For better view, press F5. As we go through our lives each of us will have very different needs for our own healthcare. Scientist's are constantly researching to make medical care treatment more personalized. One way they are doing this is by- Stem Cells therapy Stem-cell therapy is the use of stem cells to treat or prevent a disease or condition. It is also known as regenerative medicine, promotes the reparative response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. It is the next chapter of organ transplantation and uses cells instead of donor organs, which are limited in supply. What are Stem cells? Stem cells are called “master cells” Stem cells are cells that are undifferentiated. What are Stem cells? Steam cells have the potential to become all other kinds of cells in our body. What are Stem cells? Types of Stem cells How stem cell therapy works? Disease cured by stem cell therapy. Spinal Cord Injuries Stem cell treatment of Diabetes mellitus type 1 & 2 Stem cell treatment of Stroke Cancer treatment Heart damage Baldness Tooth implanting Deafness and blindness Have stem cells already been used to treat diseases? Ethical Consideration of Stem Cell Therapy As the research method mainly focused on Embryonic Stem Cells, which involves taking tissue from an aborted embryo to get proper material to study. This is typically done just days after conception or between the 5th and 9th week. Since then, researchers have moved on to more ethical study methods, such as Induced Pluripotent Stem Cells (iPS). iPS is artificially derived from a non-pluripotent cell, such as adult somatic cells. Nowadays stem cell treatment has been spreaded throughout the world. It has also been grown commercially in developed countries. It is thought that one day it may be the major key to treat various diseases. Using stem cells to conduct medical research and treat disease is acceptable? Don’t know No Yes Do you approve of the extraction of stem cells from human embryos for medical research? Don’t know No Yes

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2. Presented by :
Md.Waliullah Wali
ID# 15276002
Department of M.N.S.
BRAC University

3. CONTENTS
Stem-cell therapy
Types of Stem cells
How therapy works ?
Disease cured by SC therapy
Ethical Consideration
Stem cells

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Imaging two people are listing to musicWhat are the odds that they are listing to the exact
same Play list ???
Similarity Probably very low !!!
After all, Every one has different
tastes in music.

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Even lower !!!
Now, What are the odds that our body will need
the exact same medical care treatment as
another person’s body ???

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As we go through our lives each of us will
have very different needs for our own
healthcare.

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Scientist's are constantly researching to
make medical care treatment more
personalized.

8. 8
One way they are doing this is by-
Stem Cells therapy

9. Stem-cell therapy
Stem-cell therapy is the use of stem cells to treat or prevent a
disease or condition.
It is also known as regenerative medicine, promotes the
reparative response of diseased, dysfunctional or injured tissue
using stem cells or their derivatives.
It is the next chapter of organ transplantation and uses cells
instead of donor organs, which are limited in supply.
9

10. What are Stem cells?
Stem cells are called “master cells”
Stem cells are cells that are undifferentiated.

11. What are Stem cells?
Steam cells have the potential to become all other kinds of cells in
our body.
protects our body contract send signals
do not have
any specific
functions
the body is made up of about 200 different kinds of specialized cells
all cells in the body come from stem cells

12. What are Stem cells?
Replicate itself
Differentiate into many cell
types
A single cell

13. Types of Stem cells
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Stem cells
Pluripotent Stem Cells
Embryonic Stem Cells
(ESCs)
Induced Pluriptoent Stem
Cells (iPSCs)
Adult or Multipotent Stem Cells
Mesenchymal Stem Cells
(MSCs)
Neural Stem Cells (NSCs)
Hematopoietic Stem Cells
(HSCs)
Cancer Stem Cells (CSCs)

14. How stem cell therapy works?
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 When stem cells are transplanted into the body and arrive into the
injured part,
 brain being targeted for tissue regeneration,
 the stem cells are coming in contact with growth chemical’s (like
EGF’s , NGF’s and HGF’s )in the body.
 These chemicals program the stem cells to differentiate into the
tissue surrounding it.

15. Disease cured by stem cell therapy.
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Spinal cord injuries.
Diabetes mellitus.
Cancer.
Stroke.
Tooth implanting .
Deafness and blindnes.
Baldness.etc.

16. Spinal Cord Injuries
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 The stem cells are first collected from a
patient’s bone marrow, extracted from the
hipbone, then implanted back into the body
later.
 These re-injected stem cells have the
potential to transform into multiple types of
cells and are capable of regenerating
damaged tissue.

17. Stem cell treatment of Diabetes mellitus type 1 & 2
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 Adult stem cell therapy with autologous stem cells
fights type 1 and type 2 diabetes at its roots, reducing
hyperglycemia.
 These re-injected stem cells are capable of
regenerating damaged cells such as pancreatic beta
cells.

18. Stem cell treatment of Stroke
18
 A cerebrovascular accident is also known as a stroke.
 The stem cells are collected from patient’s bone marrow.
 These cells are re-injected into the damaged tissue have
the potential to transform into multiple types of cells and
are capable of regenerating the damaged tissue.

19. Cancer treatment
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 Umbilical cord blood stem cells have been used to treat
cancer patients with conditions such as leukemia and
lymphoma.
 The unfortunate side effect of the chemotherapy that
the Stem Cell Transplant attempts to reverse.

20. Heart damage
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 Several clinical trials targeting heart disease have shown
that adult stem cell therapy is safe and effective.
 Adult stem cell therapy for heart disease was
commercially available on at least five continents.

21. Baldness
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 Hair follicles also contain stem cells, and some researchers predict research on
these follicle stem cells may lead to successes in treating baldness through
"hair multiplication", also known as "hair cloning",
 treatment is expected to work through taking stem cells from existing
follicles, multiplying them in cultures, and implanting the new follicles into
the scalp

22. Tooth implanting
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 stem cells taken from the patient could be coaxed in the
lab into turning into a tooth bud which, when implanted in
the gums, will give rise to a new tooth.
 It will fuse with the jawbone and release chemicals that
encourage nerves and blood vessels to connect with it .

23. Deafness and blindness
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 There has been success in regrowing cochlea sensory
hair cells with the use of stem cells.
 Using embryonic stem cells, scientists are able to
grow a thin sheet of totipotent stem cells in the
laboratory. When these sheets are transplanted over
the damaged retina, the stem cells stimulate renewed
repair, eventually restoring vision

24.  Doctors have performed stem cell transplants, also known as
bone marrow transplants.
 In stem cell transplants, stem cells replace cells damaged by
chemotherapy or as a way for the donor's immune system to
fight some types of cancer and blood-related diseases, such as
leukemia.
 These transplants use adult stem cells.
 Researchers are testing adult stem cells to treat other
conditions, including a number of degenerative diseases such as
heart failure.
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Have stem cells already been used to treat
diseases?
Yes

25. Ethical Consideration of Stem Cell Therapy
25
 As the research method mainly focused on Embryonic Stem Cells, which involves
taking tissue from an aborted embryo to get proper material to study. This is
typically done just days after conception or between the 5th and 9th week.
 Since then, researchers have moved on to more ethical study methods, such as
Induced Pluripotent Stem Cells (iPS). iPS is artificially derived from a non-
pluripotent cell, such as adult somatic cells.
 Nowadays stem cell treatment has been spreaded throughout the world. It has
also been grown commercially in developed countries.
 It is thought that one day it may be the major key to treat various diseases.

26. Using stem cells to conduct medical research and treat
disease is acceptable?
 Don’t know
 No
 Yes
3%
5%
92*%
Biotechnology
Australia –
Community
Attitudes to
Biotechnology
(2007)
* Compares to 80% in 2005 survey
But which type of stem cells?
- pluripotent stem cells (embryonic, SCNT, iPS stem cells)
- tissue stem cells (foetal, cord, adult)

27. Do you approve of the extraction of stem cells from
human embryos for medical research?
 Don’t know
 No
 Yes
Roy Morgan Poll
(2006)
5%
13%
82%

28. Thank You All