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Chapter 3
Excretory System
Chemical Processes in the
Use up
           Body
Oxygen
Glucose
Amino Acids
Water
Nutrients
                          Water,
Produce                Mineral salts,
Carbon dioxide             Urea,
Water                 Carbon Dioxide,
Urea                       Heat
Heat
Toxic Chemicals
Excretory Organs in
               Human



Urinary System       Lungs           Skin

                         Why waste products
                         must be excreted out of
                         the body???
                 Liver
2
Location of the Kidney
Kidney Function
• Detoxify blood
• Increase calcium absorption
  o calcitriol
• Stimulate RBC production
  o erythropoietin
• Regulate blood pressure and electrolyte balance
  o renin
Structure of the Urinary System
                          • Two
                            Kidneys
                          • Two
                            Ureters
                          • Bladder
                          • Urethra
The Blood Supply to the
        Kidney
The Urinary System
Filtration system in the Kidney


                                  Filtration
                                  Mineral salts
                                  Sugar
                                  Amino Acids
                                  Waste-Urea

                                  Reabsorption
                                  All Sugar
                                  All amino acids
                                  Mineral Salts
                                  Water
Function of the Kidney
• Filter blood in order to remove
  cellular waste products from the
  body.
• Maintain chemical composition, pH
  and water level
• At any given time, 20 % of blood is in
  the kidneys. Humans can function
  with one kidney.
• If one ceases to work, the other
  increases in size to handle the
  workload.
Cellular waste
• urea
  o (a nitrogenous waste produced in the liver from the breakdown of
    protein. It is the main component of urine)

• uric acid
  o (usually produced from breakdown of DNA or RNA)

• creatinine
  o (waste product of muscle action).
Composition of
   Chemicals in the Body
 Substance        Blood in     Kidney     Urine
                renal artery   tubules
                                (filter
                               system)
  Glucose           2.0           2.0       0
Mineral salts      10.0         10.0      17.0
Amino acids         0.9          0.9       0
  Protein          88.0           0        0
   Urea             0.5         20.0      20.0
RBC & WBC          47%          0%         0
Kidney failure
•   Urinary Tract Infection
•   Kidney Stone
•   Kidney Infection
•   Diabetic Nephropathy
•   Hypertension
•   Glomerulonephritis
•   HIV nephropathy
Kidney Stone
Treatment of Kidney Failure
        -Dialysis-
• ½ of patients with kidney disease
  eventually require dialysis
• Diffuse harmful waste out of body
• Control BP
• Keep safe level of chemicals in body
• If dialysis cannot work, the patient has
  to undergo kidney transplant
Hemodialysis
• 3-4 times a week
• Takes 2-4 hours
• Machine filters
 blood and
 returns it to
 body
Peritoneal Dialysis
• Abdominal lining filters blood
• 3 types
   o Continuous ambulatory
   o Continuous cyclical
   o Intermittent
Form 3 PMR Science Chapter 3 Excretory System
Form 3 PMR Science Chapter 3 Excretory System

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Form 3 PMR Science Chapter 3 Excretory System

  • 2. Chemical Processes in the Use up Body Oxygen Glucose Amino Acids Water Nutrients Water, Produce Mineral salts, Carbon dioxide Urea, Water Carbon Dioxide, Urea Heat Heat Toxic Chemicals
  • 3. Excretory Organs in Human Urinary System Lungs Skin Why waste products must be excreted out of the body??? Liver
  • 4.
  • 5. 2
  • 6.
  • 7.
  • 9. Kidney Function • Detoxify blood • Increase calcium absorption o calcitriol • Stimulate RBC production o erythropoietin • Regulate blood pressure and electrolyte balance o renin
  • 10. Structure of the Urinary System • Two Kidneys • Two Ureters • Bladder • Urethra
  • 11. The Blood Supply to the Kidney
  • 12.
  • 13.
  • 14.
  • 16. Filtration system in the Kidney Filtration Mineral salts Sugar Amino Acids Waste-Urea Reabsorption All Sugar All amino acids Mineral Salts Water
  • 17. Function of the Kidney • Filter blood in order to remove cellular waste products from the body. • Maintain chemical composition, pH and water level • At any given time, 20 % of blood is in the kidneys. Humans can function with one kidney. • If one ceases to work, the other increases in size to handle the workload.
  • 18. Cellular waste • urea o (a nitrogenous waste produced in the liver from the breakdown of protein. It is the main component of urine) • uric acid o (usually produced from breakdown of DNA or RNA) • creatinine o (waste product of muscle action).
  • 19. Composition of Chemicals in the Body Substance Blood in Kidney Urine renal artery tubules (filter system) Glucose 2.0 2.0 0 Mineral salts 10.0 10.0 17.0 Amino acids 0.9 0.9 0 Protein 88.0 0 0 Urea 0.5 20.0 20.0 RBC & WBC 47% 0% 0
  • 20. Kidney failure • Urinary Tract Infection • Kidney Stone • Kidney Infection • Diabetic Nephropathy • Hypertension • Glomerulonephritis • HIV nephropathy
  • 22. Treatment of Kidney Failure -Dialysis- • ½ of patients with kidney disease eventually require dialysis • Diffuse harmful waste out of body • Control BP • Keep safe level of chemicals in body • If dialysis cannot work, the patient has to undergo kidney transplant
  • 23. Hemodialysis • 3-4 times a week • Takes 2-4 hours • Machine filters blood and returns it to body
  • 24. Peritoneal Dialysis • Abdominal lining filters blood • 3 types o Continuous ambulatory o Continuous cyclical o Intermittent