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2020-06-20
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The Relation between ABM (Agent-Based
Model) and SIR (Susceptible-Infected-
Recovered) Model for Spread of Disease
A. Susandi1,2,*, I. Taufik2, P. Aditiawati2, S. Viridi2
1Badan Intelijen Negara Republik Indonesia
2Institut Teknologi Bandung, Jalan Ganesha 10, Bandung 40132, Indonesia
*armi@meteo.itb.ac.id
2020-06-20
Jakarta, Indonesia
SNF2020 | ABS-261 2
Outline
• Agent-based Model (ABM) and its applications
• Mathematical modelling of infectious disease
• SIR model
• AMB-SIR
• Case 1, 2, 3
• The 2nd wave
• Conclusion (and future plan)
Agent-Based Model (ABM)
• Simulation of many individuals
• Each individual can interact to other individual
• Individual can also interact to enviroment
• Rule of interaction can be so abstract
• Each agent is updated in random order
• Individual can breed, mutate, die, etc..
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Applications of ABM
Large scale
• Optimization in spatial planning [1]
• Predicting future of a city [2]
Mesoscale
• Human interactions in evacuation [3]
• Multilane traffic flow [4]
• Farming system [5]
• Customer behaviour in car purchasing [6]
2020-06-20
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SNF2020 | ABS-261 4
Applications of ABM (cont.)
Microscale
• Mechanics of cells and tissues [7]
• Interaction among red blood cells, macro-
phages, and neutrophils in immune system
during infection [8]
Molecular / atomic scale
• Simulation of state of matter [9]
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SNF2020 | ABS-261 5
Mathematical modelling of infectious disease
For COVID-19
• SIR [10]
• SIRD [11]
• SEIR [12]
• SEIRD [13]
• SEIQRD [14]
• SIDARTHE [15]
Terms
• Susceptible
• Infected
• Recovered
• Death
• Exposed
• Quarantine
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SNF2020 | ABS-261 6
susceptible (S), infected (I), diagnosed (D), ailing (A),
recognized (R), threatened (T), healed (H), extinct (E)
Compartments
Susceptible-Infected-Recovered
• Simple, discrete form, normalized
• Two final states: non-epidemic & epidemic
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iiii isss 1 iiiii iisii  1 iii irr 1
1 iii ris
0.0
0.2
0.4
0.6
0.8
1.0
0 15 30 45 60 75 90
t
s
i
r
0.0
0.2
0.4
0.6
0.8
1.0
0 15 30 45 60 75 90
t
s
i
r
SIR-ABM
• World in square grid □
• Represented in matrix form
• Can move only one □ in direction ← ↑ ↓ →
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Case 1: ABM can, SIR can’t
• Infected agent surrounded by recovered ones
ABM predicts no infection spread
• SIR will still predict infection spread, since it
does not take into account spatial factor
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Case 2: ABM clear, SIR not clear
• One in-
fected
agent will
spread
infection
differently
in ABM
• But still the same in SIR, except we change
value of β
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SNF2020 | ABS-261 10
same time t >>
Case 3: Four connected cities
• Infection begins at North-West city, propaga-
ted to South-West city, then to South-East city,
and finally arrives in North-East city
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time t >>
NW NE
SW SE
• The pandemic is
propagated
from city to city
Case 3: ..
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SNF2020 | ABS-261 12
0.0
0.2
0.4
0.6
0.8
1.0
0 15 30 45 60 75 90 105 120 135 150
t
s
i
r
0.0
0.2
0.4
0.6
0.8
1.0
0 15 30 45 60 75 90 105 120 135 150
t
s
i
r
0.0
0.2
0.4
0.6
0.8
1.0
0 15 30 45 60 75 90 105 120 135 150
t
s
i
r
0.0
0.2
0.4
0.6
0.8
1.0
0 15 30 45 60 75 90 105 120 135 150
t
s
i
r
NW
SW
SE
NE
Sum all data from the four cities
• We get the 2nd wave phenomenon, which is
bigger!
2020-06-20
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SNF2020 | ABS-261 13
0.0
0.2
0.4
0.6
0.8
1.0
0 15 30 45 60 75 90 105 120 135 150
t
s
i
r
Conclusions
• ABM gives more details information than SIR
• Phenomenon of second wave can observed
when data of four cities are summed up
Future plan
• Study the network of interaction between
agent: first
infection is
agent 000
2020-06-20
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SNF2020 | ABS-261 14
2020-06-20
Jakarta, Indonesia
SNF2020 | ABS-261 15
References
1. A. Ligtenberg, R. J. A. van Lammeren, A. K. Bregt and A. J. M. Beulens,
Comput. Environ. Urban Syst. 34, 424-434 (2010).
2. F. Hosseinali, A. A. Alesheikh and F. Nourian, Cities 31, 105-113 (2013).
3. E. Bonabeau, PNAS 99, 7280-7287 (2002).
4. R. Sugihakim and H. Alatas, Phys. Lett. A 380, 147-155 (2016).
5. S. Viridi, P. Premadi, P. Aditiawati, E. S. Maqdir, T. Suheri, J. Halid, K. N.
Sari, U. S. Pasaribu, N. M. Sudaryani, N. Latifah and S. Rahimah, IOP
Conf. Ser.: Earth Environ. Sci. 230, 012118 (2019).
6. M. G. Mueller and P. de Haan, Energy Policy 37, 1072-1082 (2009).
7. P. Van Liedekerke, "Quantitative modeling of cell and tissue mechanics
with agent-based models", Biological Physics [physics.bio-ph], Inria
Paris, Sobonne Université, Mar 2019, HAL Id: tel-02064216, url
https://hal.inria.fr/tel-02064216.
References (cont.)
8. Z. Z. Shi, C.-H. Wu and D. Ben-Arieh, Open J. Model. Simul. 2, 12-22
(2014).
9. S. Viridi and F. Haryanto, IOP Conf. Ser. Mat. Sci. Eng. 599, 012008
(2019).
10. M. S. Boudrioua and A. Boudrioua, medRxiv 20079467v6 06 Jun 2020.
11. J. Fernández-Villaverde, C. I. Jones, NBER Working Paper 27128, May
2020.
12. E. Soewono, Commun. Biomath. Sci. 3, 9-18, (2020).
13. I. Korolev, SSRN 3569367, 20 Apr 2020.
14. A. G. M. Selvam and D. Vignesh, Alochana Chakra J. 9, 217-221 (2020).
15. G. Giordano, F. Blanchini, R. Bruno, P. Colaneri, A. Di Filippo, A. Di
Matteo and M. Colaneri, Nat. Med., (2020).
2020-06-20
Jakarta, Indonesia
SNF2020 | ABS-261 16
2020-06-20
Jakarta, Indonesia
SNF2020 | ABS-261 17
Thank you

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The Relation between ABM (Agent-Based Model) and SIR (Susceptible-Infected-Recovered) Model for Spread of Disease

  • 1. 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 1 The Relation between ABM (Agent-Based Model) and SIR (Susceptible-Infected- Recovered) Model for Spread of Disease A. Susandi1,2,*, I. Taufik2, P. Aditiawati2, S. Viridi2 1Badan Intelijen Negara Republik Indonesia 2Institut Teknologi Bandung, Jalan Ganesha 10, Bandung 40132, Indonesia *armi@meteo.itb.ac.id
  • 2. 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 2 Outline • Agent-based Model (ABM) and its applications • Mathematical modelling of infectious disease • SIR model • AMB-SIR • Case 1, 2, 3 • The 2nd wave • Conclusion (and future plan)
  • 3. Agent-Based Model (ABM) • Simulation of many individuals • Each individual can interact to other individual • Individual can also interact to enviroment • Rule of interaction can be so abstract • Each agent is updated in random order • Individual can breed, mutate, die, etc.. 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 3
  • 4. Applications of ABM Large scale • Optimization in spatial planning [1] • Predicting future of a city [2] Mesoscale • Human interactions in evacuation [3] • Multilane traffic flow [4] • Farming system [5] • Customer behaviour in car purchasing [6] 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 4
  • 5. Applications of ABM (cont.) Microscale • Mechanics of cells and tissues [7] • Interaction among red blood cells, macro- phages, and neutrophils in immune system during infection [8] Molecular / atomic scale • Simulation of state of matter [9] 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 5
  • 6. Mathematical modelling of infectious disease For COVID-19 • SIR [10] • SIRD [11] • SEIR [12] • SEIRD [13] • SEIQRD [14] • SIDARTHE [15] Terms • Susceptible • Infected • Recovered • Death • Exposed • Quarantine 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 6 susceptible (S), infected (I), diagnosed (D), ailing (A), recognized (R), threatened (T), healed (H), extinct (E) Compartments
  • 7. Susceptible-Infected-Recovered • Simple, discrete form, normalized • Two final states: non-epidemic & epidemic 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 7 iiii isss 1 iiiii iisii  1 iii irr 1 1 iii ris 0.0 0.2 0.4 0.6 0.8 1.0 0 15 30 45 60 75 90 t s i r 0.0 0.2 0.4 0.6 0.8 1.0 0 15 30 45 60 75 90 t s i r
  • 8. SIR-ABM • World in square grid □ • Represented in matrix form • Can move only one □ in direction ← ↑ ↓ → 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 8
  • 9. Case 1: ABM can, SIR can’t • Infected agent surrounded by recovered ones ABM predicts no infection spread • SIR will still predict infection spread, since it does not take into account spatial factor 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 9
  • 10. Case 2: ABM clear, SIR not clear • One in- fected agent will spread infection differently in ABM • But still the same in SIR, except we change value of β 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 10 same time t >>
  • 11. Case 3: Four connected cities • Infection begins at North-West city, propaga- ted to South-West city, then to South-East city, and finally arrives in North-East city 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 11 time t >> NW NE SW SE
  • 12. • The pandemic is propagated from city to city Case 3: .. 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 12 0.0 0.2 0.4 0.6 0.8 1.0 0 15 30 45 60 75 90 105 120 135 150 t s i r 0.0 0.2 0.4 0.6 0.8 1.0 0 15 30 45 60 75 90 105 120 135 150 t s i r 0.0 0.2 0.4 0.6 0.8 1.0 0 15 30 45 60 75 90 105 120 135 150 t s i r 0.0 0.2 0.4 0.6 0.8 1.0 0 15 30 45 60 75 90 105 120 135 150 t s i r NW SW SE NE
  • 13. Sum all data from the four cities • We get the 2nd wave phenomenon, which is bigger! 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 13 0.0 0.2 0.4 0.6 0.8 1.0 0 15 30 45 60 75 90 105 120 135 150 t s i r
  • 14. Conclusions • ABM gives more details information than SIR • Phenomenon of second wave can observed when data of four cities are summed up Future plan • Study the network of interaction between agent: first infection is agent 000 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 14
  • 15. 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 15 References 1. A. Ligtenberg, R. J. A. van Lammeren, A. K. Bregt and A. J. M. Beulens, Comput. Environ. Urban Syst. 34, 424-434 (2010). 2. F. Hosseinali, A. A. Alesheikh and F. Nourian, Cities 31, 105-113 (2013). 3. E. Bonabeau, PNAS 99, 7280-7287 (2002). 4. R. Sugihakim and H. Alatas, Phys. Lett. A 380, 147-155 (2016). 5. S. Viridi, P. Premadi, P. Aditiawati, E. S. Maqdir, T. Suheri, J. Halid, K. N. Sari, U. S. Pasaribu, N. M. Sudaryani, N. Latifah and S. Rahimah, IOP Conf. Ser.: Earth Environ. Sci. 230, 012118 (2019). 6. M. G. Mueller and P. de Haan, Energy Policy 37, 1072-1082 (2009). 7. P. Van Liedekerke, "Quantitative modeling of cell and tissue mechanics with agent-based models", Biological Physics [physics.bio-ph], Inria Paris, Sobonne Université, Mar 2019, HAL Id: tel-02064216, url https://hal.inria.fr/tel-02064216.
  • 16. References (cont.) 8. Z. Z. Shi, C.-H. Wu and D. Ben-Arieh, Open J. Model. Simul. 2, 12-22 (2014). 9. S. Viridi and F. Haryanto, IOP Conf. Ser. Mat. Sci. Eng. 599, 012008 (2019). 10. M. S. Boudrioua and A. Boudrioua, medRxiv 20079467v6 06 Jun 2020. 11. J. Fernández-Villaverde, C. I. Jones, NBER Working Paper 27128, May 2020. 12. E. Soewono, Commun. Biomath. Sci. 3, 9-18, (2020). 13. I. Korolev, SSRN 3569367, 20 Apr 2020. 14. A. G. M. Selvam and D. Vignesh, Alochana Chakra J. 9, 217-221 (2020). 15. G. Giordano, F. Blanchini, R. Bruno, P. Colaneri, A. Di Filippo, A. Di Matteo and M. Colaneri, Nat. Med., (2020). 2020-06-20 Jakarta, Indonesia SNF2020 | ABS-261 16