4. Differentiation between Anti-clostridial drugs
MetrocolO.A.PAmoxy.Ampc.ClindamycinLincomycinStrep.BMDCriteria
Absorbed.Absorbed.
Absorbed but
its absorption is
reduced by
feed without
chelation.
Absorbed but
its absorption is
reduced by
feed without
chelation.
Absorbed and its
absorption is not
affected by
chelation with
feed.
Absorbed but its
absorption is
reduced by
chelation with
feed.
Poorly
absorbed
Poorly
absorbed
Absorption
Highly
effective
on NE +
UE + GD
Moderate
on NE.
Poor on
UE No
effect on
GD.
Moderate on
NE. Poor on
UE. No effect
on GD.
Moderate on
NE. Poor on
UE & not GD.
Effective on NE
+ UE + GD
NE + UE and No
effect on GD.
UE only
NE + UE
and not GD
Efficacy on
Clostridial
infections
---------+++++++++------Recycling
Renal
mainly.
Renal
mainly.
Renal mainly.
Bile mainly &
renal
Bile mainly and
renal rarely
Bile mainly and
renal rarely
FecalFecalExcretion
20 mg/Kg/
3-4 days
400.000
IU/Kg / 3-4
days
40 mg/Kg / 3-4
days
40 mg/Kg / 3-4
days
15 mg/Kg/3-4
days
22 mg/Kg /3-4
days
0.5 g/L/3-4
days
80 mg/L/3-4
days
Dose
Coccidiosis
(++)
---
Systemic
bacteria
Enteric bacteria
Mycoplasmosis
(+++)
Mycoplasmosis
(++)
------
Associated
functions