1. University of Washington
WERA Update 2009
Steven Roberts

2. • Pathogens
• Shellfish Genomics

3. Pathogens
• Vibrio tubiashii

4. Vibrio tubiashii
226 million bp

5. Vibrio tubiashii
chitinase, serine protease, RSE

6. Genomics
• Basics
• Crassostrea gigas
• Disease Tolerance
• Crassostrea virginica
• Haliotis cracherodii
• Mercenaria mercenaria

7. C. gigas plated hemocytes
Roberts et al 2009

8. C. gigas plated hemocytes
Roberts et al 2009

9. C. gigas Vibrio challenge
Roberts et al 2009

10. C. gigas Vibrio challenge
Roberts et al 2008

11. C. gigas Vibrio challenge
Prostaglandin
E2 receptor
EP4 subtype

12. Prostaglandins
Gavery; Poster

13. Value-added

14. Disease Resistance
• C. virginica
• H. cracherodii
• M. mercenaria

15. C. virginica

16. H. cracherodii

17. H. cracherodii

18. M. mercenaria
photo: Dale Leavitt (RWU)

19. Other stuff
• Epigenetics (methylation)
• Gene annotation effort? (wiki)