Medical college lectures: Medical helminths 3nd year.

1. Helmentic infections: Dr.Mohamad Shaikhani.

6. Roundworms(Nematodes). Round worms(asaris lumbricoides)

12. Treatment for common intestinal nematodes. - - +++ - + Pyrvinium - - + + +++ Levamisole +++ + ++ ++ ++ Thiabendazole ++ + + ++ ++ Albendazole + ++ +++ ++ ++ Mebendazole - +++ - - - Oxantel - - +++ ++ +++ Pyrantel - - +++ + +++ Piperazine Strongyloides Trichuris E.V Hook Asaris

18. Humans Accidental Intermediate Host

22. Cestodes(Tape worms). Echinococcus granulosus & multilocularis(hydatid cysts):

23. Cestodes(Tape worms). Echinococcus granulosus & multilocularis(hydatid cysts): Scolex Adult worm Taenia saginata Infected beef

30. Trematodes(Fluke). Shistosomiasis (Bilharziasis):

32. Trematodes(Fluke). Shistosomiasis (Bilharziasis): pathogenesis & clinical features. Colitis,hepatitis, Portal HT Same. Cystitis, hematuria Immune complex glomerulonephritis. Months. Early egg deposition. Same. Pneumonitis,myositis,hepatitis,fever,eosinophilia,seroconversion. Weeks Larval migration& maturation. Same Papular dermatitis. Days Cercarial penitration Other types. S.Hematobium Time Stage

33. Trematodes(Fluke). Shistosomiasis (Bilharziasis): pathogenesis & clinical features. Colonic polyposis & strictures,periportal firosis, portal hypertension. Same. UB, ureters fibrosis calcification,Ca Infection,stones,hydronephrosis. Pulmonary granulomas & pulmonary hypertension. Years. Late egg deposition. Other types. S.Hematobium Time Stage

35. Trematodes(Fluke). Shistosomiasis (Bilharziasis): Treatment. 7.5mg/kg every 2 weeks * 3 Not useful 40mg/kg once Hematobium Not useful Not useful 40mg/kg*2 in one day Japonicum Not useful 15mg/kg*2*2 days 40mg/kg once Mansoni Metrifonate Oxamniquine Praziquantel Type

37. A: Acute liver granuloma around S mansoni egg in liver. B: Chronic liver granuloma around the remains of a schistosome egg in liver, with dominant fibrous tissue.

38. C: Macrohaematuria due to ulceration of the bladder wall in urinary schistosomiasis. D: Ultrasonography of irregular bladder wall and polyp; E: IVP showing bilateral hydroureter and hydronephrosis.

39. F: Severe bloody diarrhoea due to S mansoni . G: 6-year-old boy with gross hepatosplenomegaly. H: 19-year-old man with symptoms of chronic fibrotic liver schistosomiasis—splenomegaly, external varices, ascites, growth retardation. I: ultrasonography of advanced periportal fibrosis &portal venodilatation;