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DATA MANAGEMENT 101
October 11, 2013
Hello there!
1 | Data definitions
2 | Dealing with Data
3 | The Next Steps
1 |Data definitions
asdf

Data can be complex
Data can be amazing
Data are about discovery
But…
Data does not speak for itself…
YOU speak for YOUR data
and you need to manage it
But, even more fundamentally…
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1795 C

tomahto

Solanum
lycopersicum
tdTomato
554ex 581em

$64
Data means different things
to different people
Data is not static
1. Brilliant Idea!
2. Design Experiment
3. Do Experiment

The data timeline

4. Collect data
5. Compile and Analyze
6. Publish
7. Fame, Fortune
1. Brilliant Idea!
2. Design Experiment
3. Do Experiment
4. Collect data

The data timeline:
What people think

5. Compile and Analyze
6. Publish

7. Fame, Fortune
Idea!

Analyzing data

The data timeline:
What Happens

experiment
Compile data

design
Other
People’s
data
Try #2
Failure!!
beer
#896
#896

6. Publish
The data cycle:
What Really Happens
2 |dealing with data
Why should I care?
Hello there!
So you won’t go crazy

Efficiency
Accelerates scientific discovery
Reproducibility of science

Credit where credit is due

Personal organization
Do you get frustrated with…
Hello there!
a. Storing data
b. Backing up data
c. Analyzing/manipulating data
d. Finding data produced by other researchers
e. Ensuring data are secure
f. Making data accessible to other researchers
g. Controlling access to data
h. Tracking updates to data (ie versioning)
i. Creating metadata 
j. Protecting intellectual property rights 
k. Ensuring appropriate professional credit/citation is given
How do I not go crazy?
naming|metadata |standards | tools
naming
Naming: File Names
File naming
File naming
Naming conventions

s/n, variable

Retain order

Project_instrument_location_YYYYMMDDhhmmss_extra.ext
Index/grant

conditions

Leading zero!
Experiment: stem cells on fibrin to damaged heart
Lamar Soutter Library UMMS
‐2 days:  Incubate stem cells with markers

‐1 day:  Stem cells in solution with biological suture

0 day: #1 Surgery: infarct/delivery of stem cells to damaged heart tissue 
Variable days:  #2 Surgery:  examination, high speed imaging/LVPs, 
isolate heart and place it in freezer 
Post days +:  Section heart, tissues on slides, staining, images of tissues, 
tracking particles on heart  
Collective data from experiment
‐2 days:  Incubate stem cells with markers

‐1 day:  Stem cells in solution with biological suture

0 day: #1 Surgery: infarct/delivery of stem cells to damaged heart tissue 

TIME | TYPE | USE

Variable days:  #2 Surgery:  examination, high speed imaging/LVPs, 
isolate heart and place it in freezer 
Post days +:  Section heart, tissues on slides, staining, images of tissues, 
tracking particles on heart  
Collective data from experiment
Data

File Format

Images

Machine dependent

Ventricular pressure 
measurements

Proprietary 

Home made software

MATLAB or C

Histology sections

Slides and images

Contextual

Project, Experiment, Animal

Many different file types
Data

File Format

Name

Images

Machine 
dependent

Scope_Date_Var

Ventricular 
pressure 
measurements

Proprietary 

M_Date_Var.raw

Home made 
software

MATLAB or C

Script_Date_Var

Histology 
sections

Slides and images

Anat_Date_Stain

Separate Nomenclature
Data

File Format

Name

Images (1)

Machine 
dependent

E_1_Date_var

Ventricular 
pressure 
measurements 
(2)

Proprietary 

E_2_Date_Var

Home made 
software (3)

MATLAB or C

E_3_Script_Var

Histology 
sections (4)

Slides and images

E_4_Date_Stain

Unified Nomenclature
Type

Recommended

Avoid for data sharing

Tabular data

CSV, TSV, SPSS portable

Excel

Text

Plain text, HTML, RTF
PDF/A only if layout matters

Word

Media

Container: MP4, Ogg
Codec: Theora, Dirac, FLAC

Quicktime
H264

Images

TIFF, JPEG2000, PNG

GIF, JPG

Structured data

XML, RDF

RDBMS

Recommended File Formats
RESOURCES

• Bulk Rename Utility (Windows)
• Renamer (Mac)
• PSRenamer
• Mendeley
Bulk File Renaming Tools
Naming conventions

Grant_Project_experiment_instrument_location_weather_catsname_i
cecreamflavor_collaborator_owner_zodiacsign_mousemodel_address
_painscalerating_favoritecolor_ssn_shoesize_sex_eyecolor_tattoos_
scars_votingrecord_YYYYMMDDhhmmss_extra.ext
Naming: Directory Structure
Presentations

Data presentation
CTSAconnect presentation
Monarch presentation

SPARC

CTSAconnect

Monarch
RESOURCES

www.coggle.it

http://ftp.ihmc.us/

www.mindjet.com

Mindmapping Software
Oldie but goodie…
Naming: Version Control
DataManagement@UPR_seminars_101113_JW
DataManagement@UPR_data_101113_JW
DataManagement_dataship_100313_NV_JW_MH_RC
Data101_dataship_091113_FINAL_JW
Data101_dataship_091013_v04_JW
DataManagement_dataship_091013_v03_JW
DataManagement_dataship_090913_v02_JW
DataManagement_dataship_090913_v01_JW
DataManagement_SPARC_082013_FINAL_NV
DataManagement_SPARC_052013_v8
RESOURCES

Dropbox | Google docs
GIT | SMART SVN

Version Control
Naming: Backups
Which of the following do you do?
a. Save copies of data on a disk, USB drive, or computer
hard drive
b. Save copies of data on a local server
c. Save copies of data on a central campus server
d. Save copies of data on a web based or cloud server
e. Store data in a repository or archives
f. Automatically backup files
g. Manually generate backup
h. Restrict access to files
3 | copies (you, lab, other)
2 | 2 different forms
1 | remote location
ETHICS
Computing in the cloud
How do I not go crazy?
naming|metadata |standards | tools
Metadata/ Controled Vocab/Ontologies
You speak for your data
How do you speak for your data
when you are not around?
Metadata
Controlled
Vocabularies
How do you speak for your data
ontologies
when you are not around?
What it is
Controlled vocabularies
metadata
What it takes to do it
Relevant variables

Controlled vocab

definitions
grouping

ontologies

classification
connection
What is metadata, really?
Hello there!
a. a philosophy
b. describes data
c. dating site
d. data
Title
Author
Call number
Publisher
ISBN
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
metadata

Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
metadata

Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
Metadata
metadata

Your metadata should
make your data
understandable to
others without your
involvement

- Anne Gilliland
File name

File type

Title
Date created

Who created the 
data
RESOURCES

http://www.dlib.indiana.edu/~jenlrile/metadatamap/

Metadata standards
RESOURCES

http://rs.tdwg.org/dwc/

Metadata standards
What is controlled vocab, really?
Hello there!
Craigslist search: Chaise

Craigslist search: Fainting couch
acetominophen
PubMed indexes articles with 
MeSH Terms
What is an ontology, really?
Hello there!
Human Disease:

PFEIFFER
SYNDROME

Coronal
craniosynostosis
HP:0004440

Hypoplasia of
the maxilla
HP:0000327

Cross-species
Phenotype

premature
suture
closure

Most similar
mouse model:
CD1.Cg-Fgfr2tm4Lni/H

premature
suture closure
MP:0000081

maxilla
hypoplasia
short maxilla
MP:0000097

malocclusion
Dental crowding
HP:0000678

Brachyturricephaly
HP:0000244

Hypertelorism
HP:0000316

malocclusion
MP:0000120

shortened
head

ocular
hypertelorism

shortened
head
MP:0000435

ocular
hypertelorism
MP:0001300
How?
naming|metadata |standards | tools
standards
Meet the Urban Lab

Meet the Urban Lab
The Urban Lab Antibodies

A+ organization!
Percent identifiable

90%
80%
70%
60%
50%
40%
30%
20%
10%
0%
Commerical Ab Catalog number Source organism Target uniquely
identifiable
reported
reported
identifiable

Of 14 antibodies published in 45 articles,
only 38% were identifiable
RESOURCES

AntibodyRegistry.org
Are you aware of data standards in
your field?
@OHSU, 72% said no or didn’t know!
Data standards are the rules by which data are 
described and recorded. In order to share, exchange, 
and understand data, we must standardize the format 
as well as the meaning.
www.usgs.gov/datamanagement/plan/datastandards.php
Many microarray transcriptomics standards
JAMIA:sea‐of‐standards
Reporting
guidelines

Terminology
structure
(Interoperability)

Exchange
Formats
How do these standards work?
Metadata
Controlled
Vocabularies
How do you speak for your data
ontologies
when you are not around?
RESOURCES

Minimum Information for Biological and Biomedical Investigations 
RESOURCES

www.cdisc.org
RESOURCES

www.force11.org/node/4463

biosharing.org/bsg-000532

Minimum Information for 
Biological and Biomedical Investigations 
http://www.biosharing.org/standards/mibbi

Reporting Standards
How?
naming|metadata |standards | tools
tools
RESOURCES

runmycode.org

www.wf4ever‐project.org

galaxyproject.org/

Workflow analysis platforms
RESOURCES

http://opus.bath.ac.uk/32296

www.labarchives.com

www.labguru.com
RESOURCES

https://dmp.cdlib.org/
Uniquely identifying data
www.flickr.com/photos/pmeimon
Digital Object Identifier (DOI)
Example: 10.1371/journal.pbio.1001339

Unique resource identifier (URI)
A URI will resolve to a single location on the web
URIs for people

Repositories use Unique IDs
RESOURCES

Repository Map
RESOURCES

Data Sharing Repositories
3 |next steps
Thinking Beyond the PDF
Raw Science

Small publications

Self-publishing

Datasets

Nanopublications

Blogging

Code

Argument or
passage

Social Media

Experimental
design

Single figure
publications

Comments &
Reviews
Annotations
Research Products
RESOURCES

figshare.com

datadryad.org

thedata.org

www.dataone.org

data.rutgers.edu/

v
n2t.net/ezid

nature.com/scientificdata/

F1000.com/

Data publishing and sharing
You are unique, too
John L Campbell, Research Ecologist, Oregon State 
University, Corvallis OR

John L Campbell, Research Ecologist, Center for 
Research on Ecosystem Change, Durham, NC
RESOURCES

Impact.Story
impactstory.org

www.plumanalytics.com

http://myidp.sciencecareers.org/

orcid.org

Yes, you are an individual!
1 | Data definitions
2 | Dealing with Data
3 | The Next Step
wirzj@ohsu.edu
http://libguides.ohsu.edu/data
Melissa Haendel
Nicole Vasilevsky
Robin Champieux
Thank you!
Questions?
what happens
between publications?
“We are Drowning in
Information but
Starved for
Knowledge”
John Naisbitt
“We are Drowning in
data but
Starved for
Knowledge”
Hello there!

Jackie’s bad paraphrase of John Naisbitt
Dr. Sawyer

Dr. Finn

Connected?

University

Collegeville College

University of Badass

No

Journals

Journal of Information

Journal of Data

No

Grant Title

Protein G is Important

Protein H is Important

No
Dr. Sawyer

Dr. Finn

Connected?

Machines Used

Alpha, Gamma, Theta, 
Sigma

Gamma, Beta, Kappa, Theta

Yes!

Reagents Used

Cyan,  Orange, Green, 
Mauve, Beige

Mauve, Chartreuse, Cyan, 
Green, Taupe

Yes!

Genes Referenced

bz3d14.2, bz3c13.1, 
bz3d,98.1

bz3c13.1

Yes!

Proteins Referenced

Eng1a, Ntl, Ncdq

Ndrw, Eng1a, Brs

Yes!

People Affiliated with 
Resources

Harry, Neville, Ron

Harry, Ron, Hermione

Yes!
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