This document discusses the importance of alignment for the Comprehensive Africa Agriculture Development Programme (CAADP) to sustain its momentum. It notes some successes of CAADP including aligning technical and political processes, but also failures like overfocus on financing and supply issues. Stakeholders want stronger coordination, a coherent African vision, and less talk with more action. The document argues CAADP must help countries respond to challenges like youth unemployment and urbanization. It stresses the need to align science agendas and CGIAR with CAADP to drive an agriculture-led transformation in Africa centered around strengthening institutions, policies, and people.