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International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 06 Issue: 4 | Apr 2019 www.irjet.net p-ISSN: 2395-0072
© 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 2597
Diabetes prediction using machine learning
Sudhir Pal1, Sandhya Chauhan2, Meghal Aggarwal3
1,2,3 B.Tech Student, Computer Science, ABES Institute of Technology, Ghaziabad, India
---------------------------------------------------------------------***---------------------------------------------------------------------
Abstract - Diabetes mellitus is one of the most serious health challenges everywhere in the world.
The diabetes mellitus is a classification problem which uses a binary dataset for classification that does the analysis whether a
patient is suffering from the disease or not on the basis of different features available in the dataset. For cleaningthe data, feature
extraction, feature engineering different methods and the procedures are used. And different data mining algorithms canbeused
for prediction on Pima Indians Diabetes Dataset.
This proposed method uses Support Vector Machine (SVM), a machine learning method as the classifier for diagnosis of diabetes.
The experimental results showed that support vector machine can be successfully used for diagnosing diabetes disease which is
giving the highest accuracy among any other algorithm that is testedondatasetinpredictingwhetherthepatientissufferingfrom
diabetes or not. We have also compared the support vector machine algorithm with k-nearest neighbour and the decision tree.
Key Words: radial basis function.RBF
1.INTRODUCTION
Diabetes is one of the common and briskly increasing disease. It is found that the diabetes is a verysevereproblem
in most of the countries. Diabetes is a condition in which your body is unable to produce the required amount of
insulin which is needed to regulate the amount of sugar in the body. This may lead to various diseases like heart
disease, kidney disease, blindness, nerve damage etc. Basically it is foundoutthattherearetwogeneralreasonsfor
diabetes:
(1) The pancreas does not produce enough amount of insulin or the body is not able to produce adequate insulin.
This kind of problem come under Type-1 diabetes problem.
(2) Cells do not respond to the insulin that is produced is come under the Type-2 diabetes problem. Insulin is the
most important hormone that regulates uptake of glucose from the blood into most cells(includingthemuscleand
fat cells). If the amount of insulin presentin the bodyis insufficient, then glucose will have its unusualeffectsothat
glucose will not be absorbed by the body cells that require it. Detection and diagnosis of diabetes at an early will
help the patient to get the early treatment. This will be helpful in preventing the further harm.
2. DIABETES DISEASE DATASET
The Pima Indian diabetes dataset, is used which contains the collection of medical diagnostic reports from 768 records of
female patients.The binary target variable takes the values ‘0’ or ‘1’while ‘1’ in the outcome means a positive test for diabetes,
‘0’ in the outcome means a negative test. There are 268patients in class ‘1’and 500patient value in class ‘0’There are 768 rows
and 9 columns in the dataset. The variables included in the final selection were those which have high discriminative
performance characteristics. for that feature importance graph is plotted ,so that we can find out that what are the important
features that plays an important role in prediction. There are eight numeric variables: (1) Number of times pregnant, (2)
Plasma glucose (3) Diastolicblood pressure (mm Hg) (4)skin fold thickness (mm) (5) serum insulin (mu U/ml)(6)Bodymass
index (7) Diabetes pedigree function (8) Age (years) All of these features are thepartofpima diabetesdataset.Amongall ofthe
above feature glucose, insulin, blood-pressure plays an important role in predicting the Diabetes. Although the dataset is
labelled as there are no missing values, there were some liberally added zeros as missing values. The information about the
missing values as following:
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 06 Issue: 4 | Apr 2019 www.irjet.net p-ISSN: 2395-0072
© 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 2598
It is found that five patients had a glucose of 0, 28 patients had a diastolic blood pressure of 0, 11 patients more had a
body mass index of 0, 192 others had skin fold thickness record of 0, and 140 patients had serum insulin levels of 0. After
the deletion ,it is found that there were 460 cases with no missing values.
Fig -1: Diabetes Dataset
3. GRAPHICAL USER INTERFACE OF THE DIABETES DETECTION SYSTEM
This GUI of the Diabetes Detection System consist of the following fields: 1:patients Name 2. Glucoselevel 3. Bloodpressure 4.
SkinFold thickness 5. Serium insulin 6. Bodymass index. The patient will enter the above mentioned detailed and will click on
the submit button, then the patients detailed will get displayed.Basedon theinformationenteredbythepatient,the system will
predict whether the patient is diabetes or not. This diabetes detection system will make use of the support vector machine
algorithm running in the backend. This support vectormachinealgorithmismakingpredictionwith80%oftheaccuracy,which
is giving the best result among other mining algorithm.
Fig -2: GUI of Diabetes prediciton system
4. METHODOLOGY
4.1 Experimental Classification
The classification of diabetes dataset is developed using the diabetes dataset. The experiments are conducted in Jupyter
Notebook using Anaconda Software. The datasets are stored with MS-Excel doc.
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 06 Issue: 4 | Apr 2019 www.irjet.net p-ISSN: 2395-0072
© 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 2599
Fig -3: Architecture of the proposed model
The diabetes dataset is divided into two parts such that some randomly samples are chosen from the Diabetes dataset,known
as training data and they are trained using the SVM Model. And then the remaining other samples are known as the testing
data, and here the actual prediction is performed using this testing data.The entire code is performed in python and machine
learning concepts are also used. In the proposed model we have divided the entire dataset into 80:20 ratio. 80% of thedataset
data is used for the training purpose so known as the training data. And 20% of the data is known as the testing data. on the
training dataset we are getting the accuracy of 76% while on the testing data we are getting the accuracy of 80.5%.
4.2 Support Vector Machine Algorithm
SVM is very popular and widely used supervised learning classificationalgorithm.Anadvantageofusingthisalgorithmisthatit
can operate in even infinite dimension. SVM finds a hyperplane that leads to a homogeneous partition of data. A good
separation is achieved by the hyperplane that has largest distance to the nearest training datapointsofanyclass.sowehaveto
maximize the margin .The margin is definedasthedistancebetweentheseparatingthehyperplane(decisionboundary) andthe
training samples that are closed to the hyperplane which are called the support vectors. The reason behind having decision
boundaries with the larger margin is that they tend to have a low generalization error(prediction errors) whereas the models
with smaller margins are more prone to the overfitting. We use the parameter ‘c’ to control the width of the margin.For larger
value of ‘c’,the optimizer will choose a smaller margin hyperplane even if that hyperplane does a better job of getting all the
remaining points classified correctly. A very small value of ‘c’ will cause the optimizer to look for a larger margin separating
hyperplane, even if that hyperplane misclassified some points.
Chart -1: when kernel = Linear Chart -2: when kernel=’RBF’
When kernel value=’LINEAR’ is chosen then always the straight line will be drawn and that hyperplane separates the two
different classes. This method is found inefficient to classify when data is in 3-D form or more-higher level. It can only be
applied when data in 2-D form. The RBF kernel stands for the radial basis function.RBF kernels is used to classify the data that
is nonlinearly separable.It has two important parameters: gamma and ‘c’.
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 06 Issue: 4 | Apr 2019 www.irjet.net p-ISSN: 2395-0072
© 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 2600
Gamma: is a parameter of the RBF kernel and can be thought of as the spread of the region.Whenthevalueofthegamma islow
then the curve of the decision boundary is very low and thus leading to the decision region is very broad. When the gamma is
high, the curve of the decision boundary is high which creates island of decision boundaries around the data points.
4.3 K NEAREST NEIGHBORS ALGORITHM
KNN is a supervised machine learning algorithm , or also popular and known as the lazy learning ,because it
doesn’t use the training data at the time of training ,it directly make use of testing data .The k-NN algorithm is the
simplest among all machine learning algorithms .When the size of the dataset is very less so it can easily classify .It
does not perform well with the large dataset.
4.3.1 How this KNN algorithm works
The data which we need to classify to which is class it will belong is known as the test data. let suppose star is the test data, let
we need to find out to which class it will belong, whether it may belong to the red circles or the green squares. For the
classification purpose ,k value will be used .and k represent the neighbours around the test data. value of the k will be the odd
no. let in above example the value of k is chosen as three. It will find out the three nearest neighbours around the test data
with the help of calculating the distance between test data and nearest data using Euclidian distance formula.
KNN algorithm has many disadvantages like it has high computation costs it has to
calculate the distance between test data to nearest neighbours Test data will always belong to those class which has high
majority of particular class in nearest neighbour. It has disadvantage like it gives low accuracy in multidimensional dataset .it
uses the closest point for predicting to which class it will belong, which is found not to be an effective mechanism.
Chart -3: Shows positive correlation
From the above figure we got to know that the followingpairshada positivecorrelationcoefficientbetweenthemascompared
to the other parameters:
1) Pregnancies and Age
2) Insulin and Skin thickness
3) BMI and Skin thickness
4) Insulin and Glucose and with the Outcome value, Glucose and BMI values related the most. This helped us to know that
Glucose and BMI are the parameters we need to take special care of.
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 06 Issue: 4 | Apr 2019 www.irjet.net p-ISSN: 2395-0072
© 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 2601
In our proposed model we divided the entire dataset into 80:20.here 80% of the data is for training and 20% of the data is for
testing. When knn algorithm is performed on the dataset, testing the training dataset got an accuracy of 79% and while
performing the testing on test data got an accuracy of 78%.
Chart -4: Graph between accuracy and neighbour chosen
With this above graph we can conclude that on increasing the value of k, , i.e the nearest neighbour around the test point are
larger in no, then it would be leading to higher accuracy which is beneficial to decide to which class it belongs to.
4.4 Decision Tree
A decision tree is like support tool that uses a tree model for decisions making and their possible consequences, it is a method
that illustrates every possible outcome of a decision. We havecreatedthedecisiontree byusingthegraphvizmoduleinpython.
It is the way which represents an algorithm that contains only conditional control statements. Advantage ofusing thedecision
tree is that in very large size of dataset ,it can easily classify the data. We divided the complete dataset in 80:20 ratios. In our
proposed model, on the training data accuracy is 81.8% and on the test data the accuracy is 76.6%. To have a confirmation on
the best features present in diabetes dataset using Decision Tree. We also plotted the feature importance plot and found that
Glucose and BMI to be the leading and the important parameter present.
Fig -4: Feature importance plot Fig -5: Decision tree
5. CONCLUSIONS
We have applied 1. KNN Algorithm 2. SVM Algorithm 3.DecisionTree on the Pima Indian Diabetes Dataset, and did a lot of
feature manipulation and extraction. We got The best Accuracy of 80% using support vector machinealgorithm.We wereable
to perform a lot of data analysis and came to a conclusion that SVM is a good and practical choice to classify a medical data.
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 06 Issue: 4 | Apr 2019 www.irjet.net p-ISSN: 2395-0072
© 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 2602
REFERENCES
[1] Cortes, C., Vapnik, V., “Support-vector networks”, Machine Learning, 20(2),pp. 273-297, 1995.
[2] Polat, Kemal and Salih Gunes, “An expert system approach basedon principal component analysis andadaptiveneurofuzzyinferencesystemto
diagnosis of diabetes disease,” Expert system with Applications, pp. 702-710, Elseivier, 2007.
[3] I.Tsoulos, D. Gavrilis, E. Glavas,- “Neural network construction and training using grammatical evolution”, Science Direct Neurocomputing
Journal, Vol.72, Issues 13, December 2008,pp. 269-277.
[4] “Feature selection and classification model construction on type 2 diabetic patients‟ data”, Journal of Artificial Intelligence in Medicine, pp
251262, Elsevier, 2008.
[5] Yue, et al. “ An Intelligent Diagnosis to Type 2 Diabetes Based on QPSO Algorithm and WLSSVM,” International Symposium on Intelligent
Information Technology Application Workshops, IEEE Computer Society, 2008.
[6] Barakat,et al. “ Intelligible Support Vector Machines for diagnosis of Diabetes Mellitus.” IEEE Transactions on Information Technology in
Biomedicine, 2009.
[7] https://en.wikipedia.org/wiki/Bin_ary_classification
[8] https://www.webmd.com/a-to-zguides/body-mass-index-bmi-foradults
http://archive.ics.uci.edu/ml/index.php

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IRJET- Diabetes Prediction using Machine Learning

  • 1. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 4 | Apr 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 2597 Diabetes prediction using machine learning Sudhir Pal1, Sandhya Chauhan2, Meghal Aggarwal3 1,2,3 B.Tech Student, Computer Science, ABES Institute of Technology, Ghaziabad, India ---------------------------------------------------------------------***--------------------------------------------------------------------- Abstract - Diabetes mellitus is one of the most serious health challenges everywhere in the world. The diabetes mellitus is a classification problem which uses a binary dataset for classification that does the analysis whether a patient is suffering from the disease or not on the basis of different features available in the dataset. For cleaningthe data, feature extraction, feature engineering different methods and the procedures are used. And different data mining algorithms canbeused for prediction on Pima Indians Diabetes Dataset. This proposed method uses Support Vector Machine (SVM), a machine learning method as the classifier for diagnosis of diabetes. The experimental results showed that support vector machine can be successfully used for diagnosing diabetes disease which is giving the highest accuracy among any other algorithm that is testedondatasetinpredictingwhetherthepatientissufferingfrom diabetes or not. We have also compared the support vector machine algorithm with k-nearest neighbour and the decision tree. Key Words: radial basis function.RBF 1.INTRODUCTION Diabetes is one of the common and briskly increasing disease. It is found that the diabetes is a verysevereproblem in most of the countries. Diabetes is a condition in which your body is unable to produce the required amount of insulin which is needed to regulate the amount of sugar in the body. This may lead to various diseases like heart disease, kidney disease, blindness, nerve damage etc. Basically it is foundoutthattherearetwogeneralreasonsfor diabetes: (1) The pancreas does not produce enough amount of insulin or the body is not able to produce adequate insulin. This kind of problem come under Type-1 diabetes problem. (2) Cells do not respond to the insulin that is produced is come under the Type-2 diabetes problem. Insulin is the most important hormone that regulates uptake of glucose from the blood into most cells(includingthemuscleand fat cells). If the amount of insulin presentin the bodyis insufficient, then glucose will have its unusualeffectsothat glucose will not be absorbed by the body cells that require it. Detection and diagnosis of diabetes at an early will help the patient to get the early treatment. This will be helpful in preventing the further harm. 2. DIABETES DISEASE DATASET The Pima Indian diabetes dataset, is used which contains the collection of medical diagnostic reports from 768 records of female patients.The binary target variable takes the values ‘0’ or ‘1’while ‘1’ in the outcome means a positive test for diabetes, ‘0’ in the outcome means a negative test. There are 268patients in class ‘1’and 500patient value in class ‘0’There are 768 rows and 9 columns in the dataset. The variables included in the final selection were those which have high discriminative performance characteristics. for that feature importance graph is plotted ,so that we can find out that what are the important features that plays an important role in prediction. There are eight numeric variables: (1) Number of times pregnant, (2) Plasma glucose (3) Diastolicblood pressure (mm Hg) (4)skin fold thickness (mm) (5) serum insulin (mu U/ml)(6)Bodymass index (7) Diabetes pedigree function (8) Age (years) All of these features are thepartofpima diabetesdataset.Amongall ofthe above feature glucose, insulin, blood-pressure plays an important role in predicting the Diabetes. Although the dataset is labelled as there are no missing values, there were some liberally added zeros as missing values. The information about the missing values as following:
  • 2. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 4 | Apr 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 2598 It is found that five patients had a glucose of 0, 28 patients had a diastolic blood pressure of 0, 11 patients more had a body mass index of 0, 192 others had skin fold thickness record of 0, and 140 patients had serum insulin levels of 0. After the deletion ,it is found that there were 460 cases with no missing values. Fig -1: Diabetes Dataset 3. GRAPHICAL USER INTERFACE OF THE DIABETES DETECTION SYSTEM This GUI of the Diabetes Detection System consist of the following fields: 1:patients Name 2. Glucoselevel 3. Bloodpressure 4. SkinFold thickness 5. Serium insulin 6. Bodymass index. The patient will enter the above mentioned detailed and will click on the submit button, then the patients detailed will get displayed.Basedon theinformationenteredbythepatient,the system will predict whether the patient is diabetes or not. This diabetes detection system will make use of the support vector machine algorithm running in the backend. This support vectormachinealgorithmismakingpredictionwith80%oftheaccuracy,which is giving the best result among other mining algorithm. Fig -2: GUI of Diabetes prediciton system 4. METHODOLOGY 4.1 Experimental Classification The classification of diabetes dataset is developed using the diabetes dataset. The experiments are conducted in Jupyter Notebook using Anaconda Software. The datasets are stored with MS-Excel doc.
  • 3. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 4 | Apr 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 2599 Fig -3: Architecture of the proposed model The diabetes dataset is divided into two parts such that some randomly samples are chosen from the Diabetes dataset,known as training data and they are trained using the SVM Model. And then the remaining other samples are known as the testing data, and here the actual prediction is performed using this testing data.The entire code is performed in python and machine learning concepts are also used. In the proposed model we have divided the entire dataset into 80:20 ratio. 80% of thedataset data is used for the training purpose so known as the training data. And 20% of the data is known as the testing data. on the training dataset we are getting the accuracy of 76% while on the testing data we are getting the accuracy of 80.5%. 4.2 Support Vector Machine Algorithm SVM is very popular and widely used supervised learning classificationalgorithm.Anadvantageofusingthisalgorithmisthatit can operate in even infinite dimension. SVM finds a hyperplane that leads to a homogeneous partition of data. A good separation is achieved by the hyperplane that has largest distance to the nearest training datapointsofanyclass.sowehaveto maximize the margin .The margin is definedasthedistancebetweentheseparatingthehyperplane(decisionboundary) andthe training samples that are closed to the hyperplane which are called the support vectors. The reason behind having decision boundaries with the larger margin is that they tend to have a low generalization error(prediction errors) whereas the models with smaller margins are more prone to the overfitting. We use the parameter ‘c’ to control the width of the margin.For larger value of ‘c’,the optimizer will choose a smaller margin hyperplane even if that hyperplane does a better job of getting all the remaining points classified correctly. A very small value of ‘c’ will cause the optimizer to look for a larger margin separating hyperplane, even if that hyperplane misclassified some points. Chart -1: when kernel = Linear Chart -2: when kernel=’RBF’ When kernel value=’LINEAR’ is chosen then always the straight line will be drawn and that hyperplane separates the two different classes. This method is found inefficient to classify when data is in 3-D form or more-higher level. It can only be applied when data in 2-D form. The RBF kernel stands for the radial basis function.RBF kernels is used to classify the data that is nonlinearly separable.It has two important parameters: gamma and ‘c’.
  • 4. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 4 | Apr 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 2600 Gamma: is a parameter of the RBF kernel and can be thought of as the spread of the region.Whenthevalueofthegamma islow then the curve of the decision boundary is very low and thus leading to the decision region is very broad. When the gamma is high, the curve of the decision boundary is high which creates island of decision boundaries around the data points. 4.3 K NEAREST NEIGHBORS ALGORITHM KNN is a supervised machine learning algorithm , or also popular and known as the lazy learning ,because it doesn’t use the training data at the time of training ,it directly make use of testing data .The k-NN algorithm is the simplest among all machine learning algorithms .When the size of the dataset is very less so it can easily classify .It does not perform well with the large dataset. 4.3.1 How this KNN algorithm works The data which we need to classify to which is class it will belong is known as the test data. let suppose star is the test data, let we need to find out to which class it will belong, whether it may belong to the red circles or the green squares. For the classification purpose ,k value will be used .and k represent the neighbours around the test data. value of the k will be the odd no. let in above example the value of k is chosen as three. It will find out the three nearest neighbours around the test data with the help of calculating the distance between test data and nearest data using Euclidian distance formula. KNN algorithm has many disadvantages like it has high computation costs it has to calculate the distance between test data to nearest neighbours Test data will always belong to those class which has high majority of particular class in nearest neighbour. It has disadvantage like it gives low accuracy in multidimensional dataset .it uses the closest point for predicting to which class it will belong, which is found not to be an effective mechanism. Chart -3: Shows positive correlation From the above figure we got to know that the followingpairshada positivecorrelationcoefficientbetweenthemascompared to the other parameters: 1) Pregnancies and Age 2) Insulin and Skin thickness 3) BMI and Skin thickness 4) Insulin and Glucose and with the Outcome value, Glucose and BMI values related the most. This helped us to know that Glucose and BMI are the parameters we need to take special care of.
  • 5. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 4 | Apr 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 2601 In our proposed model we divided the entire dataset into 80:20.here 80% of the data is for training and 20% of the data is for testing. When knn algorithm is performed on the dataset, testing the training dataset got an accuracy of 79% and while performing the testing on test data got an accuracy of 78%. Chart -4: Graph between accuracy and neighbour chosen With this above graph we can conclude that on increasing the value of k, , i.e the nearest neighbour around the test point are larger in no, then it would be leading to higher accuracy which is beneficial to decide to which class it belongs to. 4.4 Decision Tree A decision tree is like support tool that uses a tree model for decisions making and their possible consequences, it is a method that illustrates every possible outcome of a decision. We havecreatedthedecisiontree byusingthegraphvizmoduleinpython. It is the way which represents an algorithm that contains only conditional control statements. Advantage ofusing thedecision tree is that in very large size of dataset ,it can easily classify the data. We divided the complete dataset in 80:20 ratios. In our proposed model, on the training data accuracy is 81.8% and on the test data the accuracy is 76.6%. To have a confirmation on the best features present in diabetes dataset using Decision Tree. We also plotted the feature importance plot and found that Glucose and BMI to be the leading and the important parameter present. Fig -4: Feature importance plot Fig -5: Decision tree 5. CONCLUSIONS We have applied 1. KNN Algorithm 2. SVM Algorithm 3.DecisionTree on the Pima Indian Diabetes Dataset, and did a lot of feature manipulation and extraction. We got The best Accuracy of 80% using support vector machinealgorithm.We wereable to perform a lot of data analysis and came to a conclusion that SVM is a good and practical choice to classify a medical data.
  • 6. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 4 | Apr 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 2602 REFERENCES [1] Cortes, C., Vapnik, V., “Support-vector networks”, Machine Learning, 20(2),pp. 273-297, 1995. [2] Polat, Kemal and Salih Gunes, “An expert system approach basedon principal component analysis andadaptiveneurofuzzyinferencesystemto diagnosis of diabetes disease,” Expert system with Applications, pp. 702-710, Elseivier, 2007. [3] I.Tsoulos, D. Gavrilis, E. Glavas,- “Neural network construction and training using grammatical evolution”, Science Direct Neurocomputing Journal, Vol.72, Issues 13, December 2008,pp. 269-277. [4] “Feature selection and classification model construction on type 2 diabetic patients‟ data”, Journal of Artificial Intelligence in Medicine, pp 251262, Elsevier, 2008. [5] Yue, et al. “ An Intelligent Diagnosis to Type 2 Diabetes Based on QPSO Algorithm and WLSSVM,” International Symposium on Intelligent Information Technology Application Workshops, IEEE Computer Society, 2008. [6] Barakat,et al. “ Intelligible Support Vector Machines for diagnosis of Diabetes Mellitus.” IEEE Transactions on Information Technology in Biomedicine, 2009. [7] https://en.wikipedia.org/wiki/Bin_ary_classification [8] https://www.webmd.com/a-to-zguides/body-mass-index-bmi-foradults http://archive.ics.uci.edu/ml/index.php