A case of unsteadiness and limb weakness

A Case of Unsteadiness and Limb Weakness Dr Richard McCrory CT2 Medicine 9 th March 2011

Case Presentation: Mrs E.W. (1) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Mrs E.W. (2) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Initial assessment 27/8/10 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Initial Investigations ,[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

But there’s more… ,[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

But there’s (still) more… ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Investigations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object]

CT Chest/Abdo/Pelvis 19/10/10 ,[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Final Diagnosis – Paraneoplastic Cerebellar Degeneration secondary to Primary B-Cell Lymphoma of the Breast

The Cerebellum – A Brief Overview of Functional Anatomy ,[object Object],[object Object],[object Object]

Paraneoplastic Neurological Syndromes ,[object Object],[object Object]

Paraneoplastic cerebellar degeneration (PCD) ,[object Object],[object Object],[object Object],[object Object],[object Object]

Clinical Features of PCD ,[object Object],[object Object]

A Large Diagnostic Differential ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Findings not Consistent with paraneoplastic cerebellar degeneration ,[object Object],[object Object],[object Object],[object Object],[object Object]

Investigations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Prognosis ,[object Object],[object Object],[object Object]

Take Home Messages ,[object Object],[object Object]

A case of unsteadiness and limb weakness

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A case of unsteadiness and limb weakness