This document summarizes climate-smart agriculture (CSA) options for mixed crop-livestock systems in sub-Saharan Africa. It discusses the importance of these systems for food security now and in the future given population growth. Several CSA practices are presented and evaluated based on their potential impacts on production, resilience, mitigation, feasibility, and adoption constraints. The analysis finds that CSA options often involve trade-offs. Additionally, broad-brush targeting of interventions is not appropriate given context-specific impacts. Improving the evidence base and addressing adoption constraints will help scale up promising CSA practices.