1. Diabetes Mellitus DR SHABEEL’S PRESENTATIONS

4. Pathophysiology & clinical features

5. Lack of insulin Decreased peripheral Uptake of glucose Hyperglycemia Osmotic diuresis Glycosuria Na, H2O depletion

6. Lack of insulin Decreased peripheral Uptake of glucose Hyperglycemia Osmotic diuresis Glycosuria Na, H2O depletion Polyuria Polydipsia Fatigue Vulvitis Balanitis Tachycardia Hypotension

7. Lack of insulin Decreased peripheral Uptake of glucose Hyperglycemia Osmotic diuresis Glycosuria Na, H2O depletion Increased breakdown of glycogen & lipid Ketone bodies Acidosis

8. Lack of insulin Decreased peripheral Uptake of glucose Hyperglycemia Osmotic diuresis Glycosuria Na, H2O depletion Increased breakdown of glycogen & lipid Ketone bodies Acidosis Wasting & loss of weight Hyperventilation Peripheral vasodilatation Hypotension Hypothermia

20. Diabetic ketoacidosis

21. Pathophysiology Marked hyperglycaemia Osmotic diuresis Dehydration & electrolyte imbalance

28. Hypoglycemia