1. UNIVERSIDAD AUTÓNOMA DE CIUDAD JUÁREZ
CLORHEXIDINE
DRA. AMARIS MENDOZA ASTRAIN
DR. ALFREDO NEVAREZ RASCÓN

2. History
 Chlorhexidine developed in the 1940s in England,
and was released in 1954 as an antiseptic for skin
wounds. Use in dentistry,initially for disinfection
of the mouth, and from 1970 he popularized the use
of chlorhexidine mouthwash capable of inhibiting the
formation of plaque and gingivitis development.

3.  Chlorhexidine needs to be protected from
light as it breaks easily.
 At high temperatures and decomposes
into chloroaniline the presence of organic
matter not inactive

4. composition
 Chlorhexidine
is an antiseptic bisbiguanidico. This compound
is a strong base and dicationica at pH
levels over 3.5. Nature dicatiónicaof
chlorhexidine makes it
extremely interactive with anions, which
isrelevant to their efficacy, safety and local
side effects.

5. uses in dentistry
 Oral infections for various reasons including those
produced by rubbing of dentures
 Prevention of infection in oral surgery
 Chemotherapeutic prevention of dental caries
 As a disinfectant of cavities prior to sealing

6. Commercial Presentations
 Spray
 Gel
 mouthwash
Fig. 1
http://www.lacer.es/wps/wcm/connect/04ff9a00463daaf
0926e9bc9bb9f72a0/30

7. Chlorhexidine spray
 It has been marketed spray
chlorhedine to the 0.1% and 0.2%
 Prevention and treatment
of gingivitis
 Very delicate state of the
gingiva: Lets you
apply chlorhexidinewithout
touching the affected area
 When rinsing is painful
Fig 2
 Special Patients (physical or http://csimg.mercamania.es/s
mental disabilities) rv/ES/29045327247742/T/34
0x340/C/FFFFFF/url/lacer-
clorhexidina-spray-40.jpg

8. Chlorhexidine Gel
 The gel allows the
selection of sites
affected, leaving the
healthy free,
thus increasing the
safety
margin, chlorhexidine g Fig. 3
els are suitable for http://www.farmahouse.com/images/clorh
exidina%20gel.JPG
prevention and care
of critical areas.

9. Chlorhexidine mouthwash
 Is used in
concentrations of 0.12 to 0.2%,
Indications of rinses
 Cases of excessive formation of plaque.
 Prevention in the treatment of gingivitis.
 People with difficulty performing normal
dental hygiene.
 Mouthwash before or after surgery. Fig 4
http://www.dermofactory.com/160617
 Prevention of dental caries. 6-1155-thickbox/lacer-clorhexidina-
colutorio-200-ml.jpg

10. Precautions
 It is exclusively for local use and not be swallowed
 You can leave a bitter taste after application will
be enhanced if the mouth is rinsed immediately
 Dilute reduces its antimicrobial effect
 Do not use continuously for more than 2-
3 months, and always underprofessional
supervision, as it may have unwanted side effects.

11. side effects
 The adverse effects of this are usually mild and
transient inspecial brown spots on the teeth,
tongue, prosthesis and silicate and
resin restorations and temporary alteration of taste
perception and scaling of the oral mucosa.

12. trademarks
 Paroex.
 Cariax gingival.
 PerioAid alcohol-free.
 Lacer.
 Eludril
Fig. 5
http://scielo.isciii.es/scielo.php?pid=s11
38123x2005000400007&script=sci_artt
ext

13. advantage
 Bactericidal action: antimicrobial effects as good as sodium
hypochlorite
 relatively inocua
 It has no unpleasant odo
 Residual activity of several hours after instrumentation
 Easy storage and handling
 low toxicity

14. Disadvantages
 Staining of the teeth
 staining lingual
 Bitter, metallic taste
 Possible peeling of the oral mucosa
 Stains are accentuated if the patient drinks red
wine, coffee, tea, and a smoking

15. Bibliography
 http://www.odontologosecuador.com/espanol/artodontologos
/gluconato_dental.htm

http://www.encolombia.com/odontologia/odontonet/monogra
fia-clorhexidina4.htm
 http://scielo.isciii.es/scielo.php?pid=s1138-
123x2005000400007&script=sci_arttext