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A RAPID TEST FOR FUNGUS THAT CAUSED
 INJECTION DEATHS IS ANNOUNCED AND
BLOOD-BASED BIOMARKERS MAY LEAD TO
   EARLIER DIAGNOSIS OF PARKINSON´S
                DISEASE

     MARIA CAMILA JARAMILLO MONSALVE
             MEDCINE STUDENT
INTRODUCTION

     Polymerase chain reaction
     allows amplification of small
     DNA fragments



     Real time PCR is a useful method
     for     the       detection     and
     quantification of infectious agents
A RAPID TEST FOR FUNGUS THAT
 CAUSED INJECTION DEATHS IS
         ANNOUNCED


    Newswise. January 9 of 2013.
    Source newsroom: University of
    Medicine and Dentistry of New
    Jersey (UMDNJ)
A RAPID TEST FOR FUNGUS THAT CAUSED
   INJECTION DEATHS IS ANNOUNCED

                 Marketing of a contaminated
                 steroid medication by an
                 infectious fungus causes
                 some patients deaths.


                  The detection of this fungus
                  in biofluids is difficult,
                  because he tends not to be
                  free-floating in the samples.
A RAPID TEST FOR FUNGUS THAT CAUSED
   INJECTION DEATHS IS ANNOUNCED


The development of a
sensitive and effective essay
allows a rapid detection of
the fungus in samples.


  The essay is very useful
  to   get     an    early
  diagnostic.
A RAPID TEST FOR FUNGUS THAT CAUSED
   INJECTION DEATHS IS ANNOUNCED


The assay is based on the
use of molecular TEST FOR FUNGUS THAT CAUSED
            A RAPID
                      beacon
technology in real time PCR. IS ANNOUNCED
            INJECTION DEATHS




  This is a fast method
  to detect the fungus
  and            prevent
  consequences
OBSERVATION
     I think that the creation of specific
     and immediate assay to detect the
     presence of the infecting fungus can
     decrease the consequences of a
     mistake that could cost the lives of
     many people, and provide an
     effective way to create another
     similar methods to detect infectious
     diseases quickly to lower the rates of
     morbimortality
BLOOD-BASED    BIOMARKERS
MAY   LEAD   TO    EARLIER
DIAGNOSIS OF PARKINSON´S
         DISEASE
              Science Daily

  Sok Kean Khoo, David Petillo, Un
  Jung Kang, James H. Resau, Brian
  Berryhill , Jan Linder, Lars Forsgren,
  Leslie A. Neuman, Aik Choon
  Tan.     Plasma-Based       Circulating
  MicroRNA         Biomarkers         for
  Parkinson's Disease. Journal of
  Parkinson's Disease, Volume 2/Issue 4
  (December 2012) DOI: 10.3233/JPD-
  012144
BLOOD-BASED BIOMARKERS MAY LEAD
TO EARLIER DIAGNOSIS OF PARKINSON´S
              DISEASE


  Parkinson´s disease is a
  neurodegenerative
  process.

The differential diagnostic is
based in the evaluation of motor
functions through a subjective
clinical rating scales.
BLOOD-BASED BIOMARKERS MAY LEAD
TO EARLIER DIAGNOSIS OF PARKINSON´S
              DISEASE


                  The loss of dopaminergic
                  neurons    causes    motor
                  abnormalities, specific of
                  Parkinson´s disease.




                   That’s the reason why its
                   diagnosis take a lot of
                   time.
BLOOD-BASED BIOMARKERS MAY LEAD
TO EARLIER DIAGNOSIS OF PARKINSON´S
              DISEASE



The researchers identified
and tested the first blood-
based circulating microRNA
biomarkers for PD.
OBSERVATION
I think it´s amazing how the
search for diagnostic methods
more specific and sensitive, they
can give a pertinent treatment
for PD patients and this way to
prevent motor and cognitive
irreversible consequences.
MEDICAL UTILITY



     The     new   molecular
     techniques to detect
     infectious agents or
     diseases allows an early
     diagnostic.
MEDICAL UTILITY



This      methods     can
anticipate     therapeutic
interventions and prevent
the fatal consequences.
MEDICAL UTILITY
        The   detection   of
        fungal infections in
        drugs



       An effective way to prevent
       the sale of contaminated
       medicaments.
MEDICAL UTILITY
Blood-based biomarkers pretends
improving the PD diagnostic to
prevent irreversible loss of motor
abilities
BIBLIOGRAPHY

[http://www.sciencedaily.com/releases/2013/01/1301201
45842.htm] checked on Juanary 7th of 2013.”Blood
Based Biomarkers May Lead to Earlier Diagnosis of
Parkinson's Disease”

[http://www.newswise.com/articles/a-rapid-test-for-
fungus-that-caused-injection-deaths-is-announced]
checked on January 6th of 2013. “A Rapid Test for
Fungus That Caused Injection Deaths Is Announced”

 Martínez, Lina María; Vargas, Natalia ; Toro, Eduardo;
Pamplona, Ana P; Quevedo, Esteban O. “Biología
molecular”. Ed 7. 2012 . Pp 121
Felicia Simion

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Folding maria camila jaramillo

  • 1. A RAPID TEST FOR FUNGUS THAT CAUSED INJECTION DEATHS IS ANNOUNCED AND BLOOD-BASED BIOMARKERS MAY LEAD TO EARLIER DIAGNOSIS OF PARKINSON´S DISEASE MARIA CAMILA JARAMILLO MONSALVE MEDCINE STUDENT
  • 2.
  • 3.
  • 4. INTRODUCTION Polymerase chain reaction allows amplification of small DNA fragments Real time PCR is a useful method for the detection and quantification of infectious agents
  • 5. A RAPID TEST FOR FUNGUS THAT CAUSED INJECTION DEATHS IS ANNOUNCED Newswise. January 9 of 2013. Source newsroom: University of Medicine and Dentistry of New Jersey (UMDNJ)
  • 6. A RAPID TEST FOR FUNGUS THAT CAUSED INJECTION DEATHS IS ANNOUNCED Marketing of a contaminated steroid medication by an infectious fungus causes some patients deaths. The detection of this fungus in biofluids is difficult, because he tends not to be free-floating in the samples.
  • 7. A RAPID TEST FOR FUNGUS THAT CAUSED INJECTION DEATHS IS ANNOUNCED The development of a sensitive and effective essay allows a rapid detection of the fungus in samples. The essay is very useful to get an early diagnostic.
  • 8. A RAPID TEST FOR FUNGUS THAT CAUSED INJECTION DEATHS IS ANNOUNCED The assay is based on the use of molecular TEST FOR FUNGUS THAT CAUSED A RAPID beacon technology in real time PCR. IS ANNOUNCED INJECTION DEATHS This is a fast method to detect the fungus and prevent consequences
  • 9. OBSERVATION I think that the creation of specific and immediate assay to detect the presence of the infecting fungus can decrease the consequences of a mistake that could cost the lives of many people, and provide an effective way to create another similar methods to detect infectious diseases quickly to lower the rates of morbimortality
  • 10. BLOOD-BASED BIOMARKERS MAY LEAD TO EARLIER DIAGNOSIS OF PARKINSON´S DISEASE Science Daily Sok Kean Khoo, David Petillo, Un Jung Kang, James H. Resau, Brian Berryhill , Jan Linder, Lars Forsgren, Leslie A. Neuman, Aik Choon Tan. Plasma-Based Circulating MicroRNA Biomarkers for Parkinson's Disease. Journal of Parkinson's Disease, Volume 2/Issue 4 (December 2012) DOI: 10.3233/JPD- 012144
  • 11. BLOOD-BASED BIOMARKERS MAY LEAD TO EARLIER DIAGNOSIS OF PARKINSON´S DISEASE Parkinson´s disease is a neurodegenerative process. The differential diagnostic is based in the evaluation of motor functions through a subjective clinical rating scales.
  • 12. BLOOD-BASED BIOMARKERS MAY LEAD TO EARLIER DIAGNOSIS OF PARKINSON´S DISEASE The loss of dopaminergic neurons causes motor abnormalities, specific of Parkinson´s disease. That’s the reason why its diagnosis take a lot of time.
  • 13. BLOOD-BASED BIOMARKERS MAY LEAD TO EARLIER DIAGNOSIS OF PARKINSON´S DISEASE The researchers identified and tested the first blood- based circulating microRNA biomarkers for PD.
  • 14. OBSERVATION I think it´s amazing how the search for diagnostic methods more specific and sensitive, they can give a pertinent treatment for PD patients and this way to prevent motor and cognitive irreversible consequences.
  • 15. MEDICAL UTILITY The new molecular techniques to detect infectious agents or diseases allows an early diagnostic.
  • 16. MEDICAL UTILITY This methods can anticipate therapeutic interventions and prevent the fatal consequences.
  • 17. MEDICAL UTILITY The detection of fungal infections in drugs An effective way to prevent the sale of contaminated medicaments.
  • 18. MEDICAL UTILITY Blood-based biomarkers pretends improving the PD diagnostic to prevent irreversible loss of motor abilities
  • 19. BIBLIOGRAPHY [http://www.sciencedaily.com/releases/2013/01/1301201 45842.htm] checked on Juanary 7th of 2013.”Blood Based Biomarkers May Lead to Earlier Diagnosis of Parkinson's Disease” [http://www.newswise.com/articles/a-rapid-test-for- fungus-that-caused-injection-deaths-is-announced] checked on January 6th of 2013. “A Rapid Test for Fungus That Caused Injection Deaths Is Announced” Martínez, Lina María; Vargas, Natalia ; Toro, Eduardo; Pamplona, Ana P; Quevedo, Esteban O. “Biología molecular”. Ed 7. 2012 . Pp 121