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Nuclei of cranial nerves
Anna L. Kiss
Department Anatomy, Histology and
Embryology
Semmelweis University
Budapest
2018
Cranial nerves:
 they belong to the peripheral nervous system
 12 pairs:
olfactory nerve (I)
optic nerve (II)
oculomotory nerve (III)
trochlear nerve (IV)
trigeminal nerve (V)
abducens nerve (VI)
facial nerve (VII)
vestibulocochlear (stato-acustic) nerve (VIII)
glossopharyngeal nerve (IX)
vagus nerve (X)
accessory nerve (XI)
hypoglossal nerve (XII)
Cranial nerves
Olfactory nerve (I)
Optic chiasma (II)
Optic tract (II)
Oculomotory nerve (III)
Trochlear nerve (IV)
Trigeminal nerve (V)
Facial nerve (VII)
Vestibulocochlear nerve (VIII)
Glossopharyngeal+vagus nerves
(IX,X)
Accessory nerve (XI)
Hypoglossal nerve (XII)
Abducens nerve (VI)
Spinal nerves: mixed (sensory, motor
sometimes vegetative fibers)
radix posterior
radix anterior
ganglion spinale
nervus spinalis
Cranial nerves
Functionally:
Somatic: voluntary Visceral (vegetative):
autonom, unvoluntary
Sensory:
about the outside
world; structures
developed from
embryonic ectoderm
and somatic mesoderm
Motory:
controlling voluntary
muscles, derived from
somites and embryonic
gill arches
Sensory:
viscera
developed
from ectoderm
and splanchnic
mesoderm
Motory:
controlling
function of the
viscera
(symphatetic and
parasymphatetic)
general somatic afferent
GSA
somatic efferent
SE
general visceral afferent
GVS
visceral efferent
VE
• Olfactory nerve (I): is developing as an early part of the primitive
telencephalon
• Optic nerve (II): is developing as an outpouching from the
diencephalon
• Carnial nerves III to XII:
originate from the brain stem
are embryologically homologous with spinal nerves
nuclei of them derived originally from cell columns
homologous with the columns of the spinal cord
Special sensory cranial nerves
• Olfactory nerve (I)
• Optic nerve (II)
• Vestibulocochlear nerve (VIII)
Cranial nerves
• Motor nerves:
• IV, VI, XII – somatomotor
• III – somatomotor, visceromotor
• Sensory:
• VIII – special (hearing, balance)
• Mixed:
• V, VII, IX, X - sensory, motor + vegetatíve
(exept: V)
• Special motor:
• XI (motoros – spinal fibers)
• Not really cranial nerves:
• I, and II – outgrowth of the central nervous system
Oculomotory nerve (III)
• Somatomotory innervation of the muscles of the eye and
parasympathetic motor innervation to the pupil
cerebral aqueduct
central gray matter
parasympathetic nucleus
(Edinger-Westfal)
somatomotor nucleus
crus cerebri
(cerebral peduncle)
Oculomotory nerve (III)
crus cerebri
(cerebral peduncle)
mamillary body
interpeduncular
fossa
oculomotory
nerve (III)
Trochlear nerve (IV)
Somatomotory innervation of the eye muscle: sup. oglique
inf. colliculus
motor nucleus of
cranial n. IV.
red nuclues
Trochlear nerve (IV)
thalamus
pineal body
midbrain
trochlear nerve
Trochlear nerve (IV)
pons
trochlear nerve
Abducens nerve (VI)
Somatomotory innervation of the muscle of the eye:
rectus lateralis m.
thalamus
midbrain
rhomboid fossa,
floor of the IV. ventricle
nucleus of the
abducens nerve:
in the pontine part
of the rhomboid
fossa (IV ventr.)
Abducens nerve (VI)
pons
medulla
oblongata
abducens nerve
III, IV, VI cranial nerves
oculomotory n.
trochlear n.
abducens n.
cavernous sinus
sup. orbital fissure
orbit
Cranial nerves innervating the eye’s
muscles: III, IV, VI
sup. oblique m.
lat. rectus m.
trochlear n.
abducens n.
oculomotory n.
ggl. ciliare
Trigeminal nerve (V)
• Mixed nerve: somatomotory and somatosensory fibers
• Somatomotory fibers: muscles of mastication
• Somatosensory fibers: entire face (form the lower margin of the
mandible to the top of the scalp also the
anterior wall of the auditory tube
dura mater
Mesencephalic n. of V.: is a ganglion
• Autonomic „hitchhikers”: from cranial nerves VII and IX
Trigeminal nerve (V)
Motor nucleus:
pons
main sensory nucleus
(n. sensorius principalis)
pons
mesencephalic n.
n. spinalis
(n. tractus spinalis)
Sensory nuclei:
Trigeminal nerve (V)
trigeminal nerves ganglion (Gasser)
and division of
the trigeminal n.
V/1: ophtalmic
V/2: maxillary
V/3 mandibular
Trigeminal nerve (V)
• V/1: ophtalmic n.:
sup. orbital fissure
Cavernous sinus orbit
Branches: frontal n: skin
lacrimal n.: lacrimal gland (sensory fibers)+”hitchhiker” (VII)
nasociliary n.: eye, nasal cavity, dorsal part of the nose
V/1: Ophthalmic nerve
frontal n.
lacrimal n.
nasociliary n.
Trigeminal nerve (V)
• V/2: maxillary:
Foramen rotundum
Branches: infraorbital n.: upper row of the teeth
zygomatic n.: face along the zygomatic arch
palatine nn.: oral cavity, palate
post. nasal rr : nasal cavity (septum, lateral wall)
V/2 Maxillary nerve
Trigeminal nerve (V)
V/3 mandibular: (carries mainly the motor fibers of the trigeminal n.)
foramen ovale infratemporal fossa mandibular canal
foramen mentale
• Motor branches: to muscles of massication
• Auriculotemporal n.: sensory innervation: temporomandibular joint
tympanic membrane (ant. part)
acustic meatus
parotis
visceromotor innervation: parotis (fibers from CN IX)
• Inf. alveolar n.: sensory innervation: upper row of the teeth
lower lip, skin
motor innervation: mylohyoid, ant. belly of the digastricus m.
• Lingual n.: sensory innervation: general: tongue (ant. 2/3)
taste: chorda tympany (fibers from CN VII)
V/3 Mandibular nerve
auriculotemp. n.
lingual n.
inf. alveolar n.
motor branches
Facial nerve (VII)
• Mixed nerve: somatomotory, viscerosensory, visceromotory fibers
• Somatomotory: mimetic muscles
• Viscerosensory: taste sensation of the anterior 2/3 of the tongue
• Visceromotory: lacrimal gland (V/1 „hitchhicker)
small salivary glands of the nasal cavity and soft palate
sublingual and submandibular gland
Facial nerve (VII)
somatomotor nucleus:
facial colliculus
sensory nucleus:
n. solitarius +
n. tractus solitarii
visceromotor nucleus:
n. salivatorius sup.
pons
medulla
Facial nerve (VII)
facial nerve
Facial nerve (VII)
• Temporal bone (post. surface): facial canal
geniculum: greater petrosal n.
stylomastoid foramen
• Branches: greater petrosal n.: lacrimal gland, salivary glands of the nasal
cavity and soft palate (with V/1)
stapedius n.: motor nerve for stapedius m.
chorda tympany: taste sensory of the ant.2/3 of the tongue
(with V/3)
motor branches to digasticus m. + mimetic muscles
Facial nerve (VII)
greater petrosal n.
stapedius n.
chorda tympani
muscular branches
Glossopharyngeal nerve (IX)
Mixed nerve: somatosensory, somatomotory, viscerosensory and
visceromotory fibers
• Somatosensory: general (pain) from tongue (post 1/3) pharynx
• Somatomory: muscles of the pharynx
• Viscerosensory: taste (post. 1/3 of the tongue) swalloing reflex carotis
sinus
• Visceromotory: parotis parasympathetic innervation (with V/3)
Glossopharyngeal nerve (IX)
Sensory nuclei:
Somatosensory:
n. tractus spinalis of V.
Viscerosensory:
solitary n.
Motor nuclei:
Visceromotor:
salivatory n.
Somatomotor:
n. ambiguus
medulla
medulla
Glossopharyngeal nerve (IX)
glossopharyngeal n.
Glossopharyngeal nerve (IX)
tympanic n.
lesser petrosal n.
ramus sinus
caroticus
ramus lingualis
Vagus nerve (X)
• Mixed nerve: somatosensory, somatomotory, viscerosensory,
visceromotory fibers
• Somatosensory: general sensory+pain
• Somatomotory: striated muscles of pharynx, larynx esophagus
• Viscerosensory: mucosa of the larynx, pharynx trachea, esophagus pleura,
pericardium, lung stomach, organs present in the upper part of the
abdominal cavity
• Visceromotory: glands of the upper mentioned organs
Vagus nerve (X)
Sensory nuclei:
Somatosensory:
tractus spinalis
n. V.
Viscerosensory:
solitary nucleus,
ala cinerea lat.
Motor nuclei:
Somatomotor:
n. ambiguus
Visceromotor:
ala cinerea med.
Vagus nerve (X)
Vagus nerve
Vagus nerve (X)
• Jugular foramen vagina carotica (neck) chest cavity
anterior mediastinum: recurrent laryngeal arteries post. mediastinum
esophagus abdominal cavity
Branches: cervical: ext. acustic meatus, pharynx, larynx
chest cavity: pericardium, pleura, trachea, bronchi, bronchioles,
esophagus
abdominal cavity: stomach, liver, colon
Accessory nerve (XI)
• Motor nerve: (largest part belogs
to cranial nerve X), ext. branch:
sternocleidomastoid + trapezius
m.
N. ambiguus
Accessory nerve (XI)
Accessory n.:
cranial root
spinal root
Jugular foramen
Accessory nerve (XI)
sternocleidomastoid m.
trapezius m.
Hypoglossal nerve (XII)
• Motor nerve: muscles of the
tongue, infrahyoid muscles
hypoglossal n.
Hypoglossal nerve (XII)
hypoglossal nerve
hypoglossal canal
Hypoglossal nerve (XII)
• Neck: between a. carotis comm. and int. jugular vein
• lateral groove of the tongue
ansa cervicalis
Hypoglossal nerve (XII)
hypoglossal nerve
ansa cervicalis

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Cranial-nerves2011gyógytornász.ppt

  • 1. Nuclei of cranial nerves Anna L. Kiss Department Anatomy, Histology and Embryology Semmelweis University Budapest 2018
  • 2. Cranial nerves:  they belong to the peripheral nervous system  12 pairs: olfactory nerve (I) optic nerve (II) oculomotory nerve (III) trochlear nerve (IV) trigeminal nerve (V) abducens nerve (VI) facial nerve (VII) vestibulocochlear (stato-acustic) nerve (VIII) glossopharyngeal nerve (IX) vagus nerve (X) accessory nerve (XI) hypoglossal nerve (XII)
  • 3. Cranial nerves Olfactory nerve (I) Optic chiasma (II) Optic tract (II) Oculomotory nerve (III) Trochlear nerve (IV) Trigeminal nerve (V) Facial nerve (VII) Vestibulocochlear nerve (VIII) Glossopharyngeal+vagus nerves (IX,X) Accessory nerve (XI) Hypoglossal nerve (XII) Abducens nerve (VI)
  • 4. Spinal nerves: mixed (sensory, motor sometimes vegetative fibers) radix posterior radix anterior ganglion spinale nervus spinalis
  • 5. Cranial nerves Functionally: Somatic: voluntary Visceral (vegetative): autonom, unvoluntary Sensory: about the outside world; structures developed from embryonic ectoderm and somatic mesoderm Motory: controlling voluntary muscles, derived from somites and embryonic gill arches Sensory: viscera developed from ectoderm and splanchnic mesoderm Motory: controlling function of the viscera (symphatetic and parasymphatetic) general somatic afferent GSA somatic efferent SE general visceral afferent GVS visceral efferent VE
  • 6. • Olfactory nerve (I): is developing as an early part of the primitive telencephalon • Optic nerve (II): is developing as an outpouching from the diencephalon • Carnial nerves III to XII: originate from the brain stem are embryologically homologous with spinal nerves nuclei of them derived originally from cell columns homologous with the columns of the spinal cord
  • 7. Special sensory cranial nerves • Olfactory nerve (I) • Optic nerve (II) • Vestibulocochlear nerve (VIII)
  • 8. Cranial nerves • Motor nerves: • IV, VI, XII – somatomotor • III – somatomotor, visceromotor • Sensory: • VIII – special (hearing, balance) • Mixed: • V, VII, IX, X - sensory, motor + vegetatíve (exept: V) • Special motor: • XI (motoros – spinal fibers) • Not really cranial nerves: • I, and II – outgrowth of the central nervous system
  • 9. Oculomotory nerve (III) • Somatomotory innervation of the muscles of the eye and parasympathetic motor innervation to the pupil cerebral aqueduct central gray matter parasympathetic nucleus (Edinger-Westfal) somatomotor nucleus crus cerebri (cerebral peduncle)
  • 10. Oculomotory nerve (III) crus cerebri (cerebral peduncle) mamillary body interpeduncular fossa oculomotory nerve (III)
  • 11. Trochlear nerve (IV) Somatomotory innervation of the eye muscle: sup. oglique inf. colliculus motor nucleus of cranial n. IV. red nuclues
  • 12. Trochlear nerve (IV) thalamus pineal body midbrain trochlear nerve
  • 14. Abducens nerve (VI) Somatomotory innervation of the muscle of the eye: rectus lateralis m. thalamus midbrain rhomboid fossa, floor of the IV. ventricle nucleus of the abducens nerve: in the pontine part of the rhomboid fossa (IV ventr.)
  • 16. III, IV, VI cranial nerves oculomotory n. trochlear n. abducens n. cavernous sinus sup. orbital fissure orbit
  • 17. Cranial nerves innervating the eye’s muscles: III, IV, VI sup. oblique m. lat. rectus m. trochlear n. abducens n. oculomotory n. ggl. ciliare
  • 18. Trigeminal nerve (V) • Mixed nerve: somatomotory and somatosensory fibers • Somatomotory fibers: muscles of mastication • Somatosensory fibers: entire face (form the lower margin of the mandible to the top of the scalp also the anterior wall of the auditory tube dura mater Mesencephalic n. of V.: is a ganglion • Autonomic „hitchhikers”: from cranial nerves VII and IX
  • 19. Trigeminal nerve (V) Motor nucleus: pons main sensory nucleus (n. sensorius principalis) pons mesencephalic n. n. spinalis (n. tractus spinalis) Sensory nuclei:
  • 20. Trigeminal nerve (V) trigeminal nerves ganglion (Gasser) and division of the trigeminal n. V/1: ophtalmic V/2: maxillary V/3 mandibular
  • 21. Trigeminal nerve (V) • V/1: ophtalmic n.: sup. orbital fissure Cavernous sinus orbit Branches: frontal n: skin lacrimal n.: lacrimal gland (sensory fibers)+”hitchhiker” (VII) nasociliary n.: eye, nasal cavity, dorsal part of the nose
  • 22. V/1: Ophthalmic nerve frontal n. lacrimal n. nasociliary n.
  • 23. Trigeminal nerve (V) • V/2: maxillary: Foramen rotundum Branches: infraorbital n.: upper row of the teeth zygomatic n.: face along the zygomatic arch palatine nn.: oral cavity, palate post. nasal rr : nasal cavity (septum, lateral wall)
  • 25. Trigeminal nerve (V) V/3 mandibular: (carries mainly the motor fibers of the trigeminal n.) foramen ovale infratemporal fossa mandibular canal foramen mentale • Motor branches: to muscles of massication • Auriculotemporal n.: sensory innervation: temporomandibular joint tympanic membrane (ant. part) acustic meatus parotis visceromotor innervation: parotis (fibers from CN IX) • Inf. alveolar n.: sensory innervation: upper row of the teeth lower lip, skin motor innervation: mylohyoid, ant. belly of the digastricus m. • Lingual n.: sensory innervation: general: tongue (ant. 2/3) taste: chorda tympany (fibers from CN VII)
  • 26. V/3 Mandibular nerve auriculotemp. n. lingual n. inf. alveolar n. motor branches
  • 27. Facial nerve (VII) • Mixed nerve: somatomotory, viscerosensory, visceromotory fibers • Somatomotory: mimetic muscles • Viscerosensory: taste sensation of the anterior 2/3 of the tongue • Visceromotory: lacrimal gland (V/1 „hitchhicker) small salivary glands of the nasal cavity and soft palate sublingual and submandibular gland
  • 28. Facial nerve (VII) somatomotor nucleus: facial colliculus sensory nucleus: n. solitarius + n. tractus solitarii visceromotor nucleus: n. salivatorius sup. pons medulla
  • 30. Facial nerve (VII) • Temporal bone (post. surface): facial canal geniculum: greater petrosal n. stylomastoid foramen • Branches: greater petrosal n.: lacrimal gland, salivary glands of the nasal cavity and soft palate (with V/1) stapedius n.: motor nerve for stapedius m. chorda tympany: taste sensory of the ant.2/3 of the tongue (with V/3) motor branches to digasticus m. + mimetic muscles
  • 31. Facial nerve (VII) greater petrosal n. stapedius n. chorda tympani muscular branches
  • 32. Glossopharyngeal nerve (IX) Mixed nerve: somatosensory, somatomotory, viscerosensory and visceromotory fibers • Somatosensory: general (pain) from tongue (post 1/3) pharynx • Somatomory: muscles of the pharynx • Viscerosensory: taste (post. 1/3 of the tongue) swalloing reflex carotis sinus • Visceromotory: parotis parasympathetic innervation (with V/3)
  • 33. Glossopharyngeal nerve (IX) Sensory nuclei: Somatosensory: n. tractus spinalis of V. Viscerosensory: solitary n. Motor nuclei: Visceromotor: salivatory n. Somatomotor: n. ambiguus medulla medulla
  • 35. Glossopharyngeal nerve (IX) tympanic n. lesser petrosal n. ramus sinus caroticus ramus lingualis
  • 36. Vagus nerve (X) • Mixed nerve: somatosensory, somatomotory, viscerosensory, visceromotory fibers • Somatosensory: general sensory+pain • Somatomotory: striated muscles of pharynx, larynx esophagus • Viscerosensory: mucosa of the larynx, pharynx trachea, esophagus pleura, pericardium, lung stomach, organs present in the upper part of the abdominal cavity • Visceromotory: glands of the upper mentioned organs
  • 37. Vagus nerve (X) Sensory nuclei: Somatosensory: tractus spinalis n. V. Viscerosensory: solitary nucleus, ala cinerea lat. Motor nuclei: Somatomotor: n. ambiguus Visceromotor: ala cinerea med.
  • 39. Vagus nerve (X) • Jugular foramen vagina carotica (neck) chest cavity anterior mediastinum: recurrent laryngeal arteries post. mediastinum esophagus abdominal cavity Branches: cervical: ext. acustic meatus, pharynx, larynx chest cavity: pericardium, pleura, trachea, bronchi, bronchioles, esophagus abdominal cavity: stomach, liver, colon
  • 40. Accessory nerve (XI) • Motor nerve: (largest part belogs to cranial nerve X), ext. branch: sternocleidomastoid + trapezius m. N. ambiguus
  • 41. Accessory nerve (XI) Accessory n.: cranial root spinal root Jugular foramen
  • 43. Hypoglossal nerve (XII) • Motor nerve: muscles of the tongue, infrahyoid muscles hypoglossal n.
  • 44. Hypoglossal nerve (XII) hypoglossal nerve hypoglossal canal
  • 45. Hypoglossal nerve (XII) • Neck: between a. carotis comm. and int. jugular vein • lateral groove of the tongue ansa cervicalis
  • 46. Hypoglossal nerve (XII) hypoglossal nerve ansa cervicalis