1. iExplore: A provenance-based application for
exploring biomedical knowledge
Vinh Nguyen, Olivier Bodenreider, Thomas Rindflesch, Amit Sheth

2. Why iExplore?
• Biomedical Knowledge Repository (BKR)
– Developed at NLM
– Integrating various knowledge sources
– Represented in RDF
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3. How to explore BKR?
• Large knowledge base
– 71 milliion triples in the BKR Instances
– 4 million triples in the BKR Schema
• Modeled from
– 2 million Metathesaurus concepts
– Semantic predications extracted from PubMed
abstracts (2000-2009) by SemRep
• Broad domain coverage
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4. Approach
• Graph visualization
• Interactive exploration
• Explore either PubMed or UMLS
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5. Demo
iExplore is available at
http://knoesis.wright.edu/iExplore/iExplore.html
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6. Technologies
• Semantic Web
– RDF, SPARQL standards
– Virtuoso triple store
• iExplore development
– Client side: Adobe Flex
– Server side: Java
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7. Q&A
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