & Technicians
· 59 Nurses
· 131 Administration
· 96 Cleaners
Doctors
27
36
Faculty staff
Specialists
Residents
226
Human Resources
400
369
350
300
290
250
200
Doctors
131
150
96
100
59
Technologists & Technicians
Nurses
50
Administration
0
Cleaners
6

7. IV- ORGANIZATIONAL CHART
The Organizational structure has been modified and effective teams have been built
aiming to introduce the “we” culture and a more qualitative workplace.
1. Deputies:
Chair of the Clinical & Chemical Pathology
Dept
Deputy for
Scientific
Research
Affairs
Team with
representatives of
all specialties
Deputy for
Teaching,
Training Staff
Positioning &
relocation
Affairs
Team with
representatives of
all specialties
Deputy for
Examination
Affairs
Team with
representatives of
all specialties
1. A Deputy for Scientific Research Development Affairs: (Prof. Dr. Ali Shams ElDin)
Who is in charge of the overall management for planning and coordinating multiple research
teams and development activities and processes at a research and development unit/group level
that will eventually lead to the international recognition of our Department that will in turn
participate in the International recognition of the of Kasr Al Ainy Faculty of Medicine. This Deputy
Al-Ainy
together with a team of representatives of each specialty is responsible for the validation of all the
resentatives
MSc & MD protocols before they are officially registered.
2. A Deputy for Teaching, Training & staff relocation: (Prof. Dr. Azza Mostafa)
Who is in charge of managing the teaching & training package that encompasses both these
encom
elements in order to maintain a motivated and skilled workforce and to fulfill the needs of the
organization. This Deputy is also in charge of the relocation of staff to & from labs according to
is
the need.
3. A Deputy for Examination Affairs: (Prof. Dr. Safaa Al-Karaksy)
A
Who is in charge of managing and liaising with the heads of the units all the matters related to
the examinations including schedules, exam development & examination boards formation.
7

8. 2. Advisory Group
The Advisors are composed and structured in order to provide non-binding but
informative guidance to the Chair that serves as an ally during discussions when needed.
The advisory group includes:
· Prof. Dr. Omnia Yousef: Emeritus Prof. of Chemical Pathology
· Prof. Dr. Souhair Helal: Emeritus Prof. of Clinical Pathology: subspecialty Microbiology
· Prof. Dr. Naguib Zohair: Prof. of Clinical Pathology: subspecialty Hematology
3. Seniors of each Division
The Department has 4 specialties and accordingly 4 seniors:
· Prof. Dr. Safaa Al-Karaksy: Senior Immunologist
· Prof. Dr. Tayssir Eyada: Senior Hematologist
· Prof. Dr. Amani El-Kholy: Senior Microbiologist
· Prof. Dr. Fatma El-Mougy: Senior Chemical Pathologist
4. Secretary General for the Council of the ClinChem Department
& Technical Development Officer (Dr. Nelly Abulata)
As the Secretary General of the Council she moderates the Council and several Departmental
Committees. And as the Technical Development Officer she collaborates with Laboratory
Managers, Heads of Laboratories, Heads of Units and other Project Managers in the restructuring
of the organizational system, developing decentralization and defining job responsibilities within
the Department aiming to ensure that the objectives and performance plans of the Department
and Faculty were being met
;
5. Executive team
Is composed of the Laboratory Directors (Administrative affairs), the Heads of Labs &
Heads of Units (Technical Affairs) that direct, supervise and coordinate the functions and
activities of the Hospital laboratories
8

9. Main Lab at Manial Hospital
Laboratory
Head of
Lab.
(Technical)
Lab Director
(Administrative)
Head of
Hematology
Unit
Head of
Immunology
Unit
Head of
Genetics
unit
Head of
the
Molecular
Unit
Head of
Microbiology
Unit
Manial
Clinical
Pathology
Lab.
Prof. Safa
Al-Karaksy
Prof. Dr. Mona
Salah
Prof. Dr.
Nabil ElDanasoury
Prof. Dr.
Safaa AlKaraksy
Prof. Dr.
Hala
Farawela
Prof. Dr.
Mona
Salah
A. Prof. Dr.
Nada Nawar
Laboratory
Head of Lab.
(Technical)
Lab Director
(Administrative)
Head of
Trace
Elements
Unit
Head of
Chemistry
Routine Unit
Head
of Proteins
Unit
Manial
Chemical
Pathology
Lab.
Prof. Dr.
Fatma ElMougy
Prof. Dr.
Badawy AlKhouly
Prof. Dr.
Badawy AlKhouly
Prof. Dr.
Lamia
Mansour
Prof. Dr.
Sahar
Abdel-Atty
9
Head
of Hormones
Unit
Prof. Dr.
Nadida
Gohar

10. Other Hospital based labs
Laboratory
Head of
Lab.
(Technical)
Lab Director
(Administrative)
Head of
Hematology
Head of
Immunology
Head of
Microbiology
Head of
Chemical
Pathology
Internal
Medicine
Hospital
Lab.
Japanese
Hospital
Lab.
Prof. Dr.
Laila
Hegazy
Dr. Magda Negm
Prof. Dr.
Laila Hegazy
A .Prof Dr.
Nancy ElGuindy
Prof. Dr.
Hanaa
Arnaout
TBD
Prof. Dr.
Hanaa
Arnaout
Dr. Safa
Meshal
Abou-Elrish
Mounira
Hospital
Lab.
Prof. Dr.
Iman ElMahgoub
Prof. Dr. Nesrine
El-Gharabawy
Prof. Dr.
Nesrine ElGharabawy
Specialized
Hospital
th
Lab. (4
floor)
French
Hospital
Lab.
Prof. Dr.
Tayseer
Eyada
Dr. Sheriene
Abdel-Kader
Prof. Dr.
Tayseer
Eyada
Prof. Dr.
Sheriene
Mahmoud
Prof. Dr.
Souhair Helal
Prof. Dr.
Sahar
Abdel Atty
Prof. Dr.
Azza
Mostafa
Dr. Hanan
Ibrahim
Prof. Dr.
Naguib
Zoheir
Prof. Dr.
Tagreed
Gaafar
Prof. Dr.
Amani El
Kholy
Prof. Dr.
Ola ElSissy
King Fahd
Hospital
Lab.
Psychiatric
Hospital
Lab.
New ER
Hospital Lab
Maternity
Hospital
Lab.
Sharm
ElSheikh Int.
Hosp.
Prof. Dr. Hala Sheebah
Blood Bank
Prof. Dr.
Mervat AlAnsary
A. Prof. Dr.
Hany
Hussein
A.Prof. Dr.
Mona Mohie
El-Din
Prof. Dr. Maha
Gaafar
Prof. Dr.
Amal
Abdel
Wahab
Prof. Dr.
Heba
Sharaf ElDin
Prof. Dr. Badawy Al-Khouly
Prof. Dr. Badawy Al-Khouly
A. Prof. Dr.
Assistant Prof.
TBD
Iman
Aya Nassef
Mandour
Assistant Prof. Mohamed Shehata
Dr. Abeer Reehan
10
TBD
A. Prof. Dr.
Iman
Mandour

11. 6. Executive Committees
1. Executive Committee for Laboratory Affairs:
As things evolved over time, we found that it was necessary to form an Executive Committee,
which has been meeting every month for the past couple of months usually one week prior to the
Board meeting of the Department. At those meetings, the Executive Committee reviews the major
issues facing the Department, weighing pros and cons and making preliminary decisions, to be
ratified by the Board as a whole at the actual Board meeting of the Department. The Committee is
comprised of:
1. The Chair of the Department: Prof. Ahmed El-Saifi
2. The Head of the Laboratories
· Prof. Azza Mostafa
· Prof. Safaa Al-Karaksy
· Prof. Mervat Al-Ansary
· Prof. Tayssir Eyada
· Prof. Fatma El-Mougy
· Prof. Hanaa Arnaout
· Prof. Laila Hegazy
· Prof. Eman ElMahgoub
· Prof. Hala Sheebah
3. The Laboratory Directors
· Prof. Badawy Al-Kholy
· Prof. Mona Salah
· Prof. Nesrine ElGarabawy
· Ass. Prof. Lobna ElMessery
· Dr. Magda Negm
· Dr. Abeer Reehan
· Dr. Sherine Abdel-Kadr
4. Other members:
· Prof. Sherief Naseh Amin (Deputy Head of the General Hospitals)
· Prof. Amani Al-Kholy (Most Senior Microbiologist)
· Prof. Omnia Youssef (Advisory Group member)
· Prof. Souhair Helal (Advisory Group member)
2. Executive Committee for Blood Bank Affairs:
Since the Department is responsible for the Technical supervision of the Blood Bank an
Executive Committee for the Blood Bank has also been formed which will review and discuss any
issues facing the Blood Bank. The Committee will start meeting on monthly basis starting from
next month, typically one week prior to the Hospital Board meeting. The Committee is comprised
of:
1. The Chair of the Department (Prof. Ahmed El-Saifi)
2. The Head of the Blood bank (Prof. Mervat Al-Ansary)
3. The Blood Bank Director (Dr. Abeer Reehan)
4. The Deputy Head of the General Hospitals (Prof. Sherief Naseh Amin)
5. Other members (to be determined).
11

12. V- LABORATORY SERVICES WE PROVIDE
1. Background information:
Our Laboratories provide an extensive menu of routine & specialized laboratory tests to the
patients who seek care at Kasr Al-Ainy Hospitals.
Lab Divisions
· Hematology Laboratory
· Clinical Immunology & Molecular Diagnostics
· Clinical Microbiology
· Clinical Chemistry
12

13. 2. Annual Productivity:
Hospital
Lab
Relevant Hospital Info
Total
Annual
Inpatient
beds
Average
Outpatients
clinic cases
per month
Average
ER cases
per month
Lab
Productivity
% out of the
total
annual
Productivity of
all labs
Manial
Labs
2,018
40,980
15,067
1804809
37%
Japanese Lab
421
8700
4,876
553410
11%
Abou El-Rish
Lab
307
23,477
8,539
473044
10%
Internal
Medicine
Lab.
357
2175
1,268
553298
11%
4th floor Lab
277
No Clinic
180
268033
6%
King Fahd Lab 111
514
No ER
134430
3%
French
Lab
Not
available
Not
available
1070644
22%
1,200
13

14. % out of the total annual productivity of
2010
6%
3%
Manial
10%
French
37%
Internal Medicine
Japanese
11%
Abou ElRish
4th floor
King Fahd
11%
22%
2010 Annual productivity
6000000
Total no. of tests & Doctors
4,958,016
5000000
4000000
3000000
2000000
1000000
(130)
1,804,809
(47)
1,070,644 (30)
(21)
(33)
553,410 553,298 473,044
0
Laboratory
14
(24)
(2)
268,033 134,430
(10)
50,174

15. 3. Productivity per Lab
1. Al-Manial Clinical & Chemical Pathology Labs:
We have 2 labs at Al-Manial Hospitals one on the ground floor (Clinical Pathology) and one on
the 2nd floor (Chemical Pathology) with a total no. of employees of 328.
The Clinical Pathology Laboratory employs 169 people; 57 Faculty Staff (17 Emeritus
Professors, 13 Professor, 2 Assistant Professors , 7 Lecturers, 6 Assistant Lecturer & 5
Demonstrators), 5 Specialists, 5 Residents, 14 Technologists, 47 Technicians, 6 Nurses, 20
Administration & 15 Cleaners.
The Chemical Pathology Laboratory employs 159 people; 61 Faculty Staff (10 Emeritus
Professors, 11 Professor, 8 Assistant Professors , 12 Lecturers, 17 Assistant Lecturer & 3
Demonstrators), , 3 Residents, 14 Technologists, 56 Technicians, 4 Administration & 16
Cleaners.
Manial Labs
2000000
1800000
1600000
1400000
1200000
1000000
800000
600000
400000
200000
0
1804809
1381567
Hematology
Immunology
Microbiology
369530
Parasitology
Chemical Pathology
37402
15571
739
15
Total

16. 2. Japanese Lab:
The Laboratory employs 83 people; 25 Faculty Staff (8 Professor, 6 Assistant Professors, 4
Lecturers & 7 Assistant Lecturer), 5 Residents, 1 Technologists, 39 Technicians, 13
Administration & 5 Cleaners.
Japanese Lab
600000
500000
400000
300000
200000
100000
0
533410
393953
Hematology
Immunology
120205
13665
Microbiology
13305
12283
Parasitology
Chemical Pathology
Total
3. Abou El-Rish Lab:
The Laboratory employs 67 people; 18 Faculty Staff (5 Professor, 3 Assistant Professors , 6
Lecturers, 3 Assistant Lecturer & 1 Demonstrators), 10 Specialists, 5 Residents, 9
Technologists, 15 Technicians, 9 Administration, 2 Nurses & 6 Cleaner
Abou ElRish ElMounira Lab
500000
450000
400000
350000
300000
250000
200000
150000
100000
50000
0
473044
320064
Hematology
Immunology
103166
12594
21993
15227
Microbiology
Parasitology
Chemical Pathology
Total
16

17. 4. Internal Medicine Lab:
The Laboratory employs 42 people; 14 Faculty Staff (3 Emeritus Professor, 3 Professor, 1
Assistant Professors , 3 Lecturers & 5 Assistant Lecturer), 2 Specialists, 5 Residents, 10
Technologists, 6 Technicians, 4 Administration & 2 Cleaners.
Internal Medicine Lab
600000
500000
400000
300000
200000
100000
0
490319
553298
Hematology
Immunology
55335
3220
1029
Microbiology
3125
Parasitology
Chemical Pathology
Total
5. 4th floor Lab:
The Laboratory employs 53 people; 11 Faculty Staff (1 Emeritus Professors, 5 Professor , 2
Assistant Professors, 3 Lecturers), 3 Specialists, 10 Resident Specialists, 8 Technologists, 10
Technicians, 9 Administration, 4 Nurses & 6 Cleaners.
4th floor Lab
300000
250000
200000
150000
100000
50000
0
268033
216960
Hematology
40057
Immunology
4929
3660
3327
Microbiology
Parasitology
Chemical Pathology
Total
17

18. 6. King Fahd Lab:
The Laboratory employs 21 people; 1 Faculty Staff (1 Professors), 1 Specialists, 7
Technologists, 5 Technicians, 5 Nurses, 1 Administrative Secretaries & 1 Cleaner.
King Fahd Lab
160000
140000
120000
100000
80000
60000
40000
20000
0
134430
92325
Hematology
24692
Immunology
9837
2513
5055
Microbiology
Parasitology
Chemical Pathology
Total
7. French Lab
The Laboratory employs 223 people; 45 Faculty Staff (4 Emeritus Professor, 11 Professor,
11 Assistant Professors, 13 Lecturers, 4 Assistant Lecturer), 2 Senior Registrars, 17
Technologists, 73 Technicians, 7 Nurses, 56 Administration & 23 Cleaners
French Lab
1800000
1600000
1400000
1200000
1000000
800000
600000
400000
200000
0
1714242
1480068
Hematology
Immunology
159464
37317 18285 19108
Microbiology
Parasitology
Chemical Pathology
Total
18

19. 4. Productivity per division
16%
2%
Hematology
1%
Immunology
Microbiology
Chemical Pathology
81%
5. Blood Bank Services
· Blood Bank Profile: The Blood Bank employees approximately 128 people who are
involved in Blood Donation, Blood Processing and Hemapheresis.
· Blood Bank Structure:
• The Head of the Blood Bank: Prof. Dr. Mervat Al-Ansary
• Administrative Director: Dr. Abeer Reehan.
• The Team includes: 7 Specialists , 2 Residents, 6 Financial officers , 2 Administrative
Officers, 2 Social Officers, 1 Statistician, 5 Technologists, 30 Technicians, 35 Nurses, 7
Administrative Secretaries, 11 Clerks, 22 Cleaners
. 2010
Blood Bank services
Total
Outpatientclinic
Donation
campaign
Total
Rejected
Screened
HbsAg
HCV
HIV
Syphilis
Plasma
Cryo
20099
218
19878
325
1098
31
57
14387
3523
30075
50174
917
1135
29140
49018
252
577
928
2026
49
80
65
122
25640
40027
-----3523
19

20. VI- 2010 ACTIVITIES & ACCOMPLISHMENTS
1- Scientific Research
· Project Profile:
The aim of this project is to develop a plan for the Research activities of the Department over the
coming 2-5 yrs which will involve all the specialties of the Department. The project will hopefully
lead to the international recognition of the Department that will in turn participate in the
International recognition of Kasr Al-Ainy Faculty of Medicine
. Project starting date: 27/08/09
· Project structure:
Project Leader: Prof. Ali Shams El-Din
Project Team Members: Prof. Azza Mostafa, Prof. Taghrid Gaafar, Prof. Amani El-Kholy, Prof.
Fatma El-Mougy, Prof. Mona Wasif, Prof. Hala Farawela, Prof. Afaf ElBannah, Prof. Iman
Mansour, Prof. Hala Ali, Prof. Hala Gabr, Prof. Sahar Abdel Atty
Ethical committee Members: Prof. Azza Mostafa, Prof. Dr. Safaa Al-Karaksy, Prof. Amani ElKholy, Prof. Fatma El-Mougy
Key research subjects
1. HCV
2. Stem Cell Research
3. Neurodegenerative diseases
4. Infection prevention and control
5. Molecular basis of Hematological disorders
6. Juvenile Diabetes Mellitus.
. Accomplishments to date:
1. Planning process: Done
2. Implementation: Done
3. Follow: in process
. Research Grants:
1. STDF grant: "Stem Cell Therapy in Endstage liver cell failure".
Principle investigator: Prof. Dr. Hala Gabr
2. Cairo University Grant: "Isolation and identification of Limbal
Stem Cells". Co-investigator Prof. Dr. Hala Gabr
. Research Awards:
1. A. Prof Heba Abdel Razik has won the Award “
‫ةا و ا‬
”
2. Prof. Dr.Hala Gabr won the “University Award for the High impact factor award”
3. Dr. Dina Ahmed Mehaney has been awarded “Best MD thesis in Cairo University”
20

21. . Several projects received funding from the Faculty among which
are:
(>200,000LE)
1. Telomerase activity and hTERT mRNA expression in lymphoid leukemias (Shahira kamal,
Sarah Adel) Fund value 38,900LE
2. Detection of IL18 and its m-RNA expression in idiopathic thrombocytopenic purpura (Iman
Abdel Mohsen) Fund value 36,000 LE
3. Human brain and acute leukemia cytoplasmic (BAALC)gene andETS related genes (ERG)
expression in acute myeloid leukemia (Amal Soliman Nasr) Fund value:14,400L.E
4. 6q aberrations in lymphoproliferative disorders (Dalia Gamil) Fund value:26,237LE
5. Expression of TSC1 and TSC2 gene in the newly diagnosed acute leukemia (Zeinab Ali)
Fund value43.580
6. Study of the telomerase enzyme mutation in Acquired Aplastic Anemia in Egyptian children
(Prof. Dr. Mervat Al-Ansary, Prof. Dr. Amal El-Beshlawy, Prof Dr.Mona El Tagui.Assistant,
Prof. Dr. Mona Hamdy, Dr. Nelly Abulata, Dr. Fadwa Saeed) Fund value: 21,800
7. Genetic Polymorphism of Oxidative stress genes and the risk of non-Hodgkin’s Lymphoma
and its relevance to HCV infections (Prof. Dr. Hala Farawela, Prof. Dr. Hamdy ElZawam,
Prof. Dr. Somia Abdel Rahmna, A. Prof. Aya Nassef, A.Prof. Mervat Khorshied, A.Prof. Heba
Gouda, Dr. Iman Shaheen, Dr. Nelly Abulata) Fund value 21, 790 LE
8. Prognostic relevance of pSTAT5 expression in acute myeloid Leukemia (A. Prof. Heba
Hassan Abou Elewa) Fund value13,140 L.E.
9. Study of ex-vivo expanded bone marrow mesenchymal stem cells in aplastic anemia patients
and the role of transcriptional factor gata-2 in fatty marrow replacement (A. Prof. Doha Abdel
Hamid) Fund value 20,765 L.E.
. International publications
1-Association Between The Monocyte Chemoattractant Protein-1 (MCP-1) 2518G/A Gene
Polymorphism And Acute Myocardial Infarction Patients Among Egyptian Population. (El
Mahgoub, Iman R; Afify, Reham A; Aal, Asmaa A Abdel; Beda, Dalia) . Coagulation Fibrinolysis J
2- Study of the Association of CYP2D6*4 Polymorphism with the Risk of Chronic Myeloid
Leukemia (Sahar K Hussein, Asmaa A Abd El-Aal, Reham A. Aleem Afify) Journal of infection
control.
3- AnnexinV and adhesion molecules expressions on erythrocytes in sickle cell anemia
patients treated with hydroxyurea (Nermeen el Desoukey, Hend el Sherbiny, Dalia G. Amin)
The Arab journal of laboratory medicine
4- Clinical relevance of angiopoietin-1, angiopoietin-2, and their receptor Tie-2expression
in acute myeloid leukemia (Safaa M. El Karaksy . Nancy M. El Guindy . Heba M. Gouda .
21

22. Mervat M. Khorshied . Iman A. Shaheen . Reham E. Abu Khalil . Noha Y. Ibrahim. Comparative
Clinical Pathology
5-The
clinical
significance
of
methylenetetrahydrofolate reductase (MTHFR)
polymorphisms in acute lymphoblastic leukemia (Hanaa H. Arnaout . Mervat M. Khorshied,
Iman A. Shaheen . Heba M. Gouda . Noha Y. Ibrahim . Naglaa F. Koura.) . Comparative Clinical
Pathology
6- Portal vein thrombosis and haematemesis in chronic liver disease. Are P-selectin and
PSGL-1 clues? (Hoda A. Sadek , Bothina A. Madkour , Salwa M. Toima , Abeya F. Saleh , Iman
A. Shaheen ,Rabab F. Yaseen, Emad El-Din A. Bayoumi) Arab Journal of Gastroentrology
7-The osteogenic differentiation potentials of umbilical cord blood haematopoietic stem
cells. Mervat M. Khorshied ; Heba M. Gouda ; Iman A. Shaheen Tarek N. Al Bolkeny.
Comparative Clinical Pathology.
8-Identification and clinical evaluation of the receptor for Hyal-uronic acid mediated
motility (RHAMM/CD 168) in AML patients: Khorshied M., Omar D. Pan Arab Journal of
Oncology
9- Nucleophosmin gene mutation in acute myeloid leukemia patients. Khorshied MM, Said
WA, Shaaban HA. Saudi Med J
10- Autologous melanocyte–keratinocyte suspension in the treatment of vitiligo. BM ElZawahry, NS Zaki, DA Bassiouny, RM Sobhi, A Zaghloul, MM Khorshied and HM Gouda.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY.
11- Detection of CXCL12 Gene Polymorphism and CXCR4 Expression in Egyptian Acute
Myeloid Leukemia Patients (Aisha Abd El-Rahman, Samah Abdel-Hamid, Manal Makhlouf,
Nermine El-Desouky, Mohamed Al-Feky and Sherif Yousri. The Journal of American Science
12-Detection of XRCC1 gene Polymorphisms in Egyptian Patients with Acute Myeloid
Leukemia(Mona Salah El-Din, Hanan Raslan, Samah Abdel-Hamid, Manal Makhlouf)
Comparative Clinical Pathology
13- Mesenchymal Stem Cell (MSC) Transfusion as a Novel Immunosuppressive Regimen
with Possible Induction of Microchimerism. (Gamal Saadi, Mervat El-Ansary, Samah Abd ElHamid, Eman Abd EL-Aziz) Global Science of Books 4(2).
14- Dendritic Cell Vaccine as an Adjuvant Therapy in the Treatment of Chronic Myeloid
Leukemia. Mervat El-Ansary, Mervat Mattar, Shereen Kamel, Samah Abd El-Hamid, Rania Abou
Elnour Global Science of Books 4(2
15- Phase I Trial: Mesenchymal Stem Cells Transplantation in End Stage Liver Disease.M
El-Ansary, Sh Mogawer, I Abdel-Aziz, S Abdel-Hamid. Journal of American Science. 6(12):135144
16- Cytogenetic study of the effect of Schistosoma mansoni infection on human peripheral
blood lymphocytes and the role of B-carotene and vitamin E in modulating this effect
.Mervat El Ansary, Iman Khaled, Abeya Fouad, Ola Mahmoud, Emad Baioumi, Heba Abo Bakr.
Journal of American Science.
22

23. 17- Celiac Disease in Children and Adolescents with Autoimmune Hepatitis : a Single –
centre Experience .Mortada El-shabrawi ,Hanna El-Karasy,Nabil Mohsen ,Mona Isa
,Mohammed Al-Biltagi , Mervat El-Ansari . Journal of Tropical Pediatrics Advance Access
18- Flow cytometric detection of leukemic stem cells (LSCs) in Egyptian pediatric B-acute
lymphoblastic leukemia (Manal W. El-Masry & Mervat M. Khorshied & Iman A. Shaheen & Nelly
N. Abulata & Tarek A. Hashem) Comparative Clinical Pathology
19- Case Control Series of Intrathecal Autologous Bone Marrow Mesenchymal Stem Cell
Therapy for Chronic Spinal Cord Injury. Nirmeen A. Kishk, Hala Gabr, Sherif Hamdy,Lamia
Afifi , Noha Abokresha, Hayam Mahmoud,Ahmed Wafaie, and Dalia Bilal. Neurorehabil Neural
Repair July 26, 2010. DOI: 10.1177/1545968310369801
20- Feasibility, Safety, and Efficacy of Directly Transplanting Autologous Adult Bone
Marrow Stem Cells in Patients With Chronic Traumatic Dorsal Cord Injury. A Pilot Clinical
Study. Osama S. Abdelaziz, Ahmed Marie, Mohamed Abbas, Mohamed Ibrahim, and Hala Gabr.
Neurosurg Q 2010;20:216–226.
21- Autologous Mesenchymal Stem Cells for Neuro-Regeneration After Traumatic Spinal
Cord Injury: A Comparison Between Bone Marrow and Peripheral Blood Populations. Abo ElKheir W, Gabr H, Awad MR, von Wild K, and Ramadan M. American Journal of Neuroprotection
and Neuroregeneration Vol. 2, 1–8, 2010 IF: 6.2 & received the University Award for the High
impact factor award
2- Quality Assurance for Laboratory service
. Project profile:
The aim of Quality assurance project (QA) is to ensure that the Laboratories of Cairo University
Hospitals provide services that meet the best quality standards.
. Project starting date: 27/08/09
. Project Structure:
Project Leader: Dr. Ola Khashaba
Project Team Leaders (2009/2010) : Prof. Safaa Al-Karaksy (Immunology), Prof. Naguib
Zoheir (Hematology), Prof. Mona Wasif (Microbiology),Prof. Lamiaa Mansour (Chemical
Pathology)
Project Team Members: Relevant staff members in each team.
. Accomplishments during 2009/ 2010 at Main Laboratories
(Al-Manial Clinical Pathology Lab., N.B. Chemical Pathology Lab. joined the project late by
mid -year 2010)
1. Initial assessment & Gap analysis in Al-Manial Lab using prepared checklists: Generic &
specific
23

24. 2. Team building
3. Awareness & Training sessions: For doctors and technicians
4. Development of standardized forms to be used in all departments including: Q.C,
Calibration, Maintenance, Temperature control, Refrigerator content and maintenance
card; in addition to special forms for some procedures e.g. ELISA, manual procedures,
and Cytochemistry.
5. Implementation of the developed forms in all relevant previously mentioned departments
with varying degree of compliance according to the results of the internal audits
performed by the project leader and the submitted audit reports.
6. Two formal announced internal audits were performed one on March 2010 and the
second on June 2010 (which included the Chemical Pathology lab.).Additional random
audits were performed through informal communication with the process owners as one
way of improving their performance.
7. Work is in progress to fully implement the Intranet through which the quality control will
be automated.
8. Work is in progress to teach doctors in charge of developing and interpreting the control
charts (or just how to read them after automation) and using the Westgard rules.
9. Training sessions and meeting with the new teams were regained by the end of the year
2010.
3- Quality Assurance for Education
· Project Profile:
The aim of this project is to check how well the Department meets it’s responsibilities, identifies
good practice and makes recommendations for improvement.
. Project starting date: 1/10/10
· Project structure:
Project Leader: Prof. Hala Sheebah
Project Coordinator: A. Prof Mervat Khorshied
Project Team Members: Prof. Hala Ali, Prof. Nehad Mosaad, A.Prof. Maha Gaafar, A.Prof. Aya
Nassef, A. Prof Mervat Khorshied, Dr. Safa Meshaal, Dr. Rania Darwish, Dr. Safaa ElGabarty
. Accomplishments to date:
1.
2.
3.
4.
5.
6.
Authentification of all the committees within the department
Gathering available & preparing unavailable job description for all the types of jobs & roles
Following up on the efficiency of teaching & training via evaluation surveys.
Maintaining the system & following up on complaints
Listing of the no. registered master & doctorate thesis’s
Listing of the no. of the number of projects that have received funding from the faculty.
24

25. 4- Training courses/ workshops:
•
Training course for “Screening metabolic disorders by Tandem Mass Spectrometry”
Organized via a collaboration between the Chemical Pathology team (Prof. Dr. Fayza A
Hassan Prof. Dr. Fatma El-Mougy Prof. Dr. Sahar Abdel-Atty Prof. Dr. Iman Mandour A.
Prof.Dr. Marian Morgan Dr. Dina Mehaney Dr. Mohammed A. Monem) and the Pediatric
Endocrinology team at Pediatric Hospital
•
Workshop in collaboration with ESPCR lead by Prof. Dr. Hala Gabr on: " Isolation,
characterization and tagging of Adipose-derived stem cells“
•
2 workshops Lead Prof. Amani Al-Kholy & her Team ( A.Prof. Mervat Gaber Al-Anainy,
A.Prof. Mona Mohieddin Abdel Halim, Dr. Mariam Adel, A. Lecturer Mai Sherief) in
collaboration with NAMRU-3 & USA-CDC:
1. Survey of antimicrobial consumption in Cairo Univ Hospitals
2. Use of PDA in Clinical surveillance for healthcare associated infections in ICUs
•
Workshop on “Molecular Diagnosis of Acute Respiratory infections”; lead by Prof. Amani AlKholy, Prof. Mona Salah, A. Prof. Iman AbdelRahman in collaboration with NAMRU-3
4- ClinChem Conferences
The Department held 2 very successful Scientific Conferences; the 1st CLINCHEM 2010
Conference" Molecular Biology: Into the future" held from 31st of March -2nd of April at
CICC had a record-breaking attendance of nearly 600 participants in the could not have been
achieved without the support of sponsors like SIEMENS,EL-DAWLEYA,TECHNOSCIEN,
CLINILAB,ETICO,ENDOMEDIX&ULTRADIAGNOSTICS.
In response to the feedback we received from our attendees and sponsors we decided to launch
the 2nd CLINCHEM 2010 Conference "Transfusion Medicine & Quality updates: Revolution
not evolution" that was held on the 24th of October, 2010 at the Learning Resources center at
Kasr Al-Ainy Faculty of Medicine, Cairo University which was another great success thanks to
sponsors such as DIA MED, FUTURE HORIZON, SPECTRA, SIEMENS & INTERPHARM.
Our goals for the Conferences were simple, but bold: to bring together successful Laboratory
Medicine professionals, Clinicians, Scientific and Medical publishers and Biotechnology
companies, to discuss opportunities and challenges in the exciting field of Genetics & Tissue
Engineering, by doing so, share the most up-to-date strategies explore recent developments and
identify fruitful avenues for further research to enhance the Quality of our Healthcare Services.
25

26. 1st ClinChem Conference 2010
“Molecular Biology: Into the future": 31st of March -2nd of April at
Cairo International Conference Center
General info
Conference President
Prof. Ahmed El-Saifi
Vice President
Prof. Azza Mostafa
Secretary General
Prof. Fatma El-Mougy
Dr. Nelly Abulata
Conference Coordinator
·
Organizing Committee
A. Prof. Mervat Gaber
A. Prof. Noha Shaheen
Dr. Mervat Khorshied
Dr. Nelly Abulata
Dr. Heba El-Baz
Dr. Riham El-Sayed
Prof. Omnia Youssef
Prof. Safaa Al-Karaksy
Prof. Amani Al-Kholy
Prof. Hala Farawela
Prof. Mona Salah
Prof. Sahar Abdel Atty
Scientific Program Committee
Hematology Committee
Prof. Ali Shams ElDin
Prof. Azza Ahmed
Prof. Naela Omran
Prof. Tayssir Eyada
Prof. Hanaa Arnaout
Microbiology Committee
Prof. Walaa Gad
Prof. Souhair Helal
Prof. Amani Al-Kholy
Prof. Mona Wassif
Prof. Nevine El-Rasheedy
. Immunology Committee
Prof. Nawal Affifi
Prof. Nehad El-Sheemy
Prof. Safaa Al-Karaksy
Prof. Taghrid Gaafar
Prof. Mervat Al-Ansary
Chemistry Committee
Prof. Omar Al-Roubi
Prof. Omnia Youssef
Prof. Mona Salem
Prof. Fayza Abdel Hamid
Prof. Nadida Gohar
26

27. ENTRANCE TO THE HALL
PANEL
AUDIENCE
27

28. 2nd ClinChem Conference 2010
"Transfusion Medicine & Quality updates: Revolution not
evolution" that was held on the 24th of October, 2010 at the
Learning Resources center at Kasr Al-Ainy Faculty of Medicine
General info
Prof. Dr. Ahmed El-Saifi
Conference President
Prof. Dr. Mervat Al-Ansary
Conference Vice President
Dr. Nelly Abulata
Conference Coordinator
Organizing Committee
Prof. Dr. Hala Gabr
A. Prof. Nermeen El-Dessouky
Dr. Rania Zayed
Dr. Heba El-Baz
Dr. Heidi Goubran
Scientific Program Committee
Prof. Dr. Nawal Afifi
Prof. Dr. Azza Mostafa
Prof. Dr. Safa Al-Karaksy
Prof. Dr. Mervat Al-Ansary
Prof. Dr. Azza Abou El-Enain
Prof. Dr. Amaal El-Beshlawy
Prof. Dr. Mervat Mattar
Prof. Dr. Fikri Goubran
Prof. Dr. Faten Moftah
Prof. Dr. Magdy El-Ekiaby
28

29. ENTRANCE TO HALL
AUDIENCE
NETWORKING
29

30. 5- Postgraduate Library
The Department upgraded its postgraduate library books with the latest books in Hematology,
Immunology, Microbiology, Genetics, Chemistry in addition to a range of books concerned with eLearning, Presentation skills, Research methodology & Quality Assurance. The new books
include:
Hematology
1. Hemato-pathology atlas (2009)
2. Clinical Laboratory Haematology(2009)
3. Haematology Clinical cases :Q&A (2009)
Transfusion Medicine
1. Transfusion Medicine & haemostasis(2009)
2. Practical Transfusion Medicine (2009)
Immunology
1. Cellular & Molecular Immunology (2010)
2. Cell biology & genetics (2008)
3. Q&A in Immunology & Microbiology(2010)
Microbiology
1. Microbiology (2010)
2. Medical Mycology (2009)
3. Case files in Microbiology (2009)
4. Q&A in Immunology & Microbiology(2010)
New era books
Chemistry
1. Clinical Chemistry (2010)
2. Clinical Chemistry (2010)
3. Clinical Biochemistry Metabolic and
clinical aspects (2008)
4. Endocrine & Diabetes Clinical cases:
Q&A (2009)
5. Q&A in Biochemistry (2010)
6. Drug assay (2010)
Molecular
1. Genetics: Analysis& Principles(2008)
2. Advanced Genetic analysis (2009)
Miscellaneous
1. Manual of Laboratory diagnostics
(2008)
2. Phlebotomy (2009)
1. Management (2008)
2. Medical Ethics (2010)
3. Medical Quality management (2008)
Educational books (new)
1. Curriculum Leadership (2010)
2. Challenging e-learning in the University (2009)
3. Educational Research in Higher Education (2010)
4. Learning and Teaching in Higher Education (2009)
5. Presentation skills the Complete Handbook (2008)
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31. 6- Website redesign & updating:
The website for the Clinical & Chemical Pathology Department has been redesigned,
expanded, updated, and published on the internet at: http://www.clinchemcairo.org
Home About us Laboratory Services Projects Teaching &Training
Faculty Events Contact us
Please contact us for additional information about our Department.
Prof. Dr. Ahmed El-Saifi,
Saifi,
MD Chair, Department of Clinical and Chemical Pathology
Contact the Chair's Office
2010 Annual Progress Report
2009 Annual Progress Report
31